For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTAPNTRRVDRVPLSRSQQNIYNGMLQDNDPALYFIGKSYRFHQLELSVFLAALEATILKNPGQLCVLEA PSTEGDYPDLVPRLQFGDIVRVRSDEQPQTDSRDYDLMHAWSPDILAKPLVRYTVRTDKNGFVARLDVFT HHILVDGGAIRIIEENLAHHLDTDNRLEIPCIRQALDKLAEAHRREATKVEESLQRLANVVQRELADEVR NGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALSETKQVPLNILVATAAVAVDASLRQSTEGLLVH AVDNRFGDPYLDVATCLVNSVAHSIRFPPFASVQDVVRTLDRSYVKAIRLRWLREEYYRRIYLALNQTSH IEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEGMTVACVLNEDERTLDLSIWNRVDLPQGKSCTRVAK RIAAALELMAAAWDQPIAMIVNEWFGISSDGALCLGNEVTQTTRPLAPAWFLDPGGSVHLTVDKRRYVHP WIAWLVRGSVVPGDVLVFTDDNTDKTIDLLIACHLAGCGYSVCDTVAEVPLRAKAITDHGGGVSARVIDV AATQLAVTPDNEQSKLADKLIKQAAQDISLADKTAYIMPTSGSTGQPKLVQVSHGSLALFCDAVRNAYGW GAHDTILQCAPLTSDISVEEIFGGAICGSKLVRSTAMKTGDLAELARDIFVQRATVIDLPTAVWHLLCDH SDAIDEINRSCLRQIVIGGEAVRPCAVDKWIDSGASQGISLMSTYGPTETTVVVTYLPIVCAPMTVESDA RLRLGWPIVPNTVFIAFGELVIVGDLVSVGYLGIDSRNFGTVTTTDGSCRRAFATADCVILDDEGFPVFS GRKDAVVKISGKRVDTAELIRRISTDPNVSDVAVEVYNGRLGVWFETKLTREGVDDAAAATRSRLILASL GVSSFFVVGVPCIPRKPNGKIDRDNLLVMPQLVDSVQNYAGSGEGAAGLAEIWSRHLGRAILPDSSLLDE GIGSVDLIRILPDTRRHLGRHLSLLDLISADNAANLTAAQTANVWMDVGTAAEIERDLASLCRQRNATEF SVKQTRNSHQKQAIVVLGASGILGTGFAQAVLDLRQSGVLCPEVVLATRARLPEGDPWTALQGVDGVRIE RISFENGPGELEALIRDTDAGTLVNGVGNTNMLVPYRELRLANVELVSAIVDICASYSTRLVHLSSFVVN ADVTVPQVTDPRETPYPYAASKSLAELVVAGSPSALDFTIVRLPRVLGEDYQLRNSSDILLSIVDACIAL RAYPSATVTEEVTTGRAAAKAILGVVSALARSGQLGSGISVVRGEAVAYADFLSEFASDELNMAEWKYRL DQSDWAKRNPRRWSVIDAWFTLGMMFEMRSYAEYPTMALGVESVAELAAPPESIRALLAHGCSQPLKYTG R
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_01996 | nrp | - | 100% (1401) | putative peptide synthase |
M. leprae Br4923 | MLBr_01051 | xclC | 2e-09 | 25.17% (298) | acyl-CoA synthetase |
M. leprae Br4923 | MLBr_00243 | - | 2e-09 | 23.64% (385) | long-chain-fatty-acid--CoA ligase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 0.0 | 69.05% (1008) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_2696 | - | 1e-24 | 27.19% (445) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv0101 | nrp | 0.0 | 69.05% (1008) | peptide synthetase |
M. abscessus ATCC 19977 | MAB_0663 | - | 0.0 | 56.22% (1391) | cyclic synthetase (peptide synthase) |
M. marinum M | MMAR_0256 | - | 0.0 | 61.99% (1410) | non-ribosomal peptide synthetase |
M. avium 104 | MAV_3239 | - | 2e-25 | 28.00% (450) | syringomycin synthetase |
M. smegmatis MC2 155 | MSMEG_0019 | - | 7e-26 | 27.87% (445) | amino acid adenylation |
M. thermoresistible (build 8) | TH_3141 | - | 2e-23 | 26.83% (451) | PUTATIVE amino acid adenylation domain |
M. ulcerans Agy99 | MUL_4858 | - | 0.0 | 61.70% (1410) | non-ribosomal peptide synthetase |
M. vanbaalenii PYR-1 | Mvan_3845 | - | 9e-26 | 27.42% (445) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 MTADSLDIAELLELWNNHSTPERTSTVPTLFAAQCALTPDEVAVVDGERR MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LTYRHLETHVAQLAHAVRVAAGEGPEPIVAIGVPRSAEMVVCVLAAMMAG MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VAFVPLDPSWPAHRRRQVLADSGAVATFITREDESDWGVPGLRVDLGAWQ MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FTAESPVLPQADVHPAQLAYVIFTSGSTGKPKGAMIRHDAIAERLQWQRD MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HILHFGKHDHTDASLFKAPLSFDISVNEILLPLVSGGRVVVAVPDGEKDP MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 EYLLELIRTEQVTFVYLVSSMLDTLLELDRLATADGAPSSLASLRHVWCG MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GEVLTPGLFARFRKQLTTTLYHGYGPAEATIGVSHVIYRDTAERIATSIG MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPNPHTQLYVLDEYLRPVPPGVGGELYAAGFLLGRGYVNAPSLTASRFVA MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NPFDGNGSRMYRTGDLARWTEDGSLEFLGRADNQVKIGGRRVELEEIESQ MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LADHPAVRHAVVDVHRQGGADVLVGYLVAADGVRNDAAWHAEVADWARTR MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LPEYMVPKAFVALDQVPLTANGKTDRRALPAPDLERSGTVKPPRTPRETV MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LCQVFADALDIDAVGVDEDFFALGGDSIVAIRVVSRLRAAGYTLRPRDMF MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AHRTVEALAPLLGDSDVRDTGPAVDPTGAATPTPILRWLDEVGTAGSVLN MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GFHQGMSLVTPADADENTLRAAIAATVRRHHVLWAPPGRTASDIDIPGTP MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PETRLLIADASDGIPAQAEKVARQLVSLLDTARIAFGWIRRPAAPGRLVV MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IADHTVIDGVSLRILAEDIATAYGLIAEGRAVELPTPHTSWRAWAQRLAD MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TAAAGGFDADLEHWQQVCATTETPWGDRALDPAIDTVATESRLTVELPSA MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VTDAILTTVPDRIHGHVNDALVAALYLALRRWLHTRGVGADTLLVEMEGH MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GREGHLVDSDTAGLDLSNTVGWFTTLYPVALRDAEFDWQAAVSGGPQLGA MAV_3239|M.avium_104 ----------------------------------------------MLGV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVRSVKDQLRSVPSHGFSYGALRYLRDGTSGLEAAPQVLFNYLGRFGTAD MAV_3239|M.avium_104 GRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLAP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPWALANDTTAVLEDRDPGMPLPRLLEVNAEAVTTADGSVLRATFSWPAH MAV_3239|M.avium_104 RVRGGGRTLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMAAALK Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVAEVDVRTLAGMWTDLLTAIASSDDVRGHSASDFDRVSVTADDVAELER MAV_3239|M.avium_104 LQGPLDVSVLRAALADVIARHESLRTVFAVSDGTPHQVVIPAEQADIGWD Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RYPGLTDLLPLTPTQQGIYFHSTFSRDRDPYVVQQIVDITGPLDTERFQR MAV_3239|M.avium_104 VVDTAG--WSPARMKEAIDAAAGHAFDLSTEIPLRATLFRNSLDEHVLVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ATESVAARHRALGAVFTTLSDGTPVAVHAATVAPDFDVLDARHAADPSTV MAV_3239|M.avium_104 VAHHIAADGSSLNPLLRDLTAAYTARCAG--------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VAQRARWERERRFDLAAAPLTRYTLVRRRDDLHTMIETVHHIVADGWSVP MAV_3239|M.avium_104 ----------RVPDWVPLPVQYIDYALWQRAQFGDLEDPDSPIAGQLRYW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IVLDDLLTAYAGDDFDGPAPEFARFVDWLEQRDTDSDRAAWAPALEDITE MAV_3239|M.avium_104 QEALAGLPERLALPTDRPYPAVADHRGARVDIDWPASLQQQVSALARVHN Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PTRLAAADGARGRTTGSGFGTRTVTLQSRSAVADAANGAAVTVGTLLHTA MAV_3239|M.avium_104 ATSFMVVQAG-----------------LAVLLAKLGASCDVAVGFPIAGR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 WGLALGRLTGRDDVVFGTVVSGRGADVHGIESMVGLLVNTVPVRVAWSAD MAV_3239|M.avium_104 GDPALDDLVGFFVNTLVLRVDLSGDPTVGEILARVRQRSLAAYEHQDVPF Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DTGADVAGRLAAVESTLLEHHHLPLTEAHRLAGVGELFDTLVVIENLGAT MAV_3239|M.avium_104 EILVERLNPTRSLAHHPLIQVMLTWRGDDPTRLRLGELEVAALPIDIGTA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 THTRGDLTLGDIGVIEAPHYPLTLMISVRDTITVTVTNDREHVSDVLADT MAV_3239|M.avium_104 RMDLTFSLCERWTEEGRPAGIAGTVEFRTDVFDADTIRTLTERLRRVLDV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVAAFTEVLTALTADPGVSPGDIALPAPQATAPPTQAPQTVTDLIAAAIA MAV_3239|M.avium_104 LTADPGRHLSSIEVLEDTEFARLDIFGNRAALGRSTTGASVPALFGAWAQ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 EHRDDIALVVGETEWTYGQLGARAGELAAALAEAGVRRGDIVALATARSA MAV_3239|M.avium_104 RVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLLDRSA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DLVAAIWAIIAAGAAYLPVDLAYPRTRIEYMLRHARPTAVIADGVGAHVV MAV_3239|M.avium_104 EAVVAILGVLKAGAAYVPMDPAVPAARIAFIVADADLRVVVTDAGSRSRL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SGA-LPADTIVVSTTATHAAVPFTPVPVDGADAVSVLYTSGSTGEPKAVV MAV_3239|M.avium_104 TGLGAAIVDLDDPALADYPATEPAGPGPAAGDIAHVIYTSGTTGEPKGVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GTHA---ALANRLAWAVEAWPAATRIAKSPLSFIDGTTELLAGLAAGART MAV_3239|M.avium_104 VSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVWEIWAALLHGGRL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VLAGDETARDGRRLAQLVAAHGVEQLLAVPSLAAVLADERTEDVAELNRW MAV_3239|M.avium_104 VVVSDAVARSPDDLRRLLIRERVTVLTQTPSAAGALSPQGLDSVALVIG- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IVSGEALEPRHLHALRTACPTAEIVNSYGSSEVAGDVLAGVQDDAGITLG MAV_3239|M.avium_104 ---AEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPLAAGSGAPPIG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AAVPGAGIRILDSRLRQLPAGVIGEIYVTGGQLARGYLGRPGQTATRFVA MAV_3239|M.avium_104 SPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 A---PGGERMYRTGDLGALLPGGRVVFAGRADDQLKINGHRVEPGEIESV MAV_3239|M.avium_104 CPFGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LARQPGVREAAVIG--TGTQLAAFVVLESDAPGAGDLLTAVSAELPGHLV MAV_3239|M.avium_104 LTDLDGVEQAAVIAREDSPGHKRLVAYLTGTADPAQVRTQLADRLPGYML Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PSSLRPVDAIPLLPNGKRDNNALRSLLVPGESTGTAPTNDVERAVLDVMT MAV_3239|M.avium_104 PSAVLALDALPLTVNGKLDTRALPAPELRAENRYRAPQNPTEESLADVYA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GVLGRDPLGADDDFFAVGGDSISAIRVTSRLARAGYHIATEDVFRGRTAA MAV_3239|M.avium_104 RLLGLERVGVDDSFFELGGDSLSAMRLITAVN------------------ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GVAALVDTVESLAHDAAIEPFATVRLSPQTIDRIRESGQVEDIWAMSPLQ MAV_3239|M.avium_104 AELDADLTVRALFEAPTVAQLAPRVAAGTGRAGRLVAAERPAVLPLSFAQ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LGVYYQSTLADAGPTYIAQNVFEFDRRIDVDAMRRAFTALLRRHPQLRAG MAV_3239|M.avium_104 SRLWFIDQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRTL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FRTVEHAEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQDDPAAAQHIVDT MAV_3239|M.avium_104 FP---------APDGAPRQVVLEAERAEVDWQVVDAARWPASWLAEATHE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DRTAPFDVATPPLLRLTVIRLPGGRDRMLFTYHFLLFDGWSRELVLRDLF MAV_3239|M.avium_104 AARYTFDLATEIPLRAWLFRRNHDEHVLVAVVHHIAADGWSLTPLVRDLG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ALYDSDAQHG------AIAPHGDLVVRHLQWLATDGDPQASGARDAWRDL MAV_3239|M.avium_104 AAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPDSPIATQLQYWQ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LAGLTEPTLASGVSPDHPDARPGTEPGRIVVRVPEDVTTQLHTCATAHGA MAV_3239|M.avium_104 RALAGMPERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLARTHNA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TLNSVVTAAVALVTGYHAGTTDVVIGTTVAGRPGHLVGIDETIGLFLNTV MAV_3239|M.avium_104 TSFMVVQAALAVLLSTLSANPDVAVGFPIAGRRD--PALDDVVGFFVNTL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PVRVDMSPTRSVAAAMASIGEQRVAMMRHDHLGLGQIQRAAGDSGSALFD MAV_3239|M.avium_104 VLRVDLADDPSIAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAHH Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SLLVLQNFLDDDTFTDLESRHGIVDVSYHDTTHFPLTWVLTPGRELAIK- MAV_3239|M.avium_104 PLVQVMLAWQNNDPVDVSLGDVHVTPMPLENQVARMDLVWSLAERWTADG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ----------LEHRVVDDARATEMVEQLVTVLRTIAAEPDTAVGAVDLIG MAV_3239|M.avium_104 RPDGIDGTVEFRTDVFDAASIETLVRRLQRVLLAMTADPARPVSSIDILD Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ADRRAQLERR---WSSTERPLEPVTIAELLARRAEQNPDDVALVFGAQSV MAV_3239|M.avium_104 EPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAVAISCGERSW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TYREFDDRVSQFARHLRARGAAPETFVALALPRSIDMVVALFAVLRAGAA MAV_3239|M.avium_104 TYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YLPLELDLPIDRLRTIIDNAEPVLLVTTTDRTELIGHARARGADVIALDD MAV_3239|M.avium_104 YVPIDPGLPSARIDFMLADAVPVVTVTTAELRASAGDPDRVVAIDDPAPH Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AETAATLADTPAHPLTAGELGAFASDSTRLNHPAYLIYTSGSTGRPKGVL MAV_3239|M.avium_104 VPRIG------------------GRAAPAPDDIAYVIYTSGTTGVPKGVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TGYAGLTNMYFNHREAIFAPTVARAGSAEQLRIAHTVSFSFDMSWEELFW MAV_3239|M.avium_104 VTHHNVTQLLGSLDDRLGLGRVWSQCHSLAFDFS---------VWEIFGA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LVEGHQVHVCDEELRRDAPALVAYCHRHRIDVINVTPTYAHHLFDAGLLD MAV_3239|M.avium_104 LLRGGRLVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPE---- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DGAHTPPLVLLGGEAVGDGVWSALRDHPDSAGYNLYGPTEYTINTLGGGT MAV_3239|M.avium_104 --RLESVALVLGGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DDSDTPTVGQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGYHRRA MAV_3239|M.avium_104 AGGAAVPIGSPVPGAALFVLDGRLRRVPPGVVGELYVAGRGVAAGYLGRA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GLTAATMVADPY-VPGGRMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRG MAV_3239|M.avium_104 ALTASRFVACPFGGTGTRMYRTGDLARWGADG--QLHYVGRADEQVKIRG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YRVELGEIESVLTRADGVARCAVVARATGANPPVKTLAAYVIPDRWPAED MAV_3239|M.avium_104 FRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYITGTADP----- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AAFITGLRDHLARVLPGYMVPTRYGIVDTLPLTINGKLDVAALPEPIAAT MAV_3239|M.avium_104 ----AELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDYAG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SGTGRTPRTDREATLLEIVASVLGIDGIGVDDDFFTLGGDSISSISVCGR MAV_3239|M.avium_104 -GRYRAPGDAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ARKAGLNITPRDVFRRRTIAALA--ASADTTQTPESGPDTGTGAITATPM MAV_3239|M.avium_104 ARAAGVMCTARDVFVEQTVARLARVVTVAAADGELGAADEGIGPVQPTPI Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LAETAQANTPLTNFYQAMVLATPAGITAHEVQRVLQTVVDAHAMLRARLV MAV_3239|M.avium_104 MRWLQDIDGPIDEFNQTMVLAAPAGVSQSDVAVVLQALLDRHPMLRLCLD Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TTATG-WTLTVPDQTAAIGLTVRSGALTSDCVEAEKAAAAAELDPRAGNM MAV_3239|M.avium_104 DDGAGGWDLHVPPPGSVDARPILR--TVDVLSEAALARARARLNPGAGLM Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VRAVWFDAPEASGQLLLVIHHLVIDGVSWRILSEDLSRAWNDLAAGRDVA MAV_3239|M.avium_104 LSAVWAS---ETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHHSGQEIA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ADAVPTSFHTWANALAQRTFDDESEYWADVLATPDPDLGSRPPDPAIDTA MAV_3239|M.avium_104 LPVPGTSFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPDDTY Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DTVRSHEVTLASDVTEALLTSVPAAMHGGVNDVLLTGLAVALAQWRADRG MAV_3239|M.avium_104 ASAGQLSASLDVQTTRLLLGEVPAAFHAGVQDILLIAFGLACTEFVGGG- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HSQNTAAVISLEGHGRESDLVAADLDLSRTVGWFTSIYPVRIDPGPLEWD MAV_3239|M.avium_104 ----APIGIDVEGHGRHEEIASG-VDLSRTVGWFTTKYPVALRMSRRLDW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVRSAGAELAAAAKAVKEQLRAVPNRGLGYGVLRHLHGALDG--TPPQIL MAV_3239|M.avium_104 ARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEIEVQGPDPVIG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FNYLGRFTGGSGNDWRPVAGIGALTEGVDPSNPAMSLEI------NALAE MAV_3239|M.avium_104 FNYLGRLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELNAGTM Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ERPDGTVLSMTLAWPGGLLDADDVSELGSMWADVLVALTRCDALRG--HT MAV_3239|M.avium_104 DTDAGPQLHANWTWARSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PSDFGLVTVSQDDIDGWDRLGEVEEVLPLLPLQEGMYFHSMFGDPATDTY MAV_3239|M.avium_104 PSDIAPTRLDQGRIEQLERRYDVADILPLTPLQQGLLFHATGSHAEGDVY Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RVQQIAQLSGPVDPEVLRTSLTVVMRRHQALRASFNELTDG-----RVAQ MAV_3239|M.avium_104 AVQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VIWSDVPVQLTVVDTDDLESIAAEELARPFNLAEAPLVRYMLVRLGDDDH MAV_3239|M.avium_104 EIAWRYLELDASDVDEQLEQLSADERAAVRELGDRPPFGAALIRTADTEH Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RLVQTMHHIIADGWSYPVLFGDIVDHYNAAIGVGSAPQPITVTLRDHIET MAV_3239|M.avium_104 RFVLTVHHLVMDGWSLPVLLQEIFACYYG------ARLPAPAPYRGFVTW Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VTDRDRGAARQAWEQALAGAEPTALVPRPDGAPVGEHRSVVRRLDSARTA MAV_3239|M.avium_104 LAARDVPAARAAWRAVLDGFDTPTLVAPRGADAPGRRGVASFRMAAETTS Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVGRAARVHGVTVGTVLHGAWGLMLGRLLGRNRVVFGSTVSGRGGDLAGT MAV_3239|M.avium_104 AVSELARRRRTTVNTVLQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ESIVGLLINTIPVPMSWEPHATLASALIDLQDQQSALLDAQQMGLAELAR MAV_3239|M.avium_104 ESMVGLLINTVPVRARAAAATTIADLLDQLQCAHNDTVEHQHLGLNEIHR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LAGVREFFDTMVIVENFPSTSSAEHTDPRAVAFRGFTGTDSPHYPVSFVA MAV_3239|M.avium_104 VTGQDQLFDTLLVYENYP-IDTAALSAADDLTATEFSCHDYNHYPLSLQV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YADDQLTVEIKYDAGVVTPEQAERYAERVERILTAFAETPDLPVSRIDLR MAV_3239|M.avium_104 VPGDELGLRLEFDTDVFDPAAIDTLADRLRRLLAAMPADPDRPLRSLDLL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TNAERQFTAGHASRPGPGRTLG-----ASFAEVAATYPDAVAVSCGDTRL MAV_3239|M.avium_104 DSTEHTRLQRWGNRPALSRPATGPSLPELFTAQVANAPHAVALRCAGRSM Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TYRELDDRAAAVAATLAERGVGAESRVAIALPRSADLIVAVLAVIKAGGT MAV_3239|M.avium_104 TYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YVPIDIGAPAARVQHILADSAPVCLLTDTAERFTGVPH---VILAEAAQN MAV_3239|M.avium_104 YLPIDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVAATGA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PARPQAPTVSPDHAAYVIYTSGSTGVPKGVEVTHRNVAALFAGTTSGLYD MAV_3239|M.avium_104 QPGGPLPPPAPDNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FGPDDVWTMFHSAAFDFSVWELWGPLLHGGRLVVVEHDVARDPERFVDLL MAV_3239|M.avium_104 ---TGVWSQCHSYGFDVSVQEIWGALAGGGRLVVVPESVTSSPDELHALL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ARERVTVLNQTPSAFYPLLEADARLRRQLALRYVIFGGEALDVRRLAPWY MAV_3239|M.avium_104 IAENVTVLSQTPSALAALSPRN--------------LHAALVIGGEPCPA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ANHESHSPRLVNMYGITETCVHVSHRALDTADTGAAGSVIGGPLPGLRIH MAV_3239|M.avium_104 ALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLF Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LLDNNLQPVPAGVVGEMYIAGGQVARGYTGRPGLTATRFVANPFDGAGER MAV_3239|M.avium_104 VLDGWLRPVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGAGAR Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LYRSGDLAMWTDAGELVYLGRSDAQVKVRGYRIELGEVEAALVTLPGVTN MAV_3239|M.avium_104 MYRTGDLVRWDRDGRLHYVARADQQVKIRGHRIELGEIHSALAELDGVEQ Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AAADVRHDDTGRARLIGYVVGDALDIGALRSTLAERLPDYMVPSVLLRLD MAV_3239|M.avium_104 AAVIAREDRPGEKRIVGYLTG-TADPAAIRARLAERLPAYMVPAAVLAIE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VLPLTVNGKLDRAALPDPEPVEQAPAPVAGTGTASLLAGLCTEILGTTVG MAV_3239|M.avium_104 ALPLTPNGKLDARALPAPEYAGGAYRAPSTPTEEIIAGIYTQVLGLHRVG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VEDDFFTAGGDSIIAIQLVNRARREGVRITPQQVFVHRTPAALASVLDTG MAV_3239|M.avium_104 VDDSFFDLGGDSLSAMR--------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SVAAPDATPDEDAGPDLGEVMLTPIVQRLAELGGTVTRFNQSELLRTPAG MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ATVARLETAINAVIARHDALRIRLHRPAPMLWSLETTAAAPVSITRIDAH MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GFDDEQLRTVIATESDAAADRLDPENGVVVVAVWFDRGTDTQGRLLLVVH MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HLAVDGVSWRILLDDLAEAYRQALSGQRVAPAPVTTSLRQYARTVNENAQ MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HSSRLTEFEHWTEVLAPGGELVATADVVTLTVGATRDHEIRLSTEDTAPL MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LTTVPAAANADVTETLVAALHLAVSRWRAARGEAADAPLVLSLERHGRDG MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 WPDDVDLSRTVGWFTSIAPVRLPAPGEDLLNTLKAVKESLRAAPDGGLGF MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GQLRYCNPRTSAVLARLGTPQLLFNYLGRWAADACDDWASAPEVDALRTE MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -----------------VTDTTETRPAGADDEARLALLRRRLSERGLS-- Mvan_3845|M.vanbaalenii_PYR-1 --------------------MTDIDTGALLDERRLELLRRRMQERGLS-- Mflv_2696|M.gilvum_PYR-GCK --------------------MTDTD----LDARRLELLRRRLAGSGLREQ MSMEG_0019|M.smegmatis_MC2_155 PNPDLGTPYLVEVNAICDDTVDGPRLRATLTYADGELDEPSVAELGELWV MAV_3239|M.avium_104 -----------VIAAVNAGLDARLSVRVLFEAPTIAQLAARLGEGGHR-- Mb0104|M.bovis_AF2122/97 -----------MHRVRLSRSQR---------------------------- Rv0101|M.tuberculosis_H37Rv -----------MHRVRLSRSQR---------------------------- MMAR_0256|M.marinum_M ---MTAPEIGCAEAIPLSKSQQ---------------------------- MUL_4858|M.ulcerans_Agy99 ---MTAPEIGCAEAIPLSKSQQ---------------------------- MLBr_01996|M.leprae_Br4923 ---MTAPNTRRVDRVPLSRSQQ---------------------------- MAB_0663|M.abscessus_ATCC_1997 ---MTVVLEPQVDRVPMSRSQQ---------------------------- TH_3141|M.thermoresistible__bu --AQQTTGAAS--EDRLSDGQL---------------------------- Mvan_3845|M.vanbaalenii_PYR-1 --AGTDTAEPAGDTDVLTEGQL---------------------------- Mflv_2696|M.gilvum_PYR-GCK DPAEPVAVAADPARGEFTDGQK---------------------------- MSMEG_0019|M.smegmatis_MC2_155 AALRELGSLATGGDAALTPSDLPLVTLTQEHIDRVTGAVPGNVETIWPLS MAV_3239|M.avium_104 --FAAVVAAERPAVVPLSFAQS---------------------------- :: .: Mb0104|M.bovis_AF2122/97 ---NLYNGVRQDNNPALYLIGKSYRFR-RLELARFLAALHATVLDNPVQL Rv0101|M.tuberculosis_H37Rv ---NLYNGVRQDNNPALYLIGKSYRFR-RLELARFLAALHATVLDNPVQL MMAR_0256|M.marinum_M ---NLYNGVLQDNDPALYLIGKRYRFH-PLALSNFLAALEASVLNNPVQL MUL_4858|M.ulcerans_Agy99 ---NLYNGVLQDNDPALYLIGKRYRFH-PLALSNFLVALEASVLNNPVQL MLBr_01996|M.leprae_Br4923 ---NIYNGMLQDNDPALYFIGKSYRFH-QLELSVFLAALEATILKNPGQL MAB_0663|M.abscessus_ATCC_1997 ---NMYNGAVQASDPGLYLIGKSFRFH-PIELAAFMCALEAAVAANPVQL TH_3141|M.thermoresistible__bu ---RMWFVHQADPSGALLNICLSYRISGPVDLAALRGALDAVARRHPVLR Mvan_3845|M.vanbaalenii_PYR-1 ---RMWFVHNADPSGALLNVCLSYRLSGEIDVARLHDAVGAVARRHRVLR Mflv_2696|M.gilvum_PYR-GCK ---RMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVARRHPVLR MSMEG_0019|M.smegmatis_MC2_155 PLQEGVYLQARYATAAVYIVQNVFDFAEPVDTTALRTAYSAVMARNPVLR MAV_3239|M.avium_104 ---RLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLR . : : : : : * : Mb0104|M.bovis_AF2122/97 CVLEN-----------SGADYPDLVPRLRFGDIVRVG---SADEH----- Rv0101|M.tuberculosis_H37Rv CVLEN-----------SGADYPDLVPRLRFGDIVRVG---SADEH----- MMAR_0256|M.marinum_M CVLQMA---------ATDADYPQLVPRLQFSDLVLVR---SAAQGQPDGP MUL_4858|M.ulcerans_Agy99 CVLQMA---------ATGADYPQLVPRLQFSDLVLVR---SAAQGQPDGP MLBr_01996|M.leprae_Br4923 CVLEAP---------STEGDYPDLVPRLQFGDIVRVR---SDEQPQTDSR MAB_0663|M.abscessus_ATCC_1997 CVLEPG---------VQHDRHPELVQRLQFGDIVSIA---ADEEGLTART TH_3141|M.thermoresistible__bu TTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQARRLRLEV Mvan_3845|M.vanbaalenii_PYR-1 TTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ERARGLRLEV Mflv_2696|M.gilvum_PYR-GCK TTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EHARRLRLEV MSMEG_0019|M.smegmatis_MC2_155 SAF-----WADDLPQPVAAIVADPVCEPRVVDLGGLP---ATQVERRVEE MAV_3239|M.avium_104 TVFA----ATDGTPAQVVLPPDRADIGWQVIDASGWS-------PARVDD . * Mb0104|M.bovis_AF2122/97 ---LQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTI Rv0101|M.tuberculosis_H37Rv ---LQSTWCSGILGKPLVRHTVHTDPNGYVTGLDVHTHHILLDGGATGTI MMAR_0256|M.marinum_M GADLEHTWSSGILDRPLVRYTVSTDEGGNVCGLDVHTHHILLDGGATGII MUL_4858|M.ulcerans_Agy99 GADLEHTWSSGILDRPLLRYTVSTDEGGNVCGLDVHTHHILLDGGATGII MLBr_01996|M.leprae_Br4923 DYDLMHAWSPDILAKPLVRYTVRTDKNGFVARLDVFTHHILVDGGAIRII MAB_0663|M.abscessus_ATCC_1997 ADAVASQWAADLKARPLVRYTVRTGADGRVRGLDIHAHHLLLDGGAIGVI TH_3141|M.thermoresistible__bu LAQREFTAPFDLSVDSPLRITMIRTGADEHI-MLLVAHHIAWDDGSWEVF Mvan_3845|M.vanbaalenii_PYR-1 LAQREFGRPFDLGAESPLRITVIRTAPAEYV-MLLVAHHIAWDDASWEVF Mflv_2696|M.gilvum_PYR-GCK LAQREFGTPFDLATESPLRITVARTAPAEYI-MLLVVHHIAWDDGCWRVF MSMEG_0019|M.smegmatis_MC2_155 ITADDRQQTFDLAAAPLARMTVLRT-PDRDR-LIFSYHFLLLDGWSREQL MAV_3239|M.avium_104 VIRDTARHTFDLAAEIPLRAVLLRCGDEEHL-LVAVVHHIAADGWSLTPL .: * .: : *.: *. . : Mb0104|M.bovis_AF2122/97 EADLARYLTTDPAG----ETPSVGAGLAKLREAHRR-ETAKVEESRGRLS Rv0101|M.tuberculosis_H37Rv EADLARYLTTDPAG----ETPSVGAGLAKLREAHRR-ETAKVEESRGRLS MMAR_0256|M.marinum_M EADLAHFLAASLEPAGVGQMPTLSQGLAKLAAAHLR-ETAKVAEALRRQA MUL_4858|M.ulcerans_Agy99 EADLAHFLAASLEPAGVGEMPTLSQGLAKLAAAHLR-ETTKVAEALRRQA MLBr_01996|M.leprae_Br4923 EENLAHHLDTDNR----LEIPCIRQALDKLAEAHRR-EATKVEESLQRLA MAB_0663|M.abscessus_ATCC_1997 EADLGRNLSSAKE----AKVSRTTGALTRIATAHSR-EIAKADESLQRFG TH_3141|M.thermoresistible__bu FDDLTRAYTGVDLGEELAPQLPPG-------------------PRDPDAD Mvan_3845|M.vanbaalenii_PYR-1 FDDLTGAYVGEKLRPARRPVVAAG-------------------GSD-EDD Mflv_2696|M.gilvum_PYR-GCK FADLTRAYTGAELGPTPAPVVEPP-------------------TSD--ED MSMEG_0019|M.smegmatis_MC2_155 LRELFAEYTAARGGAVAQLPAPTADFTDYLRWL---------ARQDRDVS MAV_3239|M.avium_104 VRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQ :* Mb0104|M.bovis_AF2122/97 AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLS Rv0101|M.tuberculosis_H37Rv AVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLS MMAR_0256|M.marinum_M DAVQRELTAEAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALS MUL_4858|M.ulcerans_Agy99 DAVQRELTAEAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALS MLBr_01996|M.leprae_Br4923 NVVQRELADEVRNGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALS MAB_0663|M.abscessus_ATCC_1997 AAIQRELTDAARRSVPGQHCDGAASGAAKGVLLESVTVSAKAFDAITALA TH_3141|M.thermoresistible__bu LAYWREVLADPPEPLELPGPHGSAVPSGWRSARDSVTLGADTARRVVELA Mvan_3845|M.vanbaalenii_PYR-1 VAYWRAVMADPPEPLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALA Mflv_2696|M.gilvum_PYR-GCK LRFWRSAMTDLPEPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAA MSMEG_0019|M.smegmatis_MC2_155 AREWSEALRDLEAPTLLVPDAVGTDPT--LALRLEFLLSEADTAALTAAA MAV_3239|M.avium_104 LRYWESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLA . : : : Mb0104|M.bovis_AF2122/97 EAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSD--LNVATC Rv0101|M.tuberculosis_H37Rv EAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSD--LNVATC MMAR_0256|M.marinum_M EAQQVPLNVLVAAAAVAVQAGLRQSTESLLVHAVDNRFGDPE--LNVATC MUL_4858|M.ulcerans_Agy99 EAQQVPLNVLVAAAAVAVQAGLWQSTESLLVHAVDNRFGDPE--LNVATC MLBr_01996|M.leprae_Br4923 ETKQVPLNILVATAAVAVDASLRQSTEGLLVHAVDNRFGDPY--LDVATC MAB_0663|M.abscessus_ATCC_1997 EREQVPLNILVAAAAVAVDASLRQSTQTLLIHAVDNRFGEPD--LEVATC TH_3141|M.thermoresistible__bu QETGCTPYAVLLAVFGTLIFRYTHADDFLVATPVLNRDSGAE---QRIGY Mvan_3845|M.vanbaalenii_PYR-1 DEVGATPYAVLLAVFGVLIHRYSHVDDFLVATPVLNRNGDTD---DVIGY Mflv_2696|M.gilvum_PYR-GCK REAGATPYMVMLAAFGALLHRYTHADDVLIASPVLLRGPDSE---DVIGY MSMEG_0019|M.smegmatis_MC2_155 RSAGVTLNALISTALAMVLAYETGRDDVVFGSTVAGRPTDLDGIDSVIGL MAV_3239|M.avium_104 GAHNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALD--DVVGF . :: :. : : . .: * . Mb0104|M.bovis_AF2122/97 LVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAIN Rv0101|M.tuberculosis_H37Rv LVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAIN MMAR_0256|M.marinum_M LVNSVAHALRFRPFASVREVVRDLDRGYVKAVRRRWIREEHYRRMYLAIN MUL_4858|M.ulcerans_Agy99 LVNSVAHALRFRPFASVREVVRDLDRGYVKAVRRRWIREEHYRRMYLAIN MLBr_01996|M.leprae_Br4923 LVNSVAHSIRFPPFASVQDVVRTLDRSYVKAIRLRWLREEYYRRIYLALN MAB_0663|M.abscessus_ATCC_1997 LVNSIAHPVSFPAFASVREVVRSLDRDYVKASRRRWLREEQYRRMYLAIN TH_3141|M.thermoresistible__bu YGNTVAMRLRPNAAMSFRDMLAQSRDTALGAFAHQGINLDRVVRELNPDR Mvan_3845|M.vanbaalenii_PYR-1 FGNTVAMRLRPHPAMTFRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDR Mflv_2696|M.gilvum_PYR-GCK HGNSAVMRLRPQPMQTFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDR MSMEG_0019|M.smegmatis_MC2_155 FLNTVPTRVRLAPHRTVADTMRAVQSDRLRLMDHEYLGLGDIQRAVSTGG MAV_3239|M.avium_104 FVNTLVLRVDVSGDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPAR *: : :. : : : . : . Mb0104|M.bovis_AF2122/97 RTSHVEALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQ Rv0101|M.tuberculosis_H37Rv RTSHVEALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQ MMAR_0256|M.marinum_M RTSHVQALTLNFIRESCAPGLRPFLSEAPVATEIGPIEGTTVACVLDEQR MUL_4858|M.ulcerans_Agy99 RTSHVQALTLNFIRESCAPGLRPFLSEAPVATEIGPIEGTTVACVLDEQR MLBr_01996|M.leprae_Br4923 QTSHIEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEGMTVACVLNEDE MAB_0663|M.abscessus_ATCC_1997 KTAQVEALTFNFIRETCAPALRPFLSAAPRVTDIGPVEGMTVSCVADEDR TH_3141|M.thermoresistible__bu RHGTERMTRVSFGFR--GPDRFGFTPPGVRCERAELRSHLTQLPLGVMIE Mvan_3845|M.vanbaalenii_PYR-1 RHGAERMTRVSFGFR--SRDRFGFTPPGVTCERADLRSHLTHLPLGIMVE Mflv_2696|M.gilvum_PYR-GCK RHGAERMTRVSFGFR--EPDGGGFSPPGVTCRRAELRGQITQLPLGLMVE MSMEG_0019|M.smegmatis_MC2_155 GPLFDSLYVLQNFLD--DDTFTDMEAQYGIVGHDSIDASHYPLTWVASPG MAV_3239|M.avium_104 SLAHHPLVQVMLAWQNIEPTELSLGQVRVIPLPVDTRTARMDLAWSLAER . : Mb0104|M.bovis_AF2122/97 RTLN-------LAIWNRADLPACKTHPKVAERIAAALESMAAMWDRP--- Rv0101|M.tuberculosis_H37Rv RTLN-------LAIWNRADLPACKTHPKVAERIAAALESMAAMWDRP--- MMAR_0256|M.marinum_M HTLN-------LAIWDRADLPERNTGAGVAARIGAALESMAALWDQP--- MUL_4858|M.ulcerans_Agy99 HTLN-------LAIWDRADLPERNTGAGVAARIGAALESMAALWDQP--- MLBr_01996|M.leprae_Br4923 RTLD-------LSIWNRVDLPQGKSCTRVAKRIAAALELMAAAWDQP--- MAB_0663|M.abscessus_ATCC_1997 RTLT-------LSIWHRSDLPKASAHPWVAERIAGALSSMEAMWHMP--- TH_3141|M.thermoresistible__bu FDPDPADPGATVEIEHLVEVIEPALGRQLLRHFVVLLEDALRRPDTPLSR Mvan_3845|M.vanbaalenii_PYR-1 FDPD----EVVVELEHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSG Mflv_2696|M.gilvum_PYR-GCK LHES----GAVVEAEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSR MSMEG_0019|M.smegmatis_MC2_155 RR-------LWMKLEYRPDVVERDRAQGLLDRLRQVLLQVGTGVERPSAA MAV_3239|M.avium_104 WTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTADPGRRLSS :: : : : Mb0104|M.bovis_AF2122/97 ---IAMIVNDWFGIGP---------DGTRCQGD--WPARQPSTPAWFLDS Rv0101|M.tuberculosis_H37Rv ---IAMIVNDWFGIGP---------DGTRCQGD--WPARQPSTPAWFLDS MMAR_0256|M.marinum_M ---IAMTANEWFEVGA---------DGLPCRTEAAGRPRPPSAPAWFVDA MUL_4858|M.ulcerans_Agy99 ---IAMTANEWFEVGA---------DGLPCRTETAGRPRPPSAPAWFVDA MLBr_01996|M.leprae_Br4923 ---IAMIVNEWFGISS---------DGALCLGNEVTQTTRPLAPAWFLDP MAB_0663|M.abscessus_ATCC_1997 ---IAMTVNEWFGIGA---------DGARRRGDDHAPAESTALPAWFVDS TH_3141|M.thermoresistible__bu LRLMDDADLAWLRDVS---RGDRFDTPARTLPDLIESQVRQTPDAVAVVY Mvan_3845|M.vanbaalenii_PYR-1 LQLMGDDDLEWLRAVS---VGPTFDTPPATITDLIEAQVRRSPDGTAVVY Mflv_2696|M.gilvum_PYR-GCK LELMDGDDAEWLRRVS---HGPEFDVPAATIGELIEARTDLTPDTVAVVY MSMEG_0019|M.smegmatis_MC2_155 LTLPLPAEADHKRTRD---AATEHDLPHASVLDLLAERAVQSGDLTALVC MAV_3239|M.avium_104 IDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQVARTPHAVALTA : Mb0104|M.bovis_AF2122/97 ARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACH Rv0101|M.tuberculosis_H37Rv ARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACH MMAR_0256|M.marinum_M APGLRQFLDRRRHVYPWVGWLVCHGVVPGDVLVCTDDDTDKTVDLLLACH MUL_4858|M.ulcerans_Agy99 APGLRQFLDRRRQVYPWVGWLVCHGVAPGDVLVCADDNTDKTVDLLLACH MLBr_01996|M.leprae_Br4923 GGSVHLTVDKRRYVHPWIAWLVRGSVVPGDVLVFTDDNTDKTIDLLIACH MAB_0663|M.abscessus_ATCC_1997 EDAVAEFLQRRRFVEPWIGWLIAAGVSPGDIVVCADDDSDKAIDLLIACH TH_3141|M.thermoresistible__bu EGRHYSYRELNEAANRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVL Mvan_3845|M.vanbaalenii_PYR-1 EGRHYTYREINEAANRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVL Mflv_2696|M.gilvum_PYR-GCK EGRRYTYREINESANRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGII MSMEG_0019|M.smegmatis_MC2_155 GGEFVDYAELLARVNRLAWVLRSRGIGPEDTVALAVPRSIDAVVALFAVL MAV_3239|M.avium_104 NGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAILGVL . * . . :. : . : :. Mb0104|M.bovis_AF2122/97 LAGCGYSVCDTADEISVRTNAITEHGDGILVTVVD-------VAATQLAV Rv0101|M.tuberculosis_H37Rv LAGCGYSVCDTADEISVRTNAITEHGDGILVTVVD-------VAATQLAV MMAR_0256|M.marinum_M LAGCGYSMCESVDDLSLRATTIGEHCEGSSAHPVD-------VAAVRLGA MUL_4858|M.ulcerans_Agy99 LAGCGYSMCESVDDLSLRAKTIGEHCEGISAHPVD-------VAAVRLGA MLBr_01996|M.leprae_Br4923 LAGCGYSVCDTVAEVPLRAKAITDHGGGVSARVID-------VAATQLAV MAB_0663|M.abscessus_ATCC_1997 LAGCGYSVCENSEGLVARSDSIAMQGDDITVHAVD-------IAVT-IPT TH_3141|M.thermoresistible__bu KAGAVYLPIDPTYPDDRLSFILGDCDARLVLR-------------EPVSD Mvan_3845|M.vanbaalenii_PYR-1 KAGAVYVPIDPAYPQDRLEFILGDCDAKVVVR-------------EPVTG Mflv_2696|M.gilvum_PYR-GCK KAGAVYLPVDPSYPQDRMSFVLSDSDPTLVIR-------------EPVAG MSMEG_0019|M.smegmatis_MC2_155 RAGAAYLPLELDYPDERLAVMLGDAEPVRVLVTGATAQRIARVASAPLTV MAV_3239|M.avium_104 KAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCR------LQEYD **. * : : Mb0104|M.bovis_AF2122/97 VGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSL Rv0101|M.tuberculosis_H37Rv VGHDELRKVVDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSL MMAR_0256|M.marinum_M VPDHALRERIDQRLDQVARDPLLATKAAYIMPTSGTTGQPKLVRISHGSL MUL_4858|M.ulcerans_Agy99 VPDHALQERIGQRLDQVARDPLLATKAAYIMPTSGTTGQPKLVRISHGSL MLBr_01996|M.leprae_Br4923 TPDNEQSKLADKLIKQAAQDISLADKTAYIMPTSGSTGQPKLVQVSHGSL MAB_0663|M.abscessus_ATCC_1997 ELDASMRGRVAERREQVAKDGALAEKTAYIMATSGSTGRPKLVPISHGAL TH_3141|M.thermoresistible__bu LDGQPTTDPTDTDR----VRRLLPGNTAYLIYTSGTTGLPKGVPVPHRPV Mvan_3845|M.vanbaalenii_PYR-1 LDGYRADDPGDNDR----RRPVGPYNTAYLIYTSGSTGLPKGVPVPHRPV Mflv_2696|M.gilvum_PYR-GCK LDGHRTDNPTDDVR----VRPLRPENAAYLIYTSGSTGQPKGVPVPHRPV MSMEG_0019|M.smegmatis_MC2_155 LDAPDTCDELARARSDWDGYSPHPDQPAYVIYTSGSTGKPKGVVTPHRGL MAV_3239|M.avium_104 QTVIDVDDPSIREQPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNA . : **:: ***:** ** * .* Mb0104|M.bovis_AF2122/97 AVFCDAISRAYGWGAHD-------TVLQCAPLTSDISVEEIFGGAACGAR Rv0101|M.tuberculosis_H37Rv AVFCDAISRAYGWGAHD-------TVLQCAPLTSDISVEEIFGGAACGAR MMAR_0256|M.marinum_M AAFCAAIGPSYGWNSRD-------TILQCAPLTSDISVEEIFGAAVCGAE MUL_4858|M.ulcerans_Agy99 AAFCAAIGPSYGWNSQD-------TILQCAPLTSDISVEEIFGAAVCGAE MLBr_01996|M.leprae_Br4923 ALFCDAVRNAYGWGAHD-------TILQCAPLTSDISVEEIFGGAICGSK MAB_0663|M.abscessus_ATCC_1997 ALFVRAAGDAYGWCAQD-------RILQCAPLTSDISVEEVFVAASRGVQ TH_3141|M.thermoresistible__bu AEYFVWFKGDYQVDAND-------RLLQVASPSFDVSIAEIFGTLACGAR Mvan_3845|M.vanbaalenii_PYR-1 AEYFVWFKGDYRVDAGD-------RMLQVASPSFDISIAEVFGTLACGAR Mflv_2696|M.gilvum_PYR-GCK AEYFVWFKDEYEISESD-------RLLQVASPSFDVSIGEIFGTLACGGR MSMEG_0019|M.smegmatis_MC2_155 TNMHLNHREAIFAPTIARAHGRRLKIAHTVSFSFDMSWEELLWLIEG-HE MAV_3239|M.avium_104 TQLFASLGAAGLPAAPG------KVWGQCHSLAFDFSVWEIFGALLNGGR : : . : *.* *:: . Mb0104|M.bovis_AF2122/97 LVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRS Rv0101|M.tuberculosis_H37Rv LVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRS MMAR_0256|M.marinum_M LVRSAAMKTGDLGGLARDIHALGPTVVDLPTAVWHLLCEDGDAVDVIGRS MUL_4858|M.ulcerans_Agy99 LVRSAAMKTGDLGGLARDIHALGPTVVDLPTAVWHLLCEDGDAVDVIGRS MLBr_01996|M.leprae_Br4923 LVRSTAMKTGDLAELARDIFVQRATVIDLPTAVWHLLCDHSDAIDEINRS MAB_0663|M.abscessus_ATCC_1997 VIRSAAMKSADLSALVHDIREAGPTLLDLPTAVWHLLCEDAESLALIGAC TH_3141|M.thermoresistible__bu LVIHRPGGLNDIGYLTALLQDEGITAMHFVPSLLGLFLSLPGVNQWRT-- Mvan_3845|M.vanbaalenii_PYR-1 LVIHRPGGLNDIGYLTALLRDEGITAMHFVPSLLGLFLSLPGVNQWRT-- Mflv_2696|M.gilvum_PYR-GCK LVIPKPDGLTDVAYLTELLQREGITAMHFVPSLLGLFLSLPGVNQWRT-- MSMEG_0019|M.smegmatis_MC2_155 VHICDEVLRRDATSLVRYCHDHRIDVINVTPTYAALLFEEGLLEQAGHP- MAV_3239|M.avium_104 VLVVPDDVVRSPEDLCALLIDEHVDVLSQTPSAFDALQRADSARRLNP-- : . * : .: : Mb0104|M.bovis_AF2122/97 RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIV Rv0101|M.tuberculosis_H37Rv RLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIV MMAR_0256|M.marinum_M RLRQIVIGGESIRTSTVDKWVNSPVLAPISLVSSYGPTEATVVATHLPIV MUL_4858|M.ulcerans_Agy99 RLRQIVIGGESIRTSTVDKWVNSPALAPISLVSSYGPTEATVVATHLPIV MLBr_01996|M.leprae_Br4923 CLRQIVIGGEAVRPCAVDKWIDSGASQGISLMSTYGPTETTVVVTYLPIV MAB_0663|M.abscessus_ATCC_1997 GVRQVVVGGEAIRPGAVDQWVKSTDKNGISLISTYGPTETTVVVTHLSIA TH_3141|M.thermoresistible__bu -LQRVPIGGEPLPGEVADKFHA---TFDALLHNFYGPTETVIN-ASRYKV Mvan_3845|M.vanbaalenii_PYR-1 -LQRVPIGGEALPGEVADKFRA---TFDALLHNFYGPTETVIN-ATRFKV Mflv_2696|M.gilvum_PYR-GCK -LERVPIGGEALPGELADRFHA---TFDALLHNFYGPTETIIN-TTRYKV MSMEG_0019|M.smegmatis_MC2_155 -PVLVLLGGEAVSTTVWNRLRD---SERWYGYNLYGPTEYTIN-TLG--- MAV_3239|M.avium_104 --QTVIFGGEALIPHRLGGWLDGH-PARPRLINMYGITETTVHASFREIV : .***.: . . ** ** : : Mb0104|M.bovis_AF2122/97 CDQTTMDGAL---------LRLGRPILPNTVFLAFGEVVIVGDLVADGYL Rv0101|M.tuberculosis_H37Rv CDQTTMDGAL---------LRLGRPILPNTVFLAFGEVVIVGDLVADGYL MMAR_0256|M.marinum_M YDGIAAAAHTR--------LRVGLPMAPNTVFIAFGEVVIAGPLVSDGYL MUL_4858|M.ulcerans_Agy99 YDGIAAAAHTR--------LRVGLPMVPNTVFIAFGEVVIAGPLVSDGYL MLBr_01996|M.leprae_Br4923 CAPMTVESDAR--------LRLGWPIVPNTVFIAFGELVIVGDLVSVGYL MAB_0663|M.abscessus_ATCC_1997 AG----DGVDC--------RRMGVPVVPNTVFVAFGEVVIVGGTVSAGYL TH_3141|M.thermoresistible__bu EGKQGTRIVPIGRPKINTQLHLLDNALQPVPVGVIGEIYIGGTHVAHGYH Mvan_3845|M.vanbaalenii_PYR-1 EGRQGTRIVPIGKPKINTAIHILDDALQPVPVGSIGEIYIGGTHVARGYH Mflv_2696|M.gilvum_PYR-GCK EGTQGSRIVPIGTPKINTTVHLLDDALRPVPVGAIGEIYIGGGHVARGYH MSMEG_0019|M.smegmatis_MC2_155 GGTDDSATPTVGTPIWNTRAHILDNWLRPVPDGVPGELYIAGAGLARGYL MAV_3239|M.avium_104 DGDIDGNVSPIGMPLAHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYL : . **: * * :: ** Mb0104|M.bovis_AF2122/97 GIDGDGFGTVTAADG--SRRRAFATGDRVTVDAEGFPVFSGRKDAVVKIS Rv0101|M.tuberculosis_H37Rv GIDGDGFGTVTAADG--SRRRAFATGDRVTVDAEGFPVFSGRKDAVVKIS MMAR_0256|M.marinum_M GIDDSSFGAVAPGDG--SQLRAFATADRVTIDEEGFPVFAGRKDTIVKVA MUL_4858|M.ulcerans_Agy99 GIDESSFGAVAPGDG--SQLRAFATADRVTIDEEGFPVFAGRKDTVVKVA MLBr_01996|M.leprae_Br4923 GIDSRNFGTVTTTDG--SCRRAFATADCVILDDEGFPVFSGRKDAVVKIS MAB_0663|M.abscessus_ATCC_1997 GTPSESFGVVRTGEG--KSRPAFATADRVVFDEDGLPSFAGRRDAIVKIS TH_3141|M.thermoresistible__bu RRPGLTAERFVADPF-NPGGRLYRSGDLARRNADGDIEFVGRADEQVKIR Mvan_3845|M.vanbaalenii_PYR-1 HRPGLTAERFVADPF-TPGARMYRSGDLARRNADGDIEFVGRADEQVKIR Mflv_2696|M.gilvum_PYR-GCK RRPALTAERFVADPF-TVGGRLYRSGDLARRNADGDLEFVGRADDQVKIR MSMEG_0019|M.smegmatis_MC2_155 GQPGLTASRFVANPF-EPG-RMYRTGDLVVRRADDNIDFLGRTDDQVKIR MAV_3239|M.avium_104 GRPGLTASRFVACPFGGAGERMYRTGDLARWGTDGQLHYLGRADQQVKIR . . : :.* . :. : ** * **: Mb0104|M.bovis_AF2122/97 GKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQD---- Rv0101|M.tuberculosis_H37Rv GKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQD---- MMAR_0256|M.marinum_M GKRVDTAAVARRISADPTVCDVAVEPHDGRLGVWFETERTREAAED---- MUL_4858|M.ulcerans_Agy99 GKRVDTAAVARRISADPTVCDVAVEPHDGRLGVWFETERTREAAED---- MLBr_01996|M.leprae_Br4923 GKRVDTAELIRRISTDPNVSDVAVEVYNGRLGVWFETKLTREGVDD---- MAB_0663|M.abscessus_ATCC_1997 GKRIDTAAIIARVAEDRAVADVDVAVHNGALVVWFQ---TRHGVDD---- TH_3141|M.thermoresistible__bu GFRIELGDVAAAISVDPSVGQAVVVATDLPNVGRSLVGYLTPVSGESTDS Mvan_3845|M.vanbaalenii_PYR-1 GFRIELGDVAAAITVDPSVGQAVVVVSDLPNLGKSLVAYLTPADG---AG Mflv_2696|M.gilvum_PYR-GCK GFRIELGEVAAAISVDPSVGQAVVLGQDLPGLGMSLVGYVTPAAG---ED MSMEG_0019|M.smegmatis_MC2_155 GYRVELGDIEAALVSHPGVSQAAVIARPDTAGSSRLVAYVVPTTE---NP MAV_3239|M.avium_104 GYRIELGEIQSALAELDGVEQATVIAREDRPGDKRLVGYVTGTADP---- * *:: . : : * :. * Mb0104|M.bovis_AF2122/97 --AAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSA Rv0101|M.tuberculosis_H37Rv --AAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSA MMAR_0256|M.marinum_M --GATAGRIGLTLASLGVPAFFVVAVPSIPRKPNGKVDGARLHTLPQLAD MUL_4858|M.ulcerans_Agy99 --GATAGRIGLALASLGVPAFFVVAVPSIPRKPNGKVDGARLHTLPQLAD MLBr_01996|M.leprae_Br4923 --AAAATRSRLILASLGVSSFFVVGVPCIPRKPNGKIDRDNLLVMPQLVD MAB_0663|M.abscessus_ATCC_1997 --NESAVSIRRLLVELGVSSFVVVAVPSIPRKPNGKVDKDGLRALPQFVE TH_3141|M.thermoresistible__bu VAVERIRARVAAALPEYMVPAAYVVLDEIPITTHGKIDRAALPEPQ-IAS Mvan_3845|M.vanbaalenii_PYR-1 VDVDRIRTRVAAALPEYMTPAAYVVVDEIPITAHGKIDRAALPEPE-IAP Mflv_2696|M.gilvum_PYR-GCK VDLARVRERVAAALPDYMTPAGYVVLDEIPITAHGKIDRAALPLPE-ITT MSMEG_0019|M.smegmatis_MC2_155 DVLDDLRMHLTATLPAYMVPTAMATLTEIPLTDNGKLDTRALPDVAPIGR MAV_3239|M.avium_104 ---AQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKLDTGALPAPD-YHG : . . : :* . :**:* * Mb0104|M.bovis_AF2122/97 AGLNTAETGQRAAGLSQIWSRQLG----RAIGPDSSLLGEGIGSLDLIRI Rv0101|M.tuberculosis_H37Rv AGLNTAETGQRAAGLSQIWSRQLG----RAIGPDSSLLGEGIGSLDLIRI MMAR_0256|M.marinum_M AVPSDAEAGESAAGLARVWSRHLG----RPLAADSSLLGAGIGSLDLIRI MUL_4858|M.ulcerans_Agy99 AVPRDAEAGESAAGLARVWSCHLG----RPLAADSSLLGAGIGSLDLIRI MLBr_01996|M.leprae_Br4923 SVQNYAGSGEGAAGLAEIWSRHLG----RAILPDSSLLDEGIGSVDLIRI MAB_0663|M.abscessus_ATCC_1997 AVPDEAKAGELAAGLARIWSELLG----RRIGAESSLLAEGIGSLDLIRI TH_3141|M.thermoresistible__bu MIEYREPATDTEREVARLFGDLLGR--SERIGADDSFFDLGGHSLLATKL Mvan_3845|M.vanbaalenii_PYR-1 TTEFREPAAGTEAHLAQLFAELLG---HEKVGADDSFFDLGGHSLLATKL Mflv_2696|M.gilvum_PYR-GCK ATDYREPQTETEQHLAQLFSELLG---VARVGVDDSFFELGGHSLLATKL MSMEG_0019|M.smegmatis_MC2_155 HGAGRAPQGAVEATLCSVFAEVLGLDGPDGLSVDDDFFDLGGHSLLTIRL MAV_3239|M.avium_104 ADQYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAMRL :. ::. *. : :..:: * *: :: Mb0104|M.bovis_AF2122/97 LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR Rv0101|M.tuberculosis_H37Rv LPETRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR MMAR_0256|M.marinum_M LPDTRRYLGRHLSVLELISADTAANLVCDLGSNPAAPATD---------- MUL_4858|M.ulcerans_Agy99 LPDTRRYLGRHLSVLELISADTAANLVCDLGSNPAAPATD---------- MLBr_01996|M.leprae_Br4923 LPDTRRHLGRHLSLLDLISADNAANLT-------AAQTAN---------- MAB_0663|M.abscessus_ATCC_1997 