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RFGIFVPQGWRLDLVGIAPRDQWQVMRDLASYVDEGGVWDSLWVYDHFHTVPVPTAEATHEAWSLMSAYA ATTSRIKLGQMCTAMSYRNPVYLAKVAATADIISGGRIQMGIGGGWYEHEWRAYGYGFPSAGVRLARLDE GVQIMRDAWRDGTVTFDGKHYQADGAIVAPRPLQQAGIPLWIAGGGEKVTLRIAAKYAQYTNFTSEPEGF AHKSQVLAEHCRDVGTDFDKIVRSANINAVVGSSESDVKDRLARVRSRISALTGEPAADAMLNSMSSPEA GSGTPEQLIDTLRRLRELGCEYVICYFPEAAYDRSGIELFEREVIPALS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5062 | - | - | 100% (330) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5695 | - | 9e-41 | 39.81% (216) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_2247 | - | 3e-35 | 33.79% (290) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 7e-34 | 30.36% (303) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_1696 | - | 1e-175 | 86.36% (330) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 8e-34 | 30.36% (303) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00269 | - | 7e-18 | 27.07% (351) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0858 | - | 1e-136 | 70.25% (326) | luciferase-like monooxygenase |
| M. marinum M | MMAR_4673 | - | 1e-157 | 78.48% (330) | hypothetical protein MMAR_4673 |
| M. avium 104 | MAV_0986 | - | 1e-158 | 79.09% (330) | hypothetical protein MAV_0986 |
| M. smegmatis MC2 155 | MSMEG_5715 | - | 1e-161 | 80.00% (330) | hypothetical protein MSMEG_5715 |
| M. thermoresistible (build 8) | TH_4607 | - | 1e-149 | 73.64% (330) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0292 | - | 1e-150 | 78.93% (318) | hypothetical protein MUL_0292 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 ---------MNAKDDPHFGLMLAA----TVNGLAVG-SYREMVVVSQTAE
Rv0791c|M.tuberculosis_H37Rv ---------MNAKDDPHFGLMLAA----TVNGLAVG-SYREMVVVSQTAE
Mvan_5062|M.vanbaalenii_PYR-1 ---------------MRFGIFVPQGWRLDLVGIAPRDQWQVMRDLASYVD
Mflv_1696|M.gilvum_PYR-GCK ---------------MRFGLFIPQGWRLDLVGIDPREQWRVMSDLATYVD
MMAR_4673|M.marinum_M ---------------MRFGLFIPQGWRMDLVGIAPEQHWAVMRDLATYAD
MUL_0292|M.ulcerans_Agy99 ---------------------------MDLVGIAPEQHWAVMRDLATYAD
MAV_0986|M.avium_104 MKTVAVRPVRLESRGMRFGLFIPQGWRMDLVGIEPDEHWAVMRDLAQRAD
MSMEG_5715|M.smegmatis_MC2_155 ---------------MRFGLFIPQGWRLDLVDIPTDRHWSVMRDLAAYAD
TH_4607|M.thermoresistible__bu ---------------MRFGLFIPQGWRLDLVDIPPERHWQVMRDLAVYAD
MAB_0858|M.abscessus_ATCC_1997 --------MAQVAETLEFGVFIPQGWRLDLVGIAPERHWDVMRDLVHYAE
MLBr_00269|M.leprae_Br4923 ----------------------MAELRLGYKASAEQFAPRELVELGVAAE
: : .:
Mb0815c|M.bovis_AF2122/97 EYG-FDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
Rv0791c|M.tuberculosis_H37Rv EYG-FDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
Mvan_5062|M.vanbaalenii_PYR-1 EGGVWDSLWVYDHFHTVP-----------VPTAEAT--------------
Mflv_1696|M.gilvum_PYR-GCK AGDAWDSLWVYDHFHTVP-----------VPTDEAT--------------
MMAR_4673|M.marinum_M ASA-WDSLWVYDHFHTVP-----------LPSDEAT--------------
MUL_0292|M.ulcerans_Agy99 ASA-WDSLWVYDHFHTVP-----------LPSDEAT--------------
MAV_0986|M.avium_104 RDVGWDSLWVYDHFHTVP-----------VPTGEAT--------------
MSMEG_5715|M.smegmatis_MC2_155 GSQAWDSLWVYDHFHTVP-----------VPTGEAT--------------
TH_4607|M.thermoresistible__bu QS-AWDSIWVYDHFHTVP-----------MPTHEAT--------------
MAB_0858|M.abscessus_ATCC_1997 GGP-WDSVWVYDHFHTVP-----------VPTDEAT--------------
MLBr_00269|M.leprae_Br4923 AHG-MDSATVSDHFQPWR-----------HQGGHAS--------------
** : *** . *:
Mb0815c|M.bovis_AF2122/97 SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVIS
Rv0791c|M.tuberculosis_H37Rv SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVIS
Mvan_5062|M.vanbaalenii_PYR-1 ----HEAWSLMSAYAATTSRIKLGQMCTAMSYRN-PVYLAKVAATADIIS
Mflv_1696|M.gilvum_PYR-GCK ----HEAWSLMSAYAATTSRVKLGQMCTAMSYRN-PAYLAKVAATADVIS
MMAR_4673|M.marinum_M ----HEAWSLMAAYAAVTSRIKLGQMCTAMSYRN-PVYLAKVAATTDIIS
MUL_0292|M.ulcerans_Agy99 ----HEAWSLMAAYAAVTSRIKLGQMCTAMSYRN-PVYLAKVAATADIIS
MAV_0986|M.avium_104 ----HEAWSLMAAYAAVTSRIKLGQMCTAMSYRN-PVYLAKVAATADIIS
MSMEG_5715|M.smegmatis_MC2_155 ----HEAWTLMAAYAATTSRIKLGQMCTAMSYRN-PVYLAKVAATTDVIS
TH_4607|M.thermoresistible__bu ----HEAWSLMAAYAASTRSIKLGQMCTAMSFRN-PVYLAKVAATVDVIS
MAB_0858|M.abscessus_ATCC_1997 ----HEAWTLMSAFAAVTSRIKLGQMCTAMGYRN-PVYLAKIAATVDIIS
MLBr_00269|M.leprae_Br4923 -----FSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLY
. : ::* . * : ** :* * :.: ** . :
Mb0815c|M.bovis_AF2122/97 QGRLDLGLGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPN
Rv0791c|M.tuberculosis_H37Rv QGRLDLGLGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPN
Mvan_5062|M.vanbaalenii_PYR-1 GGRIQMGIGGGWYEHEWR-AYGYGFPSAGVRLARLDEGVQIMRDAWRDGT
Mflv_1696|M.gilvum_PYR-GCK GGRIQMGIGGGWYEHEWR-AYGYGFPSAGTRLARLDEGVQIMRDAWRDGV
MMAR_4673|M.marinum_M GGRIQMGIGGGWYEHEWR-AYGYGFPSAGTRLGRLDEGVQIMRDAWRDGK
MUL_0292|M.ulcerans_Agy99 GGRIQMGIGGGWYEHEWR-AYGYGFPSAGVRLGRLDEGVQIMRDAWRDGK
MAV_0986|M.avium_104 GGRIQMGIGAGWYEHEWR-AYGYGFPSAGVRLGRLDEGVQIMRDAWRDGK
MSMEG_5715|M.smegmatis_MC2_155 GGRVQMGIGGGWYEHEWR-AYGYGFPSAGERLGRLDEGVQIMRDAWRDGR
TH_4607|M.thermoresistible__bu GGRVQMGIGAGWYEHEWR-AYGYGFPPAKVRLGRLDEGVQIMHDAWLNGI
MAB_0858|M.abscessus_ATCC_1997 GGRAQMGIGGGWYEHEWR-AYGYGFPGAAERLGRLREGVRIMRDAWRDGR
MLBr_00269|M.leprae_Br4923 PNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDR
.* :*:* * .* .* :* *.. * *.::::: *
Mb0815c|M.bovis_AF2122/97 PTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQR-IAAKHAQGLNV
Rv0791c|M.tuberculosis_H37Rv PTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQR-IAAKHAQGLNV
Mvan_5062|M.vanbaalenii_PYR-1 VTFDGKHYQADGAIVAPRPLQQAGIPLWIAGGGEKVTLRIAAKYAQYTNF
Mflv_1696|M.gilvum_PYR-GCK VSFDGKHYQVDGAIVAPRPLQDGGLPLWIAGGGEKVTLRIAAKYAQYTNF
MMAR_4673|M.marinum_M VSFDGKHYQVDGAIVAPKPLQNNGIPLWVAGGGEKVTLRIAAQYAQYTNF
MUL_0292|M.ulcerans_Agy99 VSFDGKHYQVDGAIVAPKPLQNNGIPLWVAGGGEKVTLRIAAQYAQYTNF
MAV_0986|M.avium_104 VSFNGRHYQVDGAIVAPKPLQDNGIPLWIAGGGEKVTLRIAAEYAQYTNF
MSMEG_5715|M.smegmatis_MC2_155 VSFDGKHYQADGAIVSPTPLQEDGIPLWIAGGGEKVTLKIAAKYAQYTNF
TH_4607|M.thermoresistible__bu VSFDGEHYQVDGAIVEPRPLQDERIPLWIAGGGEKVTLRIAAKYADYTNY
MAB_0858|M.abscessus_ATCC_1997 VSLDGTYYQVDDAIVAPTPLQSNGIPLWIAGGGEKVTLRIAARYAQYTNF
MLBr_00269|M.leprae_Br4923 VDFDGDYYQLKGASIYDVPE--GGVPIYIAAGGPEVAKYAGRAGEGFVCT
* .* ..* * *:::.. * .* .
Mb0815c|M.bovis_AF2122/97 RWWSPQQVTQRRG-FLTQASEAAGRDPDTLR--LSVTLLLAPTQSGEEE-
Rv0791c|M.tuberculosis_H37Rv RWWSPQQVTQRRG-FLTQASEAAGRDPDTLR--LSVTLLLAPTQSGEEE-
Mvan_5062|M.vanbaalenii_PYR-1 TSE-PEGFAHKSQ-VLAEHCRDVGTDFDKIVRSANINAVVGSSESDVKDR
Mflv_1696|M.gilvum_PYR-GCK TSE-PDGFEHKSR-VLAEHCKDVGTDFDAIVRSANINVVVGTSEADVEDR
MMAR_4673|M.marinum_M TPQ-PEQFAHKSQ-VLAEHCRKLGTEFDAIVRSANFTAVLGTSEADVKDR
MUL_0292|M.ulcerans_Agy99 TPQ-PEQFAHKSQ-VLAEHCRKLGTEFDAIVRSANFTAVLGTAEADVKDR
MAV_0986|M.avium_104 TPE-SAAFAHKSE-VLAAHCRDVGTDFDAIVRSVNVNAVVGASRADVDDR
MSMEG_5715|M.smegmatis_MC2_155 TSE-PEAFRRKSQ-ILAEHCRTVGTDFDAIVRSANFNAVIGESEKDVKER
TH_4607|M.thermoresistible__bu TCD-PEGFERKSE-ILAEHCHDVGTDFEAIVRSANFNAVLGETESEVADR
MAB_0858|M.abscessus_ATCC_1997 GQT-AEEFGHKSR-VLAAHCKDIGTDFDAIVRSANMNIVIGSDAGEVADR
MLBr_00269|M.leprae_Br4923 SGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSN
.: : . * : : : ... .
Mb0815c|M.bovis_AF2122/97 --------------VRIR-----------EEFASIPEPGLIVGTPDRCVE
Rv0791c|M.tuberculosis_H37Rv --------------VRIR-----------EEFASIPEPGLIVGTPDRCVE
Mvan_5062|M.vanbaalenii_PYR-1 L-----------ARVRSRISALTGEPAADAMLNSMSSPEAGSGTPEQLID
Mflv_1696|M.gilvum_PYR-GCK L-----------ARVRSRISDLTGEAAADAMLNAMNSPQAGSGTPEQLVE
MMAR_4673|M.marinum_M M-----------GRVRDRLVGYVPEAVADSMVGGLP--DSATGTPEQVIE
MUL_0292|M.ulcerans_Agy99 L-----------GRVRDRLVGYVPEAVADSMVGGLP--DSATGTPEQVIE
MAV_0986|M.avium_104 L-----------RRIRDRMAGYVGESAADAMIAGTSGVDSATGTTEQVIE
MSMEG_5715|M.smegmatis_MC2_155 I-----------ERLRARQSPVAGEDAVDAMLSTMSAPESASGTPEQVIE
TH_4607|M.thermoresistible__bu L-----------QQVRARLVSRVGEDAADGMVDSIKAPSSATGTPDQVIE
MAB_0858|M.abscessus_ATCC_1997 L-----------AAIKARLVPIIGEDVAEGTVANLA---TTAGTPEQIAE
MLBr_00269|M.leprae_Br4923 IRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVA
. . .:.
Mb0815c|M.bovis_AF2122/97 RIREYQDRGVGHFLFTIPHVVKS-DYLHIIGSDIIPRVKTEVTIP
Rv0791c|M.tuberculosis_H37Rv RIREYQDRGVGHFLFTIPHVVKS-DYLHIIGSDIIPRVKTEVTIP
Mvan_5062|M.vanbaalenii_PYR-1 TLRRLRELGCEYVICYFPEAAYDRSGIELFEREVIPALS------
Mflv_1696|M.gilvum_PYR-GCK SLQRLRDLGCEYVICYFPEAAYDRSSIEMFEREIMPALA------
MMAR_4673|M.marinum_M RLAQIRDLGCEYAICYFPEAAYDRSGIELFEREVIPALS------
MUL_0292|M.ulcerans_Agy99 RLAQIRDLGCEYAICYFPEAAYDRSGIELFEREVIPALS------
MAV_0986|M.avium_104 RLARLRDLGCDYVICYFPEAAYDRSGIELFEREIIPALS------
MSMEG_5715|M.smegmatis_MC2_155 KLKRVRDLGCEYAILYFPEAAYDRSGIELFEQKVIPALS------
TH_4607|M.thermoresistible__bu RLQRMRDLGCEYAIMYFPEAAYDRSGIEMFEQKVIPALS------
MAB_0858|M.abscessus_ATCC_1997 RLAEYRGLGLGYAICNFPEAAYDRSGIDLFVREVIGV--------
MLBr_00269|M.leprae_Br4923 RVGQYVTWGLNHLVFHAPG-HNQRRFLELFEKDLAPRLRRLG---
: . * : : * . :.:: .: