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MAVVDDLAPGMDSSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAIL DLYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVV QYGYAGAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELD EVTNGLHPGQMVIVAARPGVGKSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSDMR SGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIVVDYLQLMTSGKKYESR QVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGE LMRSGERPMVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFEGWTPLAQLKVGD RIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDEANLAAVTVSAAHSDRAAIRDDYL AARVPSLRPARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVRWD PTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHGAKDQVRFLRHVGVHGAEA VAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLSAKQMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRA IHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAFDRDDPRG GEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0058 | dnaB | - | 100% (874) | replicative DNA helicase |
| M. tuberculosis H37Rv | Rv2737c | recA | 3e-19 | 25.33% (450) | DNA recombination protein RecA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0059 | dnaB | 0.0 | 99.89% (874) | replicative DNA helicase |
| M. gilvum PYR-GCK | Mflv_0878 | - | 1e-108 | 80.58% (242) | DnaB domain-containing protein |
| M. leprae Br4923 | MLBr_02680 | dnaB | 1e-118 | 90.38% (239) | replicative DNA helicase |
| M. abscessus ATCC 19977 | MAB_4895c | - | 0.0 | 86.53% (401) | replicative DNA helicase |
| M. marinum M | MMAR_0076 | dnaB | 0.0 | 93.05% (403) | replicative DNA helicase DnaB |
| M. avium 104 | MAV_0079 | - | 1e-119 | 91.18% (238) | replicative DNA helicase |
| M. smegmatis MC2 155 | MSMEG_6892 | - | 0.0 | 68.79% (676) | replicative DNA helicase |
| M. thermoresistible (build 8) | TH_1409 | dnaB | 1e-121 | 60.45% (359) | PROBABLE REPLICATIVE DNA HELICASE DNAB |
| M. ulcerans Agy99 | MUL_0075 | dnaB | 0.0 | 92.56% (403) | replicative DNA helicase DnaB |
| M. vanbaalenii PYR-1 | Mvan_6030 | - | 1e-107 | 84.38% (224) | DnaB domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0058|M.tuberculosis_H37Rv MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI
Mb0059|M.bovis_AF2122/97 MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI
Mflv_0878|M.gilvum_PYR-GCK MAVVDDRGR-SGDRSDLEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV
Mvan_6030|M.vanbaalenii_PYR-1 ----------------MEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV
MAV_0079|M.avium_104 MAVVDDLTS-GMD----SSSPSEDFGRQPPQDLAAEQAVLGGMLLSKDAI
MMAR_0076|M.marinum_M MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV
MLBr_02680|M.leprae_Br4923 MAVVDDLAH-SGMD---AVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAI
MUL_0075|M.ulcerans_Agy99 MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV
MAB_4895c|M.abscessus_ATCC_199 MAIVDDLGQ-SGP----AAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDAI
MSMEG_6892|M.smegmatis_MC2_155 ---MDDLGHPDGPADIDGPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDAI
TH_1409|M.thermoresistible__bu ------VRR--------QPVRYAGTDEWNLQALSTAARRFGVTAVRDDHA
. .. * :: :* : .*
Rv0058|M.tuberculosis_H37Rv ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
Mb0059|M.bovis_AF2122/97 ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
Mflv_0878|M.gilvum_PYR-GCK ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR
Mvan_6030|M.vanbaalenii_PYR-1 ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR
MAV_0079|M.avium_104 ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRNLLR
MMAR_0076|M.marinum_M ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR
MLBr_02680|M.leprae_Br4923 ADVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
MUL_0075|M.ulcerans_Agy99 ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR
MAB_4895c|M.abscessus_ATCC_199 ADVLEKLRPHDFYRPNHQSVYEAILDLYGRGEPADAVTVAAELDRRGQLR
MSMEG_6892|M.smegmatis_MC2_155 ADVLERLRPGDFYRPAHQSVYDAILDLYGRGEPADAVTVAAELDRRGLLR
TH_1409|M.thermoresistible__bu AARVTTLRLPAPYRLTHG----------------TRDPIAAWLDRLGLFG
* : ** *: : .:** *** . :
Rv0058|M.tuberculosis_H37Rv RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA
Mb0059|M.bovis_AF2122/97 RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA
Mflv_0878|M.gilvum_PYR-GCK RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA
Mvan_6030|M.vanbaalenii_PYR-1 RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA
MAV_0079|M.avium_104 RIGGAPYLHTLISTVPTAANAGYYATIVAEKALLRRLVEAGTRVVQYGYA
MMAR_0076|M.marinum_M RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA
MLBr_02680|M.leprae_Br4923 RIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA
MUL_0075|M.ulcerans_Agy99 RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA
MAB_4895c|M.abscessus_ATCC_199 RVGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA
MSMEG_6892|M.smegmatis_MC2_155 RIGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRVVQYGYA
TH_1409|M.thermoresistible__bu KSGHEKFVPAEVFRLPNDQIA----------LFLRHLWATDGSVRWDGRA
: * :: : : :*. * :**:* :. * * *
Rv0058|M.tuberculosis_H37Rv GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS
Mb0059|M.bovis_AF2122/97 GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS
Mflv_0878|M.gilvum_PYR-GCK GADGADVNEIVDRAQAEIYDVTERKSSEDYVILEEILQPAMDEIDAIASQ
Mvan_6030|M.vanbaalenii_PYR-1 GADGADVNEIVDRAQAEIYDVTERKSSEDFVILEEILQPAMDEIDAIASE
MAV_0079|M.avium_104 GAEGADVAEVVDRAQAEIYEVAERRTTEDFVPLEDLLQPTMDEIDAIASN
MMAR_0076|M.marinum_M GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN
MLBr_02680|M.leprae_Br4923 GAEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIASN
MUL_0075|M.ulcerans_Agy99 GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN
MAB_4895c|M.abscessus_ATCC_199 GAEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIASA
MSMEG_6892|M.smegmatis_MC2_155 GADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQ
TH_1409|M.thermoresistible__bu GQG------------RIYYASTSRRVVDDVMLLLLRLG--------IAAR
* * :. : :: : * * **:
Rv0058|M.tuberculosis_H37Rv GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG--------------
Mb0059|M.bovis_AF2122/97 GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG--------------
Mflv_0878|M.gilvum_PYR-GCK GGISKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG
Mvan_6030|M.vanbaalenii_PYR-1 GGVSKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG
MAV_0079|M.avium_104 GGVARGVPTGFTELDEVTNGLHAGQMIIVAARPGVGKALALDTPLPTPTG
MMAR_0076|M.marinum_M GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG--------------
MLBr_02680|M.leprae_Br4923 GGISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPTG
MUL_0075|M.ulcerans_Agy99 GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG--------------
MAB_4895c|M.abscessus_ATCC_199 GGISKGVPTGFTDLDEITNGLHPGQMIIVAARPGVG--------------
MSMEG_6892|M.smegmatis_MC2_155 GGIARGVPTGFTELDEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPSG
TH_1409|M.thermoresistible__bu --IKRVTKARFRDS---------WHLVIHGAENQLR--------------
: : . : * : :::: .*. :
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK WTTMAEVKVGDFLIGADGKPTRVVAATNVMVDRPCFEVEFSDGTVLVADA
