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VGIVVRQRATLDVPAEDGISAVMFQTLIRRPLWWAGTAAAIAGFVFQALALANGSLLLVQPILVSALLFA LPLSARLAHRKVSRGEWAWAVLLTVALAVFVVLAKASPGDYEASLTTSIMVAVVCTVAVLACVIVAARFV GWVRAVLLAVAVGVLFGVVAVLTKLVMHMLVHEGLVAVLTAPVLYLLALLGVVAMLIQQSAFHAGSLQTS VPTMLVLEPVIAVVLGAVVLGEHLNAGHWDLVAIAVATIAMAAGTVALGRGEGAYEEQLEADQRTAQAAS KSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1077 | - | - | 100% (283) | hypothetical protein Mflv_1077 |
| M. gilvum PYR-GCK | Mflv_3964 | - | 8e-55 | 45.28% (265) | hypothetical protein Mflv_3964 |
| M. gilvum PYR-GCK | Mflv_3133 | - | 5e-06 | 29.51% (244) | hypothetical protein Mflv_3133 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2748c | - | 7e-48 | 41.89% (265) | hypothetical protein Mb2748c |
| M. tuberculosis H37Rv | Rv2729c | - | 2e-48 | 42.26% (265) | hypothetical protein Rv2729c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2553 | - | 4e-13 | 25.86% (263) | putative integral membrane protein |
| M. marinum M | MMAR_1984 | - | 7e-48 | 39.93% (283) | hypothetical protein MMAR_1984 |
| M. avium 104 | MAV_3622 | - | 6e-50 | 43.02% (265) | hypothetical protein MAV_3622 |
| M. smegmatis MC2 155 | MSMEG_6539 | - | 2e-99 | 67.28% (272) | hypothetical protein MSMEG_6539 |
| M. thermoresistible (build 8) | TH_3271 | - | 1e-100 | 65.84% (281) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3372 | - | 4e-48 | 39.93% (283) | hypothetical protein MUL_3372 |
| M. vanbaalenii PYR-1 | Mvan_5745 | - | 1e-132 | 85.21% (284) | hypothetical protein Mvan_5745 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2748c|M.bovis_AF2122/97 ------MASVEFATILALGAALLAGIG-YVTLQRSARQVTAEEYVGHLTL
Rv2729c|M.tuberculosis_H37Rv ------MASVEFATILALGAALLAGIG-YVTLQRSARQVTAEEYVGHFTL
MMAR_1984|M.marinum_M ------MTTTEIAAVLALGAAFASALG-NVTRQRSAQEITDEQ-VGHLEL
MUL_3372|M.ulcerans_Agy99 ------MTTTEIAAVLALGAAFASALG-NVTRQRSAQEITDEQ-VGHLEL
MAV_3622|M.avium_104 ------MSKVDVAALIALCAALASAVG-DVIRQRSAHEITDKP-VGHLEL
Mflv_1077|M.gilvum_PYR-GCK -------------------------MG-IVVRQRATLDVPAEDGISAVMF
Mvan_5745|M.vanbaalenii_PYR-1 MCCPCRVIGHGVTVLLAFLAAVFLAVG-IVVRQRATLDVPAEHGVSPVMI
MSMEG_6539|M.smegmatis_MC2_155 ------MLGNSIAVLLALCAAIFMAVG-IVVRQRATLDVPAGKGVSTVML
TH_3271|M.thermoresistible__bu ------VLGQGLAVLLAVCAAVFAAVG-IVVRQRATMDVPPEKGVSTVMI
MAB_2553|M.abscessus_ATCC_1997 -----MLIGIAAAMLACFGYGTASVLQGYGARQSSTEVGVAADHGPSLKS
: * :: .
Mb2748c|M.bovis_AF2122/97 FHLSLRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLI
Rv2729c|M.tuberculosis_H37Rv FHLSLRHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLI
MMAR_1984|M.marinum_M FWLSLRDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPI
MUL_3372|M.ulcerans_Agy99 FWLSLRDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPI
MAV_3622|M.avium_104 FRMSLRDTRWWLGGLAAITNYSLQAAALAWGSVVLVTALQVTALLFALPL
Mflv_1077|M.gilvum_PYR-GCK QTL-IRRPLWWAGTAAAIAGFVFQALALANGSLLLVQPILVSALLFALPL
Mvan_5745|M.vanbaalenii_PYR-1 QTL-VRRPLWWAGTASAVAGFVFQALALANGSLLLVQPILVSALLFALPL
MSMEG_6539|M.smegmatis_MC2_155 RTL-LRRKLWWAGTISAVMGYGFQALALGFGSLLLVQPVLVSALLFALPL
TH_3271|M.thermoresistible__bu ATL-VRRRLWWIGTGAAVAGYALQAAALAFGSLILVQPILVSALLFALPL
MAB_2553|M.abscessus_ATCC_1997 TVAAALTPAFIAGMVLDLVGFAGSLVSARLIPLFLSQTIMSANLAVTAVL
: * : .: . : .:.* .: : * .: :
Mb2748c|M.bovis_AF2122/97 DARLTHHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAV
Rv2729c|M.tuberculosis_H37Rv DARLTHHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAV
MMAR_1984|M.marinum_M YARVTRRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVAS
MUL_3372|M.ulcerans_Agy99 YARVTRRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVAS
MAV_3622|M.avium_104 YARLAHQRIKPREWAWALILAAALAVVIIVGDPASGKQRAPLHIWVIVAL
Mflv_1077|M.gilvum_PYR-GCK SARLAHRKVSRGEWAWAVLLTVALAVFVVLAKASPGDYEASLTTSIMVAV
Mvan_5745|M.vanbaalenii_PYR-1 SARLAHRRVTRAEWAWAVLLTLALAVFVVLAKASPGDYEASLSTSAVVAV
MSMEG_6539|M.smegmatis_MC2_155 SARLARRTVSRADWMWALLLTGALTVFVLLARTSTGTYSVSVSTTVTVAV
TH_3271|M.thermoresistible__bu SARLGARRVSRGEWAWAAVLTVALAAFVLIAKPKPGDYQASIPGTVVVTV
MAB_2553|M.abscessus_ATCC_1997 GIAVLGVRLQRRDWLAICAVLLSLCVLAATAGPR-GEDSAPPAIHWGVLT
: :* : :: .. . . * . *
Mb2748c|M.bovis_AF2122/97 VVVPAVVLCVVGARIASGS-LSAVLLAVASSATLAVFTVLTKGVVTELGE
Rv2729c|M.tuberculosis_H37Rv VVVPAVVLCVVGARIASGS-LSAVLLAVASSATLAVFTVLTKGVVTELGE
MMAR_1984|M.marinum_M VLGPVMVFCVLGARIWSGS-VAAVLLAVVSGCSLALFAVLTKAVVEVVGG
MUL_3372|M.ulcerans_Agy99 VLGPVMVFCVLGARIWSGS-VAAVLLAVVSGCSLALFAVLTKAVVEVVGG
MAV_3622|M.avium_104 VMVPVLVACVVAARRWAGSPFAAVLLAVVAGSSLALFAVLTKGVVEMSEH
Mflv_1077|M.gilvum_PYR-GCK VCTVAVLACVIVAARFVGW-VRAVLLAVAVGVLFGVVAVLTKLVMHMLVH
Mvan_5745|M.vanbaalenii_PYR-1 VCTVAVLACVIVATRIAGW-IRAVLLAVAVGVLFGVVAVLTKLVMHVLTN
MSMEG_6539|M.smegmatis_MC2_155 VCTSVVALCVVLATRSSNW-RRAVLLAAAVGVMFGVVAVLTKIVMHLVAD
TH_3271|M.thermoresistible__bu ACVAGVTVCVVLAVRSLGW-RRALLLATAVGVLFGVVAVLTKVWLHKLFT
MAB_2553|M.abscessus_ATCC_1997 VSISVLLTGIALIRLLGTR--AAIPAGLLAGILYGGMAVAVRVVGGVDPL
. : : *: . . . .:* .:
Mb2748c|M.bovis_AF2122/97 G-FATLIRTPELYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIA
Rv2729c|M.tuberculosis_H37Rv G-FATLIRTPALYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIA
MMAR_1984|M.marinum_M G-AGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMG
MUL_3372|M.ulcerans_Agy99 G-AGALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMG
MAV_3622|M.avium_104 S-LVGVLTSPEFVPWLLVALTGMIFQQSAFRAGALTASLPTMTVAKPVVA
Mflv_1077|M.gilvum_PYR-GCK EGLVAVLTAPVLYLLALLGVVAMLIQQSAFHAGSLQTSVPTMLVLEPVIA
Mvan_5745|M.vanbaalenii_PYR-1 EGFVAVLTTPVLYLLALLGVVATLLQQSAFHAGSLQTSVPTMLVLEPMIA
MSMEG_6539|M.smegmatis_MC2_155 GDALATFTTPALYLVVVLGVLATLLQQSAFHAGSLQTSVPTMLVLEPVVA
TH_3271|M.thermoresistible__bu GGVAVGVTSPLLYLLILLGVLATLLQQSAFHAGSLQASVPTMLVLEPVVA
MAB_2553|M.abscessus_ATCC_1997 S-LTVLLADPAAYGVVIAGVGGFYLFTVALQIGSVNGAAAALVVGETVVP
. * . : ::: *:: : .:: * ..::
Mb2748c|M.bovis_AF2122/97 SVLGITVLDEVLHTGRVALVALVAVVVVVVVATVALARDEVAMMTVSAGE
Rv2729c|M.tuberculosis_H37Rv SVLGITVLDEVLHTGRVALVALVAAVVVVVVATVALARDEVAMMTVSAGE
MMAR_1984|M.marinum_M AVLGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVE
MUL_3372|M.ulcerans_Agy99 AVLGMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVE
MAV_3622|M.avium_104 GLLGVLVLDETLNAHGPKAFVLVGAVAVVIVATIALARGEAASINRPEPG
Mflv_1077|M.gilvum_PYR-GCK VVLGAVVLGEHLNAGHWDLVAIAVATIAMAAGTVALGRGEGAYEEQLEAD
Mvan_5745|M.vanbaalenii_PYR-1 VILGAVVLGEHLNAGRWDAVALVVSTVAMVAGTIALGRDEGAYEEQLEAD
MSMEG_6539|M.smegmatis_MC2_155 VLLGSVVLGEHLSIAGWQPVALTLAIAAMIAATIALGRDEGAYEETLEAE
TH_3271|M.thermoresistible__bu VALGAAVLGEHLDINGWEPVPLALAGAAMFAATVALGRNEGAYEERLEVA
MAB_2553|M.abscessus_ATCC_1997 GVIGVVLLGDSARPGMGWLVAVAFLGAVVSAVAVAVFG-AAEHSRPVAPD
:* :*.: . :. : . ::*:
Mb2748c|M.bovis_AF2122/97 LG----------------------AAGQLAVR-----
Rv2729c|M.tuberculosis_H37Rv LG----------------------AAGQLAVR-----
MMAR_1984|M.marinum_M SGHIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG--
MUL_3372|M.ulcerans_Agy99 SGHIPATMPHRAVTMHFGPADDDVQTDRLRRAPAG--
MAV_3622|M.avium_104 PGSAPRKARDATADVAADDDDTGPFSGRLLVADSSRW
Mflv_1077|M.gilvum_PYR-GCK -QRTAQ------------------AASKSG-------
Mvan_5745|M.vanbaalenii_PYR-1 LAQKAQ------------------AASGNG-------
MSMEG_6539|M.smegmatis_MC2_155 MEAKTV------------------TG-----------
TH_3271|M.thermoresistible__bu ALAQQS------------------RSQQVRT------
MAB_2553|M.abscessus_ATCC_1997 PAR----------------------------------