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M. tuberculosis H37Rv Rv2729c (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE VALINE AND LEUCINE RICH PROTEIN
coordinates: 3041570 - 3042475
length: 301

ASVEFATILALGAALLAGIGYVTLQRSARQVTAEEYVGHFTLFHLSLRHALWWLGSLAAVASFTLQAIAL
TMGSVVLVQSLQATALLFALLIDARLTHHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVV
AVVVVPAVVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELGEGFATLIRTPALYAWILVLP
IGLMLQQSSLRVGALTASLPTITVARPVIASVLGITVLDEVLHTGRVALVALVAAVVVVVVATVALARDE
VAMMTVSAGELGAAGQLAVR*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv2729c - - 100% (301) PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE VALINE AND LEUCINE RICH PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2748c - 1e-159 99.00% (301) hypothetical protein Mb2748c
M. gilvum PYR-GCK Mflv_3964 - 3e-73 52.98% (285) hypothetical protein Mflv_3964
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_2553 - 7e-09 22.97% (283) putative integral membrane protein
M. marinum M MMAR_1983 - 1e-117 73.67% (300) hypothetical protein MMAR_1983
M. avium 104 MAV_3622 - 1e-76 52.46% (284) hypothetical protein MAV_3622
M. smegmatis MC2 155 MSMEG_2732 - 1e-79 58.54% (287) hypothetical protein MSMEG_2732
M. thermoresistible (build 8) TH_3271 - 3e-43 40.65% (278) PUTATIVE putative conserved hypothetical protein
M. ulcerans Agy99 MUL_3372 - 8e-80 53.92% (293) hypothetical protein MUL_3372
M. vanbaalenii PYR-1 Mvan_2432 - 1e-72 53.12% (288) hypothetical protein Mvan_2432

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3964|M.gilvum_PYR-GCK          -MGEADIAVVLALAAALFMAVG-DVIHQRSAHEITDEP-VGHLELFLKLL
Mvan_2432|M.vanbaalenii_PYR-1       -MAKADLAALLALAAAFFMAVG-DVIHQRSARGVTDEP-IGHLELFGRLL
MSMEG_2732|M.smegmatis_MC2_155      -MNRADIAALLALGAALCIAIG-DVIHQRSAHDVTDDS-VSHLGLFKRLL
Rv2729c|M.tuberculosis_H37Rv        -MASVEFATILALGAALLAGIG-YVTLQRSARQVTAEEYVGHFTLFHLSL
Mb2748c|M.bovis_AF2122/97           -MASVEFATILALGAALLAGIG-YVTLQRSARQVTAEEYVGHLTLFHLSL
MMAR_1983|M.marinum_M               -MANVEVSASLALGAALLAGVG-YVVLQRSAQQVTEDE-VGHFTLLHLSL
MAV_3622|M.avium_104                -MSKVDVAALIALCAALASAVG-DVIRQRSAHEITDKP-VGHLELFRMSL
MUL_3372|M.ulcerans_Agy99           -MTTTEIAAVLALGAAFASALG-NVTRQRSAQEITDEQ-VGHLELFWLSL
TH_3271|M.thermoresistible__bu      -VLGQGLAVLLAVCAAVFAAVG-IVVRQRATMDVPPEKGVSTVMIATLVR
MAB_2553|M.abscessus_ATCC_1997      MLIGIAAAMLACFGYGTASVLQGYGARQSSTEVGVAADHGPSLKSTVAAA
                                     :     :   ..  .    :      * ::           .       

Mflv_3964|M.gilvum_PYR-GCK          RDGRWWLGSGVAAMGFACQAAALGLGSVLLVQALLVTSLLFALPLSARLS
Mvan_2432|M.vanbaalenii_PYR-1       RDGRWWVGSGTAAAGFVLQAAALGLGSVLLVQALLVTSLLFALPISARLS
MSMEG_2732|M.smegmatis_MC2_155      RDGRWWLGSGVAAAGFALQAAALGLGSVLLVQALLVTSLLFALPINARLT
Rv2729c|M.tuberculosis_H37Rv        RHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARLT
Mb2748c|M.bovis_AF2122/97           RHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARLT
MMAR_1983|M.marinum_M               RHGQWWLGSAAALSSFTLQAIALTMGSVVLVQSLQATALLFALPIDSWLT
MAV_3622|M.avium_104                RDTRWWLGGLAAITNYSLQAAALAWGSVVLVTALQVTALLFALPLYARLA
MUL_3372|M.ulcerans_Agy99           RDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPIYARVT
TH_3271|M.thermoresistible__bu      RR-LWWIGTGAAVAGYALQAAALAFGSLILVQPILVSALLFALPLSARLG
MAB_2553|M.abscessus_ATCC_1997      LTPAFIAGMVLDLVGFAGSLVSARLIPLFLSQTIMSANLAVTAVLGIAVL
                                        :  *      .:  .  :    .:.*  .:  : * .:  :   : 

Mflv_3964|M.gilvum_PYR-GCK          HRRVTRWEWIWAVLLAGAVAVIVTVGNPTEGATRASLQTWIEVAAVLGPV
Mvan_2432|M.vanbaalenii_PYR-1       HRRVTRWELLWAAVLAGAVAVIVTVGNPTEGASRASLETWLGVATVLGPL
MSMEG_2732|M.smegmatis_MC2_155      RRRVTRWEWMWAALLAGAVAVIVTVGNPTAGHARAPWEAWTLVLAVLGPA
Rv2729c|M.tuberculosis_H37Rv        HHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVPA
Mb2748c|M.bovis_AF2122/97           HHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVPA
MMAR_1983|M.marinum_M               QHRITAREWMWAILLAGAVAVIVTAGDPTAGHARAPLSTWAVVAAVMIPA
MAV_3622|M.avium_104                HQRIKPREWAWALILAAALAVVIIVGDPASGKQRAPLHIWVIVALVMVPV
MUL_3372|M.ulcerans_Agy99           RRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVASVLGPV
TH_3271|M.thermoresistible__bu      ARRVSRGEWAWAAVLTVALAAFVLIAKPKPGDYQASIPGTVVVTVACVAG
MAB_2553|M.abscessus_ATCC_1997      GVRLQRRDWLAICAVLLSLCVLAATAGPRGEDSAPPAIHWGVLTVSIS--
                                      *    :      :  ::...   . *       .      :       

Mflv_3964|M.gilvum_PYR-GCK          LVLCLVGARMSSGA-MSAVLTGVVSGALWGVFAVLTKTVVHRLDVTSLAG
Mvan_2432|M.vanbaalenii_PYR-1       LALCVVGATVWSGP-ISAVLMAVVSGALWGLFAVLTKAVVHRLDVTSLAG
MSMEG_2732|M.smegmatis_MC2_155      VAVCLVGARIFTGA-RSAVLLALVSGALWGVFAVLTKGVVNHLLVHSWGG
Rv2729c|M.tuberculosis_H37Rv        VVLCVVGARIASGS-LSAVLLAVASSATLAVFTVLTKGVVTELG----EG
Mb2748c|M.bovis_AF2122/97           VVLCVVGARIASGS-LSAVLLAVASSATLAVFTVLTKGVVTELG----EG
MMAR_1983|M.marinum_M               LVVCVVAARVTSGA-LSAVLLAVSSAAVLAVFTVFTKGVVALIG----TG
MAV_3622|M.avium_104                LVACVVAARRWAGSPFAAVLLAVVAGSSLALFAVLTKGVVEMSE----HS
MUL_3372|M.ulcerans_Agy99           MVFCVLGARIWSGS-VAAVLLAVVSGCSLALFAVLTKAVVEVVG----GG
TH_3271|M.thermoresistible__bu      VTVCVVLAVRSLGW-RRALLLATAVGVLFGVVAVLTKVWLHKLFT---GG
MAB_2553|M.abscessus_ATCC_1997      VLLTGIALIRLLGT-RAAIPAGLLAGILYGGMAVAVRVVGGVDP----LS
                                    :    :      *    *:  .   .   . .:* .:            .

Mflv_3964|M.gilvum_PYR-GCK          VVELLSTPELYAWAVVGILGTSTQQAAFRAGSLTASLPTMTVTEPLVGCA
Mvan_2432|M.vanbaalenii_PYR-1       VTELLRTPELYAWAVVALLGTSTQQAAFRAGALTASLPTMTVAEPVVASV
MSMEG_2732|M.smegmatis_MC2_155      VFTLLRVPELYVWILVAIAGTVVQQSSFRAGALTASLPTMTVTEPVVASV
Rv2729c|M.tuberculosis_H37Rv        FATLIRTPALYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASV
Mb2748c|M.bovis_AF2122/97           FATLIRTPELYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASV
MMAR_1983|M.marinum_M               FGPLVRAPEFYAWMTVLPIGLMLQQSSLRAGSLTASLPTITVARPVIASL
MAV_3622|M.avium_104                LVGVLTSPEFVPWLLVALTGMIFQQSAFRAGALTASLPTMTVAKPVVAGL
MUL_3372|M.ulcerans_Agy99           AGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMGAV
TH_3271|M.thermoresistible__bu      VAVGVTSPLLYLLILLGVLATLLQQSAFHAGSLQASVPTMLVLEPVVAVA
MAB_2553|M.abscessus_ATCC_1997      LTVLLADPAAYGVVIAGVGGFYLFTVALQIGSVNGAAAALVVGETVVPGV
                                        .  *           .      ::: *:: .: .:: * ..::   

Mflv_3964|M.gilvum_PYR-GCK          LGVVVLGETMRPGETGWVLLIAAAVTVVVATAALARGEATDLQPATV---
Mvan_2432|M.vanbaalenii_PYR-1       LSVVVLGETLRPGAAGWATLVVAVAAMVTATAALARGEATVKEPSG----
MSMEG_2732|M.smegmatis_MC2_155      LGIVVLGETLRPGDAGWVTLVAAIAVMVAATVALARGEAAE-EPATVPAH
Rv2729c|M.tuberculosis_H37Rv        LGITVLDEVLHTGRVALVALVAAVVVVVVATVALARDEVAMMTVSAGELG
Mb2748c|M.bovis_AF2122/97           LGITVLDEVLHTGRVALVALVAVVVVVVVATVALARDEVAMMTVSAGELG
MMAR_1983|M.marinum_M               LGVTVLDEVLQTGDLGVFVLLVAVAVVIVATVALARDEAAMMAP-ADNLN
MAV_3622|M.avium_104                LGVLVLDETLNAHGPKAFVLVGAVAVVIVATIALARGEAASINRPEPGPG
MUL_3372|M.ulcerans_Agy99           LGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVESG
TH_3271|M.thermoresistible__bu      LGAAVLGEHLDINGWEPVPLALAGAAMFAATVALGRNEGAYEERLEVAAL
MAB_2553|M.abscessus_ATCC_1997      IGVVLLGDSARPG-MGWLVAVAFLGAVVSAVAVAVFGAAEHSRPVAPDPA
                                    :.  :*.:                  :. *. .   .             

Mflv_3964|M.gilvum_PYR-GCK          -----------------------------------
Mvan_2432|M.vanbaalenii_PYR-1       -----------------------------------
MSMEG_2732|M.smegmatis_MC2_155      -----------------------------------
Rv2729c|M.tuberculosis_H37Rv        ----------------------AAGQLAVR-----
Mb2748c|M.bovis_AF2122/97           ----------------------AAGQLAVR-----
MMAR_1983|M.marinum_M               ----------------------AAGQLAMP-----
MAV_3622|M.avium_104                SAPRKARDATADVAADDDDTGPFSGRLLVADSSRW
MUL_3372|M.ulcerans_Agy99           HIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG--
TH_3271|M.thermoresistible__bu      AQ--------------------QSRSQQVRT----
MAB_2553|M.abscessus_ATCC_1997      R----------------------------------

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv2729c	-	-	100% (301)	PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE VALINE AND LEUCINE RICH PROTEIN