Mvan_6030|M.vanbaalenii_PYR-1 WTTMADVAVGDLLIGADGKPTRVVAATEVMVGRPCYEVEFSDGTVIVADA
MAV_0079|M.avium_104 WTTMGDVAVGDELLGDDGRPTRVVAATDVMLGRPCYEVEFSDGTVIVADA
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 WTAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVADA
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 WTTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRPCYVVEFSDGTAIVADA
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK EHQWLTETRASRKSAQAAAVGYNRTKNQRTFAAVRTTREIAETLRCPTVD
Mvan_6030|M.vanbaalenii_PYR-1 EHQWLTETRASRKSAQAAAVGYNRYKNQRTFAAVRTTREIGETLRCPTAD
MAV_0079|M.avium_104 AHQWLTETRVSRKSAQAAAVGYNRYKNQRTFAAVRTTAEIAETLRCPAQD
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 QHQWPTSYG-----------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 QHQWPTEHG-----------------------------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK RRLNHSIVNTAPIQGVEKDLLVPPYTLGAWLGDGTSAAAQITTADPEVLM
Mvan_6030|M.vanbaalenii_PYR-1 RRLNHSVVNAAPIEAPVADLLLPPYTLGAWLGDGTSRAAQITTADPEILM
MAV_0079|M.avium_104 RRLNHSVVNARALELPDREFLVPPYTLGAWLGDGTSAAAQITAADPEIIM
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 --------------------------------------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK RIEGEGLVTVPSKSAKMRYQILLPEAEPTGVRSCAVCGQDFVPQTSQVRT
Mvan_6030|M.vanbaalenii_PYR-1 RIEAEGLVTVPLPGARMRYGLQLPTEAPAGTRECVVCGASFTPSTSQVRT
MAV_0079|M.avium_104 RIEAE---------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 --------------------------------------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK CGRSCGGRVRFLTDPVPAPTCATCGGPSCGLRMCKSCRGAFGSVQARLRT
Mvan_6030|M.vanbaalenii_PYR-1 CGRSCGGRARFVSEPVAAPTCSHCGGPSCGLRLCQSCRNAVGTVQGRLRT
MAV_0079|M.avium_104 -----------------------------------DSGAGVGTLQARLRT
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 --------------------------------------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK IGVLGAKHIPIDYLRASEEQRRALLAGLLDTDGTVPNGGSVQYTGTNARL
Mvan_6030|M.vanbaalenii_PYR-1 IGVLGNKHIPTEYLRASEAQRRALLAGLLDTDGTVTNGGAVQFSVTSRRL
MAV_0079|M.avium_104 IGVLGNKHIPTEYLRGSEAQRRALLAGLLDTDGTVTVGGAVQFSVTNQRL
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 --------------------------------------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK IGDVAELVVSLGYRCQIAKKAVNGRSADSSVAYTINFSTDDVVFGLHRKA
Mvan_6030|M.vanbaalenii_PYR-1 AADVAELVVSLGYRCQVATKAVKGRTEASSTAYILNFSTTDSVFGLHRKD
MAV_0079|M.avium_104 ARDVNELIVSLGYRCQTSTKRVQGRSETSSIAYTLTFSTADKVFALERKA
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 ------IRTSAQLRCGLDIIAAAGSTP-----------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 ----VRITANLRAGMHTVVSASGGRGG-----------------------
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv --------------------------------------------------
Mb0059|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0878|M.gilvum_PYR-GCK VLHKERRRSASTVRSGSRFITDVRPVPSVPVRCVEVDNDDHLYLAGRSMI
Mvan_6030|M.vanbaalenii_PYR-1 LSHKERR-SKSSVRSNTRFIVDVREIETVPVRCVEVDNDDHMYLASRSMI
MAV_0079|M.avium_104 IAHKERRAVTGTSRGGSRFIVDVRPIEPVAVRCVEVDNDSHMYLASRAMV
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --RHAGRLTTAAFMAPVLCIDSVRRVRSVPVRCVEVDNAAHLYLAGRGMV
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 ----------TALLAPAVQITAVRRRPSVPVRCVEVDNPEHLYLAGPGMV
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
Mb0059|M.bovis_AF2122/97 ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
Mflv_0878|M.gilvum_PYR-GCK PTHNSTLGLDFMRSCSIKHQLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD
Mvan_6030|M.vanbaalenii_PYR-1 PTHNSTLGLDFMRSCSIKHHLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD
MAV_0079|M.avium_104 PTHNSTLGLDFLRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
MMAR_0076|M.marinum_M ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD
MLBr_02680|M.leprae_Br4923 PTHNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKLAD
MUL_0075|M.ulcerans_Agy99 ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD
MAB_4895c|M.abscessus_ATCC_199 ---KSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKLGD
MSMEG_6892|M.smegmatis_MC2_155 PTHNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLGD
TH_1409|M.thermoresistible__bu ----------FLRHVGVKG-LEDVAAQTVITKLERVVRNPDVDT------
*:* .:: : .: . ::* * *:* ..::
Rv0058|M.tuberculosis_H37Rv MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA
Mb0059|M.bovis_AF2122/97 MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA
Mflv_0878|M.gilvum_PYR-GCK MRSGRMNDDDWTKLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA
Mvan_6030|M.vanbaalenii_PYR-1 MRSGRMNDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA
MAV_0079|M.avium_104 MRSGRMSDEDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA
MMAR_0076|M.marinum_M MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA
MLBr_02680|M.leprae_Br4923 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKT
MUL_0075|M.ulcerans_Agy99 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTTMEIRAKARRLRQKA
MAB_4895c|M.abscessus_ATCC_199 MRSGRMSDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLNQKA
MSMEG_6892|M.smegmatis_MC2_155 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKS
TH_1409|M.thermoresistible__bu -----VPTNVWTRVRQALADK-----RIIHREIAAAMGTQFSGSALWKRA
: : **:: : ::: * . : * : .. * :::
Rv0058|M.tuberculosis_H37Rv NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL
Mb0059|M.bovis_AF2122/97 NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL
Mflv_0878|M.gilvum_PYR-GCK DLRLIVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL
Mvan_6030|M.vanbaalenii_PYR-1 DLRLVVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL
MAV_0079|M.avium_104 DLRLVVVDYLQLMSSGKKVESRQLEVSEFSRQLKLLAKELEVPVVAISQL
MMAR_0076|M.marinum_M NLKLVVVDYLQLMTSGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL
MLBr_02680|M.leprae_Br4923 NLKLVVVDYLQLMTSGKRFESRQVEVSEFSRHLKLLAKELELPVVAISQL
MUL_0075|M.ulcerans_Agy99 NLKLVVVDYLQLMISGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL
MAB_4895c|M.abscessus_ATCC_199 GLKLVVVDYLQLMTSGKKHESRQQEVSEFSRNLKLLAKELEVPVIAISQL
MSMEG_6892|M.smegmatis_MC2_155 DLRLIVVDYMQLMTSGKKYESRQQEVSDFSRSLKLMAKELDVPVVAISQL
TH_1409|M.thermoresistible__bu PSRDRLHRIAALLEDRERHDTATDDVHWDT----------LVEITSIGEH
: : *: . :: :: :* : : : ::.:
Rv0058|M.tuberculosis_H37Rv NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP
Mb0059|M.bovis_AF2122/97 NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP
Mflv_0878|M.gilvum_PYR-GCK NRGPEQRTDKKPMLSDLRESG-----------------------------
Mvan_6030|M.vanbaalenii_PYR-1 NRGPEQRTDKKPMLSDLRESG-----------------------------
MAV_0079|M.avium_104 NRGPEQRTDKKPMLSDLRESG-----------------------------
MMAR_0076|M.marinum_M NRGPEQRTDKKPMLSDLRESG-----------------------------
MLBr_02680|M.leprae_Br4923 NRSPEQRTDKKPMLSDLRESG-----------------------------
MUL_0075|M.ulcerans_Agy99 NRGPEQRTDKKPMLSDLRESG-----------------------------
MAB_4895c|M.abscessus_ATCC_199 NRGPEQRTDKRPQVSDLRESG-----------------------------
MSMEG_6892|M.smegmatis_MC2_155 NRGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFGELMATGERP
TH_1409|M.thermoresistible__bu DVYDATVPGTHNFVANAVSLHN----------------------------
: ...: ::: .
