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TITEQPTDSTALPTGEDIDAAIARGQRAYELDRKHVFHSWSAQAQINPMTVLAAQGSYVWDGEGNKLLDF SSQLVNTNIGHQHPKVVAAIAEQAATLCTIAPQHVNDARSEAARLVAERTPGDLNRVFFTNGGADAVEHA VRMARLHTGRYKVLSRYRSYHGGTETAINLTGDPRRWPNDHGNAGIVHFNGPFLYRSAFHAETEEQETQR ALEHLDRLVQMEGPSTIAAIILESVPGTAGIMVPPPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFA IENFDVVPDLITFAKGITSGYVPLGGVAINDAIYSTFADRAYPGGLTYSGHPLATACAVATINAMEDEGM VANAARIGERVLGPGLRELAARHRSVGEVRGLGVFWAIELVANRETREPLAPYGGSSPAMAAVLAACKSG GLLPFANFNRIHAVPPCNVTDDEVAEGLRILDAALSVADEYVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1823 | - | - | 100% (464) | hypothetical protein Mvan_1823 |
| M. vanbaalenii PYR-1 | Mvan_5776 | - | 0.0 | 78.35% (448) | hypothetical protein Mvan_5776 |
| M. vanbaalenii PYR-1 | Mvan_1570 | - | 3e-58 | 34.79% (388) | hypothetical protein Mvan_1570 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3362 | - | 3e-56 | 35.33% (368) | hypothetical protein Mb3362 |
| M. gilvum PYR-GCK | Mflv_0358 | - | 0.0 | 92.46% (464) | hypothetical protein Mflv_0358 |
| M. tuberculosis H37Rv | Rv3329 | - | 6e-56 | 35.33% (368) | hypothetical protein Rv3329 |
| M. leprae Br4923 | MLBr_00485 | gabT | 6e-48 | 32.23% (422) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4345c | - | 0.0 | 74.57% (464) | hypothetical protein MAB_4345c |
| M. marinum M | MMAR_3558 | - | 4e-60 | 36.01% (386) | aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) |
| M. avium 104 | MAV_4304 | - | 1e-58 | 36.41% (368) | hypothetical protein MAV_4304 |
| M. smegmatis MC2 155 | MSMEG_2450 | - | 0.0 | 81.58% (456) | hypothetical protein MSMEG_2450 |
| M. thermoresistible (build 8) | TH_1978 | - | 1e-61 | 36.13% (393) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_2791 | - | 4e-60 | 36.01% (386) | hypothetical protein MUL_2791 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3362|M.bovis_AF2122/97 ------------------------------------------MHFARHGA
Rv3329|M.tuberculosis_H37Rv ------------------------------------------MHFARHGA
MAV_4304|M.avium_104 ------------------------------------MTDHLWLHFARHGP
MMAR_3558|M.marinum_M -----------------------------MTELSAKANRHLWGHFARHGA
MUL_2791|M.ulcerans_Agy99 -----------------------------MTELSAKANRHLWGHFARHGA
TH_1978|M.thermoresistible__bu ----------------------------MSTDRAAQADRHLWGHFARHGP
Mvan_1823|M.vanbaalenii_PYR-1 -----MTITEQPTDSTALPTGEDIDAAIARGQRAYELDRKHVFHSWSAQA
Mflv_0358|M.gilvum_PYR-GCK -----MTITDQPTDTAGLPTGEDLDSAIARGRRAYDLDRRHVFHSWSAQA
MSMEG_2450|M.smegmatis_MC2_155 -----MTAIQEST---LLPNGLTVDTAKAEAARAYELDRAHVFHSWSAQE
MAB_4345c|M.abscessus_ATCC_199 MKDETMTLTQETET---LPNGLSAADAFQEASRAYTLDRAHVFHSWSAQS
MLBr_00485|M.leprae_Br4923 ---------------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVG
Mb3362|M.bovis_AF2122/97 GIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQA
Rv3329|M.tuberculosis_H37Rv GIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQA
MAV_4304|M.avium_104 GITPPIITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQA
MMAR_3558|M.marinum_M GITPPIITRGEGVTIWDDRGNSYLDGLSGLFVVQAGHGRTELAEAAAKQA
MUL_2791|M.ulcerans_Agy99 GITPPIITRGEGVTIWDDRGNSYLDGLSGLFVVQAGHGRTELAEAAAKQA
TH_1978|M.thermoresistible__bu GVTPPIIVRGDGVTIWDDHGRRYLDGLSGLFVVQAGHGRAELAEAAARQA
Mvan_1823|M.vanbaalenii_PYR-1 QINPMTVLAAQGSYVWDGEGNKLLDFSSQLVNTNIGHQHPKVVAAIAEQA
Mflv_0358|M.gilvum_PYR-GCK QITPMTVLAAQGSYVWDGDGTRLLDFSSQLVNTNIGHQHPKVVAAIAEQA
MSMEG_2450|M.smegmatis_MC2_155 EISPMTVTAAQGSYLWDGDGNRLLDFSSQLVNTNIGHQHPKVVAAIAEQA
MAB_4345c|M.abscessus_ATCC_199 QIKPMTIVASAGSYVWDGGGRRLLDFSSQLVNTNIGHQHPKVVAAIQRQA
MLBr_00485|M.leprae_Br4923 VTLPVFVTRAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQV
: . * : * * :* * : . * ..:. * *.
Mb3362|M.bovis_AF2122/97 GTLGYFPLWGYATPPAIELAERLARYAPG-DLNRVFFTSGGTEAVETAWK
Rv3329|M.tuberculosis_H37Rv GTLGYFPLWGYATPPAIELAERLARYAPG-DLNRVFFTSGGTEAVETAWK
MAV_4304|M.avium_104 GTLAFFPLWGYATPPAIELAERLAGYAPG-DLNRVFFTTGGTEAVETAWK
MMAR_3558|M.marinum_M ETLAFFPLWSYATPTAIELAERVAHYAPG-DLNRVFFTTGGGEAVESAWK
MUL_2791|M.ulcerans_Agy99 ETLAFFPLWSYATPTAIELAERVAHYAPG-DLNRVFFTTGGGEAVESAWK
TH_1978|M.thermoresistible__bu GQLAYFPLWSYATPPAIELAERIAHYAPG-DLNRVFFTTGGGEAVESAWK
Mvan_1823|M.vanbaalenii_PYR-1 ATLCTIAPQ-HVNDARSEAARLVAERTPG-DLNRVFFTNGGADAVEHAVR
Mflv_0358|M.gilvum_PYR-GCK ATLCTIAPQ-HVNDVRSEAARLIAERTPG-DLNRIFFTNGGADAVEHAVR
MSMEG_2450|M.smegmatis_MC2_155 AKLCTVAPQ-HANAARSEAARLIAERTPG-ELNKIFFTNGGADAVEHAVR
MAB_4345c|M.abscessus_ATCC_199 AKLCTVAPQ-YANDARSEAARLIAERTPG-DLDKIFFTNGGADANEHAVR
MLBr_00485|M.leprae_Br4923 ADFTHTCFIITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIK
: :. : :** .: .: ..* :* * : :
Mb3362|M.bovis_AF2122/97 VAKQYFKLTGKPGKHKVISRSIAYHGTTQGALAITGLPLF-KAPFEPLTP
Rv3329|M.tuberculosis_H37Rv VAKQYFKLTGKPGKQKVISRSIAYHGTTQGALAITGLPLF-KAPFEPLTP
MAV_4304|M.avium_104 LAKQYFKLTGKPGKHKVISRAVAYHGTTQGALAITGLPRY-KAPFEPVTP
MMAR_3558|M.marinum_M LAKQYFKETGKPGKYKAISRSTAYHGTPHGALAITGLPAF-KAPFEPLTP
MUL_2791|M.ulcerans_Agy99 LAKQYFKETGKPGKYKAISRSTAYHGTPHGALAITGLPAF-KAPFEPLTP
TH_1978|M.thermoresistible__bu LAKQYFKLTGKPGKHKVVSRAVAYHGTPQGALAITGLPMF-KAPFEPLTP
Mvan_1823|M.vanbaalenii_PYR-1 MARLHT------GRYKVLSRYRSYHGGTETAINLTGDPR--RWPNDHGNA
Mflv_0358|M.gilvum_PYR-GCK MARLHT------GRYKVLSRYRSYHGGTETAINLTGDPR--RWPNDHGNA
MSMEG_2450|M.smegmatis_MC2_155 MARLHT------GRYKVLSRYRAYHGGTDTAINLTGDPR--RWPNDRGNS
MAB_4345c|M.abscessus_ATCC_199 MARLHT------GRYKVLARYRSYHGGTDTAINLTGDPR--RWPNDYGNS
MLBr_00485|M.leprae_Br4923 VARSYTR------KPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAP
:*: : : .:: :*** .. :: :*. . : .
Mb3362|M.bovis_AF2122/97 GGFRVPNTNFYRAP--LHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLE
Rv3329|M.tuberculosis_H37Rv GGFRVPNTNFYRAP--LHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLE
MAV_4304|M.avium_104 GGFRVPNTNFYRAPEAFANDPKGFGLWAADRIAEAIEFEGPDTVAAVFVE
MMAR_3558|M.marinum_M GGVRIPNTNFYRAPAPYADDSKEFGLWAANRIAEAIEFEGPDTVAAVFLE
MUL_2791|M.ulcerans_Agy99 GGVRIPNTNFYRAPAPYADDSKDFGLWAANRIAEAIEFEGPDTVAAVFLE
TH_1978|M.thermoresistible__bu GGFRVPNTNFYRAPAPYRDDEKAFGRYCADRIAETIEFEGPDTVAAVVLE
Mvan_1823|M.vanbaalenii_PYR-1 GIVHFNGPFLYRSAFHAETEEQET-QRALEHLDRLVQMEGPSTIAAIILE
Mflv_0358|M.gilvum_PYR-GCK GIVHFDGPFLYRSTFHADTEEQET-QRALEHLDRLIRMEGPSTIAAIILE
MSMEG_2450|M.smegmatis_MC2_155 GIVHFNGPFLYRSSFYAETEEQES-QRALEYLEKLIQMEGPSTIAAIILE
MAB_4345c|M.abscessus_ATCC_199 GVVHFHGPFLYRSVFNSANEEQET-ERALAHLEQTIRLEGPSTIAAIVLE
MLBr_00485|M.leprae_Br4923 EIYRAPLSYPYRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIE
: . ** : . *.. :**:.:*
Mb3362|M.bovis_AF2122/97 PVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACED
Rv3329|M.tuberculosis_H37Rv PVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACED
MAV_4304|M.avium_104 PVQNAGGSIPPPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACAD
MMAR_3558|M.marinum_M PVQNAGGCFPPPPGYFERVREICDEYDVLLVSDEVICAFGRIGSMFACND
MUL_2791|M.ulcerans_Agy99 PVQNAGGCFPPPPGYFERVREICDEYDVLLVSDEVICAFGRIGSMFACND
TH_1978|M.thermoresistible__bu PVQNAGGCIPPPPGYFERVREICDTYDVLLISDEVICAFGRIGSMFACDD
Mvan_1823|M.vanbaalenii_PYR-1 SVPGTAGIMVPPPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIEN
Mflv_0358|M.gilvum_PYR-GCK SVPGTAGIMVPPPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIDN
MSMEG_2450|M.smegmatis_MC2_155 SIPGTAGIMVPPPGYLAGVRELCTRYGIVFIADEVMAGFGRSGKWFSINH
MAB_4345c|M.abscessus_ATCC_199 SIPGTAGVMVPPPGYMAGVRELCDQFGIVFIADEVMAGFGRTGEWFAINH
MLBr_00485|M.leprae_Br4923 PIQGEGGFIVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEH
.: . .* : .. *:: : : * .:::::*** .*.* * *: .
Mb3362|M.bovis_AF2122/97 LGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGH
Rv3329|M.tuberculosis_H37Rv LGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGH
MAV_4304|M.avium_104 FGYVPDMITCAKGMTSGYSPIGAMIASERLFEPFADGDTMFPHGYTFGGH
MMAR_3558|M.marinum_M FGYVPDIITCAKGMTSGYSPIGAMVASDRLFEPFNDGKTTFAHGYTFGGH
MUL_2791|M.ulcerans_Agy99 FGYVPDIITCAKGMTSGYSPIGAMVASDRLFEPFNDGKTTFAHGYTFGGH
TH_1978|M.thermoresistible__bu FGYQPDIITCAKGLTSGYAPLGAMIATDRLFEPFADGKTVFPHGYTFGGH
Mvan_1823|M.vanbaalenii_PYR-1 FDVVPDLITFAKGITSGYVPLGGVAINDAIYSTFADR--AYPGGLTYSGH
Mflv_0358|M.gilvum_PYR-GCK FGVVPDLITFAKGVTSGYVPLGGVAINDAIYSTFADR--AYPGGLTYSGH
MSMEG_2450|M.smegmatis_MC2_155 FDVVPDLMTFAKGVNSGYVPLGGVAISPEIYETFAHR--AYPGGLTYSGH
MAB_4345c|M.abscessus_ATCC_199 FNVVPDLLTFAKGVNSGYVPLGGVAINGAIAETFSER--AYPGGLTYSGH
MLBr_00485|M.leprae_Br4923 DGIVPDLICTAKGIADGLPLAAVTGRAEIMNAPHVSG-----LGGTFGGN
. **:: ***: .* . : .. * *:.*:
Mb3362|M.bovis_AF2122/97 PVSAAVGLANLDIFEREGLSDHVKRN-SPALRATLEKLYDLP-IVGDIRG
Rv3329|M.tuberculosis_H37Rv PVSAAVGLANLDIFEREGLSDHVKRN-SPALRATLEKLYDLP-IVGDIRG
MAV_4304|M.avium_104 PVSAAVGLVNLDIFEREGLNDRVRTL-APTFRATLEKLYDLP-IVGDVRG
MMAR_3558|M.marinum_M PVSSAVALANLDIFEREGLNDHVKQN-APAFRTTLEKLLDLP-IVGDVRG
MUL_2791|M.ulcerans_Agy99 PVSSAVALANLDIFEREGLNDHVKQN-APAFRTTLEKLLDLP-IVGDVRG
TH_1978|M.thermoresistible__bu PVSAAVALANLDIFEREGLNDRVRTL-SPLLRATLERLYELP-IVGDVRG
Mvan_1823|M.vanbaalenii_PYR-1 PLATACAVATINAMEDEGMVANAARIGERVLGPGLRELAARHRSVGEVRG
Mflv_0358|M.gilvum_PYR-GCK PLACACAVATITAMEDEGMVANAARIGREVLGPGLRELAARHRSVGEVRG
MSMEG_2450|M.smegmatis_MC2_155 PLACAAAVATINAMEDEGMVENAAKVGAEVIGPGLAELAAKHRSVGEVRG
MAB_4345c|M.abscessus_ATCC_199 PLATAAAVATIEAMDEEGMIGNARRIGRDVLGPQLQRLKERHRSIGEIRG
MLBr_00485|M.leprae_Br4923 PVACAAALATITTIENDGLIQRAQQI-ERLITDRLLRLQDADDRIGDVRG
*:: * .:..: :: :*: .. : * .* :*::**
Mb3362|M.bovis_AF2122/97 EGYFFGIELVKDQATKQTFTDDERARLL-GQVSAALFEAGLYCRTDDRGD
Rv3329|M.tuberculosis_H37Rv EGYFFGIELVKDQATKQTFTDDERARLL-GQVSAALFEAGLYCRTDDRGD
MAV_4304|M.avium_104 EGFFYGVELVKDRATKQTFTDSERRALL-GRVGAALFEAGLYCRTDDRGD
MMAR_3558|M.marinum_M EGFFYGIELVKDKDTKATFSDEESERLLRGFLSSALLEAGLYCRADDRGD
MUL_2791|M.ulcerans_Agy99 EGFFYGIELVKDKDTKATFSDEESERLLRGFLSSALLEAGLYCRADDRGD
TH_1978|M.thermoresistible__bu EGYFFAVELVQDKAGRQPFSAEESARLV-AHLNRALLDAGLYCRADNRGD
Mvan_1823|M.vanbaalenii_PYR-1 LGVFWAIELVANRETREPLAPYGGSSPAMAAVLAACKSGGLLPFANFN--
Mflv_0358|M.gilvum_PYR-GCK LGVFWAVELVANQQTREPLAPYGGSSPAMNAVVAACKSGGLLPFANFN--
MSMEG_2450|M.smegmatis_MC2_155 LGVFWAVELVKDQKTREPLAPYGSSSPAMNAVIAACKSGGLLPFANFN--
MAB_4345c|M.abscessus_ATCC_199 LGVFWAIELVANPESREPLSPYGTSNAAINSVVAECKATGLLPFANFN--
MLBr_00485|M.leprae_Br4923 RGAMIAVELVKSGTAEPDPELTEKVATAAHATGVIILTCGMFGN------
* : .:*** . . *:
Mb3362|M.bovis_AF2122/97 PVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL
Rv3329|M.tuberculosis_H37Rv PVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL
MAV_4304|M.avium_104 SVIQLAPPLISGQAEFDTIEAALRGVLSDECRRL---
MMAR_3558|M.marinum_M PVVQLAPPLISGQQEFDKMEQILRGVLSEAWSRL---
MUL_2791|M.ulcerans_Agy99 PVVQLAPPLISGQQEFDKMEQILRGVLSEAWSRL---
TH_1978|M.thermoresistible__bu TVVQVAPPLISGPAEFDAMHDILRTVLKDAPNHV---
Mvan_1823|M.vanbaalenii_PYR-1 -RIHAVPPCNVTDDEVAEGLRILDAALSVADEYVV--
Mflv_0358|M.gilvum_PYR-GCK -RIHAVPPCNVTDDEVAEGLRILDAALSVADDYTV--
MSMEG_2450|M.smegmatis_MC2_155 -RIHVVPPCNVSADEAREGLAILDSALDVADEHTV--
MAB_4345c|M.abscessus_ATCC_199 -RIHAVPPCSVTDLEVQEGIKSLDTALAIADEYVVP-
MLBr_00485|M.leprae_Br4923 -IIRLLPPLTISDELLAEGLDILSRILGDF-------
:: ** * *