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DDLGHPDGPADIDGPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDAIADVLERLRPGDFYRPAHQSVYDAI LDLYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRV VQYGYAGADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQGGIARGVPTGFTEL DEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPSGWTTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRP CYVVEFSDGTAIVADAQHQWPTEHGVRITANLRAGMHTVVSASGGRGGTALLAPAVQITAVRRRPSVPVR CVEVDNPEHLYLAGPGMVPTHNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLGDMR SGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKSDLRLIVVDYMQLMTSGKKYESR QQEVSDFSRSLKLMAKELDVPVVAISQLNRGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFGE LMATGERPLVWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEATANHPFLTLDGWVPLGELKPGD RLATPRLVPEPVNTQRMHDSEVVMLAHMIGDGSCVKRQPIRYASIDEGNLLAVETAAEHFGVTPIRDEYA AAQVTTLRLPAPYRLTRGKRNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLRHLWATDGSVRW DAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAKKAGYRDCWHVLIYGRENQKRFVAHVGVHGAR GAAARDLLAELESVTQDTNLDTVPKEVWSQVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLHR AASLLEDAALHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQGISAHNSLEQDADMVMLLHRPD AFDRDDPRGGEADIILGKHRNGPTANITVAHQLHFSRFTNMAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6892 | - | - | 100% (1024) | replicative DNA helicase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0059 | dnaB | 0.0 | 68.79% (676) | replicative DNA helicase |
M. gilvum PYR-GCK | Mflv_0878 | - | 1e-144 | 81.58% (304) | DnaB domain-containing protein |
M. tuberculosis H37Rv | Rv0058 | dnaB | 0.0 | 68.79% (676) | replicative DNA helicase |
M. leprae Br4923 | MLBr_02680 | dnaB | 0.0 | 80.36% (555) | replicative DNA helicase |
M. abscessus ATCC 19977 | MAB_4895c | - | 1e-111 | 84.17% (240) | replicative DNA helicase |
M. marinum M | MMAR_0076 | dnaB | 1e-118 | 87.92% (240) | replicative DNA helicase DnaB |
M. avium 104 | MAV_0079 | - | 1e-151 | 87.83% (304) | replicative DNA helicase |
M. thermoresistible (build 8) | TH_2096 | dnaB | 0.0 | 88.99% (572) | PROBABLE REPLICATIVE DNA HELICASE DNAB |
M. ulcerans Agy99 | MUL_0075 | dnaB | 1e-118 | 87.92% (240) | replicative DNA helicase DnaB |
M. vanbaalenii PYR-1 | Mvan_6030 | - | 1e-144 | 85.47% (289) | DnaB domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6892|M.smegmatis_MC2_155 --MDDLGHPDGPADIDGPPPSGDFGRQPPQDMAAEQAVLGGMLLSKDAIA TH_2096|M.thermoresistible__bu -----------------------------------------MLLSKDAIA MLBr_02680|M.leprae_Br4923 ---MAVVDDLAHSGMDAVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAIA Mb0059|M.bovis_AF2122/97 MAVVDDLAP--GMD--SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAIA Rv0058|M.tuberculosis_H37Rv MAVVDDLAP--GMD--SSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAIA MMAR_0076|M.marinum_M MAVVDDLAHSDNMD--APPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAVA MUL_0075|M.ulcerans_Agy99 MAVVDDLAHSDNMD--APPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAVA Mflv_0878|M.gilvum_PYR-GCK MAVVDDRGRSGDRSDLEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAVA Mvan_6030|M.vanbaalenii_PYR-1 ---------------MEPPPSEDFGRQPPQDAAAEQAVLGGMLLSKDAVA MAV_0079|M.avium_104 MAVVDDLTSGMD----SSSPSEDFGRQPPQDLAAEQAVLGGMLLSKDAIA MAB_4895c|M.abscessus_ATCC_199 MAIVDDLGQSGP----AAPPEEDFGRQPPQDVAAEQSVLGGMMLSKDAIA *:*****:* MSMEG_6892|M.smegmatis_MC2_155 DVLERLRPGDFYRPAHQSVYDAILDLYGRGEPADAVTVAAELDRRGLLRR TH_2096|M.thermoresistible__bu DVLEKLRPGDFYKPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRR MLBr_02680|M.leprae_Br4923 DVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRR Mb0059|M.bovis_AF2122/97 DVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRR Rv0058|M.tuberculosis_H37Rv DVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRR MMAR_0076|M.marinum_M DVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLRR MUL_0075|M.ulcerans_Agy99 DVLERLRPGDFYRPAHQNIYDAILDLYGRGEPADAVTVAAELDRRGLLRR Mflv_0878|M.gilvum_PYR-GCK DVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLRR Mvan_6030|M.vanbaalenii_PYR-1 DVLEKLRPGDFYKPANQLVYDAILDLYGRGEPADAVTVAAELDRRGLLRR MAV_0079|M.avium_104 DVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRNLLRR MAB_4895c|M.abscessus_ATCC_199 DVLEKLRPHDFYRPNHQSVYEAILDLYGRGEPADAVTVAAELDRRGQLRR ****:**. ***:* :* :*:************************. *** MSMEG_6892|M.smegmatis_MC2_155 IGGAPYLHTLISTVPTAANAGFYAGIVAEKALLRRLVEAGTRVVQYGYAG TH_2096|M.thermoresistible__bu IGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYAG MLBr_02680|M.leprae_Br4923 IGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYAG Mb0059|M.bovis_AF2122/97 IGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYAG Rv0058|M.tuberculosis_H37Rv IGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYAG MMAR_0076|M.marinum_M IGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYAG MUL_0075|M.ulcerans_Agy99 IGGAPYLHTLISTVPTAANAGYYAGIVGEKALLRRLVEAGTRVVQYGYAG Mflv_0878|M.gilvum_PYR-GCK VGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYAG Mvan_6030|M.vanbaalenii_PYR-1 VGGAPYLHTLISTVPTAANAGYYAEIVAEKSLLRRLVEAGTRVVQYGYAG MAV_0079|M.avium_104 IGGAPYLHTLISTVPTAANAGYYATIVAEKALLRRLVEAGTRVVQYGYAG MAB_4895c|M.abscessus_ATCC_199 VGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYAG :********************:** **.**:******************* MSMEG_6892|M.smegmatis_MC2_155 ADGADVADIVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQG TH_2096|M.thermoresistible__bu ADGADVNEVVDRAQAEIYDVTERRASEDFVPLEDLLQPTMDEIDAIASQG MLBr_02680|M.leprae_Br4923 AEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIASNG Mb0059|M.bovis_AF2122/97 AEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSG Rv0058|M.tuberculosis_H37Rv AEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSG MMAR_0076|M.marinum_M AEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASNG MUL_0075|M.ulcerans_Agy99 AEGADVAEVVDRAQAEIYDVADRRLSEDFVPLEDLLQPTMDEIDAIASNG Mflv_0878|M.gilvum_PYR-GCK ADGADVNEIVDRAQAEIYDVTERKSSEDYVILEEILQPAMDEIDAIASQG Mvan_6030|M.vanbaalenii_PYR-1 ADGADVNEIVDRAQAEIYDVTERKSSEDFVILEEILQPAMDEIDAIASEG MAV_0079|M.avium_104 AEGADVAEVVDRAQAEIYEVAERRTTEDFVPLEDLLQPTMDEIDAIASNG MAB_4895c|M.abscessus_ATCC_199 AEGADVAEVVDRAQAEVYDVTDRRMSEDYVPLEELLQPTMDEIDAIASAG *:**** ::*******:*:*:: : :*::* **::***:**::***** * MSMEG_6892|M.smegmatis_MC2_155 GIARGVPTGFTELDEVTNGLHAGQMIIIAARPGVGKALALDTPLPTPSGW TH_2096|M.thermoresistible__bu GLARGVPTGFIELDEVTNGLHPGQMIIIAARPGVGKALALDTPLPTPHGW MLBr_02680|M.leprae_Br4923 GISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPTGW Mb0059|M.bovis_AF2122/97 GLARGVATGFTELDEVTNGLHPGQMVIVAARPGVGK-------------- Rv0058|M.tuberculosis_H37Rv GLARGVATGFTELDEVTNGLHPGQMVIVAARPGVGK-------------- MMAR_0076|M.marinum_M GISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVGK-------------- MUL_0075|M.ulcerans_Agy99 GISRGVPTGFTELDEVTNGLHPGQMIIVAARPGVGK-------------- Mflv_0878|M.gilvum_PYR-GCK GISKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTGW Mvan_6030|M.vanbaalenii_PYR-1 GVSKGVPTGFTDLDELTNGLHPGQMIVVAARPGMGKALALDTPLPTPTGW MAV_0079|M.avium_104 GVARGVPTGFTELDEVTNGLHAGQMIIVAARPGVGKALALDTPLPTPTGW MAB_4895c|M.abscessus_ATCC_199 GISKGVPTGFTDLDEITNGLHPGQMIIVAARPGVG--------------- *:::*..*** :***:*****.***:::*****:* MSMEG_6892|M.smegmatis_MC2_155 TTMGDVAVGDHLLGPDGEPTRVVADTDVMLGRPCYVVEFSDGTAIVADAQ TH_2096|M.thermoresistible__bu TTMGDVAVGDELLGADGRPTRVVAATEVMLGRPCYEVEFSDGTVIVADAD MLBr_02680|M.leprae_Br4923 TAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVADAQ Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK TTMAEVKVGDFLIGADGKPTRVVAATNVMVDRPCFEVEFSDGTVLVADAE Mvan_6030|M.vanbaalenii_PYR-1 TTMADVAVGDLLIGADGKPTRVVAATEVMVGRPCYEVEFSDGTVIVADAE MAV_0079|M.avium_104 TTMGDVAVGDELLGDDGRPTRVVAATDVMLGRPCYEVEFSDGTVIVADAA MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 HQWPTEHGVRITANLRAGMHTVVSAS------------------------ TH_2096|M.thermoresistible__bu HQWPTGYGVRTTARLRAGLDTIAAAG------------------------ MLBr_02680|M.leprae_Br4923 HQWPTSYGIRTSAQLRCGLDIIAAAG------------------------ Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK HQWLTETRASRKSAQAAAVGYNRTKNQRTFAAVRTTREIAETLRCPTVDR Mvan_6030|M.vanbaalenii_PYR-1 HQWLTETRASRKSAQAAAVGYNRYKNQRTFAAVRTTREIGETLRCPTADR MAV_0079|M.avium_104 HQWLTETRVSRKSAQAAAVGYNRYKNQRTFAAVRTTAEIAETLRCPAQDR MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK RLNHSIVNTAPIQGVEKDLLVPPYTLGAWLGDGTSAAAQITTADPEVLMR Mvan_6030|M.vanbaalenii_PYR-1 RLNHSVVNAAPIEAPVADLLLPPYTLGAWLGDGTSRAAQITTADPEILMR MAV_0079|M.avium_104 RLNHSVVNARALELPDREFLVPPYTLGAWLGDGTSAAAQITAADPEIIMR MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK IEGEGLVTVPSKSAKMRYQILLPEAEPTGVRSCAVCGQDFVPQTSQVRTC Mvan_6030|M.vanbaalenii_PYR-1 IEAEGLVTVPLPGARMRYGLQLPTEAPAGTRECVVCGASFTPSTSQVRTC MAV_0079|M.avium_104 IEAE---------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK GRSCGGRVRFLTDPVPAPTCATCGGPSCGLRMCKSCRGAFGSVQARLRTI Mvan_6030|M.vanbaalenii_PYR-1 GRSCGGRARFVSEPVAAPTCSHCGGPSCGLRLCQSCRNAVGTVQGRLRTI MAV_0079|M.avium_104 ----------------------------------DSGAGVGTLQARLRTI MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 -------------------------------------------------- TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK GVLGAKHIPIDYLRASEEQRRALLAGLLDTDGTVPNGGSVQYTGTNARLI Mvan_6030|M.vanbaalenii_PYR-1 GVLGNKHIPTEYLRASEAQRRALLAGLLDTDGTVTNGGAVQFSVTSRRLA MAV_0079|M.avium_104 GVLGNKHIPTEYLRGSEAQRRALLAGLLDTDGTVTVGGAVQFSVTNQRLA MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 ------------------------------------------------GG TH_2096|M.thermoresistible__bu ------------------------------------------------SM MLBr_02680|M.leprae_Br4923 ------------------------------------------------ST Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK GDVAELVVSLGYRCQIAKKAVNGRSADSSVAYTINFSTDDVVFGLHRKAV Mvan_6030|M.vanbaalenii_PYR-1 ADVAELVVSLGYRCQVATKAVKGRTEASSTAYILNFSTTDSVFGLHRKDL MAV_0079|M.avium_104 RDVNELIVSLGYRCQTSTKRVQGRSETSSIAYTLTFSTADKVFALERKAI MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 R------GGTALLAPAVQITAVRRRPSVPVRCVEVDNPEHLYLAGPGMVP TH_2096|M.thermoresistible__bu ARYGEQPGGAALLAPVLQIDAVRRINSVPVRCVEVDNPAHLYLAGQGMVP MLBr_02680|M.leprae_Br4923 PRHAGRLTTAAFMAPVLCIDSVRRVRSVPVRCVEVDNAAHLYLAGRGMVP Mb0059|M.bovis_AF2122/97 -------------------------------------------------- Rv0058|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK LHKERRRSASTVRSGSRFITDVRPVPSVPVRCVEVDNDDHLYLAGRSMIP Mvan_6030|M.vanbaalenii_PYR-1 SHKERR-SKSSVRSNTRFIVDVREIETVPVRCVEVDNDDHMYLASRSMIP MAV_0079|M.avium_104 AHKERRAVTGTSRGGSRFIVDVRPIEPVAVRCVEVDNDSHMYLASRAMVP MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 THNSTLGLDFMRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLGDM TH_2096|M.thermoresistible__bu THNSTLGLDFMRSCSIKHRMASIIFSLEMSKSEIVMRLLSAEAKIKLSDM MLBr_02680|M.leprae_Br4923 THNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKLADM Mb0059|M.bovis_AF2122/97 ---STLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSDM Rv0058|M.tuberculosis_H37Rv ---STLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSDM MMAR_0076|M.marinum_M ---STLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLADM MUL_0075|M.ulcerans_Agy99 ---STLGLDFMRSCSIKHQMASVIFSLEMSKTEIVMRLLSAEAKIKLADM Mflv_0878|M.gilvum_PYR-GCK THNSTLGLDFMRSCSIKHQLPSIVFSLEMSKTEIVMRLLSAEAKIKLADM Mvan_6030|M.vanbaalenii_PYR-1 THNSTLGLDFMRSCSIKHHLPSIVFSLEMSKTEIVMRLLSAEAKIKLADM MAV_0079|M.avium_104 THNSTLGLDFLRSCSIKHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSDM MAB_4895c|M.abscessus_ATCC_199 --KSTLGLDFMRSCSIKHQLPSVIFSLEMSKTEIVMRLLSAEAKIKLGDM *******:*****:*::.*::*******:***************.** MSMEG_6892|M.smegmatis_MC2_155 RSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKSD TH_2096|M.thermoresistible__bu RSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLAQKAD MLBr_02680|M.leprae_Br4923 RSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKTN Mb0059|M.bovis_AF2122/97 RSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKAN Rv0058|M.tuberculosis_H37Rv RSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKAN MMAR_0076|M.marinum_M RSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKAN MUL_0075|M.ulcerans_Agy99 RSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTTMEIRAKARRLRQKAN Mflv_0878|M.gilvum_PYR-GCK RSGRMNDDDWTKLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKAD Mvan_6030|M.vanbaalenii_PYR-1 RSGRMNDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLKQKAD MAV_0079|M.avium_104 RSGRMSDEDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKAD MAB_4895c|M.abscessus_ATCC_199 RSGRMSDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLNQKAG *****.*:***:*************:******** ********** **:. MSMEG_6892|M.smegmatis_MC2_155 LRLIVVDYMQLMTSGKKYESRQQEVSDFSRSLKLMAKELDVPVVAISQLN TH_2096|M.thermoresistible__bu LRLVVVDYMQLMTSGKKYESRQQEVSDFSRSLKLMAKELDLPVVAISQLN MLBr_02680|M.leprae_Br4923 LKLVVVDYLQLMTSGKRFESRQVEVSEFSRHLKLLAKELELPVVAISQLN Mb0059|M.bovis_AF2122/97 LKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLN Rv0058|M.tuberculosis_H37Rv LKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLN MMAR_0076|M.marinum_M LKLVVVDYLQLMTSGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQLN MUL_0075|M.ulcerans_Agy99 LKLVVVDYLQLMISGKKHESRQVEVSEFSRHLKLLAKEIEVPVVAISQLN Mflv_0878|M.gilvum_PYR-GCK LRLIVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQLN Mvan_6030|M.vanbaalenii_PYR-1 LRLVVIDYLQLMTSGKKVESRQQEVSEFSRQIKLLAKELEVPVVAMSQLN MAV_0079|M.avium_104 LRLVVVDYLQLMSSGKKVESRQLEVSEFSRQLKLLAKELEVPVVAISQLN MAB_4895c|M.abscessus_ATCC_199 LKLVVVDYLQLMTSGKKHESRQQEVSEFSRNLKLLAKELEVPVIAISQLN *:*:*:**:*** ***: **** ***:*** :**:***:::**:*:**** MSMEG_6892|M.smegmatis_MC2_155 RGPEQRTDKRPQVSDLRESGCMTANTRILRADTGAEVTFGELMATGERPL TH_2096|M.thermoresistible__bu RGPEQRTDKKPQVSDLRESGCLTANTRLLRADTGAEVTFGELMATGERPL MLBr_02680|M.leprae_Br4923 RSPEQRTDKKPMLSDLRESGSLEQDADVVILLHRPDAFDRDDPRGGEADL Mb0059|M.bovis_AF2122/97 RGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERPM Rv0058|M.tuberculosis_H37Rv RGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERPM MMAR_0076|M.marinum_M RGPEQRTDKKPMLSDLRESG------------------------------ MUL_0075|M.ulcerans_Agy99 RGPEQRTDKKPMLSDLRESG------------------------------ Mflv_0878|M.gilvum_PYR-GCK RGPEQRTDKKPMLSDLRESG------------------------------ Mvan_6030|M.vanbaalenii_PYR-1 RGPEQRTDKKPMLSDLRESG------------------------------ MAV_0079|M.avium_104 RGPEQRTDKKPMLSDLRESG------------------------------ MAB_4895c|M.abscessus_ATCC_199 RGPEQRTDKRPQVSDLRESG------------------------------ *.*******:* ::****** MSMEG_6892|M.smegmatis_MC2_155 VWSLDEHKRMVARPMTNVFPSGRKEVFTLRMASGREVEATANHPFLTLDG TH_2096|M.thermoresistible__bu VWSLDDRNRMVARPVSNVFYSGRKEVFKVRLASGRGXAVRADA------- MLBr_02680|M.leprae_Br4923 ILAKHRNGPTKTVTVAHQLHLSR---FTN-MAR----------------- Mb0059|M.bovis_AF2122/97 VWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFEG Rv0058|M.tuberculosis_H37Rv VWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFEG MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 WVPLGELKPGDRLATPRLVPEPVNTQRMHDSEVVMLAHMIGDGSCVKRQP TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 WTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQP Rv0058|M.tuberculosis_H37Rv WTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQP MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 IRYASIDEGNLLAVETAAEHFGVTPIRDEYAAAQVTTLRLPAPYRLTRGK TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 IRYEPVDEANLAAVTVSAAHSDGAAIRDDYLAARVPSL-RPARQRLPRGR Rv0058|M.tuberculosis_H37Rv IRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPSL-RPARQRLPRGR MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 RNPIAEWLDKLGLFGKRSYEKFVPAQVFALPNDQVALFLRHLWATDGSVR TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 CTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVR Rv0058|M.tuberculosis_H37Rv CTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVR MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 WDAKVGQGRVYYATTSRQLADDVVQLLLRVGVYARIKRAKKAGYRDCWHV TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 WDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRL Rv0058|M.tuberculosis_H37Rv WDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRL MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 LIYGRENQKRFVAHVGVHGARGAAARDLLAELESVTQDTNLDTVPKEVWS TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 HIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWA Rv0058|M.tuberculosis_H37Rv HIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWA MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 QVKAALIERGMSHRAFAKAMGTQFCGSALWKHAPSRSRLHRAASLLEDAA TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 QVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRA Rv0058|M.tuberculosis_H37Rv QVRNRLSAK--------QMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRA MMAR_0076|M.marinum_M -------------------------------------------------- MUL_0075|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0878|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6030|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_0079|M.avium_104 -------------------------------------------------- MAB_4895c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_6892|M.smegmatis_MC2_155 LHDLATNDVFWDEIVEITSIGEHDVYDGTVPGTHNFVAQGISAHNSLEQD TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 IHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQD Rv0058|M.tuberculosis_H37Rv IHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQD MMAR_0076|M.marinum_M ---------------------------------------------SLEQD MUL_0075|M.ulcerans_Agy99 ---------------------------------------------SLEQD Mflv_0878|M.gilvum_PYR-GCK ---------------------------------------------SIEQD Mvan_6030|M.vanbaalenii_PYR-1 ---------------------------------------------SIEQD MAV_0079|M.avium_104 ---------------------------------------------SLEQD MAB_4895c|M.abscessus_ATCC_199 ---------------------------------------------SLEQD MSMEG_6892|M.smegmatis_MC2_155 ADMVMLLHRPDAFDRDDPRGGEADIILGKHRNGPTANITVAHQLHFSRFT TH_2096|M.thermoresistible__bu -------------------------------------------------- MLBr_02680|M.leprae_Br4923 -------------------------------------------------- Mb0059|M.bovis_AF2122/97 ADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFA Rv0058|M.tuberculosis_H37Rv ADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFA MMAR_0076|M.marinum_M ADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFA MUL_0075|M.ulcerans_Agy99 ADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFA Mflv_0878|M.gilvum_PYR-GCK ADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTVTVAHQLHLSRFS Mvan_6030|M.vanbaalenii_PYR-1 ADMVILLHRPDAFESDDPRGGEADLIVAKHRAGPTRTITVAHQLHLSRFS MAV_0079|M.avium_104 ADMVILLNRPDAFERDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFA MAB_4895c|M.abscessus_ATCC_199 ADMVILLHRPDAFERDDPRGGEADLILGKHRNGPTATITVAHQLHLSRFT MSMEG_6892|M.smegmatis_MC2_155 NMAR TH_2096|M.thermoresistible__bu ---- MLBr_02680|M.leprae_Br4923 ---- Mb0059|M.bovis_AF2122/97 NMAR Rv0058|M.tuberculosis_H37Rv NMAR MMAR_0076|M.marinum_M NMAR MUL_0075|M.ulcerans_Agy99 NMAR Mflv_0878|M.gilvum_PYR-GCK NMAK Mvan_6030|M.vanbaalenii_PYR-1 NMAK MAV_0079|M.avium_104 NMAR MAB_4895c|M.abscessus_ATCC_199 NMAR