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MRFAFKTSPQNTTWEQMLAVWQTADGIDVYESGWTFDHFYPIFSDPTGPCLEGWTTLTALAQATTRLRLG TLVTGVHYRHPAVLANMAAALDIISHGRLELGIGAGWNEEESSAYGIELGSVKERFDRFEEACAVLTGLL SQPSTTFDGKYYQLEDARNEPKGPQRPHPPICIGGSGEKRTLRITARYAQHWNFAGGTPEEFARKRDVLA AHCADIGRDPKEITLSAHLGLAPERDFGQVIENAAALAAEGLDLGIVYIAPPHDPAVLEPMAEAIRESGL IDG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5411 | - | - | 100% (283) | hypothetical protein MMAR_5411 |
| M. marinum M | MMAR_2729 | - | 7e-45 | 40.15% (269) | oxidoreductase |
| M. marinum M | MMAR_2559 | - | 1e-42 | 40.40% (250) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 7e-43 | 37.82% (275) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_1117 | - | 1e-138 | 80.85% (282) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 7e-43 | 37.82% (275) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00131 | - | 1e-15 | 30.48% (210) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4496c | - | 1e-140 | 81.88% (276) | luciferase-like monooxygenase |
| M. avium 104 | MAV_0169 | - | 1e-146 | 86.12% (281) | hypothetical protein MAV_0169 |
| M. smegmatis MC2 155 | MSMEG_6454 | - | 1e-141 | 82.44% (279) | hypothetical protein MSMEG_6454 |
| M. thermoresistible (build 8) | TH_4285 | - | 1e-137 | 80.36% (280) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_5034 | - | 1e-165 | 98.23% (283) | hypothetical protein MUL_5034 |
| M. vanbaalenii PYR-1 | Mvan_5695 | - | 1e-139 | 81.21% (282) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQ--TAEEYG-FDSVWLCD
Rv0791c|M.tuberculosis_H37Rv MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQ--TAEEYG-FDSVWLCD
MMAR_5411|M.marinum_M -----------MRFAFKTSPQNTTWEQMLAVWQ--TADGIDVYESGWTFD
MUL_5034|M.ulcerans_Agy99 -----------MRFAFKNSPQNTTWEQMLAVWQ--TADGIDVYESGWTFD
MAV_0169|M.avium_104 -----------MRFAFKTSPQNTTWAQMLAVWQ--AADDIDVYESGWTFD
Mflv_1117|M.gilvum_PYR-GCK -----------MRFAFKTSPQNTTWSDMLTVWK--AADDIDVFESGWTFD
Mvan_5695|M.vanbaalenii_PYR-1 -----------MRFAFKTSPQNTAWSDMLSVWK--AADDIDVFESGWTFD
MAB_4496c|M.abscessus_ATCC_199 -----------MRFAFKTSPQNTTWDDMLAIWK--VADDIEVFESGWTFD
MSMEG_6454|M.smegmatis_MC2_155 -----------MRFAFKTSPQNTTWADMLAIWK--AADNIDVFESGWTFD
TH_4285|M.thermoresistible__bu -----------MQFGFKTSPQNTTWQDMLSVWR--AADDIDVFESGWTFD
MLBr_00131|M.leprae_Br4923 --------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGD
: . . : : .: :* * *
Mb0815c|M.bovis_AF2122/97 HFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALA
Rv0791c|M.tuberculosis_H37Rv HFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALA
MMAR_5411|M.marinum_M HFYPIFS-----------------------------DPTGPCLEGWTTLT
MUL_5034|M.ulcerans_Agy99 HFYPIFS-----------------------------DPTGPCLEGWTTLT
MAV_0169|M.avium_104 HFYPIFS-----------------------------DSSGPCLEGWTTLT
Mflv_1117|M.gilvum_PYR-GCK HFYPIFS-----------------------------DPTGPCLEGWVTLT
Mvan_5695|M.vanbaalenii_PYR-1 HFYPIFS-----------------------------DPSGPCLEGWVTLT
MAB_4496c|M.abscessus_ATCC_199 HFYPIFS-----------------------------DPTGPCLEGWVTLT
MSMEG_6454|M.smegmatis_MC2_155 HFYPIFS-----------------------------DSAGPCLEGWTTLT
TH_4285|M.thermoresistible__bu HFYPIFS-----------------------------DPTGPCLEGWTTLT
MLBr_00131|M.leprae_Br4923 HLNALVPRSVATPKYLG-------------VAAKVVPKIDANYEPWTMLG
*: .: . . * *. *
Mb0815c|M.bovis_AF2122/97 ALSRDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAG
Rv0791c|M.tuberculosis_H37Rv ALSRDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAG
MMAR_5411|M.marinum_M ALAQATTR--LRLGTLVTGVHYRHPAVLANMAAALDIISHGRLELGIGAG
MUL_5034|M.ulcerans_Agy99 ALAQATTR--LRLGTLVTGIHYRHPAVLANMAAALDIISHGRLELGIGAG
MAV_0169|M.avium_104 ALAQATKR--LRLGTLVTGIHYRHPAVLANMAAAVDIISGGRLELGIGAG
Mflv_1117|M.gilvum_PYR-GCK ALAQATTR--LRVGVLVTGIHYRHPAVLANMASALDIVSGGRLELGIGAG
Mvan_5695|M.vanbaalenii_PYR-1 ALAQATTR--LRVGVLVTGIHYRHPAVLANMASALDIVSDGRLELGIGAG
MAB_4496c|M.abscessus_ATCC_199 ALAQATQR--LRVGVLVTGIHYRHPAVLANMASALDIVSGGRLELGIGAG
MSMEG_6454|M.smegmatis_MC2_155 ALAQATER--LRVGVLVTGIHYRHPAVLANMAAALDIISNGRLELGIGAG
TH_4285|M.thermoresistible__bu ALAQATTR--LRVGVLVTGIHYRHPAVLANMASALDIISAGRLELGIGAG
MLBr_00131|M.leprae_Br4923 NLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVG
*: . **:*. * *:*:* *: *:::.::: *: **:*.*
Mb0815c|M.bovis_AF2122/97 WFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTE--PNPTYAGRFYTL
Rv0791c|M.tuberculosis_H37Rv WFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTE--PNPTYAGRFYTL
MMAR_5411|M.marinum_M WNEEESSAYGIELGSVKERFDRFEEACAVLTGLLSQ--PSTTFDGKYYQL
MUL_5034|M.ulcerans_Agy99 WNEEESGAYGIELGSVKERFDRFEEACAVLTGLLSQ--PSTTFDGKYYQL
MAV_0169|M.avium_104 WNEEESGAYGIELGSIRERFDRFEEACAVLTSLLSQ--ETTDFDGKFYQL
Mflv_1117|M.gilvum_PYR-GCK WNEEESGAYGIELGSITERFDRFEEACQVLRGLLSQ--ETTTSDGRFYQL
Mvan_5695|M.vanbaalenii_PYR-1 WNEEESGAYGIELGSIKERFDRFEEACQVLKGLLSQ--DTTTFDGKFYQL
MAB_4496c|M.abscessus_ATCC_199 WNEEESGAYGIELGSIKERFDRFEEACEVLTGLLSR--ETTNFDGKFYQL
MSMEG_6454|M.smegmatis_MC2_155 WNEEESGAYGIELGSIKERFDRFEEACEVLKGLLTQ--ETTTFDGKFYQL
TH_4285|M.thermoresistible__bu WNEEESGAYGIELGTLKERFDRFEEACQVLISLLSQ--ETTDFDGAYYRL
MLBr_00131|M.leprae_Br4923 E-REGNEPYGVEWT---KPVARFQEALATIRALWDSNGELVSRESQFFPL
.. . .**: . . : *: .: .: . :: *
Mb0815c|M.bovis_AF2122/97 DGATCDPPPVQRPHPPLWIGGEGD-RVQRIAAKHAQGLN-VRWWSPQQVT
Rv0791c|M.tuberculosis_H37Rv DGATCDPPPVQRPHPPLWIGGEGD-RVQRIAAKHAQGLN-VRWWSPQQVT
MMAR_5411|M.marinum_M EDARNEPKGPQRPHPPICIGGSGEKRTLRITARYAQHWN-FAGGTPEEFA
MUL_5034|M.ulcerans_Agy99 EDARNEPKGPQRPHSPICIGGSGEKRTLRITARYAQHWN-FAGGTPEEFA
MAV_0169|M.avium_104 KGARNEPKGPQRPHPPICIGGSGEKRTLRITARYAQHWN-FVGGPPDVFA
Mflv_1117|M.gilvum_PYR-GCK KDARNEPKGPQQPHPPICIGGNGEKRTLRITAQYADHWN-YVGGTPEEFA
Mvan_5695|M.vanbaalenii_PYR-1 KDARNEPKGPQRPHPPICIGGSGEKRTLRITAQYADHWN-FVGGPPEEFA
MAB_4496c|M.abscessus_ATCC_199 KDARNEPKGPQKPHPPICIGGSGEKRTLRITARYAQHWN-FVGGPPEEFA
MSMEG_6454|M.smegmatis_MC2_155 KDARNEPKGPQQPHPPFCIGGSGEKRTLRITAKYADHWN-FVGGTPEEFA
TH_4285|M.thermoresistible__bu KSARNEPKGPQQPHPPICIGGSGEKRTLRITAKYADHWN-FVGGPPEEFA
MLBr_00131|M.leprae_Br4923 HNALFDLPPYRGKWPEIWVAAHGP-RMLQATGRYADAWIPIVLVRPTDYS
..* : : . : :.. * * : :.::*: * :
Mb0815c|M.bovis_AF2122/97 QRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEP
Rv0791c|M.tuberculosis_H37Rv QRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEP
MMAR_5411|M.marinum_M RKRDVLAAHCADIGRDPKEITLSAHLGLAPERD-----------------
MUL_5034|M.ulcerans_Agy99 RKRDVLAAHCADIGRDPKEITLSAHRGLAPERD-----------------
MAV_0169|M.avium_104 HKRDVLASHCADIGRDPKEILLSAHLRLEPDLD-----------------
Mflv_1117|M.gilvum_PYR-GCK RKRDVLAAHCADIGRDPKEIMLSAHVRLGADLD-----------------
Mvan_5695|M.vanbaalenii_PYR-1 RKRDVLARHCADIGRDPGEISLSAHIRLGADLD-----------------
MAB_4496c|M.abscessus_ATCC_199 RKREVLAAHCADIGRDPKEITLSAHIRLGADRD-----------------
MSMEG_6454|M.smegmatis_MC2_155 RKRDVLAAHCADLGRDPKEITLSAHVRLGEDRD-----------------
TH_4285|M.thermoresistible__bu RKRDVLAAHCADVGRDPREIRLSAHVRLGEDGD-----------------
MLBr_00131|M.leprae_Br4923 CALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVDEALDSVLVRMIA
.: . **** : :. :
Mb0815c|M.bovis_AF2122/97 G-------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv G-------------------------------------------------
MMAR_5411|M.marinum_M --------------------------------------------------
MUL_5034|M.ulcerans_Agy99 --------------------------------------------------
MAV_0169|M.avium_104 --------------------------------------------------
Mflv_1117|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5695|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4496c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6454|M.smegmatis_MC2_155 --------------------------------------------------
TH_4285|M.thermoresistible__bu --------------------------------------------------
MLBr_00131|M.leprae_Br4923 LGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKVPAALMK
Mb0815c|M.bovis_AF2122/97 --LIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRV
Rv0791c|M.tuberculosis_H37Rv --LIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRV
MMAR_5411|M.marinum_M -------FGQVIENAAALAAEGLDLGIVYIAPPHDPAVLEPMAEAIRESG
MUL_5034|M.ulcerans_Agy99 -------FGQVIENAAALAAEGLDLGIVYIAPPHDPAVLEPMAEAIRESG
MAV_0169|M.avium_104 -------YGKVIDDAAALAAEGLDLGIVYLPPPHDPAVLEPLAEAIRDSG
Mflv_1117|M.gilvum_PYR-GCK -------VDKVIAEAAALGDEGLDLAIVYLPPPYDPAVLEPLAEKIRASG
Mvan_5695|M.vanbaalenii_PYR-1 -------YDKVIEEAAALGAEGLELAIVYLPLPHDPAVLEPLADKIRASG
MAB_4496c|M.abscessus_ATCC_199 -------YARVVDEAASLGAEGLDLAIIYLPPPYDPAVLEPLAQALRG--
MSMEG_6454|M.smegmatis_MC2_155 -------YAKVIDEAAALGAEGLDLAIIYLPPPYDPAVLEPLAQAIRDSG
TH_4285|M.thermoresistible__bu -------CRKVVDEAAALASEGLDLAIVYLPTPHTPAVLEPLAEAIRDSG
MLBr_00131|M.leprae_Br4923 EVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHAR
. : .*: :. . . :. :
Mb0815c|M.bovis_AF2122/97 KTEVTIP-
Rv0791c|M.tuberculosis_H37Rv KTEVTIP-
MMAR_5411|M.marinum_M LIDG----
MUL_5034|M.ulcerans_Agy99 LIDG----
MAV_0169|M.avium_104 LLRS----
Mflv_1117|M.gilvum_PYR-GCK LLDSNVDG
Mvan_5695|M.vanbaalenii_PYR-1 LLDSKAR-
MAB_4496c|M.abscessus_ATCC_199 --------
MSMEG_6454|M.smegmatis_MC2_155 QLTAA---
TH_4285|M.thermoresistible__bu LPAR----
MLBr_00131|M.leprae_Br4923 VLRGLKKL