Rv0058|M.tuberculosis_H37Rv MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE
Mb0059|M.bovis_AF2122/97 MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 LVWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEATANHPFLTLD
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ
Mb0059|M.bovis_AF2122/97 GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 GWVPLGELKPGDRLATPRLVPEPVNTQRMHDSEVVMLAHMIGDGSCVKRQ
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv PIRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPSL-RPARQRLPRG
Mb0059|M.bovis_AF2122/97 PIRYEPVDEANLAAVTVSAAHSDGAAIRDDYLAARVPSL-RPARQRLPRG
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 PIRYASIDEGNLLAVETAAEHFGVTPIRDEYAAAQVTTLRLPAPYRLTRG
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV
Mb0059|M.bovis_AF2122/97 RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 KRNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLRHLWATDGSV
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR
Mb0059|M.bovis_AF2122/97 RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 RWDAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAKKAGYRDCWH
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW
Mb0059|M.bovis_AF2122/97 LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 VLIYGRENQKRFVAHVGVHGARGAAARDLLAELESVTQDTNLDTVPKEVW
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR
Mb0059|M.bovis_AF2122/97 AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR
Mflv_0878|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_0079|M.avium_104 --------------------------------------------------
MMAR_0076|M.marinum_M --------------------------------------------------
MLBr_02680|M.leprae_Br4923 --------------------------------------------------
MUL_0075|M.ulcerans_Agy99 --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155 SQVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLHRAASLLEDA
TH_1409|M.thermoresistible__bu --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ
Mb0059|M.bovis_AF2122/97 AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ
Mflv_0878|M.gilvum_PYR-GCK ----------------------------------------------SIEQ
Mvan_6030|M.vanbaalenii_PYR-1 ----------------------------------------------SIEQ
MAV_0079|M.avium_104 ----------------------------------------------SLEQ
MMAR_0076|M.marinum_M ----------------------------------------------SLEQ
MLBr_02680|M.leprae_Br4923 ----------------------------------------------SLEQ
MUL_0075|M.ulcerans_Agy99 ----------------------------------------------SLEQ
MAB_4895c|M.abscessus_ATCC_199 ----------------------------------------------SLEQ
MSMEG_6892|M.smegmatis_MC2_155 ALHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQGISAHNSLEQ
TH_1409|M.thermoresistible__bu ----------------------------------------------SLEQ
*:**
Rv0058|M.tuberculosis_H37Rv DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
Mb0059|M.bovis_AF2122/97 DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
Mflv_0878|M.gilvum_PYR-GCK DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTVTVAHQLHLSRF
Mvan_6030|M.vanbaalenii_PYR-1 DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTITVAHQLHLSRF
MAV_0079|M.avium_104 DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MMAR_0076|M.marinum_M DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MLBr_02680|M.leprae_Br4923 DADVVILLHRPDAFDRDDPRGGEADLILAKHRNGPTKTVTVAHQLHLSRF
MUL_0075|M.ulcerans_Agy99 DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MAB_4895c|M.abscessus_ATCC_199 DADMVILLHRPDAFERDDPRGGEADLILGKHRNGPTATITVAHQLHLSRF
MSMEG_6892|M.smegmatis_MC2_155 DADMVMLLHRPDAFDRDDPRGGEADIILGKHRNGPTANITVAHQLHFSRF
TH_1409|M.thermoresistible__bu DADMVILLHRPDAFDRDDPRGGEADLILGKHRNGPTKTITVAHQLHLSRF
***:*:**:*****: *********:*:.*** *** .:*******:***
Rv0058|M.tuberculosis_H37Rv ANMAR
Mb0059|M.bovis_AF2122/97 ANMAR
Mflv_0878|M.gilvum_PYR-GCK SNMAK
Mvan_6030|M.vanbaalenii_PYR-1 SNMAK
MAV_0079|M.avium_104 ANMAR
MMAR_0076|M.marinum_M ANMAR
MLBr_02680|M.leprae_Br4923 TNMAR
MUL_0075|M.ulcerans_Agy99 ANMAR
MAB_4895c|M.abscessus_ATCC_199 TNMAR
MSMEG_6892|M.smegmatis_MC2_155 TNMAR
TH_1409|M.thermoresistible__bu ANMAK
:***: