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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1409 | dnaB | - | 100% (360) | PROBABLE REPLICATIVE DNA HELICASE DNAB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0059 | dnaB | 1e-121 | 60.45% (359) | replicative DNA helicase |
M. gilvum PYR-GCK | Mflv_0878 | - | 4e-25 | 84.75% (59) | DnaB domain-containing protein |
M. tuberculosis H37Rv | Rv0058 | dnaB | 1e-121 | 60.45% (359) | replicative DNA helicase |
M. leprae Br4923 | MLBr_02680 | dnaB | 1e-27 | 91.53% (59) | replicative DNA helicase |
M. abscessus ATCC 19977 | MAB_4895c | - | 2e-27 | 93.22% (59) | replicative DNA helicase |
M. marinum M | MMAR_0076 | dnaB | 3e-26 | 89.83% (59) | replicative DNA helicase DnaB |
M. avium 104 | MAV_0079 | - | 2e-26 | 89.83% (59) | replicative DNA helicase |
M. smegmatis MC2 155 | MSMEG_6892 | - | 1e-151 | 69.64% (359) | replicative DNA helicase |
M. ulcerans Agy99 | MUL_0075 | dnaB | 2e-26 | 89.83% (59) | replicative DNA helicase DnaB |
M. vanbaalenii PYR-1 | Mvan_6030 | - | 4e-25 | 86.44% (59) | DnaB domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0878|M.gilvum_PYR-GCK MAVVDDRGR-SGDRSDLEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV Mvan_6030|M.vanbaalenii_PYR-1 ----------------MEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV MAV_0079|M.avium_104 MAVVDDLTS-GMD----SSSPSEDFGRQPPQDLAAEQAVLGGMLLSKDAI MMAR_0076|M.marinum_M MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV MLBr_02680|M.leprae_Br4923 MAVVDDLAH-SGMD---AVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAI MUL_0075|M.ulcerans_Agy99 MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV MAB_4895c|M.abscessus_ATCC_199 MAIVDDLGQ-SGP----AAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDAI Mb0059|M.bovis_AF2122/97 MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI Rv0058|M.tuberculosis_H37Rv MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI MSMEG_6892|M.smegmatis_MC2_155 ---MDDLGHPDGPADIDGPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDAI TH_1409|M.thermoresistible__bu ------VRR--------QPVRYAGTDEWNLQALSTAARRFGVTAVRDDHA . .. * :: :* : .* Mflv_0878|M.gilvum_PYR-GCK ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR Mvan_6030|M.vanbaalenii_PYR-1 ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR MAV_0079|M.avium_104 ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRNLLR MMAR_0076|M.marinum_M ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR MLBr_02680|M.leprae_Br4923 ADVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR MUL_0075|M.ulcerans_Agy99 ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR MAB_4895c|M.abscessus_ATCC_199 ADVLEKLRPHDFYRPNHQSVYEAILDLYGRGEPADAVTVAAELDRRGQLR Mb0059|M.bovis_AF2122/97 ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR Rv0058|M.tuberculosis_H37Rv ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR MSMEG_6892|M.smegmatis_MC2_155 ADVLERLRPGDFYRPAHQSVYDAILDLYGRGEPADAVTVAAELDRRGLLR TH_1409|M.thermoresistible__bu AARVTTLRLPAPYRLTHG----------------TRDPIAAWLDRLGLFG * : ** *: : .:** *** . : Mflv_0878|M.gilvum_PYR-GCK RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA Mvan_6030|M.vanbaalenii_PYR-1 RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA MAV_0079|M.avium_104 RIGGAPYLHTLISTVPTAANAGYYATIVAEKALLRRLVEAGTRVVQYGYA MMAR_0076|M.marinum_M RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA MLBr_02680|M.leprae_Br4923 RIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA MUL_0075|M.ulcerans_Agy99 RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA MAB_4895c|M.abscessus_ATCC_199 RVGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA Mb0059|M.bovis_AF2122/97 RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA Rv0058|M.tuberculosis_H37Rv RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA MSMEG_6892|M.smegmatis_MC2_155 RIGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRVVQYGYA TH_1409|M.thermoresistible__bu KSGHEKFVPAEVFRLPNDQIA----------LFLRHLWATDGSVRWDGRA : * :: : : :*. * :**:* :. * * * Mflv_0878|M.gilvum_PYR-GCK GADGADVNEIVDRAQAEIYDVTERKSSEDYVILEEILQPAMDEIDAIASQ Mvan_6030|M.vanbaalenii_PYR-1 GADGADVNEIVDRAQAEIYDVTERKSSEDFVILEEILQPAMDEIDAIASE