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AIVDDLGQSGPAAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDAIADVLEKLRPHDFYRPNHQSVYEAILD LYGRGEPADAVTVAAELDRRGQLRRVGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQ YGYAGAEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIASAGGISKGVPTGFTDLDE ITNGLHPGQMIIVAARPGVGKSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKLGDMRS GRMSDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLNQKAGLKLVVVDYLQLMTSGKKHESRQ QEVSEFSRNLKLLAKELEVPVIAISQLNRGPEQRTDKRPQVSDLRESGSLEQDADMVILLHRPDAFERDD PRGGEADLILGKHRNGPTATITVAHQLHLSRFTNMAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4895c | - | - | 100% (458) | replicative DNA helicase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0059 | dnaB | 0.0 | 86.53% (401) | replicative DNA helicase |
M. gilvum PYR-GCK | Mflv_0878 | - | 1e-112 | 88.05% (226) | DnaB domain-containing protein |
M. tuberculosis H37Rv | Rv0058 | dnaB | 0.0 | 86.53% (401) | replicative DNA helicase |
M. leprae Br4923 | MLBr_02680 | dnaB | 1e-114 | 85.36% (239) | replicative DNA helicase |
M. marinum M | MMAR_0076 | dnaB | 0.0 | 89.13% (460) | replicative DNA helicase DnaB |
M. avium 104 | MAV_0079 | - | 1e-111 | 89.38% (226) | replicative DNA helicase |
M. smegmatis MC2 155 | MSMEG_6892 | - | 1e-112 | 84.17% (240) | replicative DNA helicase |
M. thermoresistible (build 8) | TH_2096 | dnaB | 5e-98 | 87.06% (201) | PROBABLE REPLICATIVE DNA HELICASE DNAB |
M. ulcerans Agy99 | MUL_0075 | dnaB | 0.0 | 88.70% (460) | replicative DNA helicase DnaB |
M. vanbaalenii PYR-1 | Mvan_6030 | - | 1e-112 | 88.94% (226) | DnaB domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6892|M.smegmatis_MC2_155 MDDLGHPDGPADID----GPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDA TH_2096|M.thermoresistible__bu -------------------------------------------MLLSKDA MLBr_02680|M.leprae_Br4923 -MAVVDDLAHSGMD----AVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDA Mflv_0878|M.gilvum_PYR-GCK MAVVDDRGR--SGDRSDLEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDA Mvan_6030|M.vanbaalenii_PYR-1 -----------------MEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDA MAV_0079|M.avium_104 MAVVDDLTS--GMD----SSSPSEDFGRQPPQDLAAEQAVLGGMLLSKDA MAB_4895c|M.abscessus_ATCC_199 MAIVDDLGQ--SGP----AAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDA Mb0059|M.bovis_AF2122/97 MAVVDDLAP--GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDA Rv0058|M.tuberculosis_H37Rv MAVVDDLAP--GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDA MMAR_0076|M.marinum_M MAVVDDLAHSDNMD----APPPSEDFGRQPPQDLAAEQSVLGGMLLSKDA MUL_0075|M.ulcerans_Agy99 MAVVDDLAHSDNMD----APPPSEDFGRQPPQDLAAEQSVLGGMLLSKDA *:***** MSMEG_6892|M.smegmatis_MC2_155 IADVLERLRPGDFYRPAHQSVYDAILDLYGRGEPADAVTVAAELDRRGLL TH_2096|M.thermoresistible__bu IADVLEKLRPGDFYKPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLL MLBr_02680|M.leprae_Br4923 IADVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLL Mflv_0878|M.gilvum_PYR-GCK VADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLL Mvan_6030|M.vanbaalenii_PYR-1 VADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLL MAV_0079|M.avium_104 IADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRNLL MAB_4895c|M.abscessus_ATCC_199 IADVLEKLRPHDFYRPNHQSVYEAILDLYGRGEPADAVTVAAELDRRGQL Mb0059|M.bovis_AF2122/97 IADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLL Rv0058|M.tuberculosis_H37Rv IADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLL MMAR_0076|M.marinum_M VADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLL MUL_0075|M.ulcerans_Agy99 VADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLL :*****:**. ***:* :* :*:************************. * MSMEG_6892|M.smegmatis_MC2_155 RRIGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRVVQYGY TH_2096|M.thermoresistible__bu RRIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGY MLBr_02680|M.leprae_Br4923 RRIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGY Mflv_0878|M.gilvum_PYR-GCK RRVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGY Mvan_6030|M.vanbaalenii_PYR-1 RRVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGY MAV_0079|M.avium_104 RRIGGAPYLHTLISTVPTAANAGYYATIVAEKALLRRLVEAGTRVVQYGY MAB_4895c|M.abscessus_ATCC_199 RRVGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGY Mb0059|M.bovis_AF2122/97 RRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGY Rv0058|M.tuberculosis_H37Rv RRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGY MMAR_0076|M.marinum_M RRIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGY MUL_0075|M.ulcerans_Agy99 RRIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGY **:********************:** **.**:***************** MSMEG_6892|M.smegmatis_MC2_155 AGADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIAS TH_2096|M.thermoresistible__bu AGADGADVNEVVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIAS MLBr_02680|M.leprae_Br4923 AGAEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIAS Mflv_0878|M.gilvum_PYR-GCK AGADGADVNEIVDRAQAEIYDVTERKSSEDYVILEEILQPAMDEIDAIAS Mvan_6030|M.vanbaalenii_PYR-1 AGADGADVNEIVDRAQAEIYDVTERKSSEDFVILEEILQPAMDEIDAIAS MAV_0079|M.avium_104 AGAEGADVAEVVDRAQAEIYEVAERRTTEDFVPLEDLLQPTMDEIDAIAS MAB_4895c|M.abscessus_ATCC_199 AGAEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIAS Mb0059|M.bovis_AF2122/97 AGAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIAS Rv0058|M.tuberculosis_H37Rv AGAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIAS MMAR_0076|M.marinum_M AGAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIAS MUL_0075|M.ulcerans_Agy99 AGAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIAS ***:**** ::*******:*:*:: : :*::* **::***:**::***** MSMEG_6892|M.smegmatis_MC2_155 QGGIARGVPTGFTELDEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPS TH_2096|M.thermoresistible__bu QGGLARGVPTGFIELDEVTNGLHPGQMIIIAARPGVGKALALDTPLPTPH MLBr_02680|M.leprae_Br4923 NGGISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPT Mflv_0878|M.gilvum_PYR-GCK QGGISKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPT Mvan_6030|M.vanbaalenii_PYR-1 EGGVSKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPT MAV_0079|M.avium_104 NGGVARGVPTGFTELDEVTNGLHAGQMIIVAARPGVGKALALDTPLPTPT MAB_4895c|M.abscessus_ATCC_199 AGGISKGVPTGFTDLDEITNGLHPGQMIIVAARPGVG------------- Mb0059|M.bovis_AF2122/97 SGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVGKSTLGLDFMRSCS Rv0058|M.tuberculosis_H37Rv SGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVGKSTLGLDFMRSCS MMAR_0076|M.marinum_M NGGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVGKSTLGLDFMRSCS MUL_0075|M.ulcerans_Agy99 NGGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVGKSTLGLDFMRSCS **:::*..*** :***:*****.***:::*****:* MSMEG_6892|M.smegmatis_MC2_155 GWTTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRPCYVVEFSDGTAIVAD TH_2096|M.thermoresistible__bu GWTTMGDVAVGDELLGADGRPTRVVAATEVMLGRPCYEVEFSDGTVIVAD MLBr_02680|M.leprae_Br4923 GWTAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVAD Mflv_0878|M.gilvum_PYR-GCK GWTTMAEVKVGDFLIGADGKPTRVVAATNVMVDRPCFEVEFSDGTVLVAD Mvan_6030|M.vanbaalenii_PYR-1 GWTTMADVAVGDLLIGADGKPTRVVAATEVMVGRPCYEVEFSDGTVIVAD MAV_0079|M.avium_104 GWTTMGDVAVGDELLGDDGRPTRVVAATDVMLGRPCYEVEFSDGTVIVAD MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 IRHRMASVIFS-LEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLA Rv0058|M.tuberculosis_H37Rv IRHRMASVIFS-LEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLA MMAR_0076|M.marinum_M IKHQMASVIFS-LEMSKTEIVMRLLSAEAKIKLADMRSGRMTDDDWTRLA MUL_0075|M.ulcerans_Agy99 IKHQMASVIFS-LEMSKTEIVMRLLSAEAKIKLADMRSGRMTDDDWTRLA MSMEG_6892|M.smegmatis_MC2_155 AQHQWPTEHGVRITANLRAG---------------------MHTVVSASG TH_2096|M.thermoresistible__bu ADHQWPTGYGVRTTARLRAG---------------------LDTIAAAGS MLBr_02680|M.leprae_Br4923 AQHQWPTSYGIRTSAQLRCG---------------------LDIIAAAGS Mflv_0878|M.gilvum_PYR-GCK AEHQWLTETRASRKSAQAAAVGYNRTKNQRTFAAVRTTREIAETLRCPTV Mvan_6030|M.vanbaalenii_PYR-1 AEHQWLTETRASRKSAQAAAVGYNRYKNQRTFAAVRTTREIGETLRCPTA MAV_0079|M.avium_104 AAHQWLTETRVSRKSAQAAAVGYNRYKNQRTFAAVRTTAEIAETLRCPAQ MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 RRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIVVDYLQLMTS Rv0058|M.tuberculosis_H37Rv RRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIVVDYLQLMTS MMAR_0076|M.marinum_M RRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKANLKLVVVDYLQLMTS MUL_0075|M.ulcerans_Agy99 RRMSEISEAPLYIDDSPNLTTMEIRAKARRLRQKANLKLVVVDYLQLMIS MSMEG_6892|M.smegmatis_MC2_155 GR------GGTALLAPAVQITAVRRRPS---------------------- TH_2096|M.thermoresistible__bu MARYGEQPGGAALLAPVLQIDAVRRINS---------------------- MLBr_02680|M.leprae_Br4923 TPRHAGRLTTAAFMAPVLCIDSVRRVRS---------------------- Mflv_0878|M.gilvum_PYR-GCK DRRLNHSIVNTAPIQGVEKDLLVPPYTLGAWLGDGTSAAAQITTADPEVL Mvan_6030|M.vanbaalenii_PYR-1 DRRLNHSVVNAAPIEAPVADLLLPPYTLGAWLGDGTSRAAQITTADPEIL MAV_0079|M.avium_104 DRRLNHSVVNARALELPDREFLVPPYTLGAWLGDGTSAAAQITAADPEII MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 GKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPMLA Rv0058|M.tuberculosis_H37Rv GKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPMLA MMAR_0076|M.marinum_M GKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQLNRGPEQRTDKKPMLS MUL_0075|M.ulcerans_Agy99 GKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQLNRGPEQRTDKKPMLS MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK MRIEGEGL-VTVPSKSAKMRYQILLPEAEPTGVRSCAVCGQDFVPQTSQV Mvan_6030|M.vanbaalenii_PYR-1 MRIEAEGL-VTVPLPGARMRYGLQLPTEAPAGTRECVVCGASFTPSTSQV MAV_0079|M.avium_104 MRIEAE-------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 DLRESGCLTASTRILRADTGAEVAFGELMRSGERPMVWSLDERLRMVARP Rv0058|M.tuberculosis_H37Rv DLRESGCLTASTRILRADTGAEVAFGELMRSGERPMVWSLDERLRMVARP MMAR_0076|M.marinum_M DLRESG-------------------------------------------- MUL_0075|M.ulcerans_Agy99 DLRESG-------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RTCGRSCGGRVRFLTDPVPAPTCATCGGPSCGLRMCKSCRGAFGSVQARL Mvan_6030|M.vanbaalenii_PYR-1 RTCGRSCGGRARFVSEPVAAPTCSHCGGPSCGLRLCQSCRNAVGTVQGRL MAV_0079|M.avium_104 -------------------------------------DSGAGVGTLQARL MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 MINVFPSGRKEVFRLRLASGREVEATGSHPF------MKFEGWTPLAQLK Rv0058|M.tuberculosis_H37Rv MINVFPSGRKEVFRLRLASGREVEATGSHPF------MKFEGWTPLAQLK MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RTIGVLGAKHIPIDYLRASEEQRRALLAGLLDTDGTVPNGGSVQYTGTNA Mvan_6030|M.vanbaalenii_PYR-1 RTIGVLGNKHIPTEYLRASEAQRRALLAGLLDTDGTVTNGGAVQFSVTSR MAV_0079|M.avium_104 RTIGVLGNKHIPTEYLRGSEAQRRALLAGLLDTDGTVTVGGAVQFSVTNQ MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 VGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDE Rv0058|M.tuberculosis_H37Rv VGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDE MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RLIGDVAELVVSLGYRCQIAKKAVNGRSADSSVAYTINFSTDDVVFGLHR Mvan_6030|M.vanbaalenii_PYR-1 RLAADVAELVVSLGYRCQVATKAVKGRTEASSTAYILNFSTTDSVFGLHR MAV_0079|M.avium_104 RLARDVNELIVSLGYRCQTSTKRVQGRSETSSIAYTLTFSTADKVFALER MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 ANLAAVTVSAAHSDGAAIRDDYLAARVPSLRPARQRLPRGRCTPIAAWLA Rv0058|M.tuberculosis_H37Rv ANLAAVTVSAAHSDRAAIRDDYLAARVPSLRPARQRLPRGRCTPIAAWLA MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 ------------------------------VPVRCVEVDNPEHLYLAGPG TH_2096|M.thermoresistible__bu ------------------------------VPVRCVEVDNPAHLYLAGQG MLBr_02680|M.leprae_Br4923 ------------------------------VPVRCVEVDNAAHLYLAGRG Mflv_0878|M.gilvum_PYR-GCK KAVLHKERRRSASTVRSGSRFITDVRPVPSVPVRCVEVDNDDHLYLAGRS Mvan_6030|M.vanbaalenii_PYR-1 KDLSHKERR-SKSSVRSNTRFIVDVREIETVPVRCVEVDNDDHMYLASRS MAV_0079|M.avium_104 KAIAHKERRAVTGTSRGGSRFIVDVRPIEPVAVRCVEVDNDSHMYLASRA MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 GLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVRWDPTNGQGR Rv0058|M.tuberculosis_H37Rv GLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVRWDPTNGQGR MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 MVPTHNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKL TH_2096|M.thermoresistible__bu MVPTHNSTLGLDFMRSCSIKHRMASIIFSLEMSKSEIVMRLLSAEAKIKL MLBr_02680|M.leprae_Br4923 MVPTHNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKL Mflv_0878|M.gilvum_PYR-GCK MIPTHNSTLGLDFMRSCSIKHQLPSIVFSLEMSKTEIVMRLLSAEAKIKL Mvan_6030|M.vanbaalenii_PYR-1 MIPTHNSTLGLDFMRSCSIKHHLPSIVFSLEMSKTEIVMRLLSAEAKIKL MAV_0079|M.avium_104 MVPTHNSTLGLDFLRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKL MAB_4895c|M.abscessus_ATCC_199 -----KSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKL Mb0059|M.bovis_AF2122/97 VYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHGAKDQV Rv0058|M.tuberculosis_H37Rv VYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHGAKDQV MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 GDMRSGRMTDDDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL TH_2096|M.thermoresistible__bu SDMRSGRMTDDDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL MLBr_02680|M.leprae_Br4923 ADMRSGRMTDDDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL Mflv_0878|M.gilvum_PYR-GCK ADMRSGRMNDDDWTKLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL Mvan_6030|M.vanbaalenii_PYR-1 ADMRSGRMNDDDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL MAV_0079|M.avium_104 SDMRSGRMSDEDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL MAB_4895c|M.abscessus_ATCC_199 GDMRSGRMSDDDWTRLARRMSEISEAP--LYIDDSPNLTMMEIRAKARRL Mb0059|M.bovis_AF2122/97 RFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLS-A Rv0058|M.tuberculosis_H37Rv RFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLS-A MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 AQKSDLRLIVVDYMQLMTSG---KKYESRQQE--VSDFSRSLKLMAKELD TH_2096|M.thermoresistible__bu AQKADLRLVVVDYMQLMTSG---KKYESRQQE--VSDFSRSLKLMAKELD MLBr_02680|M.leprae_Br4923 RQKTNLKLVVVDYLQLMTSG---KRFESRQVE--VSEFSRHLKLLAKELE Mflv_0878|M.gilvum_PYR-GCK KQKADLRLIVIDYLQLMTSG---KKVESRQQE--VSEFSRQIKLLAKELE Mvan_6030|M.vanbaalenii_PYR-1 KQKADLRLVVIDYLQLMTSG---KKVESRQQE--VSEFSRQIKLLAKELE MAV_0079|M.avium_104 RQKADLRLVVVDYLQLMSSG---KKVESRQLE--VSEFSRQLKLLAKELE MAB_4895c|M.abscessus_ATCC_199 NQKAGLKLVVVDYLQLMTSG---KKHESRQQE--VSEFSRNLKLLAKELE Mb0059|M.bovis_AF2122/97 KQMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRAIHELARGDAYWDTVVE Rv0058|M.tuberculosis_H37Rv KQMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRAIHELARGDAYWDTVVE MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 VPVVAISQLNRGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFG TH_2096|M.thermoresistible__bu LPVVAISQLNRGPEQRTDKKPQVSDLRESGCLTANTRLLRADTGAEVTFG MLBr_02680|M.leprae_Br4923 LPVVAISQLNRSPEQRTDKKPMLSDLRESGSLEQDADVVILLHRPDAFDR Mflv_0878|M.gilvum_PYR-GCK VPVVAMSQLNRGPEQRTDKKPMLSDLRESGSIEQDADMVILLHRPDAFES Mvan_6030|M.vanbaalenii_PYR-1 VPVVAMSQLNRGPEQRTDKKPMLSDLRESGSIEQDADMVILLHRPDAFES MAV_0079|M.avium_104 VPVVAISQLNRGPEQRTDKKPMLSDLRESGSLEQDADMVILLNRPDAFER MAB_4895c|M.abscessus_ATCC_199 VPVIAISQLNRGPEQRTDKRPQVSDLRESGSLEQDADMVILLHRPDAFER Mb0059|M.bovis_AF2122/97 ITSIGDQHVFDGTVSGTHNF-VANGISLHNSLEQDADVVILLHRPDAFDR Rv0058|M.tuberculosis_H37Rv ITSIGDQHVFDGTVSGTHNF-VANGISLHNSLEQDADVVILLHRPDAFDR MMAR_0076|M.marinum_M ------------------------------SLEQDADMVILLNRPDAFER MUL_0075|M.ulcerans_Agy99 ------------------------------SLEQDADMVILLNRPDAFER .: :: :: .:. MSMEG_6892|M.smegmatis_MC2_155 ELMATGERPLVWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEAT TH_2096|M.thermoresistible__bu ELMATGERPLVWSLDDRNRMVARPVSNVFYSGRKEVFKVRLASGRGXAVR MLBr_02680|M.leprae_Br4923 DDPRGGEADLILAKHRNGPTKTVTVAHQLHLSR---FTN-MAR------- Mflv_0878|M.gilvum_PYR-GCK DDPRGGEADLIVAKHRAGPTRTVTVAHQLHLSR----FSNMAK------- Mvan_6030|M.vanbaalenii_PYR-1 DDPRGGEADLIVAKHRAGPTRTITVAHQLHLSR----FSNMAK------- MAV_0079|M.avium_104 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSR----FANMAR------- MAB_4895c|M.abscessus_ATCC_199 DDPRGGEADLILGKHRNGPTATITVAHQLHLSR----FTNMAR------- Mb0059|M.bovis_AF2122/97 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSR----FANMAR------- Rv0058|M.tuberculosis_H37Rv DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSR----FANMAR------- MMAR_0076|M.marinum_M DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSR----FANMAR------- MUL_0075|M.ulcerans_Agy99 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSR----FANMAR------- : ** :: . . : .::: : .* :* MSMEG_6892|M.smegmatis_MC2_155 ANHPFLTLDGWVPLGELKPGDRLATPRLVPEPVNTQRMHDSEVVMLAHMI TH_2096|M.thermoresistible__bu ADA----------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 GDGSCVKRQPIRYASIDEGNLLAVETAAEHFGVTPIRDEYAAAQVTTLRL TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 PAPYRLTRGKRNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLR TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 HLWATDGSVRWDAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAK TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 KAGYRDCWHVLIYGRENQKRFVAHVGVHGARGAAARDLLAELESVTQDTN TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 LDTVPKEVWSQVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLH TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 RAASLLEDAALHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQG TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 ISAHNSLEQDADMVMLLHRPDAFDRDDPRGGEADIILGKHRNGPTANITV TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 AHQLHFSRFTNMAR TH_2096|M.thermoresistible__bu -------------- MLBr_02680|M.leprae_Br4923 -------------- Mflv_0878|M.gilvum_PYR-GCK -------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------- MAV_0079|M.avium_104 -------------- MAB_4895c|M.abscessus_ATCC_199 -------------- Mb0059|M.bovis_AF2122/97 -------------- Rv0058|M.tuberculosis_H37Rv -------------- MMAR_0076|M.marinum_M -------------- MUL_0075|M.ulcerans_Agy99 --------------