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M. thermoresistible (build 8) TH_1409 (dnaB)

annotation: PROBABLE REPLICATIVE DNA HELICASE DNAB
coordinates: 2661492 - 2662571
length: 360

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1409dnaB-100% (360)PROBABLE REPLICATIVE DNA HELICASE DNAB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0059dnaB1e-12160.45% (359) replicative DNA helicase
M. gilvum PYR-GCKMflv_0878-4e-2584.75% (59) DnaB domain-containing protein
M. tuberculosis H37RvRv0058dnaB1e-12160.45% (359) replicative DNA helicase
M. leprae Br4923MLBr_02680dnaB1e-2791.53% (59) replicative DNA helicase
M. abscessus ATCC 19977MAB_4895c-2e-2793.22% (59) replicative DNA helicase
M. marinum MMMAR_0076dnaB3e-2689.83% (59) replicative DNA helicase DnaB
M. avium 104MAV_0079-2e-2689.83% (59) replicative DNA helicase
M. smegmatis MC2 155MSMEG_6892-1e-15169.64% (359) replicative DNA helicase
M. ulcerans Agy99MUL_0075dnaB2e-2689.83% (59) replicative DNA helicase DnaB
M. vanbaalenii PYR-1Mvan_6030-4e-2586.44% (59) DnaB domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0878|M.gilvum_PYR-GCK          MAVVDDRGR-SGDRSDLEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV
Mvan_6030|M.vanbaalenii_PYR-1       ----------------MEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAV
MAV_0079|M.avium_104                MAVVDDLTS-GMD----SSSPSEDFGRQPPQDLAAEQAVLGGMLLSKDAI
MMAR_0076|M.marinum_M               MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV
MLBr_02680|M.leprae_Br4923          MAVVDDLAH-SGMD---AVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAI
MUL_0075|M.ulcerans_Agy99           MAVVDDLAH-SDN--MDAPPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAV
MAB_4895c|M.abscessus_ATCC_199      MAIVDDLGQ-SGP----AAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDAI
Mb0059|M.bovis_AF2122/97            MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI
Rv0058|M.tuberculosis_H37Rv         MAVVDDLAP-GMD----SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAI
MSMEG_6892|M.smegmatis_MC2_155      ---MDDLGHPDGPADIDGPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDAI
TH_1409|M.thermoresistible__bu      ------VRR--------QPVRYAGTDEWNLQALSTAARRFGVTAVRDDHA
                                                           . ..   *  ::    :*   : .*  

Mflv_0878|M.gilvum_PYR-GCK          ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR
Mvan_6030|M.vanbaalenii_PYR-1       ADVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLR
MAV_0079|M.avium_104                ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRNLLR
MMAR_0076|M.marinum_M               ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR
MLBr_02680|M.leprae_Br4923          ADVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
MUL_0075|M.ulcerans_Agy99           ADVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLR
MAB_4895c|M.abscessus_ATCC_199      ADVLEKLRPHDFYRPNHQSVYEAILDLYGRGEPADAVTVAAELDRRGQLR
Mb0059|M.bovis_AF2122/97            ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
Rv0058|M.tuberculosis_H37Rv         ADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLR
MSMEG_6892|M.smegmatis_MC2_155      ADVLERLRPGDFYRPAHQSVYDAILDLYGRGEPADAVTVAAELDRRGLLR
TH_1409|M.thermoresistible__bu      AARVTTLRLPAPYRLTHG----------------TRDPIAAWLDRLGLFG
                                    *  :  **    *:  :                    .:** *** . : 

Mflv_0878|M.gilvum_PYR-GCK          RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA
Mvan_6030|M.vanbaalenii_PYR-1       RVGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYA
MAV_0079|M.avium_104                RIGGAPYLHTLISTVPTAANAGYYATIVAEKALLRRLVEAGTRVVQYGYA
MMAR_0076|M.marinum_M               RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA
MLBr_02680|M.leprae_Br4923          RIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA
MUL_0075|M.ulcerans_Agy99           RIGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYA
MAB_4895c|M.abscessus_ATCC_199      RVGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYA
Mb0059|M.bovis_AF2122/97            RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA
Rv0058|M.tuberculosis_H37Rv         RIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYA
MSMEG_6892|M.smegmatis_MC2_155      RIGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRVVQYGYA
TH_1409|M.thermoresistible__bu      KSGHEKFVPAEVFRLPNDQIA----------LFLRHLWATDGSVRWDGRA
                                    : *   :: : :  :*.   *           :**:*  :.  *   * *