LPASRRHLGRELSVLDLISADSAAYLA-------AAGAAV---------- TH_3141|M.thermoresistible__bu VAAVRSAFGVDIGVQDVFELGTVARLAGRIDELRSGSGGPLRPRLTPQHF Mvan_3845|M.vanbaalenii_PYR-1 VAELRAGFGVDVEVRDIFENATIARLAAHLDTMGRATIGTRRPRLVAAPL Mflv_2696|M.gilvum_PYR-GCK VSAVRSRCGVDMEIREIFELGTVARLAERVDELAAGGSAPLRPRLLAVPH MSMEG_0019|M.smegmatis_MC2_155 ISRIRSELGAELTLGDVFNSRTVAALARHVTADEGDN---RRPRLVAGPR MAV_3239|M.avium_104 VAEVNSRLDVHLGVRALFEAPTIRRLAARLGADGSAR-----APLVAAER :. . . : : :: . *. Mb0104|M.bovis_AF2122/97 PAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADV Rv0101|M.tuberculosis_H37Rv PAAIPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADV MMAR_0256|M.marinum_M -----------------------------------GWLDAETAAAIERDL MUL_4858|M.ulcerans_Agy99 -----------------------------------GWLDAETAAAIERDL MLBr_01996|M.leprae_Br4923 -----------------------------------VWMDVGTAAEIERDL MAB_0663|M.abscessus_ATCC_1997 -----------------------------------DELARRDIADIATDL TH_3141|M.thermoresistible__bu DGPAPLSSSQLRSWFAYRVDGPSVVNNIPFAARLHGPVDVDALEAAIGDV Mvan_3845|M.vanbaalenii_PYR-1 DGPAPLSSSQLRSWFGYRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDV Mflv_2696|M.gilvum_PYR-GCK DGPAPMSAAQLRQWFQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDV MSMEG_0019|M.smegmatis_MC2_155 PQHIPASPAQRRMLMLDRLGETGSAYNYPLVFRVRGALDVDALRDALTAV MAV_3239|M.avium_104 PAVVPLSFAQSRLWFIGQLHGPSPVHNMAIALQLHGRLDAAAFGAALADV : Mb0104|M.bovis_AF2122/97 VGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIE Rv0101|M.tuberculosis_H37Rv VGRHESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIE MMAR_0256|M.marinum_M VSLGSQC----------------------------TPQPLGAKPPPHDRA MUL_4858|M.ulcerans_Agy99 VSLGSQC----------------------------TPQPLGADPPPHDRA MLBr_01996|M.leprae_Br4923 ASLCRQR----------------------------NATEFSVKQTRNSHQ MAB_0663|M.abscessus_ATCC_1997 ERMTHSR----------------------------AFAALCGN-ASGAVD TH_3141|M.thermoresistible__bu IARHEILRTVYREIDGVPYQIVLPTEP----VPVRRADGQGEQWLRAELD Mvan_3845|M.vanbaalenii_PYR-1 VERHAILRTTYREIDGVPYQIVNPISD----VPVRRARGEGEQWLQAELD Mflv_2696|M.gilvum_PYR-GCK VNRHESLRTTFCEIDGVPYQLVNAPDPG---FPVRRDSGPDDAWLVGALD MSMEG_0019|M.smegmatis_MC2_155 VDRHEALRTVFDDRDGVYHQRILPRGTQ---PPLHVSDCP-EHELATRAD MAV_3239|M.avium_104 VGRHESLRTLFPAHEGIPQQLVIEVDEADIGWQVIDASGWSPARLDDVIR Mb0104|M.bovis_AF2122/97 EAARHSFDLATEIPLRTWLFRIADD----------------------EHV Rv0101|M.tuberculosis_H37Rv EAARHSFDLATEIPLRTWLFRIADD----------------------EHV MMAR_0256|M.marinum_M AAP----------------------------------------------I MUL_4858|M.ulcerans_Agy99 AAP----------------------------------------------I MLBr_01996|M.leprae_Br4923 KQA----------------------------------------------I MAB_0663|M.abscessus_ATCC_1997 DGP----------------------------------------------I TH_3141|M.thermoresistible__bu AERRHVFDLENERPIRPAILSLRPDAGSPD----SPAGD--------VHV Mvan_3845|M.vanbaalenii_PYR-1 RERKHTFDLEEDWPIRAAVFTVGAVSPASDGGAVSPASDGGAVDPASDHV Mflv_2696|M.gilvum_PYR-GCK DERRRVFDLENQWPIRVAVLSIPG-----------------------EHA MSMEG_0019|M.smegmatis_MC2_155 ALVEHRFDLTGEIPLRVDVLRSGPE----------------------DHT MAV_3239|M.avium_104 DTARHTFDLAAEIPLRAVLLRCGDE----------------------EHL Mb0104|M.bovis_AF2122/97 LVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLW Rv0101|M.tuberculosis_H37Rv LVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLW MMAR_0256|M.marinum_M VVLGASGIVGTGFARAVLERKQAGLACPEIV------------------- MUL_4858|M.ulcerans_Agy99 VVLGASGIVGTGFARAVLQRKQAGLACPEIV------------------- MLBr_01996|M.leprae_Br4923 VVLGASGILGTGFAQAVLDLRQSGVLCPEVV------------------- MAB_0663|M.abscessus_ATCC_1997 VVLGASGIVGTGFARATLELKREGRLRPDVV------------------- TH_3141|M.thermoresistible__bu LSLVMHHIAGDHWSATVLFTDLLTAYRARTAGQEPAWAPLPVQYADFGAW Mvan_3845|M.vanbaalenii_PYR-1 LSVVIHHIAGDHWSGGVLFTDLVAAYRARKAGERPTWAPLPVQYTDYGAW Mflv_2696|M.gilvum_PYR-GCK LSVVVHHIAADHWSGGVLFTELLTAYRARRAGEAPTWAPLPVQYADYAAW MSMEG_0019|M.smegmatis_MC2_155 VVMLLHHIAIDEWSDAVFLADLDAAYAAHRAGTAAPLPEPVVQYADHTLW MAV_3239|M.avium_104 LVAVVHHIAADGWSLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLW : * :: : . . Mb0104|M.bovis_AF2122/97 QREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGA Rv0101|M.tuberculosis_H37Rv QREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGA MMAR_0256|M.marinum_M ----------------------------LASRSKPPEHGPWSALRG---- MUL_4858|M.ulcerans_Agy99 ----------------------------LASRSKPPEHGPWSALRD---- MLBr_01996|M.leprae_Br4923 ----------------------------LATRARLPEGDPWTALQG---- MAB_0663|M.abscessus_ATCC_1997 ----------------------------LVTRSPLPDDGPWPGLTG---- TH_3141|M.thermoresistible__bu ESELLAEETG---IAGPQREYWTRQLAGLPEETGLRPDFPRPPVPSGL-- Mvan_3845|M.vanbaalenii_PYR-1 QAELLSDDTG---IAGPQREYWIRQLADAPVESGLPLEFSRPRLPSGK-- Mflv_2696|M.gilvum_PYR-GCK QSALLADDSG---IVAAQRRYWTQQLEGLSAETGLQPDLVRPSVPSGA-- MSMEG_0019|M.smegmatis_MC2_155 QRDVLAQLG------DRQREFWRTALAGAPDELALPADRPRPARPTGA-- MAV_3239|M.avium_104 QRAQFGDLDDPHSLIAGQLRYWESALAGMPERLELPTDRPYPVVADFR-- . . Mb0104|M.bovis_AF2122/97 SLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGF Rv0101|M.tuberculosis_H37Rv SLVVDWPASVQQQVRRIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGF MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 PIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYEN Rv0101|M.tuberculosis_H37Rv PIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSFAELLGQVRARSLAAYEN MMAR_0256|M.marinum_M ------------------------------------LEGIRIEQLGAT-- MUL_4858|M.ulcerans_Agy99 ------------------------------------LEGIRIEQLGAA-- MLBr_01996|M.leprae_Br4923 ------------------------------------VDGVRIERISFE-- MAB_0663|M.abscessus_ATCC_1997 ------------------------------------VGGVRVLHAGPE-- TH_3141|M.thermoresistible__bu ------------------------------------AEAVEFTIDAAVRE Mvan_3845|M.vanbaalenii_PYR-1 ------------------------------------GDAVEFTIDGQVRR Mflv_2696|M.gilvum_PYR-GCK ------------------------------------ADAVEFTLDAAIRE MSMEG_0019|M.smegmatis_MC2_155 ------------------------------------GGTLDVEITAETAS MAV_3239|M.avium_104 ------------------------------------GASVAVEWPAQLQQ : . Mb0104|M.bovis_AF2122/97 QDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPI Rv0101|M.tuberculosis_H37Rv QDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDNPVGQLNLGDLQATPMPI MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu KLAGLCRDLG---------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 QITELCRELG---------------------------------------- Mflv_2696|M.gilvum_PYR-GCK KLVTLSREVG---------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ALRRLAADKQ---------------------------------------- MAV_3239|M.avium_104 QISRLAGAHN---------------------------------------- Mb0104|M.bovis_AF2122/97 DTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLR Rv0101|M.tuberculosis_H37Rv DTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLR MMAR_0256|M.marinum_M ------------------------------------LGAADLDALIC--- MUL_4858|M.ulcerans_Agy99 ------------------------------------LDAADLDALIR--- MLBr_01996|M.leprae_Br4923 ------------------------------------NGPGELEALIR--- MAB_0663|M.abscessus_ATCC_1997 ------------------------------------FNPGAVDELIR--- TH_3141|M.thermoresistible__bu -------------------------------ITEFMALQAAVAVVLHKAG Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------ITEFMLLQAAVAVTLAKVG Mflv_2696|M.gilvum_PYR-GCK -------------------------------ATEFMLLQAAVAVTLYKAG MSMEG_0019|M.smegmatis_MC2_155 -------------------------------VSMLMVLHAAVAVLIHRLG MAV_3239|M.avium_104 -------------------------------ATSFMVVQAALAVLLAKVS : : Mb0104|M.bovis_AF2122/97 KVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQM Rv0101|M.tuberculosis_H37Rv KVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQM MMAR_0256|M.marinum_M --------------------DTGARSLINCIGNTNVLVP----------- MUL_4858|M.ulcerans_Agy99 --------------------DTGARSLINCIGNTNVLVP----------- MLBr_01996|M.leprae_Br4923 --------------------DTDAGTLVNGVGNTNMLVP----------- MAB_0663|M.abscessus_ATCC_1997 --------------------VTGARTLVNCIGNTNVLAP----------- TH_3141|M.thermoresistible__bu SGSDIPLG-----TPVAGRSEPELDQLVGFFINILVLRNDLSGNPS---- Mvan_3845|M.vanbaalenii_PYR-1 GGLDIPLG-----TPVAGRSEAELEQLVGFFVNFVVLRNDLRGNPT---- Mflv_2696|M.gilvum_PYR-GCK EGPDIPLG-----TPVAGRTESELDQLIGFFINILVLRNDLRDNPS---- MSMEG_0019|M.smegmatis_MC2_155 AGDDIVVG-----TPVAGRDDAALDDVVGLFVNTVVLRADLAGNPT---- MAV_3239|M.avium_104 ASSDVAVG-----FPIAGRRDPALDDVVGFFVNTLVLRVDVSGDPT---- :. * :* Mb0104|M.bovis_AF2122/97 LAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAL Rv0101|M.tuberculosis_H37Rv LAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVAL MMAR_0256|M.marinum_M ----------------------YRGLRAAN--------------VELVST MUL_4858|M.ulcerans_Agy99 ----------------------YRGLRAAN--------------VELVST MLBr_01996|M.leprae_Br4923 ----------------------YRELRLAN--------------VELVSA MAB_0663|M.abscessus_ATCC_1997 ----------------------YRDIRDAN--------------VEWVSA TH_3141|M.thermoresistible__bu ------------------LREVCRRAREMALAAYAHQDLPFDQVVDAVSP Mvan_3845|M.vanbaalenii_PYR-1 ------------------LREVLIRAREMALSAYSNQDVPFEQVVEAVNP Mflv_2696|M.gilvum_PYR-GCK ------------------LRDVGFRSREMALAAYAHQDLPFDQVVDAVSP MSMEG_0019|M.smegmatis_MC2_155 ------------------FTELLDRVRTADLAAFAHQDLPFDHLVEELNP MAV_3239|M.avium_104 ------------------VAELLARVRQRSLAAYEHQDVPFEVLVERLNP : : Mb0104|M.bovis_AF2122/97 LFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTA Rv0101|M.tuberculosis_H37Rv LFERCAPAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTA MMAR_0256|M.marinum_M VAQVCAQRDVRLVHLS------------------TFVISADVTAPRVTDP MUL_4858|M.ulcerans_Agy99 VAQVCAQRDVRLVHLS------------------TFVISADVTAPRVTDP MLBr_01996|M.leprae_Br4923 IVDICASYSTRLVHLS------------------SFVVNADVTVPQVTDP MAB_0663|M.abscessus_ATCC_1997 VTRACTSGGVRLIHMS------------------TFVVNADAVAAQVTDP TH_3141|M.thermoresistible__bu VRTLARNPLFSVVVHVREQLPENRVIDHGPDGDTTVTVLEPPFDAAHADL Mvan_3845|M.vanbaalenii_PYR-1 PRTLARNPLFQVVVHVREQLPQRQMIDT----DTEFTALEPTFDIAQADL Mflv_2696|M.gilvum_PYR-GCK VRSLSRNPLFGVVVHVREELPQDRVIATGSDGETTFTALEPTFDMAHADL MSMEG_0019|M.smegmatis_MC2_155 PRVAGRNPLFNLFVGYHLRSGTDSDMFG-----LPTEWTEPAVSAAMFDL MAV_3239|M.avium_104 ARSLAHHPLVQVMLAWQNIEPTELSLGQVRVIPLPVDTRTARMDLAWS-L :. Mb0104|M.bovis_AF2122/97 GLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPK Rv0101|M.tuberculosis_H37Rv GLRSRLAGHDLPIIDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPK MMAR_0256|M.marinum_M RM-----------------------SPYPYAASKSLAELIVAA----SSP MUL_4858|M.ulcerans_Agy99 RM-----------------------SPYPYAASKSLAELIVAA----SSP MLBr_01996|M.leprae_Br4923 RE-----------------------TPYPYAASKSLAELVVAG----SPS MAB_0663|M.abscessus_ATCC_1997 RE-----------------------AVYPYAASKALAELIVAA----APG TH_3141|M.thermoresistible__bu SLNFFAAE------------DGGGYRGHVIYRPELYSRDTAQRFADWLGR Mvan_3845|M.vanbaalenii_PYR-1 SLNFLA--------------DGTGYRGYLIYRPELYARRTIERLGRWLPR Mflv_2696|M.gilvum_PYR-GCK SVNFFAG--------------GNGYRGHVIYRTELYTRATAERFAGWLSA MSMEG_0019|M.smegmatis_MC2_155 GFTLVDHG------------GDESASITAEYAADLFDASTVHTLARRLVA MAV_3239|M.avium_104 AERWTPDG------------SPAGIGGAVEFRTDVFDTATVEALTQRLRR . Mb0104|M.bovis_AF2122/97 GVGITHRNVTRLFASLPARLSAAQVWSQCHSY------------------ Rv0101|M.tuberculosis_H37Rv GVGITHRNVTRLFASLPARLSAAQVWSQCHSY------------------ MMAR_0256|M.marinum_M ALDFTIVRLPRVLG------EDYQLRESAD-------------------- MUL_4858|M.ulcerans_Agy99 VLDFTIVRLPRVLG------EDYQLRESAD-------------------- MLBr_01996|M.leprae_Br4923 ALDFTIVRLPRVLG------EDYQLRNSSD-------------------- MAB_0663|M.abscessus_ATCC_1997 ELDFTLVRLPRVLG------EAGQLGRSAD-------------------- TH_3141|M.thermoresistible__bu VVTAFAERPDITLRELEIGAPGERRRILEEW------------------- Mvan_3845|M.vanbaalenii_PYR-1 VVAAFVDTPDRALGDVDIVSAEERQRVSQEW------------------- Mflv_2696|M.gilvum_PYR-GCK VITAFADDPERHVDDVVIAEPVRP-------------------------- MSMEG_0019|M.smegmatis_MC2_155 LLDHVVADAETRIGALDLLAPGEHDTLVVEHN---ATEHPLEPITLGALV MAV_3239|M.avium_104 VLAAMTADPGRRLSSIDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVF : . Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SRQATSTPHATALRYEESELSYRDLDGWSDRLAAHLSARGAAPGTVVGVS MAV_3239|M.avium_104 AAHVARTPHAVAVTCGRRSWTYRELDSSANRLAHLLIHHGAGPGDCVALL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LPRSVELVVALVAVAKSGAAFLPLDPEYPRERLEYMVSDARPITVLDDPD MAV_3239|M.avium_104 LERSAEAVAAILGVLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTE Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVRRSRGEPDGELPRIDPAAWAYVLYTSGSTGRPKGVAVAHAGIVNRIAC MAV_3239|M.avium_104 FHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAPDNIAYLIYTSGTTGVPK Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LQHAYPLGTDDRMLVKTPISFDTSVWEVF------------WPLSVGATL MAV_3239|M.avium_104 GVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGALLN Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VVARPGGHREPAYLAAMIAEQCVTAVDFVPSMLEVFLDEVAGTCASLTRV MAV_3239|M.avium_104 GGRVLVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGLESTTL Mb0104|M.bovis_AF2122/97 -----------GFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVA Rv0101|M.tuberculosis_H37Rv -----------GFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVA MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVGGEALTTELAARFAEAFPGVPLHNLYGPTEAAVDVLGWTADGGPVALG MAV_3239|M.avium_104 AVAGEACPVEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIG Mb0104|M.bovis_AF2122/97 EHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNA Rv0101|M.tuberculosis_H37Rv EHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNA MMAR_0256|M.marinum_M ---ILVSVVDACMALRAFPTLTLTEEVTTGRAAAQAILG----------- MUL_4858|M.ulcerans_Agy99 ---ILVSVVDACMALRSFPTLTLTEEVTTGRAAAQAILG----------- MLBr_01996|M.leprae_Br4923 ---ILLSIVDACIALRAYPSATVTEEVTTGRAAAKAILG----------- MAB_0663|M.abscessus_ATCC_1997 ---ILVSIVDACMALHAFPSVRLIEEVTTGASAARAILG----------- TH_3141|M.thermoresistible__bu --G-GGTVYVLDETLQPVPVGVVGDVYTAGPALAAAHWTRAGVTA----- Mvan_3845|M.vanbaalenii_PYR-1 --STGARVQVLDADLAPAPVGVFGDLYLSG-------------------- Mflv_2696|M.gilvum_PYR-GCK --GDGAEAVLLDGAGHPVPVGVVADVHYAGAPDRRGDRARWTEDGRLQYV MSMEG_0019|M.smegmatis_MC2_155 VPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQLADGYLHRGALTAARFVA MAV_3239|M.avium_104 APVPGTALRVLDAHLRPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVA . :* Mb0104|M.bovis_AF2122/97 YGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAG Rv0101|M.tuberculosis_H37Rv YGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAG MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK ERVD---------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SPFD---------------------------------------------- MAV_3239|M.avium_104 CPFGG--------------------------------------------- Mb0104|M.bovis_AF2122/97 ELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQ Rv0101|M.tuberculosis_H37Rv ELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQ MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 LEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRL Rv0101|M.tuberculosis_H37Rv LEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRL MMAR_0256|M.marinum_M ----------------------LLPQFSGAAGLGHGITVVRG---AAVQY MUL_4858|M.ulcerans_Agy99 ----------------------LLPQFSGAAGLGHGITVVRG---AAVQY MLBr_01996|M.leprae_Br4923 ----------------------VVSALARSGQLGSGISVVRG---EAVAY MAB_0663|M.abscessus_ATCC_1997 ----------------------VAAAPS---PLGRGVNVVRG---MPVSY TH_3141|M.thermoresistible__bu --------------TRLVADPVGNRPGARLYRTGDRARWI--------AD Mvan_3845|M.vanbaalenii_PYR-1 ------------------------GPFAQRHRTGDRARWD--------DD Mflv_2696|M.gilvum_PYR-GCK ----------HDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYVVPAEPVD MSMEG_0019|M.smegmatis_MC2_155 ----------QGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVRIEPG MAV_3239|M.avium_104 ----------AGERMYRTGDLVRWGADGQLQYLGRADEQVKIRGYRIELG * Mb0104|M.bovis_AF2122/97 VGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH Rv0101|M.tuberculosis_H37Rv VGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDH MMAR_0256|M.marinum_M RELLSGYALDEIDAAEWKHRLDQ--------------------------- MUL_4858|M.ulcerans_Agy99 RELLSGYALDEIDAAEWKHRLDQ--------------------------- MLBr_01996|M.leprae_Br4923 ADFLSEFASDELNMAEWKYRLDQ--------------------------- MAB_0663|M.abscessus_ATCC_1997 TDFLGGFGIEGLELREWKRLLDR--------------------------- TH_3141|M.thermoresistible__bu GVLEFVDAQP-PTIPAVRP------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 GRLEIAARAPGATVVEVAP------------------------------- Mflv_2696|M.gilvum_PYR-GCK DPASFAETVRAAVAPESAPTSITVLDALPATRRALPA------------- MSMEG_0019|M.smegmatis_MC2_155 EIETVLATHPAVSSVRVIARGGRLMAYYVPAGVEASAGELRDELREHAAA MAV_3239|M.avium_104 EIQSALAALDGVDQAAVIAREDRPGDKRLVGYVTGTADLAQLRTALAERL Mb0104|M.bovis_AF2122/97 RAL--------------------------------PAPEYGDTNGYRAPA Rv0101|M.tuberculosis_H37Rv RAL--------------------------------PAPEYGDTNGYRAPA MMAR_0256|M.marinum_M -------------------------------------SDWARRN------ MUL_4858|M.ulcerans_Agy99 -------------------------------------SDWARRN------ MLBr_01996|M.leprae_Br4923 -------------------------------------SDWAKRN------ MAB_0663|M.abscessus_ATCC_1997 -------------------------------------SAWAKRN------ TH_3141|M.thermoresistible__bu -----------------------------------DSGQRPGGPPATDTE Mvan_3845|M.vanbaalenii_PYR-1 -----------------------------------PAVEFE--EPRTDSE Mflv_2696|M.gilvum_PYR-GCK -----------------------------------PRVGGPSEPARTDTE MSMEG_0019|M.smegmatis_MC2_155 ALPSHMVPSGFVALTEFPLTPSGKLDRRALPEFAGATAGVPGRAPTTERQ MAV_3239|M.avium_104 PG---YMVPAAVLMLDALPLTPSGKLDTGALPAPDYQGPEGYLAPAGAVE Mb0104|M.bovis_AF2122/97 GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNAD Rv0101|M.tuberculosis_H37Rv GPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAINTTLNAD MMAR_0256|M.marinum_M ----------------PQRWSVVDAWVSLG------MRLGARSYSQYLAG MUL_4858|M.ulcerans_Agy99 ----------------PQRWSVVDAWVSLG------MRLGARSYSQYLAG MLBr_01996|M.leprae_Br4923 ----------------PRRWSVIDAWFTLG------MMFEMRSY----AE MAB_0663|M.abscessus_ATCC_1997 ----------------PRRWSVIDAWAGLG------MRLGSRTYGDYLAG TH_3141|M.thermoresistible__bu RALATLLAEVLDTEVTG----RDDDFFSLGGDSILAVQLAARAR-DTGLK Mvan_3845|M.vanbaalenii_PYR-1 RALAALLSELLATEEVG----RHDDFFGLGGDSVLAVQLAARAR-DTGLD Mflv_2696|M.gilvum_PYR-GCK KALVGMLADVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAK-QAGLR MSMEG_0019|M.smegmatis_MC2_155 HRLCELFSDVLGLEVTG----IDDDFFVLGGHSLLLVRLAAALRREFSVD MAV_3239|M.avium_104 EILAWLYAQVLGLPRRVG---VQESFFDLGGDSLSAMRLVAAIYNALDIH : : ** : . Mb0104|M.bovis_AF2122/97 LPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLD Rv0101|M.tuberculosis_H37Rv LPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDNPTEVHASDLTLD MMAR_0256|M.marinum_M YPSIPLQVGT---------------------------------------- MUL_4858|M.ulcerans_Agy99 YPSIPLQVGT---------------------------------------- MLBr_01996|M.leprae_Br4923 YPTMALGVES---------------------------------------- MAB_0663|M.abscessus_ATCC_1997 HRTIPLETAH---------------------------------------- TH_3141|M.thermoresistible__bu LTARMVFEHP---------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 LTARMVFEHP---------------------------------------- Mflv_2696|M.gilvum_PYR-GCK LSARMVFEHP---------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VPVADLMVSP---------------------------------------- MAV_3239|M.avium_104 LPVRAVFEAP---------------------------------------- : Mb0104|M.bovis_AF2122/97 RFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDG- Rv0101|M.tuberculosis_H37Rv RFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLDVDG- MMAR_0256|M.marinum_M ----------VAEIAAPPTALRALLEQGCAQPPRPALA------------ MUL_4858|M.ulcerans_Agy99 ----------VAEIAAPPTALRALLEQGCAQPPRPALA------------ MLBr_01996|M.leprae_Br4923 ----------VAELAAPPESIRALLAHGCSQPLKYTGR------------ MAB_0663|M.abscessus_ATCC_1997 ----------IAELFAVPESIRDLLTQGCSR------------------- TH_3141|M.thermoresistible__bu ---------TLHELAAAVEAR----------------------------- Mvan_3845|M.vanbaalenii_PYR-1 ---------RLAELAAALDS------------------------------ Mflv_2696|M.gilvum_PYR-GCK ---------VVHDLAVALDT------------------------------ MSMEG_0019|M.smegmatis_MC2_155 ---------TVADIDQRLDAAGSSVD------------------------ MAV_3239|M.avium_104 ---------SVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDLTL .: Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3239|M.avium_104 DKFIDAATLSAAPALPGPGAEVRTVLLTGATGFLGRYLVLQWLERLELAD Mb0104|M.bovis_AF2122/97 -RLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKS Rv0101|M.tuberculosis_H37Rv -RLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKS MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------EAVEARETAEAGGAEAGGAESGGGADGAERGAAAGDSGNGAAS Mvan_3845|M.vanbaalenii_PYR-1 ----------------------------GAGAAAEQP----------DTH Mflv_2696|M.gilvum_PYR-GCK -------------------------------AKTPEVA---------DVR MSMEG_0019|M.smegmatis_MC2_155 ----SLAPVLPFRASGTDAPLFCVHPASGLSWQFAGLKRHLPRQIPIYGL MAV_3239|M.avium_104 GKLICLVRAASDDDARRRLERTFDSGDPALLRYFHELAADHLEVIAGDKG Mb0104|M.bovis_AF2122/97 EPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAG-TAELIR Rv0101|M.tuberculosis_H37Rv EPDLGLDQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAG-TAELIR MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu HAPMSTSGLSAEQLSALTASWNPAGEDAP--------------------- Mvan_3845|M.vanbaalenii_PYR-1 HAPMSVSGLSEDELAALTASWG-TGE------------------------ Mflv_2696|M.gilvum_PYR-GCK HDPMSASGLTPEELAMVATSWAAEQDGSP--------------------- MSMEG_0019|M.smegmatis_MC2_155 QSPLFTGTPLPESIAELTARYADTIVAVAPSGPVRLLGWSFGGSMALLIA MAV_3239|M.avium_104 RANLGLDDRTWQRLADTVDLIVDAAAVVNGVLPYQELFGPNVAGTAELIR Mb0104|M.bovis_AF2122/97 IALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGY Rv0101|M.tuberculosis_H37Rv IALTTKLKPFTYVSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGY MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QELSRRGREVTFVGMLDARTDTADPNAGFDPEAVLAGLLREMGFGVDPQA MAV_3239|M.avium_104 LALSTRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGNGY Mb0104|M.bovis_AF2122/97 GTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMV Rv0101|M.tuberculosis_H37Rv GTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMV MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RMTVADAVALVRDTDDAI-------------------------TVLDDEQ MAV_3239|M.avium_104 GNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAGQLNLPDMFTRLL Mb0104|M.bovis_AF2122/97 LSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSS Rv0101|M.tuberculosis_H37Rv LSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVAGSS MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IALVIENYVAAERLTADADYGRYDGDVFFVDATILEMDLAGVASRGWHDH MAV_3239|M.avium_104 FSVVASGVAPRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGRDA Mb0104|M.bovis_AF2122/97 LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASL Rv0101|M.tuberculosis_H37Rv LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASL MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VGGRLKVAELDCRHSELMDAEVLERLGPLIAAELRGGDVASG-------- MAV_3239|M.avium_104 GTGFATYHVMNPHDDGIGLDEYVDWLIDAGYPIERVDDFDQWLHRMETAL Mb0104|M.bovis_AF2122/97 GALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVG Rv0101|M.tuberculosis_H37Rv GALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVG MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3239|M.avium_104 HALSERQRHQSVLQLLALRNARHVPPADPARGCLGPTERFRAAVQEAKIG Mb0104|M.bovis_AF2122/97 SDKDNPDIPHVSAPTIINYVTNLQLLGLL Rv0101|M.tuberculosis_H37Rv SDKDNPDIPHVSAPTIINYVTNLQLLGLL MMAR_0256|M.marinum_M ----------------------------- MUL_4858|M.ulcerans_Agy99 ----------------------------- MLBr_01996|M.leprae_Br4923 ----------------------------- MAB_0663|M.abscessus_ATCC_1997 ----------------------------- TH_3141|M.thermoresistible__bu ----------------------------- Mvan_3845|M.vanbaalenii_PYR-1 ----------------------------- Mflv_2696|M.gilvum_PYR-GCK ----------------------------- MSMEG_0019|M.smegmatis_MC2_155 ----------------------------- MAV_3239|M.avium_104 ADNDIPHITAPVIVKYVTDLQLLGLL---