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LDLPGVRSSRMESPRESPDVPMISMKAVNKHFGSLHVLKDINLDVGQGQVVVVLGPSGSGKSTLCRTINR LETIDSGTIAIDGKVLPAEGRGLAQLRSDVGMVFQSFNLFAHKTILENVTLAPMKVRKTSKDQAREKAMS LLERVGVANQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEVLAVMAGLATDGMTM LVVTHEMGFARRAANRVVFMSDGAIVEDAEPARFFEHPQTDRAKDFLGKILHH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2428 | - | - | 100% (264) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2834 | - | 3e-72 | 55.78% (251) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4704 | - | 4e-70 | 55.65% (239) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 2e-37 | 37.45% (235) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3968 | - | 1e-125 | 92.21% (244) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 2e-37 | 37.45% (235) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00669 | ftsE | 2e-35 | 37.73% (220) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3050 | - | 1e-108 | 76.11% (247) | putative glutamate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 3e-64 | 51.05% (239) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 1e-64 | 51.46% (239) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_2728 | - | 1e-122 | 84.29% (261) | glutamate transport ATP-binding protein GluA |
| M. thermoresistible (build 8) | TH_1784 | - | 1e-118 | 86.07% (244) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 5e-38 | 37.87% (235) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2428|M.vanbaalenii_PYR-1 MLDLPGVRSSRMESPRESPDVPMISMKAVNKHFGSLH--VLKDINLDVGQ
Mflv_3968|M.gilvum_PYR-GCK --------------------MPMISMKSVNKHFGPLH--VLKDIDLEVGR
MSMEG_2728|M.smegmatis_MC2_155 -MGSPGEQP-QVDGAAQS-DVPMISLQGVNKHFGQLH--VLKDINLDVGK
TH_1784|M.thermoresistible__bu -MDSAGADVAVADPAAEA--VPMISMRGVNKYFGSLH--VLRDINLDVAR
MAB_3050|M.abscessus_ATCC_1997 --MPVSTDTSTSGESSSAPSVPMIALEHVNKHFGDLH--VLKDITLEIPR
MMAR_0060|M.marinum_M -----------MTRQDAGRQPVCLAARSIHQTLGGSV--VLRGVDLEVPA
MAV_0058|M.avium_104 -----------MS-NPASRASVSLACKDIHQTLNGNA--VLRGVDLDTPA
MLBr_00669|M.leprae_Br4923 ----------------------MITLDHVSKKYKSLARPALDNVNVKIDK
Mb2419c|M.bovis_AF2122/97 -------------MT------YAIVVADATKRYGDFV--ALDHVDFVVPT
Rv2397c|M.tuberculosis_H37Rv -------------MT------YAIVVADATKRYGDFV--ALDHVDFVVPT
MUL_3658|M.ulcerans_Agy99 -------------MTGPGTGGHAIVVRDAFKQYGDFV--ALDHVDFVVPA
: : .* : .
Mvan_2428|M.vanbaalenii_PYR-1 GQVVVVLGPSGSGKSTLCRTINRLETIDSGTIAIDGKVLPA-EGRGLAQL
Mflv_3968|M.gilvum_PYR-GCK GQVVVVLGPSGSGKSTLCRTINRLETIDSGTIAIDGVELPA-EGRKLAQL
MSMEG_2728|M.smegmatis_MC2_155 GQVVVVLGPSGSGKSTLCRTINRLETIDSGTIMVDGKVLPA-EGRRLAQL
TH_1784|M.thermoresistible__bu GQVVVVLGPSGSGKSTLCRTLNRLEPIDSGAISIDGVALPA-EGRELARL
MAB_3050|M.abscessus_ATCC_1997 GQVVVILGPSGSGKSTLCRTINRLEPIDGGTIRIDGAILPE-EGRALASL
MMAR_0060|M.marinum_M GTTAAVIGPSGSGKSTLLRTLNRLHEPDSGDILLDGRSVLR-DNP--NDL
MAV_0058|M.avium_104 GSTVAVIGPSGSGKSTLLRTLNRLYEPDRGDILLDGRSVLH-DDP--DQL
MLBr_00669|M.leprae_Br4923 GEFVFLIGPSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLPGRHIPRL
Mb2419c|M.bovis_AF2122/97 GSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR-----VPPQ
Rv2397c|M.tuberculosis_H37Rv GSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR-----VPPQ
MUL_3658|M.ulcerans_Agy99 GSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTR-----VPPQ
* . ::*********: * : * : :. :
Mvan_2428|M.vanbaalenii_PYR-1 RSDVGMVFQSFNLFAHKTILENVTLAPMKVRKTSKDQAREKAMSLLERVG
Mflv_3968|M.gilvum_PYR-GCK RSDVGMVFQSFNLFAHKTILENVTLAPMKVRKFSKDESREKAMALLERVG
MSMEG_2728|M.smegmatis_MC2_155 RSDVGMVFQSFNLFAHKTILENVTLAPMKVRRFAKDKARENALALLERVG
TH_1784|M.thermoresistible__bu RADVGMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERVG
MAB_3050|M.abscessus_ATCC_1997 RAEVGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLERVG
MMAR_0060|M.marinum_M RQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVG
MAV_0058|M.avium_104 RQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVG
MLBr_00669|M.leprae_Br4923 RQVIGCVFQDFRLLQQKTVYENVAFALEVIGRRS-DAINQVVPDVLETVG
Mb2419c|M.bovis_AF2122/97 RRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVVG
Rv2397c|M.tuberculosis_H37Rv RRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVVG
MUL_3658|M.ulcerans_Agy99 RRGIGFVFQHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNLLEVVG
* :* *** : : : .: :**: . : . . *: **
Mvan_2428|M.vanbaalenii_PYR-1 VANQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEV
Mflv_3968|M.gilvum_PYR-GCK VANQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEV
MSMEG_2728|M.smegmatis_MC2_155 VANQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEV
TH_1784|M.thermoresistible__bu VADQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEV
MAB_3050|M.abscessus_ATCC_1997 IASQKDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDPEMVNEV
MMAR_0060|M.marinum_M LKHKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGI
MAV_0058|M.avium_104 LKHKAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGI
MLBr_00669|M.leprae_Br4923 LSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDI
Mb2419c|M.bovis_AF2122/97 LSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREEL
Rv2397c|M.tuberculosis_H37Rv LSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREEL
MUL_3658|M.ulcerans_Agy99 LSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDL
: . * ****::**:*:**::. * *:: **. . **.. : :
Mvan_2428|M.vanbaalenii_PYR-1 LAVMAGLATDG-MTMLVVTHEMGFARRAANRVVFMSDGAIVEDAEPARFF
Mflv_3968|M.gilvum_PYR-GCK LAVMTGLAGDG-MTMLVVTHEMGFARRAANRVVFMSDGAVVEDAEPIQFF
MSMEG_2728|M.smegmatis_MC2_155 LAVMSSLASEG-MTMVVVTHEMGFARRASDRVVFMSDGAIVEDSSPAEFF
TH_1784|M.thermoresistible__bu LAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSDGAIVEDAEPARFF
MAB_3050|M.abscessus_ATCC_1997 LDVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADGAIVEDSDPESFF
MMAR_0060|M.marinum_M LALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGPPEQLF
MAV_0058|M.avium_104 LQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGPPEQIF
MLBr_00669|M.leprae_Br4923 MDLLERINRTG-TTVLMATHDHHIVDSMRQRVVELSLGRLVRD----EWC
Mb2419c|M.bovis_AF2122/97 RAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVY
Rv2397c|M.tuberculosis_H37Rv RAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVY
MUL_3658|M.ulcerans_Agy99 RAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVY
: : * ::.**: . : : : * : .
Mvan_2428|M.vanbaalenii_PYR-1 EHPQTDRAKDFLGKILHH--------------------------------
Mflv_3968|M.gilvum_PYR-GCK DNPQTDRAKDFLGKILHH--------------------------------
MSMEG_2728|M.smegmatis_MC2_155 DNPKSERAKDFLGKILHH--------------------------------
TH_1784|M.thermoresistible__bu EDPQTDRARDFLGKILHH--------------------------------
MAB_3050|M.abscessus_ATCC_1997 TNPKSERAKDFLGKILGH--------------------------------
MMAR_0060|M.marinum_M EAARTERLQRFLAQVL----------------------------------
MAV_0058|M.avium_104 EAAETERLQRFLSQVL----------------------------------
MLBr_00669|M.leprae_Br4923 GIYGMDR-------------------------------------------
Mb2419c|M.bovis_AF2122/97 DAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGV
Rv2397c|M.tuberculosis_H37Rv DAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGV
MUL_3658|M.ulcerans_Agy99 DAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGV
Mvan_2428|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3968|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2728|M.smegmatis_MC2_155 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MLBr_00669|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 LRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYV
Rv2397c|M.tuberculosis_H37Rv LRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYV
MUL_3658|M.ulcerans_Agy99 TRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYV
Mvan_2428|M.vanbaalenii_PYR-1 ----------------------------------
Mflv_3968|M.gilvum_PYR-GCK ----------------------------------
MSMEG_2728|M.smegmatis_MC2_155 ----------------------------------
TH_1784|M.thermoresistible__bu ----------------------------------
MAB_3050|M.abscessus_ATCC_1997 ----------------------------------
MMAR_0060|M.marinum_M ----------------------------------
MAV_0058|M.avium_104 ----------------------------------
MLBr_00669|M.leprae_Br4923 ----------------------------------
Mb2419c|M.bovis_AF2122/97 RATRVPPIAGGVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv RATRVPPIAGGVSGVDDAGVERVKVTST------
MUL_3658|M.ulcerans_Agy99 RATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