Mflv_0878|M.gilvum_PYR-GCK          GADGADVNEIVDRAQAEIYDVTERKSSEDYVILEEILQPAMDEIDAIASQ
Mvan_6030|M.vanbaalenii_PYR-1       GADGADVNEIVDRAQAEIYDVTERKSSEDFVILEEILQPAMDEIDAIASE
MAV_0079|M.avium_104                GAEGADVAEVVDRAQAEIYEVAERRTTEDFVPLEDLLQPTMDEIDAIASN
MMAR_0076|M.marinum_M               GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN
MLBr_02680|M.leprae_Br4923          GAEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIASN
MUL_0075|M.ulcerans_Agy99           GAEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASN
MAB_4895c|M.abscessus_ATCC_199      GAEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIASA
Mb0059|M.bovis_AF2122/97            GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS
Rv0058|M.tuberculosis_H37Rv         GAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASS
MSMEG_6892|M.smegmatis_MC2_155      GADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQ
TH_1409|M.thermoresistible__bu      GQG------------RIYYASTSRRVVDDVMLLLLRLG--------IAAR
                                    *                 *  :. :  :: : *   *         **: 

Mflv_0878|M.gilvum_PYR-GCK          GGISKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG
Mvan_6030|M.vanbaalenii_PYR-1       GGVSKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTG
MAV_0079|M.avium_104                GGVARGVPTGFTELDEVTNGLHAGQMIIVAARPGVGKALALDTPLPTPTG
MMAR_0076|M.marinum_M               GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG--------------
MLBr_02680|M.leprae_Br4923          GGISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPTG
MUL_0075|M.ulcerans_Agy99           GGISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVG--------------
MAB_4895c|M.abscessus_ATCC_199      GGISKGVPTGFTDLDEITNGLHPGQMIIVAARPGVG--------------
Mb0059|M.bovis_AF2122/97            GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG--------------
Rv0058|M.tuberculosis_H37Rv         GGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG--------------
MSMEG_6892|M.smegmatis_MC2_155      GGIARGVPTGFTELDEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPSG
TH_1409|M.thermoresistible__bu      --IKRVTKARFRDS---------WHLVIHGAENQLR--------------
                                      : : . : * :           :::: .*.  :               

Mflv_0878|M.gilvum_PYR-GCK          WTTMAEVKVGDFLIGADGKPTRVVAATNVMVDRPCFEVEFSDGTVLVADA
Mvan_6030|M.vanbaalenii_PYR-1       WTTMADVAVGDLLIGADGKPTRVVAATEVMVGRPCYEVEFSDGTVIVADA
MAV_0079|M.avium_104                WTTMGDVAVGDELLGDDGRPTRVVAATDVMLGRPCYEVEFSDGTVIVADA
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          WTAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVADA
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      WTTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRPCYVVEFSDGTAIVADA
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          EHQWLTETRASRKSAQAAAVGYNRTKNQRTFAAVRTTREIAETLRCPTVD
Mvan_6030|M.vanbaalenii_PYR-1       EHQWLTETRASRKSAQAAAVGYNRYKNQRTFAAVRTTREIGETLRCPTAD
MAV_0079|M.avium_104                AHQWLTETRVSRKSAQAAAVGYNRYKNQRTFAAVRTTAEIAETLRCPAQD
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          QHQWPTSYG-----------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      QHQWPTEHG-----------------------------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          RRLNHSIVNTAPIQGVEKDLLVPPYTLGAWLGDGTSAAAQITTADPEVLM
Mvan_6030|M.vanbaalenii_PYR-1       RRLNHSVVNAAPIEAPVADLLLPPYTLGAWLGDGTSRAAQITTADPEILM
MAV_0079|M.avium_104                RRLNHSVVNARALELPDREFLVPPYTLGAWLGDGTSAAAQITAADPEIIM
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      --------------------------------------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          RIEGEGLVTVPSKSAKMRYQILLPEAEPTGVRSCAVCGQDFVPQTSQVRT
Mvan_6030|M.vanbaalenii_PYR-1       RIEAEGLVTVPLPGARMRYGLQLPTEAPAGTRECVVCGASFTPSTSQVRT
MAV_0079|M.avium_104                RIEAE---------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      --------------------------------------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          CGRSCGGRVRFLTDPVPAPTCATCGGPSCGLRMCKSCRGAFGSVQARLRT
Mvan_6030|M.vanbaalenii_PYR-1       CGRSCGGRARFVSEPVAAPTCSHCGGPSCGLRLCQSCRNAVGTVQGRLRT
MAV_0079|M.avium_104                -----------------------------------DSGAGVGTLQARLRT
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      --------------------------------------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          IGVLGAKHIPIDYLRASEEQRRALLAGLLDTDGTVPNGGSVQYTGTNARL
Mvan_6030|M.vanbaalenii_PYR-1       IGVLGNKHIPTEYLRASEAQRRALLAGLLDTDGTVTNGGAVQFSVTSRRL
MAV_0079|M.avium_104                IGVLGNKHIPTEYLRGSEAQRRALLAGLLDTDGTVTVGGAVQFSVTNQRL
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      --------------------------------------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          IGDVAELVVSLGYRCQIAKKAVNGRSADSSVAYTINFSTDDVVFGLHRKA
Mvan_6030|M.vanbaalenii_PYR-1       AADVAELVVSLGYRCQVATKAVKGRTEASSTAYILNFSTTDSVFGLHRKD
MAV_0079|M.avium_104                ARDVNELIVSLGYRCQTSTKRVQGRSETSSIAYTLTFSTADKVFALERKA
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          ------IRTSAQLRCGLDIIAAAGSTP-----------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      ----VRITANLRAGMHTVVSASGGRGG-----------------------
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          VLHKERRRSASTVRSGSRFITDVRPVPSVPVRCVEVDNDDHLYLAGRSMI
Mvan_6030|M.vanbaalenii_PYR-1       LSHKERR-SKSSVRSNTRFIVDVREIETVPVRCVEVDNDDHMYLASRSMI
MAV_0079|M.avium_104                IAHKERRAVTGTSRGGSRFIVDVRPIEPVAVRCVEVDNDSHMYLASRAMV
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --RHAGRLTTAAFMAPVLCIDSVRRVRSVPVRCVEVDNAAHLYLAGRGMV
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            --------------------------------------------------
Rv0058|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_6892|M.smegmatis_MC2_155      ----------TALLAPAVQITAVRRRPSVPVRCVEVDNPEHLYLAGPGMV
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          PTHNSTLGLDFMRSCSIKHQLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD
Mvan_6030|M.vanbaalenii_PYR-1       PTHNSTLGLDFMRSCSIKHHLPSIVFSLEMSKTEIVMRLLSAEAKIKLAD
MAV_0079|M.avium_104                PTHNSTLGLDFLRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
MMAR_0076|M.marinum_M               ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD
MLBr_02680|M.leprae_Br4923          PTHNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKLAD
MUL_0075|M.ulcerans_Agy99           ---KSTLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLAD
MAB_4895c|M.abscessus_ATCC_199      ---KSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKLGD
Mb0059|M.bovis_AF2122/97            ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
Rv0058|M.tuberculosis_H37Rv         ---KSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSD
MSMEG_6892|M.smegmatis_MC2_155      PTHNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLGD
TH_1409|M.thermoresistible__bu      ----------FLRHVGVKG-LEDVAAQTVITKLERVVRNPDVDT------
                                              *:*  .::  : .:  .  ::* * *:*  ..::      