MAV_0079|M.avium_104 GAEGADVAEVVDRAQAEIYEVAERRTTEDFVPLEDLLQPTMDEIDAIASN MMAR_0076|M.marinum_M GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN MLBr_02680|M.leprae_Br4923 GAEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIASN MUL_0075|M.ulcerans_Agy99 GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN MAB_4895c|M.abscessus_ATCC_199 GAEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIASA Mb0059|M.bovis_AF2122/97 GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS Rv0058|M.tuberculosis_H37Rv GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS MSMEG_6892|M.smegmatis_MC2_155 GADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQ TH_1409|M.thermoresistible__bu GQG------------RIYYASTSRRVVDDVMLLLLRLG--------IAAR * * :. : :: : * * **: Mflv_0878|M.gilvum_PYR-GCK GGISKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG Mvan_6030|M.vanbaalenii_PYR-1 GGVSKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG MAV_0079|M.avium_104 GGVARGVPTGFTELDEVTNGLHAGQMIIVAARPGVGKALALDTPLPTPTG MMAR_0076|M.marinum_M GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG-------------- MLBr_02680|M.leprae_Br4923 GGISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPTG MUL_0075|M.ulcerans_Agy99 GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG-------------- MAB_4895c|M.abscessus_ATCC_199 GGISKGVPTGFTDLDEITNGLHPGQMIIVAARPGVG-------------- Mb0059|M.bovis_AF2122/97 GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG-------------- Rv0058|M.tuberculosis_H37Rv GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG-------------- MSMEG_6892|M.smegmatis_MC2_155 GGIARGVPTGFTELDEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPSG TH_1409|M.thermoresistible__bu --IKRVTKARFRDS---------WHLVIHGAENQLR-------------- : : . : * : :::: .*. : Mflv_0878|M.gilvum_PYR-GCK WTTMAEVKVGDFLIGADGKPTRVVAATNVMVDRPCFEVEFSDGTVLVADA Mvan_6030|M.vanbaalenii_PYR-1 WTTMADVAVGDLLIGADGKPTRVVAATEVMVGRPCYEVEFSDGTVIVADA MAV_0079|M.avium_104 WTTMGDVAVGDELLGDDGRPTRVVAATDVMLGRPCYEVEFSDGTVIVADA MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 WTAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVADA MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 WTTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRPCYVVEFSDGTAIVADA TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK EHQWLTETRASRKSAQAAAVGYNRTKNQRTFAAVRTTREIAETLRCPTVD Mvan_6030|M.vanbaalenii_PYR-1 EHQWLTETRASRKSAQAAAVGYNRYKNQRTFAAVRTTREIGETLRCPTAD MAV_0079|M.avium_104 AHQWLTETRVSRKSAQAAAVGYNRYKNQRTFAAVRTTAEIAETLRCPAQD MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 QHQWPTSYG----------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 QHQWPTEHG----------------------------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RRLNHSIVNTAPIQGVEKDLLVPPYTLGAWLGDGTSAAAQITTADPEVLM Mvan_6030|M.vanbaalenii_PYR-1 RRLNHSVVNAAPIEAPVADLLLPPYTLGAWLGDGTSRAAQITTADPEILM MAV_0079|M.avium_104 RRLNHSVVNARALELPDREFLVPPYTLGAWLGDGTSAAAQITAADPEIIM MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RIEGEGLVTVPSKSAKMRYQILLPEAEPTGVRSCAVCGQDFVPQTSQVRT Mvan_6030|M.vanbaalenii_PYR-1 RIEAEGLVTVPLPGARMRYGLQLPTEAPAGTRECVVCGASFTPSTSQVRT MAV_0079|M.avium_104 RIEAE--------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK CGRSCGGRVRFLTDPVPAPTCATCGGPSCGLRMCKSCRGAFGSVQARLRT Mvan_6030|M.vanbaalenii_PYR-1 CGRSCGGRARFVSEPVAAPTCSHCGGPSCGLRLCQSCRNAVGTVQGRLRT MAV_0079|M.avium_104 -----------------------------------DSGAGVGTLQARLRT MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK IGVLGAKHIPIDYLRASEEQRRALLAGLLDTDGTVPNGGSVQYTGTNARL Mvan_6030|M.vanbaalenii_PYR-1 IGVLGNKHIPTEYLRASEAQRRALLAGLLDTDGTVTNGGAVQFSVTSRRL MAV_0079|M.avium_104 IGVLGNKHIPTEYLRGSEAQRRALLAGLLDTDGTVTVGGAVQFSVTNQRL MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK IGDVAELVVSLGYRCQIAKKAVNGRSADSSVAYTINFSTDDVVFGLHRKA Mvan_6030|M.vanbaalenii_PYR-1 AADVAELVVSLGYRCQVATKAVKGRTEASSTAYILNFSTTDSVFGLHRKD MAV_0079|M.avium_104 ARDVNELIVSLGYRCQTSTKRVQGRSETSSIAYTLTFSTADKVFALERKA MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 ------IRTSAQLRCGLDIIAAAGSTP----------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 ----VRITANLRAGMHTVVSASGGRGG----------------------- TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK VLHKERRRSASTVRSGSRFITDVRPVPSVPVRCVEVDNDDHLYLAGRSMI Mvan_6030|M.vanbaalenii_PYR-1 LSHKERR-SKSSVRSNTRFIVDVREIETVPVRCVEVDNDDHMYLASRSMI MAV_0079|M.avium_104 IAHKERRAVTGTSRGGSRFIVDVRPIEPVAVRCVEVDNDSHMYLASRAMV MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 --RHAGRLTTAAFMAPVLCIDSVRRVRSVPVRCVEVDNAAHLYLAGRGMV MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 ----------TALLAPAVQITAVRRRPSVPVRCVEVDNPEHLYLAGPGMV TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK PTHNSTLGLDFMRSCSIKHQLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD Mvan_6030|M.vanbaalenii_PYR-1 PTHNSTLGLDFMRSCSIKHHLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD MAV_0079|M.avium_104 PTHNSTLGLDFLRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD MMAR_0076|M.marinum_M ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD MLBr_02680|M.leprae_Br4923 PTHNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKLAD MUL_0075|M.ulcerans_Agy99 ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD MAB_4895c|M.abscessus_ATCC_199 ---KSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKLGD Mb0059|M.bovis_AF2122/97 ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD Rv0058|M.tuberculosis_H37Rv ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD MSMEG_6892|M.smegmatis_MC2_155 PTHNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLGD TH_1409|M.thermoresistible__bu ----------FLRHVGVKG-LEDVAAQTVITKLERVVRNPDVDT------ *:* .:: : .: . ::* * *:* ..:: Mflv_0878|M.gilvum_PYR-GCK MRSGRMNDDDWTKLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA Mvan_6030|M.vanbaalenii_PYR-1 MRSGRMNDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA MAV_0079|M.avium_104 MRSGRMSDEDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA MMAR_0076|M.marinum_M MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA MLBr_02680|M.leprae_Br4923 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKT MUL_0075|M.ulcerans_Agy99 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTTMEIRAKARRLRQKA MAB_4895c|M.abscessus_ATCC_199 MRSGRMSDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLNQKA Mb0059|M.bovis_AF2122/97 MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA Rv0058|M.tuberculosis_H37Rv MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA MSMEG_6892|M.smegmatis_MC2_155 MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKS TH_1409|M.thermoresistible__bu -----VPTNVWTRVRQALADK-----RIIHREIAAAMGTQFSGSALWKRA : : **:: : ::: * . : * : .. * ::: Mflv_0878|M.gilvum_PYR-GCK DLRLIVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL Mvan_6030|M.vanbaalenii_PYR-1 DLRLVVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL MAV_0079|M.avium_104 DLRLVVVDYLQLMSSGKKVESRQLEVSEFSRQLKLLAKELEVPVVAISQL MMAR_0076|M.marinum_M NLKLVVVDYLQLMTSGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL MLBr_02680|M.leprae_Br4923 NLKLVVVDYLQLMTSGKRFESRQVEVSEFSRHLKLLAKELELPVVAISQL MUL_0075|M.ulcerans_Agy99 NLKLVVVDYLQLMISGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL MAB_4895c|M.abscessus_ATCC_199 GLKLVVVDYLQLMTSGKKHESRQQEVSEFSRNLKLLAKELEVPVIAISQL Mb0059|M.bovis_AF2122/97 NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL Rv0058|M.tuberculosis_H37Rv NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL MSMEG_6892|M.smegmatis_MC2_155 DLRLIVVDYMQLMTSGKKYESRQQEVSDFSRSLKLMAKELDVPVVAISQL TH_1409|M.thermoresistible__bu PSRDRLHRIAALLEDRERHDTATDDVHWDT----------LVEITSIGEH : : *: . :: :: :* : : : ::.: Mflv_0878|M.gilvum_PYR-GCK NRGPEQRTDKKPMLSDLRESG----------------------------- Mvan_6030|M.vanbaalenii_PYR-1 NRGPEQRTDKKPMLSDLRESG----------------------------- MAV_0079|M.avium_104 NRGPEQRTDKKPMLSDLRESG----------------------------- MMAR_0076|M.marinum_M NRGPEQRTDKKPMLSDLRESG----------------------------- MLBr_02680|M.leprae_Br4923 NRSPEQRTDKKPMLSDLRESG----------------------------- MUL_0075|M.ulcerans_Agy99 NRGPEQRTDKKPMLSDLRESG----------------------------- MAB_4895c|M.abscessus_ATCC_199 NRGPEQRTDKRPQVSDLRESG----------------------------- Mb0059|M.bovis_AF2122/97 NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP Rv0058|M.tuberculosis_H37Rv NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP MSMEG_6892|M.smegmatis_MC2_155 NRGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFGELMATGERP TH_1409|M.thermoresistible__bu DVYDATVPGTHNFVANAVSLHN---------------------------- : ...: ::: . Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE Rv0058|M.tuberculosis_H37Rv MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE MSMEG_6892|M.smegmatis_MC2_155 LVWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEATANHPFLTLD TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ Rv0058|M.tuberculosis_H37Rv GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ MSMEG_6892|M.smegmatis_MC2_155 GWVPLGELKPGDRLATPRLVPEPVNTQRMHDSEVVMLAHMIGDGSCVKRQ TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 PIRYEPVDEANLAAVTVSAAHSDGAAIRDDYLAARVPSL-RPARQRLPRG Rv0058|M.tuberculosis_H37Rv PIRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPSL-RPARQRLPRG MSMEG_6892|M.smegmatis_MC2_155 PIRYASIDEGNLLAVETAAEHFGVTPIRDEYAAAQVTTLRLPAPYRLTRG TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV Rv0058|M.tuberculosis_H37Rv RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV MSMEG_6892|M.smegmatis_MC2_155 KRNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLRHLWATDGSV TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR Rv0058|M.tuberculosis_H37Rv RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR MSMEG_6892|M.smegmatis_MC2_155 RWDAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAKKAGYRDCWH TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW Rv0058|M.tuberculosis_H37Rv LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW MSMEG_6892|M.smegmatis_MC2_155 VLIYGRENQKRFVAHVGVHGARGAAARDLLAELESVTQDTNLDTVPKEVW TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR Rv0058|M.tuberculosis_H37Rv AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR MSMEG_6892|M.smegmatis_MC2_155 SQVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLHRAASLLEDA TH_1409|M.thermoresistible__bu -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK ----------------------------------------------SIEQ Mvan_6030|M.vanbaalenii_PYR-1 ----------------------------------------------SIEQ MAV_0079|M.avium_104 ----------------------------------------------SLEQ MMAR_0076|M.marinum_M ----------------------------------------------SLEQ MLBr_02680|M.leprae_Br4923 ----------------------------------------------SLEQ MUL_0075|M.ulcerans_Agy99 ----------------------------------------------SLEQ MAB_4895c|M.abscessus_ATCC_199 ----------------------------------------------SLEQ Mb0059|M.bovis_AF2122/97 AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ Rv0058|M.tuberculosis_H37Rv AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ MSMEG_6892|M.smegmatis_MC2_155 ALHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQGISAHNSLEQ TH_1409|M.thermoresistible__bu ----------------------------------------------SLEQ *:** Mflv_0878|M.gilvum_PYR-GCK DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTVTVAHQLHLSRF Mvan_6030|M.vanbaalenii_PYR-1 DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTITVAHQLHLSRF MAV_0079|M.avium_104 DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF MMAR_0076|M.marinum_M DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF MLBr_02680|M.leprae_Br4923 DADVVILLHRPDAFDRDDPRGGEADLILAKHRNGPTKTVTVAHQLHLSRF MUL_0075|M.ulcerans_Agy99 DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF MAB_4895c|M.abscessus_ATCC_199 DADMVILLHRPDAFERDDPRGGEADLILGKHRNGPTATITVAHQLHLSRF Mb0059|M.bovis_AF2122/97 DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF Rv0058|M.tuberculosis_H37Rv DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF MSMEG_6892|M.smegmatis_MC2_155 DADMVMLLHRPDAFDRDDPRGGEADIILGKHRNGPTANITVAHQLHFSRF TH_1409|M.thermoresistible__bu DADMVILLHRPDAFDRDDPRGGEADLILGKHRNGPTKTITVAHQLHLSRF ***:*:**:*****: *********:*:.*** *** .:*******:*** Mflv_0878|M.gilvum_PYR-GCK SNMAK Mvan_6030|M.vanbaalenii_PYR-1 SNMAK MAV_0079|M.avium_104 ANMAR MMAR_0076|M.marinum_M ANMAR MLBr_02680|M.leprae_Br4923 TNMAR MUL_0075|M.ulcerans_Agy99 ANMAR MAB_4895c|M.abscessus_ATCC_199 TNMAR Mb0059|M.bovis_AF2122/97 ANMAR Rv0058|M.tuberculosis_H37Rv ANMAR MSMEG_6892|M.smegmatis_MC2_155 TNMAR TH_1409|M.thermoresistible__bu ANMAK :***: