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LSTHSRLRIAGQMIVAVAALTAAVLAAPATAHAFSRPGLPVEYLDIPSPSMARDVRIQFQYGGPHAVFLL DGLRAQDDFNGWDINTAAFEWYDQSGISVIMPVGGQSSFYTDWYRPSRSNGQTYTYKWETFLTQELPQWL ASHRNISPTGHAAVGLSMAASSALTLAIWHPGQFVYAAVLSGALNPSEGWWPTLVGIAMNDAGRFDAESM WGPSSDPVWKRNDPTENLGKLVANNTRIWIYSGTGKASDFDSDATVGNLAAAQFLEKFLARTSRTFQEKY LAAGGRNGVFNFPSDGTHSWNYWGQQLRQMKPDLQRVLV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5880 | - | - | 100% (320) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | e-134 | 71.38% (311) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5560 | - | e-120 | 64.42% (312) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-123 | 66.13% (313) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_3335 | - | 1e-134 | 72.35% (311) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-123 | 66.13% (313) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-118 | 63.70% (303) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_1579 | - | 1e-102 | 56.01% (316) | antigen 85-B precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-119 | 64.22% (313) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-121 | 64.10% (312) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_3580 | - | 1e-132 | 69.35% (310) | antigen 85-C |
| M. thermoresistible (build 8) | TH_1495 | fbpA | 1e-117 | 60.58% (312) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-119 | 64.22% (313) | secreted antigen 85-C FbpC |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSKP
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSPVAGAFSKP
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATAGAFSRP
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAATAGAFSRP
Mflv_3335|M.gilvum_PYR-GCK MKWKEKAR---GTRKSLVRRVAAAALAAAALPGLIGVAGGSATAGAFSRP
MSMEG_3580|M.smegmatis_MC2_155 ----MRGI---AAWKALRR-FVIGALAALMLPGLIGFAGGSASAGAFSRP
Mvan_5880|M.vanbaalenii_PYR-1 ------------MLSTHSRLRIAGQMIVAVAALTAAVLAAPATAHAFSRP
TH_1495|M.thermoresistible__bu ----VANR---VAGRAVSDLMRAIGVLLLVLPVTVAVVNRAPVAAAYSRD
MAB_1579|M.abscessus_ATCC_1997 MEFLQKMR------GATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRP
: .. * *:*:
MLBr_02655|M.leprae_Br4923 GLPVEYLQVPSPSMGHDIKIQFQGGGQHAVYLLDGLRAQEDYNGWDINTP
MAV_5183|M.avium_104 GLPVEYLEVPSPSMGRNIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTP
Mb0134c|M.bovis_AF2122/97 GLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTP
Rv0129c|M.tuberculosis_H37Rv GLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTP
MMAR_0328|M.marinum_M GLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDINTP
MUL_4793|M.ulcerans_Agy99 GLPVEYLQIPSAAMGRDIKVQFQGGGAHSVYLLDGLRAQDDYNGWDINTP
Mflv_3335|M.gilvum_PYR-GCK GLPVEYLDVFSPSMNRDIRIQFQGGGPHAVYLLDGLRAQEDYNGWDINTP
MSMEG_3580|M.smegmatis_MC2_155 GLPVEYLDVFSPSMNRDIRVQFQGGGPHAVYLLDGLRAQDDYNGWDINTP
Mvan_5880|M.vanbaalenii_PYR-1 GLPVEYLDIPSPSMARDVRIQFQYGGPHAVFLLDGLRAQDDFNGWDINTA
TH_1495|M.thermoresistible__bu GLPVERLAVPSPSMGRDIIVQFQGGGPHSVYLLDGLRAQEDANGWDINTA
MAB_1579|M.abscessus_ATCC_1997 GLPVEYLQVPSPAMGRDIVVEFQPGGPHAVYLLDGQRAREDYNGWDIETT
***** * : *.:* ::: ::** ** *:*:**** **::* *****:*.
MLBr_02655|M.leprae_Br4923 AFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQEMP
MAV_5183|M.avium_104 AFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFLTQEMP
Mb0134c|M.bovis_AF2122/97 AFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMP
Rv0129c|M.tuberculosis_H37Rv AFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMP
MMAR_0328|M.marinum_M AFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTREMP
MUL_4793|M.ulcerans_Agy99 AFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTREMP
Mflv_3335|M.gilvum_PYR-GCK AFEWFYQSGLSTIMPVGGQSSFYSDWYQPSRGNGQNYTYKWETFLTQELP
MSMEG_3580|M.smegmatis_MC2_155 AFEWFYQSGLSTIMPVGGQSSFYTDWYQPSKGNGQDYTYKWETFLTQELP
Mvan_5880|M.vanbaalenii_PYR-1 AFEWYDQSGISVIMPVGGQSSFYTDWYRPSRSNGQTYTYKWETFLTQELP
TH_1495|M.thermoresistible__bu AFEWFHDSGISVVMPVGGESSFYTDWYQPARSRSGTVTYKWETFLTKELP
MAB_1579|M.abscessus_ATCC_1997 AFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTELP
*** : .**:*.:*****:** *::**.*: ... ********* *:*
MLBr_02655|M.leprae_Br4923 SWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFLNPS
MAV_5183|M.avium_104 LWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPS
Mb0134c|M.bovis_AF2122/97 AWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPS
Rv0129c|M.tuberculosis_H37Rv AWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPS
MMAR_0328|M.marinum_M AWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLNPS
MUL_4793|M.ulcerans_Agy99 AWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFLNPS
Mflv_3335|M.gilvum_PYR-GCK AWLEANRGVSRTGNAVVGLSMAGSASLTYAIHHPQQFIYAASLSGFLNPS
MSMEG_3580|M.smegmatis_MC2_155 AWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPEQFIYASTLSGFLNPS
Mvan_5880|M.vanbaalenii_PYR-1 QWLASHRNISPTGHAAVGLSMAASSALTLAIWHPGQFVYAAVLSGALNPS
TH_1495|M.thermoresistible__bu AWLAENRGQDPNGNAVVGLSMSGGAALNLATWYPQQFIFASSLSGYLSPS
MAB_1579|M.abscessus_ATCC_1997 QWLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQFVYAGALSAPLHPS
*: :: .:*.*****:. ::* * :* ** :*. **. * **
MLBr_02655|M.leprae_Br4923 EGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTR
MAV_5183|M.avium_104 EGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTR
Mb0134c|M.bovis_AF2122/97 EGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTR
Rv0129c|M.tuberculosis_H37Rv EGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTR
MMAR_0328|M.marinum_M EGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTR
MUL_4793|M.ulcerans_Agy99 EGWWPTLIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTR
Mflv_3335|M.gilvum_PYR-GCK EGWWPMLIGLAMNDAGGFNAESMWGPSSDPAWKRNDPMVNINQLVANNTR
MSMEG_3580|M.smegmatis_MC2_155 EGWWPMLIGLAMNDAGGYNAESMWGPSTDPAWKRNDPMVNINQLVANNTR
Mvan_5880|M.vanbaalenii_PYR-1 EGWWPTLVGIAMNDAGRFDAESMWGPSSDPVWKRNDPTENLGKLVANNTR
TH_1495|M.thermoresistible__bu QGLWPTLIGVAMQDAGGYNARDMWGPTSDIAWRRNDPTVNVARLAANNTA
MAB_1579|M.abscessus_ATCC_1997 DQKWQ--IRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANNTR
: * : :**.*:* ::* .**** :* .* **** :: :* ****
MLBr_02655|M.leprae_Br4923 IWVYCGNGAPNEL-----GGDNIPAKFLESLTLSTNEIFQNTYAASGGRN
MAV_5183|M.avium_104 IWVYCGNGTPSDL-----GGDNVPAKFLEGLTLRTNEQFQNNYAAAGGRN
Mb0134c|M.bovis_AF2122/97 IWVYCGNGTPSDL-----GGDNIPAKFLEGLTLRTNQTFRDTYAADGGRN
Rv0129c|M.tuberculosis_H37Rv IWVYCGNGTPSDL-----GGDNIPAKFLEGLTLRTNQTFRDTYAADGGRN
MMAR_0328|M.marinum_M IWVYCGNGTPSDL-----GGDNMPAKFLEGLTLRTNQTFRDTYLASGGRN
MUL_4793|M.ulcerans_Agy99 IWVYCGNGTPSDL-----GGDNMPAKFLEGLTLRTNQTFRDTYLASGGRN
Mflv_3335|M.gilvum_PYR-GCK IWIYCGTGTPSDLDSGTPGQNLMAAQFLEGFTLRTNVAFRDNYIAAGGNN
MSMEG_3580|M.smegmatis_MC2_155 LWVYCGTGTPSELDAGVSGGNLLAAQFLEGLTLRTNLTFRDQYIAAGGTN
Mvan_5880|M.vanbaalenii_PYR-1 IWIYSGTGKASDFDSDATVGNLAAAQFLEKFLARTSRTFQEKYLAAGGRN
TH_1495|M.thermoresistible__bu LWIYCGSGAMSDLDSGTDFGNNFSAQYLENITLSSNKEFQQKYVAAGGRN
MAB_1579|M.abscessus_ATCC_1997 LWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGAN
:*:*.*.* .:: : .. :* :. * : * : ** *
MLBr_02655|M.leprae_Br4923 GVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA------------
MAV_5183|M.avium_104 GVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQPAQPAQPA
Mb0134c|M.bovis_AF2122/97 GVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA-----
Rv0129c|M.tuberculosis_H37Rv GVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA-----
MMAR_0328|M.marinum_M GVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPAAPV
MUL_4793|M.ulcerans_Agy99 GVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEAPAAPV
Mflv_3335|M.gilvum_PYR-GCK GVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATA-------------
MSMEG_3580|M.smegmatis_MC2_155 AVFNFPPNGTHTWNYWGQQLLEMKPDIQRVLGAQSAT-------------
Mvan_5880|M.vanbaalenii_PYR-1 GVFNFPSDGTHSWNYWGQQLRQMKPDLQRVLV------------------
TH_1495|M.thermoresistible__bu AIFNFPANGTHSWAYWGSQLQEMKPQLLRVLGVTTAAPQTPAPAAPPIAG
MAB_1579|M.abscessus_ATCC_1997 AHFEFPKGGIHNWTYWGNQLRAMKADLVGYLTKPGTAAV-----------
. *:** .* *.* **..** ** :: *
MLBr_02655|M.leprae_Br4923 ----------
MAV_5183|M.avium_104 QPAQPAQPAT
Mb0134c|M.bovis_AF2122/97 ----------
Rv0129c|M.tuberculosis_H37Rv ----------
MMAR_0328|M.marinum_M APAA------
MUL_4793|M.ulcerans_Agy99 APAA------
Mflv_3335|M.gilvum_PYR-GCK ----------
MSMEG_3580|M.smegmatis_MC2_155 ----------
Mvan_5880|M.vanbaalenii_PYR-1 ----------
TH_1495|M.thermoresistible__bu AHPAGHP---
MAB_1579|M.abscessus_ATCC_1997 ----------