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VPVTRRRLVFIASRLCVLFAVAVSALMSPAAAAHAFSRPGLPVEYLMVPSTAMGRDIKVQFQSGGPGAPA VYLLDGLRARDDFNGWDIETNAFEMYHGSGLSVVMPVGGQSSFYTDWYRQACGNAGCSTYKWETFLTQEL PAYLAVERQVRPTGSAVVGLSMAGSAALTLAIHHPEQFRYAASLSGFLNLSEGWWPMLVGISMKDAGGYR SDDMWGPSSDPAWQRNDPMVNIGQLIANNTRVWVFAGNGKPADLGTGEPEGDNVPAKFLEGFTLRTNRTF QEQYLAGGGRNGVFNFPDSGTHSWGYWAEQLQSMKPDIQRVLGAAPGQSALSSPDN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5560 | - | - | 100% (336) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_5645 | - | e-140 | 72.62% (325) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_3061 | - | e-126 | 69.35% (310) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3834c | fbpA | 1e-127 | 68.71% (310) | secreted antigen 85-A FBPA (Mycolyl transferase 85A) |
| M. gilvum PYR-GCK | Mflv_1164 | - | 1e-138 | 70.95% (327) | putative esterase |
| M. tuberculosis H37Rv | Rv3804c | fbpA | 1e-127 | 68.71% (310) | secreted antigen 85-A FBPA (Mycolyl transferase 85A) |
| M. leprae Br4923 | MLBr_00097 | fbpA | 1e-125 | 65.22% (322) | antigen 85A, mycolytransferase |
| M. abscessus ATCC 19977 | MAB_0176 | - | 1e-102 | 57.91% (316) | antigen 85-A precursor |
| M. marinum M | MMAR_0328 | fbpC | 1e-123 | 63.64% (330) | secreted antigen 85-C FbpC |
| M. avium 104 | MAV_0214 | - | 1e-124 | 64.29% (322) | antigen 85-A |
| M. smegmatis MC2 155 | MSMEG_2078 | - | 1e-128 | 68.59% (312) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2078 | fbpA | 1e-139 | 76.85% (298) | SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) |
| M. ulcerans Agy99 | MUL_4793 | fbpC | 1e-123 | 63.64% (330) | secreted antigen 85-C FbpC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3834c|M.bovis_AF2122/97 MQLVDRVRGAVTGM-SRRLVVGAVGAALVSGLVGAVGG---TATAGAFSR
Rv3804c|M.tuberculosis_H37Rv MQLVDRVRGAVTGM-SRRLVVGAVGAALVSGLVGAVGG---TATAGAFSR
MLBr_00097|M.leprae_Br4923 MKFVDRFRGAVAGM-LRRLVVEAMGVALLSALIGVVG----SAPAEAFSR
MAV_0214|M.avium_104 MTLVDRLRGAVAGM-PRRLVVGAAGAALLSGLIGAVGG---SATAGAFSR
Mflv_1164|M.gilvum_PYR-GCK MKFVGKLRAAAR-----RSTVVALAAIVLPGLISAVGG---SATAGAFSR
TH_2078|M.thermoresistible__bu MKLVAKLRGAARAL-PRRLTVAALAAALLPGLVGAFGG---SATAGAFSR
Mvan_5560|M.vanbaalenii_PYR-1 MPVTRRRLVFIA------SRLCVLFAVAVSALMSP------AAAAHAFSR
MMAR_0328|M.marinum_M MKFVEKLRGAAAGA-PRRLTIAAIGAALLSGLVGAVGG---AATAGAFSR
MUL_4793|M.ulcerans_Agy99 MKFVEKLRGAAAGA-PRRLTIAAIGAALLSGLVGAVGG---AATAGAFSR
MSMEG_2078|M.smegmatis_MC2_155 MTFIDKIRGHWA----RRMTVAAVAALLLPGLVGVVGG---SATAGAFSR
MAB_0176|M.abscessus_ATCC_1997 MKLFSKMRGALARQSARRIAVAATAVAVLPGVAGIVGGTALTPVAGAFSR
* . : : . . :..: . :. * ****
Mb3834c|M.bovis_AF2122/97 PGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDI
Rv3804c|M.tuberculosis_H37Rv PGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDI
MLBr_00097|M.leprae_Br4923 PGLPVEYLQVPSPSMGRDIKVQFQNGGANSPALYLLDGLRAQDDFSGWDI
MAV_0214|M.avium_104 PGLPVEYLQVPSAAMGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDI
Mflv_1164|M.gilvum_PYR-GCK PGLPVEYLMVPSAGMGRDIKVQFQSGGPNAPGVYLLDGLRAQDDFNGWDI
TH_2078|M.thermoresistible__bu PGLPVEYLMVPSAAMGRDIKVQFQSGGEGSPGVYLLDGLRARDDFNGWDI
Mvan_5560|M.vanbaalenii_PYR-1 PGLPVEYLMVPSTAMGRDIKVQFQSGGPGAPAVYLLDGLRARDDFNGWDI
MMAR_0328|M.marinum_M PGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDI
MUL_4793|M.ulcerans_Agy99 PGLPVEYLQIPSAAMGRDIKVQFQGGG--AHSVYLLDGLRAQDDYNGWDI
MSMEG_2078|M.smegmatis_MC2_155 PGLPVEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQDDFNGWDI
MAB_0176|M.abscessus_ATCC_1997 PGLPVEYLQVPSASMGREIKVQFQPGG--AKAVYLLDGLRARDDFSGWDI
******** :**..***:****** ** : .:*****:**:**:.****
Mb3834c|M.bovis_AF2122/97 NTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACGKAGCQTYKWETFLTS
Rv3804c|M.tuberculosis_H37Rv NTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACGKAGCQTYKWETFLTS
MLBr_00097|M.leprae_Br4923 NTTAFEWYYQSGISVVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTS
MAV_0214|M.avium_104 NTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTS
Mflv_1164|M.gilvum_PYR-GCK NTPAFEWYLDSGLAVVMPVGGQSSFYSDWYSPACGKAGCSTYKWETFLTQ
TH_2078|M.thermoresistible__bu ETAAFEWYYESGLSVIMPVGGQSSFYSDWYSPACGNNGCQTYKWETFLTQ
Mvan_5560|M.vanbaalenii_PYR-1 ETNAFEMYHGSGLSVVMPVGGQSSFYTDWYRQACGNAGCSTYKWETFLTQ
MMAR_0328|M.marinum_M NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
MUL_4793|M.ulcerans_Agy99 NTPAFEEYYNSGLSVVMPVGGQSSFYSDWYQPSQGNGQGYTYKWETFLTR
MSMEG_2078|M.smegmatis_MC2_155 NTNAFEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYKWETFLTS
MAB_0176|M.abscessus_ATCC_1997 ETTAFEDYYQSGISMVMPVGGQSSFYTDWYNPAKGKDGVWTYKWETFTTQ
:* *** : **::: **********:*** : *: ******* *
Mb3834c|M.bovis_AF2122/97 ELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSGLL
Rv3804c|M.tuberculosis_H37Rv ELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSGLL
MLBr_00097|M.leprae_Br4923 ELPQYLQSNKQIKPTGSAAVGLSMAGLSALTLAIYHPDQFIYVGSMSGLL
MAV_0214|M.avium_104 ELPQYLSAQKQVKPTGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALL
Mflv_1164|M.gilvum_PYR-GCK ELPAYLAANKGVDPNRNAAIGLSMAGSAALTLAIYYPQQFQYAGSMSGFL
TH_2078|M.thermoresistible__bu ELPAYLASNYGVDRNRNAAVGLSMAGSAALVLAIYYPQQFQYAASLSGFL
Mvan_5560|M.vanbaalenii_PYR-1 ELPAYLAVERQVRPTGSAVVGLSMAGSAALTLAIHHPEQFRYAASLSGFL
MMAR_0328|M.marinum_M EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
MUL_4793|M.ulcerans_Agy99 EMPAWLQANKGVSPTGNAAVGLSMSGGSALVLAAYYPQQFPYAASLSGFL
MSMEG_2078|M.smegmatis_MC2_155 ELPEWLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYAGSMSGFL
MAB_0176|M.abscessus_ATCC_1997 ELPAYLAANKGISQTGNAVVGLSMGASAALTLSIYHPQLFVYAGALSGFL
*:* :* : : . ...:****.. :** *: ::*: * *..::*.:*
Mb3834c|M.bovis_AF2122/97 DPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDP--AWQRNDPLLNVGKLI
Rv3804c|M.tuberculosis_H37Rv DPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDP--AWQRNDPLLNVGKLI
MLBr_00097|M.leprae_Br4923 DPSNAMGPSLIGLAMGDAGGYKAADMWGPSTDP--AWKRNDPTVNVGTLI
MAV_0214|M.avium_104 DPSQGMGPSLIGLAMGDAGGYKAADMWGPKEDP--AWARNDPSLQVGKLV
Mflv_1164|M.gilvum_PYR-GCK NLSEGWWPALVNISMGDAGGYDANDMWGRTEDPNSAWKRNDPMVNIGKLV
TH_2078|M.thermoresistible__bu NLSEGWWPMLVGLAMGDAGGYDPNDMWGRTEDPNSAWKRNDPMVNIDKLV
Mvan_5560|M.vanbaalenii_PYR-1 NLSEGWWPMLVGISMKDAGGYRSDDMWGPSSDP--AWQRNDPMVNIGQLI
MMAR_0328|M.marinum_M NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
MUL_4793|M.ulcerans_Agy99 NPSEGWWPTLIGLAMNDSGGYNANSMWGPSTDP--AWKRNDPMVQIPRLV
MSMEG_2078|M.smegmatis_MC2_155 NPSEGWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPMVQIPRLV
MAB_0176|M.abscessus_ATCC_1997 NPSD--MKFQIGLAMGDAGGFSASDMWGPDSDP--AWQRNDPFLNIQKII
: *: :.::* *:**: . .*** ** ** **** ::: ::
Mb3834c|M.bovis_AF2122/97 ANNTRVWVYCGNGKPSDLG-----GNNLPAKFLEGFVRTSNIKFQDAYNA
Rv3804c|M.tuberculosis_H37Rv ANNTRVWVYCGNGKPSDLG-----GNNLPAKFLEGFVRTSNIKFQDAYNA
MLBr_00097|M.leprae_Br4923 ANNTRIWMYCGNGKPTELG-----GNNLPAKLLEGLVRTSNIKFQDGYNA
MAV_0214|M.avium_104 ANNTRIWVYCGNGKPSDLG-----GDNLPAKFLEGFVRTSNLKFQDAYNG
Mflv_1164|M.gilvum_PYR-GCK ANNTRIWVYCGDGKPAEVNGNVA-GNNLPAKFLEGLTIRTNRTFQEEYIA
TH_2078|M.thermoresistible__bu ANNTRIWVFCGDGTPADIGAGVPEGDNFNAKFLESFTLRTNKTFQQEYIA
Mvan_5560|M.vanbaalenii_PYR-1 ANNTRVWVFAGNGKPADLGTGEPEGDNVPAKFLEGFTLRTNRTFQEQYLA
MMAR_0328|M.marinum_M ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
MUL_4793|M.ulcerans_Agy99 ANNTRIWVYCGNGTPSDLG-----GDNMPAKFLEGLTLRTNQTFRDTYLA
MSMEG_2078|M.smegmatis_MC2_155 ANNTRIWVYCGNGQPNELG-----GGDLPATFLEGLTIRTNETFRDNYIA
MAB_0176|M.abscessus_ATCC_1997 DNGTRLWIYCGTGDSTDLDATRNGFENFTGGFLEGMAIGSNKKFVEAYTA
*.**:*::.* * . ::. :. . :**.:. :* .* : * .
Mb3834c|M.bovis_AF2122/97 GGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPNTGPAPQGA-
Rv3804c|M.tuberculosis_H37Rv GGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPNTGPAPQGA-
MLBr_00097|M.leprae_Br4923 GGGHNAVFNFPDSGTHSWEYWGEQLNDMKPDLQQYLGATP-------GA-
MAV_0214|M.avium_104 AGGHNAVWNFDANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAAT
Mflv_1164|M.gilvum_PYR-GCK AGGKNGVFNFPANGTHDWPYWGQQLQQMKPDIQRVLGAVPQPSAPAAPVA
TH_2078|M.thermoresistible__bu AGGKNGVFNFPDAGTHSWGYWGQQLQQMKPDIQRVLGVS------AA---
Mvan_5560|M.vanbaalenii_PYR-1 GGGRNGVFNFPDSGTHSWGYWAEQLQSMKPDIQRVLGAAPGQSALSSPDN
MMAR_0328|M.marinum_M SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEA
MUL_4793|M.ulcerans_Agy99 SGGRNGVFNFPTNGTHSWPYWNQQLVAMKGDILKVLNGPAVPAAPAAPEA
MSMEG_2078|M.smegmatis_MC2_155 AGGNNGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG-------------
MAB_0176|M.abscessus_ATCC_1997 AGGKNAHIEFPPGGIHNWTYWGQQLRAMKPDMVAYLQSH-----------
.**.*. :* * *.* ** :* * *: *
Mb3834c|M.bovis_AF2122/97 ---------
Rv3804c|M.tuberculosis_H37Rv ---------
MLBr_00097|M.leprae_Br4923 ---------
MAV_0214|M.avium_104 NAGNGQGT-
Mflv_1164|M.gilvum_PYR-GCK AEAPGAGG-
TH_2078|M.thermoresistible__bu ---------
Mvan_5560|M.vanbaalenii_PYR-1 ---------
MMAR_0328|M.marinum_M PAAPVAPAA
MUL_4793|M.ulcerans_Agy99 PAAPVAPAA
MSMEG_2078|M.smegmatis_MC2_155 ---------
MAB_0176|M.abscessus_ATCC_1997 ---------