Mflv_0878|M.gilvum_PYR-GCK          MRSGRMNDDDWTKLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA
Mvan_6030|M.vanbaalenii_PYR-1       MRSGRMNDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKA
MAV_0079|M.avium_104                MRSGRMSDEDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA
MMAR_0076|M.marinum_M               MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKA
MLBr_02680|M.leprae_Br4923          MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKT
MUL_0075|M.ulcerans_Agy99           MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTTMEIRAKARRLRQKA
MAB_4895c|M.abscessus_ATCC_199      MRSGRMSDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLNQKA
Mb0059|M.bovis_AF2122/97            MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA
Rv0058|M.tuberculosis_H37Rv         MRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKA
MSMEG_6892|M.smegmatis_MC2_155      MRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKS
TH_1409|M.thermoresistible__bu      -----VPTNVWTRVRQALADK-----RIIHREIAAAMGTQFSGSALWKRA
                                         :  : **:: : :::       * .    : *  : ..  * :::

Mflv_0878|M.gilvum_PYR-GCK          DLRLIVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL
Mvan_6030|M.vanbaalenii_PYR-1       DLRLVVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQL
MAV_0079|M.avium_104                DLRLVVVDYLQLMSSGKKVESRQLEVSEFSRQLKLLAKELEVPVVAISQL
MMAR_0076|M.marinum_M               NLKLVVVDYLQLMTSGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL
MLBr_02680|M.leprae_Br4923          NLKLVVVDYLQLMTSGKRFESRQVEVSEFSRHLKLLAKELELPVVAISQL
MUL_0075|M.ulcerans_Agy99           NLKLVVVDYLQLMISGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQL
MAB_4895c|M.abscessus_ATCC_199      GLKLVVVDYLQLMTSGKKHESRQQEVSEFSRNLKLLAKELEVPVIAISQL
Mb0059|M.bovis_AF2122/97            NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL
Rv0058|M.tuberculosis_H37Rv         NLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQL
MSMEG_6892|M.smegmatis_MC2_155      DLRLIVVDYMQLMTSGKKYESRQQEVSDFSRSLKLMAKELDVPVVAISQL
TH_1409|M.thermoresistible__bu      PSRDRLHRIAALLEDRERHDTATDDVHWDT----------LVEITSIGEH
                                      :  :     *: . :: ::   :*   :           : : ::.: 

Mflv_0878|M.gilvum_PYR-GCK          NRGPEQRTDKKPMLSDLRESG-----------------------------
Mvan_6030|M.vanbaalenii_PYR-1       NRGPEQRTDKKPMLSDLRESG-----------------------------
MAV_0079|M.avium_104                NRGPEQRTDKKPMLSDLRESG-----------------------------
MMAR_0076|M.marinum_M               NRGPEQRTDKKPMLSDLRESG-----------------------------
MLBr_02680|M.leprae_Br4923          NRSPEQRTDKKPMLSDLRESG-----------------------------
MUL_0075|M.ulcerans_Agy99           NRGPEQRTDKKPMLSDLRESG-----------------------------
MAB_4895c|M.abscessus_ATCC_199      NRGPEQRTDKRPQVSDLRESG-----------------------------
Mb0059|M.bovis_AF2122/97            NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP
Rv0058|M.tuberculosis_H37Rv         NRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERP
MSMEG_6892|M.smegmatis_MC2_155      NRGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFGELMATGERP
TH_1409|M.thermoresistible__bu      DVYDATVPGTHNFVANAVSLHN----------------------------
                                    :      ...:  :::  .                               

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE
Rv0058|M.tuberculosis_H37Rv         MVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFE
MSMEG_6892|M.smegmatis_MC2_155      LVWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEATANHPFLTLD
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ
Rv0058|M.tuberculosis_H37Rv         GWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQ
MSMEG_6892|M.smegmatis_MC2_155      GWVPLGELKPGDRLATPRLVPEPVNTQRMHDSEVVMLAHMIGDGSCVKRQ
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            PIRYEPVDEANLAAVTVSAAHSDGAAIRDDYLAARVPSL-RPARQRLPRG
Rv0058|M.tuberculosis_H37Rv         PIRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPSL-RPARQRLPRG
MSMEG_6892|M.smegmatis_MC2_155      PIRYASIDEGNLLAVETAAEHFGVTPIRDEYAAAQVTTLRLPAPYRLTRG
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV
Rv0058|M.tuberculosis_H37Rv         RCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSV
MSMEG_6892|M.smegmatis_MC2_155      KRNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLRHLWATDGSV
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR
Rv0058|M.tuberculosis_H37Rv         RWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWR
MSMEG_6892|M.smegmatis_MC2_155      RWDAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAKKAGYRDCWH
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW
Rv0058|M.tuberculosis_H37Rv         LHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVW
MSMEG_6892|M.smegmatis_MC2_155      VLIYGRENQKRFVAHVGVHGARGAAARDLLAELESVTQDTNLDTVPKEVW
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_6030|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_0079|M.avium_104                --------------------------------------------------
MMAR_0076|M.marinum_M               --------------------------------------------------
MLBr_02680|M.leprae_Br4923          --------------------------------------------------
MUL_0075|M.ulcerans_Agy99           --------------------------------------------------
MAB_4895c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0059|M.bovis_AF2122/97            AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR
Rv0058|M.tuberculosis_H37Rv         AQVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDR
MSMEG_6892|M.smegmatis_MC2_155      SQVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLHRAASLLEDA
TH_1409|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0878|M.gilvum_PYR-GCK          ----------------------------------------------SIEQ
Mvan_6030|M.vanbaalenii_PYR-1       ----------------------------------------------SIEQ
MAV_0079|M.avium_104                ----------------------------------------------SLEQ
MMAR_0076|M.marinum_M               ----------------------------------------------SLEQ
MLBr_02680|M.leprae_Br4923          ----------------------------------------------SLEQ
MUL_0075|M.ulcerans_Agy99           ----------------------------------------------SLEQ
MAB_4895c|M.abscessus_ATCC_199      ----------------------------------------------SLEQ
Mb0059|M.bovis_AF2122/97            AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ
Rv0058|M.tuberculosis_H37Rv         AIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQ
MSMEG_6892|M.smegmatis_MC2_155      ALHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQGISAHNSLEQ
TH_1409|M.thermoresistible__bu      ----------------------------------------------SLEQ
                                                                                  *:**

Mflv_0878|M.gilvum_PYR-GCK          DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTVTVAHQLHLSRF
Mvan_6030|M.vanbaalenii_PYR-1       DADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTITVAHQLHLSRF
MAV_0079|M.avium_104                DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MMAR_0076|M.marinum_M               DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MLBr_02680|M.leprae_Br4923          DADVVILLHRPDAFDRDDPRGGEADLILAKHRNGPTKTVTVAHQLHLSRF
MUL_0075|M.ulcerans_Agy99           DADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MAB_4895c|M.abscessus_ATCC_199      DADMVILLHRPDAFERDDPRGGEADLILGKHRNGPTATITVAHQLHLSRF
Mb0059|M.bovis_AF2122/97            DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
Rv0058|M.tuberculosis_H37Rv         DADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRF
MSMEG_6892|M.smegmatis_MC2_155      DADMVMLLHRPDAFDRDDPRGGEADIILGKHRNGPTANITVAHQLHFSRF
TH_1409|M.thermoresistible__bu      DADMVILLHRPDAFDRDDPRGGEADLILGKHRNGPTKTITVAHQLHLSRF
                                    ***:*:**:*****: *********:*:.*** *** .:*******:***

Mflv_0878|M.gilvum_PYR-GCK          SNMAK
Mvan_6030|M.vanbaalenii_PYR-1       SNMAK
MAV_0079|M.avium_104                ANMAR
MMAR_0076|M.marinum_M               ANMAR
MLBr_02680|M.leprae_Br4923          TNMAR
MUL_0075|M.ulcerans_Agy99           ANMAR
MAB_4895c|M.abscessus_ATCC_199      TNMAR
Mb0059|M.bovis_AF2122/97            ANMAR
Rv0058|M.tuberculosis_H37Rv         ANMAR
MSMEG_6892|M.smegmatis_MC2_155      TNMAR
TH_1409|M.thermoresistible__bu      ANMAK
                                    :***: