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CCPCRVIGHGVTVLLAFLAAVFLAVGIVVRQRATLDVPAEHGVSPVMIQTLVRRPLWWAGTASAVAGFVF QALALANGSLLLVQPILVSALLFALPLSARLAHRRVTRAEWAWAVLLTLALAVFVVLAKASPGDYEASLS TSAVVAVVCTVAVLACVIVATRIAGWIRAVLLAVAVGVLFGVVAVLTKLVMHVLTNEGFVAVLTTPVLYL LALLGVVATLLQQSAFHAGSLQTSVPTMLVLEPMIAVILGAVVLGEHLNAGRWDAVALVVSTVAMVAGTI ALGRDEGAYEEQLEADLAQKAQAASGNG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5745 | - | - | 100% (309) | hypothetical protein Mvan_5745 |
| M. vanbaalenii PYR-1 | Mvan_2432 | - | 5e-58 | 46.83% (284) | hypothetical protein Mvan_2432 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2748c | - | 5e-54 | 44.18% (292) | hypothetical protein Mb2748c |
| M. gilvum PYR-GCK | Mflv_1077 | - | 1e-132 | 85.21% (284) | hypothetical protein Mflv_1077 |
| M. tuberculosis H37Rv | Rv2729c | - | 2e-54 | 44.18% (292) | hypothetical protein Rv2729c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2553 | - | 3e-12 | 24.55% (277) | putative integral membrane protein |
| M. marinum M | MMAR_1983 | - | 3e-48 | 39.57% (278) | hypothetical protein MMAR_1983 |
| M. avium 104 | MAV_1660 | - | 2e-52 | 43.34% (293) | hypothetical protein MAV_1660 |
| M. smegmatis MC2 155 | MSMEG_6539 | - | 1e-110 | 68.81% (295) | hypothetical protein MSMEG_6539 |
| M. thermoresistible (build 8) | TH_3271 | - | 1e-106 | 66.89% (299) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3372 | - | 3e-46 | 39.02% (287) | hypothetical protein MUL_3372 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2748c|M.bovis_AF2122/97 ------MASVEF-ATILALG--AALLAGIGYVTLQRSARQVTAEEYVGHL
Rv2729c|M.tuberculosis_H37Rv ------MASVEF-ATILALG--AALLAGIGYVTLQRSARQVTAEEYVGHF
MMAR_1983|M.marinum_M ------MANVEV-SASLALG--AALLAGVGYVVLQRSAQQVTEDE-VGHF
MUL_3372|M.ulcerans_Agy99 ------MTTTEI-AAVLALG--AAFASALGNVTRQRSAQEITDEQ-VGHL
MAV_1660|M.avium_104 ------MPRTEIIAALLALS--SALCVATGDVLQQRAAHCITDRE-LGPV
Mvan_5745|M.vanbaalenii_PYR-1 MCCPCRVIGHGV-TVLLAFL--AAVFLAVGIVVRQRATLDVPAEHGVSPV
Mflv_1077|M.gilvum_PYR-GCK ----------------------------MGIVVRQRATLDVPAEDGISAV
MSMEG_6539|M.smegmatis_MC2_155 ------MLGNSI-AVLLALC--AAIFMAVGIVVRQRATLDVPAGKGVSTV
TH_3271|M.thermoresistible__bu ------VLGQGL-AVLLAVC--AAVFAAVGIVVRQRATMDVPPEKGVSTV
MAB_2553|M.abscessus_ATCC_1997 -------MLIGIAAAMLACFGYGTASVLQGYGARQSSTEVGVAADHGPSL
* * :: . .
Mb2748c|M.bovis_AF2122/97 TLFHLSLRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFAL
Rv2729c|M.tuberculosis_H37Rv TLFHLSLRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFAL
MMAR_1983|M.marinum_M TLLHLSLRHGQWWLGSAAALSSFTLQAIALTMGSVVLVQSLQATALLFAL
MUL_3372|M.ulcerans_Agy99 ELFWLSLRDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFAL
MAV_1660|M.avium_104 ELFAGLLRSQRWWWGAVLLLASIGLQAAALGGGSVLLVQALLMFSVLFAL
Mvan_5745|M.vanbaalenii_PYR-1 MIQTLVRR-PLWWAGTASAVAGFVFQALALANGSLLLVQPILVSALLFAL
Mflv_1077|M.gilvum_PYR-GCK MFQTLIRR-PLWWAGTAAAIAGFVFQALALANGSLLLVQPILVSALLFAL
MSMEG_6539|M.smegmatis_MC2_155 MLRTLLRR-KLWWAGTISAVMGYGFQALALGFGSLLLVQPVLVSALLFAL
TH_3271|M.thermoresistible__bu MIATLVRR-RLWWIGTGAAVAGYALQAAALAFGSLILVQPILVSALLFAL
MAB_2553|M.abscessus_ATCC_1997 KSTVAAALTPAFIAGMVLDLVGFAGSLVSARLIPLFLSQTIMSANLAVTA
: * : . . : .:.* ..: : .:
Mb2748c|M.bovis_AF2122/97 LIDARLTHHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVV
Rv2729c|M.tuberculosis_H37Rv LIDARLTHHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVV
MMAR_1983|M.marinum_M PIDSWLTQHRITAREWMWAILLAGAVAVIVTAGDPTAGHARAPLSTWAVV
MUL_3372|M.ulcerans_Agy99 PIYARVTRRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVV
MAV_1660|M.avium_104 PINARLSHRAVTAGEWVWAALLTAAVTVVVVVGNPQTGHAGAPLRTWAVV
Mvan_5745|M.vanbaalenii_PYR-1 PLSARLAHRRVTRAEWAWAVLLTLALAVFVVLAKASPGDYEASLSTSAVV
Mflv_1077|M.gilvum_PYR-GCK PLSARLAHRKVSRGEWAWAVLLTVALAVFVVLAKASPGDYEASLTTSIMV
MSMEG_6539|M.smegmatis_MC2_155 PLSARLARRTVSRADWMWALLLTGALTVFVLLARTSTGTYSVSVSTTVTV
TH_3271|M.thermoresistible__bu PLSARLGARRVSRGEWAWAAVLTVALAAFVLIAKPKPGDYQASIPGTVVV
MAB_2553|M.abscessus_ATCC_1997 VLGIAVLGVRLQRRDWLAICAVLLSLCVLAATAGPRGEDSAPPAIHWGVL
: : :* : :: ... . . . :
Mb2748c|M.bovis_AF2122/97 AVVVVPAVVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELG
Rv2729c|M.tuberculosis_H37Rv AVVVVPAVVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELG
MMAR_1983|M.marinum_M AAVMIPALVVCVVAARVTSGALSAVLLAVSSAAVLAVFTVFTKGVVALIG
MUL_3372|M.ulcerans_Agy99 ASVLGPVMVFCVLGARIWSGSVAAVLLAVVSGCSLALFAVLTKAVVEVVG
MAV_1660|M.avium_104 ALVLGPLLAACVVAGRVRGGAVAAVLFAFVSGSLWGVFAVLTKEVMARLG
Mvan_5745|M.vanbaalenii_PYR-1 AVVCTVAVLACVIVATRIAGWIRAVLLAVAVGVLFGVVAVLTKLVMHVLT
Mflv_1077|M.gilvum_PYR-GCK AVVCTVAVLACVIVAARFVGWVRAVLLAVAVGVLFGVVAVLTKLVMHMLV
MSMEG_6539|M.smegmatis_MC2_155 AVVCTSVVALCVVLATRSSNWRRAVLLAAAVGVMFGVVAVLTKIVMHLVA
TH_3271|M.thermoresistible__bu TVACVAGVTVCVVLAVRSLGWRRALLLATAVGVLFGVVAVLTKVWLHKLF
MAB_2553|M.abscessus_ATCC_1997 TVSIS--VLLTGIALIRLLGTRAAIPAGLLAGILYGGMAVAVR-VVGGVD
: : : . *: . . . .:* .: : :
Mb2748c|M.bovis_AF2122/97 -EGFATLIRTPELYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVI
Rv2729c|M.tuberculosis_H37Rv -EGFATLIRTPALYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVI
MMAR_1983|M.marinum_M -TGFGPLVRAPEFYAWMTVLPIGLMLQQSSLRAGSLTASLPTITVARPVI
MUL_3372|M.ulcerans_Agy99 -GGAGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLM
MAV_1660|M.avium_104 -QGVGVVTRTPELYACILVALGGVVWSQAAFRAGPLTASMPTLQVSQPVV
Mvan_5745|M.vanbaalenii_PYR-1 NEGFVAVLTTPVLYLLALLGVVATLLQQSAFHAGSLQTSVPTMLVLEPMI
Mflv_1077|M.gilvum_PYR-GCK HEGLVAVLTAPVLYLLALLGVVAMLIQQSAFHAGSLQTSVPTMLVLEPVI
MSMEG_6539|M.smegmatis_MC2_155 DGDALATFTTPALYLVVVLGVLATLLQQSAFHAGSLQTSVPTMLVLEPVV
TH_3271|M.thermoresistible__bu TGGVAVGVTSPLLYLLILLGVLATLLQQSAFHAGSLQASVPTMLVLEPVV
MAB_2553|M.abscessus_ATCC_1997 PLSLTVLLADPAAYGVVIAGVGGFYLFTVALQIGSVNGAAAALVVGETVV
. * * . ::: *.: : .:: * ..::
Mb2748c|M.bovis_AF2122/97 ASVLGITVLDEVLHTGRVALVALVAVVVVVVVATVALAR---DEVAMMTV
Rv2729c|M.tuberculosis_H37Rv ASVLGITVLDEVLHTGRVALVALVAAVVVVVVATVALAR---DEVAMMTV
MMAR_1983|M.marinum_M ASLLGVTVLDEVLQTGDLGVFVLLVAVAVVIVATVALAR---DEAAMMAP
MUL_3372|M.ulcerans_Agy99 GAVLGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAV
MAV_1660|M.avium_104 ASVLGVVVLGETLDTGRAGTVALLVAVVVMTAAIIKLAR--VEAVATRDR
Mvan_5745|M.vanbaalenii_PYR-1 AVILGAVVLGEHLNAGRWDAVALVVSTVAMVAGTIALGR---DEGAYEEQ
Mflv_1077|M.gilvum_PYR-GCK AVVLGAVVLGEHLNAGHWDLVAIAVATIAMAAGTVALGR---GEGAYEEQ
MSMEG_6539|M.smegmatis_MC2_155 AVLLGSVVLGEHLSIAGWQPVALTLAIAAMIAATIALGR---DEGAYEET
TH_3271|M.thermoresistible__bu AVALGAAVLGEHLDINGWEPVPLALAGAAMFAATVALGR---NEGAYEER
MAB_2553|M.abscessus_ATCC_1997 PGVIGVVLLGDSARPGMGWLVAVAFLGAVVSAVAVAVFG-----AAEHSR
:* .:*.: . : : . : : *
Mb2748c|M.bovis_AF2122/97 SAGELGAAG-QLAVR---------------------
Rv2729c|M.tuberculosis_H37Rv SAGELGAAG-QLAVR---------------------
MMAR_1983|M.marinum_M -ADNLNAAG-QLAMP---------------------
MUL_3372|M.ulcerans_Agy99 ESGHIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG
MAV_1660|M.avium_104 AEAQLHQPA---------------------------
Mvan_5745|M.vanbaalenii_PYR-1 LEADLAQKAQAASGNG--------------------
Mflv_1077|M.gilvum_PYR-GCK LEAD-QRTAQAASKSG--------------------
MSMEG_6539|M.smegmatis_MC2_155 LEAEMEAKTVTG------------------------
TH_3271|M.thermoresistible__bu LEVAALAQQSRSQQVRT-------------------
MAB_2553|M.abscessus_ATCC_1997 PVAPDPAR----------------------------