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MKLKEKWRGTARAAMRRVAAAALAAVALPGLIGFAGGSATAGAFSRPGLPVEYLDVFSPSMGRDIRVQFQ GGGPRAVYLLDGLRAQEDYNGWDINTPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSRGNGQNYTYKWET FLSQELPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPQQFIYAASLSGFLNPSEGWWPMLIGLAMN DAGGFNAESMWGPSSDPAWKRNDPMVNINQLVANNTRIWIYCGTGTPSDLDNGTPGNNLMAAQFLEGFTL RTNIAFRDNYIAAGGTNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | - | 100% (334) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5645 | - | e-135 | 69.16% (334) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5880 | - | e-134 | 71.38% (311) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0134c | fbpC | 1e-144 | 75.39% (321) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. gilvum PYR-GCK | Mflv_3335 | - | 0.0 | 93.99% (333) | putative esterase |
| M. tuberculosis H37Rv | Rv0129c | fbpC | 1e-144 | 75.39% (321) | secreted antigen 85-C FBPC (85C) (antigen 85 complex C) |
| M. leprae Br4923 | MLBr_02655 | fbpC2 | 1e-135 | 67.67% (331) | secreted antigen 85A, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-117 | 61.89% (328) | antigen 85-A precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-146 | 72.89% (332) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_5183 | - | 1e-143 | 73.37% (323) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_3580 | - | 1e-174 | 87.77% (319) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-141 | 71.73% (336) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-146 | 72.89% (332) | secreted antigen 85-C FbpC |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3061|M.vanbaalenii_PYR-1 MKLKEKWRG---TARAAMRRVAAAALAAVALPGLIGFAGGSA---TAGAF
Mflv_3335|M.gilvum_PYR-GCK MKWKEKARG---TRKSLVRRVAAAALAAAALPGLIGVAGGSA---TAGAF
MSMEG_3580|M.smegmatis_MC2_155 MRGIAAWK--------ALRRFVIGALAALMLPGLIGFAGGSA---SAGAF
MLBr_02655|M.leprae_Br4923 MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTA---IAVAF
MAV_5183|M.avium_104 MSFIEKVRKLRGAAATMPRRLAIAAVGASLLSGVAVAAGGSP---VAGAF
Mb0134c|M.bovis_AF2122/97 MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPA---TAGAF
Rv0129c|M.tuberculosis_H37Rv MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPA---TAGAF
MMAR_0328|M.marinum_M MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAA---TAGAF
MUL_4793|M.ulcerans_Agy99 MKFVEKLR---GAAAGAPRRLTIAAIGAALLSGLVGAVGGAA---TAGAF
TH_2078|M.thermoresistible__bu MKLVAKLRG---AARALPRRLTVAALAAALLPGLVGAFGGSA---TAGAF
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRG--ALARQSARRIAVAATAVAVLPGVAGIVGGTALTPVAGAF
* : *.. .. .. : *: *... * **
Mvan_3061|M.vanbaalenii_PYR-1 SRPGLPVEYLDVFSPSMGRDIRVQFQGGG--PRAVYLLDGLRAQEDYNGW
Mflv_3335|M.gilvum_PYR-GCK SRPGLPVEYLDVFSPSMNRDIRIQFQGGG--PHAVYLLDGLRAQEDYNGW
MSMEG_3580|M.smegmatis_MC2_155 SRPGLPVEYLDVFSPSMNRDIRVQFQGGG--PHAVYLLDGLRAQDDYNGW
MLBr_02655|M.leprae_Br4923 SKPGLPVEYLQVPSPSMGHDIKIQFQGGG--QHAVYLLDGLRAQEDYNGW
MAV_5183|M.avium_104 SKPGLPVEYLEVPSPSMGRNIKVQFQGGG--PHAVYLLDGLRAQDDYNGW
Mb0134c|M.bovis_AF2122/97 SRPGLPVEYLQVPSASMGRDIKVQFQGGG--PHAVYLLDGLRAQDDYNGW
Rv0129c|M.tuberculosis_H37Rv SRPGLPVEYLQVPSASMGRDIKVQFQGGG--PHAVYLLDGLRAQDDYNGW
MMAR_0328|M.marinum_M SRPGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGW
MUL_4793|M.ulcerans_Agy99 SRPGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGW
TH_2078|M.thermoresistible__bu SRPGLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGW
MAB_0176|M.abscessus_ATCC_1997 SRPGLPVEYLQVPSASMGREIKVQFQPGG--AKAVYLLDGLRARDDFSGW
*:******** : *.:*.::*::*** ** .*********::*:.**
Mvan_3061|M.vanbaalenii_PYR-1 DINTPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSRGNGQNYTYKWETFL
Mflv_3335|M.gilvum_PYR-GCK DINTPAFEWFYQSGLSTIMPVGGQSSFYSDWYQPSRGNGQNYTYKWETFL
MSMEG_3580|M.smegmatis_MC2_155 DINTPAFEWFYQSGLSTIMPVGGQSSFYTDWYQPSKGNGQDYTYKWETFL
MLBr_02655|M.leprae_Br4923 DINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFL
MAV_5183|M.avium_104 DINTPAFEEFYQSGLSVIMPVGGQSSFYSNWYQPSSGNGQNYTYKWETFL
Mb0134c|M.bovis_AF2122/97 DINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFL
Rv0129c|M.tuberculosis_H37Rv DINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFL
MMAR_0328|M.marinum_M DINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFL
MUL_4793|M.ulcerans_Agy99 DINTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFL
TH_2078|M.thermoresistible__bu DIETAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFL
MAB_0176|M.abscessus_ATCC_1997 DIETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYKWETFT
**:*.*** :*.**:* :**********::**.*: .:. *******
Mvan_3061|M.vanbaalenii_PYR-1 SQELPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPQQFIYAASLSG
Mflv_3335|M.gilvum_PYR-GCK TQELPAWLEANRGVSRTGNAVVGLSMAGSASLTYAIHHPQQFIYAASLSG
MSMEG_3580|M.smegmatis_MC2_155 TQELPAWLEANRGVSRTGNAVVGLSMAGSAALTYAIYHPEQFIYASTLSG
MLBr_02655|M.leprae_Br4923 TQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSG
MAV_5183|M.avium_104 TQEMPLWMQSNKQVSPAGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
Mb0134c|M.bovis_AF2122/97 TREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
Rv0129c|M.tuberculosis_H37Rv TREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSG
MMAR_0328|M.marinum_M TREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSG
MUL_4793|M.ulcerans_Agy99 TREMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSG
TH_2078|M.thermoresistible__bu TQELPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSG
MAB_0176|M.abscessus_ATCC_1997 TQELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSG
::*:* :: :* : **.*****...::* : ::*: * **.:***
Mvan_3061|M.vanbaalenii_PYR-1 FLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDP--AWKRNDPMVNINQ
Mflv_3335|M.gilvum_PYR-GCK FLNPSEGWWPMLIGLAMNDAGGFNAESMWGPSSDP--AWKRNDPMVNINQ
MSMEG_3580|M.smegmatis_MC2_155 FLNPSEGWWPMLIGLAMNDAGGYNAESMWGPSTDP--AWKRNDPMVNINQ
MLBr_02655|M.leprae_Br4923 FLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPR
MAV_5183|M.avium_104 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPR
Mb0134c|M.bovis_AF2122/97 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPMVQIPR
Rv0129c|M.tuberculosis_H37Rv FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDP--AWKRNDPMVQIPR
MMAR_0328|M.marinum_M FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPR
MUL_4793|M.ulcerans_Agy99 FLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPR
TH_2078|M.thermoresistible__bu FLNLSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDK
MAB_0176|M.abscessus_ATCC_1997 FLNPSD--MKFQIGLAMGDAGGFSASDMWGPDSDP--AWQRNDPFLNIQK
*** *: :****.*:**:....*** ** **:****:::* :
Mvan_3061|M.vanbaalenii_PYR-1 LVANNTRIWIYCGTGTPSDLDNGTPGNNLMAAQFLEGFTLRTNIAFRDNY
Mflv_3335|M.gilvum_PYR-GCK LVANNTRIWIYCGTGTPSDLDSGTPGQNLMAAQFLEGFTLRTNVAFRDNY
MSMEG_3580|M.smegmatis_MC2_155 LVANNTRLWVYCGTGTPSELDAGVSGGNLLAAQFLEGLTLRTNLTFRDQY
MLBr_02655|M.leprae_Br4923 LVANNTRIWVYCGNGAPNEL-----GGDNIPAKFLESLTLSTNEIFQNTY
MAV_5183|M.avium_104 LVANNTRIWVYCGNGTPSDL-----GGDNVPAKFLEGLTLRTNEQFQNNY
Mb0134c|M.bovis_AF2122/97 LVANNTRIWVYCGNGTPSDL-----GGDNIPAKFLEGLTLRTNQTFRDTY
Rv0129c|M.tuberculosis_H37Rv LVANNTRIWVYCGNGTPSDL-----GGDNIPAKFLEGLTLRTNQTFRDTY
MMAR_0328|M.marinum_M LVANNTRIWVYCGNGTPSDL-----GGDNMPAKFLEGLTLRTNQTFRDTY
MUL_4793|M.ulcerans_Agy99 LVANNTRIWVYCGNGTPSDL-----GGDNMPAKFLEGLTLRTNQTFRDTY
TH_2078|M.thermoresistible__bu LVANNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEY
MAB_0176|M.abscessus_ATCC_1997 IIDNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAY
:: *.**:*::** * . :: : . . ***.::: :* * : *
Mvan_3061|M.vanbaalenii_PYR-1 IAAGGTNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATV------
Mflv_3335|M.gilvum_PYR-GCK IAAGGNNGVFNFPTSGTHSWGYWGQQLQQMKPDIQRVLGAQATA------
MSMEG_3580|M.smegmatis_MC2_155 IAAGGTNAVFNFPPNGTHTWNYWGQQLLEMKPDIQRVLGAQSAT------
MLBr_02655|M.leprae_Br4923 AASGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA-----
MAV_5183|M.avium_104 AAAGGRNGVFNFPANGTHSWPYWNQQLMAMKPDMQQVLLSGNTTAAPAQP
Mb0134c|M.bovis_AF2122/97 AADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAP
Rv0129c|M.tuberculosis_H37Rv AADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAP
MMAR_0328|M.marinum_M LASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAP
MUL_4793|M.ulcerans_Agy99 LASGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAP
TH_2078|M.thermoresistible__bu IAAGGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVSAA-------
MAB_0176|M.abscessus_ATCC_1997 TAAGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH---------
* ** *. ::** * *.* **.:** ** *: *
Mvan_3061|M.vanbaalenii_PYR-1 -----------------
Mflv_3335|M.gilvum_PYR-GCK -----------------
MSMEG_3580|M.smegmatis_MC2_155 -----------------
MLBr_02655|M.leprae_Br4923 -----------------
MAV_5183|M.avium_104 AQPAQPAQPAQPAQPAT
Mb0134c|M.bovis_AF2122/97 AA---------------
Rv0129c|M.tuberculosis_H37Rv AA---------------
MMAR_0328|M.marinum_M EAPAAPVAPAA------
MUL_4793|M.ulcerans_Agy99 EAPAAPVAPAA------
TH_2078|M.thermoresistible__bu -----------------
MAB_0176|M.abscessus_ATCC_1997 -----------------