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VPRTEIIAALLALSSALCVATGDVLQQRAAHCITDRELGPVELFAGLLRSQRWWWGAVLLLASIGLQAAA LGGGSVLLVQALLMFSVLFALPINARLSHRAVTAGEWVWAALLTAAVTVVVVVGNPQTGHAGAPLRTWAV VALVLGPLLAACVVAGRVRGGAVAAVLFAFVSGSLWGVFAVLTKEVMARLGQGVGVVTRTPELYACILVA LGGVVWSQAAFRAGPLTASMPTLQVSQPVVASVLGVVVLGETLDTGRAGTVALLVAVVVMTAAIIKLARV EAVATRDRAEAQLHQPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1660 | - | - | 100% (297) | hypothetical protein MAV_1660 |
| M. avium 104 | MAV_2125 | - | 2e-79 | 53.17% (284) | hypothetical protein MAV_2125 |
| M. avium 104 | MAV_3622 | - | 6e-68 | 49.82% (279) | hypothetical protein MAV_3622 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2748c | - | 5e-65 | 49.09% (275) | hypothetical protein Mb2748c |
| M. gilvum PYR-GCK | Mflv_3964 | - | 2e-77 | 55.71% (280) | hypothetical protein Mflv_3964 |
| M. tuberculosis H37Rv | Rv2729c | - | 2e-64 | 49.09% (275) | hypothetical protein Rv2729c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2553 | - | 3e-10 | 23.20% (194) | putative integral membrane protein |
| M. marinum M | MMAR_1984 | - | 2e-72 | 50.34% (294) | hypothetical protein MMAR_1984 |
| M. smegmatis MC2 155 | MSMEG_2732 | - | 1e-84 | 59.64% (280) | hypothetical protein MSMEG_2732 |
| M. thermoresistible (build 8) | TH_3271 | - | 6e-45 | 40.35% (285) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3372 | - | 2e-72 | 50.34% (294) | hypothetical protein MUL_3372 |
| M. vanbaalenii PYR-1 | Mvan_2432 | - | 5e-80 | 59.64% (280) | hypothetical protein Mvan_2432 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3964|M.gilvum_PYR-GCK --MGEAD-IAVVLALAAALFMAVGDVIHQRSAHEITDEP-VGHLELFLKL
Mvan_2432|M.vanbaalenii_PYR-1 --MAKAD-LAALLALAAAFFMAVGDVIHQRSARGVTDEP-IGHLELFGRL
MSMEG_2732|M.smegmatis_MC2_155 --MNRAD-IAALLALGAALCIAIGDVIHQRSAHDVTDDS-VSHLGLFKRL
MAV_1660|M.avium_104 --MPRTEIIAALLALSSALCVATGDVLQQRAAHCITDRE-LGPVELFAGL
Mb2748c|M.bovis_AF2122/97 --MASVE-FATILALGAALLAGIGYVTLQRSARQVTAEEYVGHLTLFHLS
Rv2729c|M.tuberculosis_H37Rv --MASVE-FATILALGAALLAGIGYVTLQRSARQVTAEEYVGHFTLFHLS
MMAR_1984|M.marinum_M --MTTTE-IAAVLALGAAFASALGNVTRQRSAQEITDEQ-VGHLELFWLS
MUL_3372|M.ulcerans_Agy99 --MTTTE-IAAVLALGAAFASALGNVTRQRSAQEITDEQ-VGHLELFWLS
TH_3271|M.thermoresistible__bu --VLGQG-LAVLLAVCAAVFAAVGIVVRQRATMDVPPEKGVSTV-MIATL
MAB_2553|M.abscessus_ATCC_1997 MLIGIAAAMLACFGYGTASVLQGYGARQSSTEVGVAADHGPSLKSTVAAA
: : . :. :* . . : :. . .
Mflv_3964|M.gilvum_PYR-GCK LRDGRWWLGSGVAAMGFACQAAALGLGSVLLVQALLVTSLLFALPLSARL
Mvan_2432|M.vanbaalenii_PYR-1 LRDGRWWVGSGTAAAGFVLQAAALGLGSVLLVQALLVTSLLFALPISARL
MSMEG_2732|M.smegmatis_MC2_155 LRDGRWWLGSGVAAAGFALQAAALGLGSVLLVQALLVTSLLFALPINARL
MAV_1660|M.avium_104 LRSQRWWWGAVLLLASIGLQAAALGGGSVLLVQALLMFSVLFALPINARL
Mb2748c|M.bovis_AF2122/97 LRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARL
Rv2729c|M.tuberculosis_H37Rv LRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARL
MMAR_1984|M.marinum_M LRDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPIYARV
MUL_3372|M.ulcerans_Agy99 LRDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPIYARV
TH_3271|M.thermoresistible__bu VRRRLWWIGTGAAVAGYALQAAALAFGSLILVQPILVSALLFALPLSARL
MAB_2553|M.abscessus_ATCC_1997 LTP-AFIAGMVLDLVGFAGSLVSARLIPLFLSQTIMSANLAVTAVLGIAV
: : * . . : .:.* ..: : .: : :
Mflv_3964|M.gilvum_PYR-GCK SHRRVTRWEWIWAVLLAGAVAVIVTVGNPTEGATRASLQTWIEVAAVLGP
Mvan_2432|M.vanbaalenii_PYR-1 SHRRVTRWELLWAAVLAGAVAVIVTVGNPTEGASRASLETWLGVATVLGP
MSMEG_2732|M.smegmatis_MC2_155 TRRRVTRWEWMWAALLAGAVAVIVTVGNPTAGHARAPWEAWTLVLAVLGP
MAV_1660|M.avium_104 SHRAVTAGEWVWAALLTAAVTVVVVVGNPQTGHAGAPLRTWAVVALVLGP
Mb2748c|M.bovis_AF2122/97 THHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVP
Rv2729c|M.tuberculosis_H37Rv THHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVP
MMAR_1984|M.marinum_M TRRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVASVLGP
MUL_3372|M.ulcerans_Agy99 TRRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVASVLGP
TH_3271|M.thermoresistible__bu GARRVSRGEWAWAAVLTVALAAFVLIAKPKPGDYQASIPGTVVVTVACVA
MAB_2553|M.abscessus_ATCC_1997 LGVRLQRRDWLAICAVLLSLCVLAATAGPRGEDSAPPAIHWGVLTVSIS-
: : :: ... . * . :
Mflv_3964|M.gilvum_PYR-GCK VLVLCLVGARMSSGAMSAVLTGVVSGALWGVFAVLTKTVVHRLDVTSLAG
Mvan_2432|M.vanbaalenii_PYR-1 LLALCVVGATVWSGPISAVLMAVVSGALWGLFAVLTKAVVHRLDVTSLAG
MSMEG_2732|M.smegmatis_MC2_155 AVAVCLVGARIFTGARSAVLLALVSGALWGVFAVLTKGVVNHLLVHSWGG
MAV_1660|M.avium_104 LLAACVVAGRVRGGAVAAVLFAFVSGSLWGVFAVLTKEVMARLG----QG
Mb2748c|M.bovis_AF2122/97 AVVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELG----EG
Rv2729c|M.tuberculosis_H37Rv AVVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELG----EG
MMAR_1984|M.marinum_M VMVFCVLGARIWSGSVAAVLLAVVSGCSLALFAVLTKAVVEVVG----GG
MUL_3372|M.ulcerans_Agy99 VMVFCVLGARIWSGSVAAVLLAVVSGCSLALFAVLTKAVVEVVG----GG
TH_3271|M.thermoresistible__bu GVTVCVVLAVRSLGWRRALLLATAVGVLFGVVAVLTKVWLHKLFT---GG
MAB_2553|M.abscessus_ATCC_1997 -VLLTGIALIRLLGTRAAIPAGLLAGILYGGMAVAVRVVGGVDP----LS
: : * *: . . . .:* .: .
Mflv_3964|M.gilvum_PYR-GCK VVELLSTPELYAWAVVGILGTSTQQAAFRAGSLTASLPTMTVTEPLVGCA
Mvan_2432|M.vanbaalenii_PYR-1 VTELLRTPELYAWAVVALLGTSTQQAAFRAGALTASLPTMTVAEPVVASV
MSMEG_2732|M.smegmatis_MC2_155 VFTLLRVPELYVWILVAIAGTVVQQSSFRAGALTASLPTMTVTEPVVASV
MAV_1660|M.avium_104 VGVVTRTPELYACILVALGGVVWSQAAFRAGPLTASMPTLQVSQPVVASV
Mb2748c|M.bovis_AF2122/97 FATLIRTPELYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASV
Rv2729c|M.tuberculosis_H37Rv FATLIRTPALYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASV
MMAR_1984|M.marinum_M AGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMGAV
MUL_3372|M.ulcerans_Agy99 AGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMGAV
TH_3271|M.thermoresistible__bu VAVGVTSPLLYLLILLGVLATLLQQSAFHAGSLQASVPTMLVLEPVVAVA
MAB_2553|M.abscessus_ATCC_1997 LTVLLADPAAYGVVIAGVGGFYLFTVALQIGSVNGAAAALVVGETVVPGV
* * . ::: *.: .: .:: * ..:: .
Mflv_3964|M.gilvum_PYR-GCK LGVVVLGETMRPGETGWVLLIAAAVTVVVATAALARGEATDLQPATV---
Mvan_2432|M.vanbaalenii_PYR-1 LSVVVLGETLRPGAAGWATLVVAVAAMVTATAALARGEATVKEPSG----
MSMEG_2732|M.smegmatis_MC2_155 LGIVVLGETLRPGDAGWVTLVAAIAVMVAATVALARGEAAE-EPATVPAH
MAV_1660|M.avium_104 LGVVVLGETLDTGRAGTVALLVAVVVMTAAIIKLARVEAVATRDRAEAQL
Mb2748c|M.bovis_AF2122/97 LGITVLDEVLHTGRVALVALVAVVVVVVVATVALAR---DEVAMMTVSAG
Rv2729c|M.tuberculosis_H37Rv LGITVLDEVLHTGRVALVALVAAVVVVVVATVALAR---DEVAMMTVSAG
MMAR_1984|M.marinum_M LGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVESG
MUL_3372|M.ulcerans_Agy99 LGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVESG
TH_3271|M.thermoresistible__bu LGAAVLGEHLDINGWEPVPLALAGAAMFAATVALGRNEGAYEERLEVAAL
MAB_2553|M.abscessus_ATCC_1997 IGVVLLGDSARPG-MGWLVAVAFLGAVVSAVAVAVFGAAEHSRPVAPDPA
:. .:*.: : *
Mflv_3964|M.gilvum_PYR-GCK ---------------------------------
Mvan_2432|M.vanbaalenii_PYR-1 ---------------------------------
MSMEG_2732|M.smegmatis_MC2_155 ---------------------------------
MAV_1660|M.avium_104 HQPA-----------------------------
Mb2748c|M.bovis_AF2122/97 ELGAAG-QLAVR---------------------
Rv2729c|M.tuberculosis_H37Rv ELGAAG-QLAVR---------------------
MMAR_1984|M.marinum_M HIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG
MUL_3372|M.ulcerans_Agy99 HIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG
TH_3271|M.thermoresistible__bu AQQSRSQQVRT----------------------
MAB_2553|M.abscessus_ATCC_1997 R--------------------------------