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SRRDVVYLVSRFPVTSETFIVREIEALDRSGKFHVEIRSLFPSPDEPVHDIARRWSRHLVRPTARDAATG LAWALLTRPIAVMSVLATVTSGYLRRPPLLVRALTTVPIACAHARDLARRGRPCHVHAHYATYPALAAWV CRRLAGISYSFTVHAHDLYVDMSMLDRKIADACYVVTISQYNRALLEQHNSMGTPIRVVHAGIDVGAYRF RARGVPAEGEVRALTVASLQQYKGHAVLLEALAMGGPEVDRITLDLIGDGVLRGDLEALVDRLGLRDRVR FLGSCSEEAVRAALDAADLFVLPSIVADDGQMEGLPVALMEALACGVPAVSTKLSGIPEIVVDGVTGLLA TPGDAASLNATLTAMVQRGTAAVEFADAGRALVSREFDLRESIAALTGLLDEYLPPVAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5245 | - | - | 100% (410) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_5246 | - | 3e-17 | 31.84% (267) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_3550 | - | 1e-14 | 28.68% (265) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 1e-14 | 27.37% (285) | transferase |
| M. gilvum PYR-GCK | Mflv_1501 | - | 0.0 | 80.30% (406) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv3032 | - | 1e-14 | 27.37% (285) | transferase |
| M. leprae Br4923 | MLBr_00886 | - | 1e-16 | 29.03% (279) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_1976 | - | 4e-16 | 27.17% (254) | hypothetical protein MAB_1976 |
| M. marinum M | MMAR_4514 | - | 3e-14 | 29.15% (295) | glycosyl transferase |
| M. avium 104 | MAV_4082 | - | 1e-17 | 31.65% (218) | transferase |
| M. smegmatis MC2 155 | MSMEG_0933 | - | 1e-16 | 31.78% (214) | hypothetical protein MSMEG_0933 |
| M. thermoresistible (build 8) | TH_2191 | - | 5e-17 | 33.66% (202) | POSSIBLE TRANSFERASE |
| M. ulcerans Agy99 | MUL_1919 | - | 4e-14 | 29.84% (191) | transferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4082|M.avium_104 ----------MRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALAR-RG
MSMEG_0933|M.smegmatis_MC2_155 MRLATDLETPRRVAVLSVHTSPLAQPGTGDAGGMNVYVLQTALQLAR-RG
Mb3058|M.bovis_AF2122/97 ----------MRILMVSWEYPPVVIG------GLGRHVHHLSTALAA-AG
Rv3032|M.tuberculosis_H37Rv ----------MRILMVSWEYPPVVIG------GLGRHVHHLSTALAA-AG
MUL_1919|M.ulcerans_Agy99 ----------MKILMVSWEYPPVVIG------GLGRHVHHLATALVA-AG
TH_2191|M.thermoresistible__bu ----------MKILMVSWEYPPVVVG------GLGRHVYHLSTALAA-AG
MLBr_00886|M.leprae_Br4923 ---------MSRVLLVTNDFPPRRGG-------IQSYLGEFVDRLINIGS
MAB_1976|M.abscessus_ATCC_1997 -MTFHPGGLRQRILLVTNDFPPRPGG-------IQSYLQEMVSRLA--GS
Mvan_5245|M.vanbaalenii_PYR-1 MSRRDVVYLVSRFPVTSETFIVREIEALD---RSGKFHVEIRSLFPS-PD
Mflv_1501|M.gilvum_PYR-GCK MNRRHVTYLVSRFPVTSETFIVRELEALD---RSGEFELEIRSLFPS-PD
MMAR_4514|M.marinum_M --------------MNSVGVPTPQDR-------LRVLVVGPAPAAATSRG
: : .
MAV_4082|M.avium_104 HDVVVYTRR----DDPRLPDSVETPHGYSVVHVPAGPARVLPKDELLQYM
MSMEG_0933|M.smegmatis_MC2_155 VEVEVFTRA----TSSADAPVVPVAPGVLVRNVVAGPFEGLDKNDLPTQL
Mb3058|M.bovis_AF2122/97 HDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWT
Rv3032|M.tuberculosis_H37Rv HDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWT
MUL_1919|M.ulcerans_Agy99 HEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEFSFGSDMMAWT
TH_2191|M.thermoresistible__bu HEVVVLSRRPTGTDPSTHPSTDEVRDGVRVLAAAQDPHEFDFGRDMMAWT
MLBr_00886|M.leprae_Br4923 HDVMVYAPQ---------------WTGADTFDNAAHDGGYQVVRHPGTLM
MAB_1976|M.abscessus_ATCC_1997 HEVTVYAPR---------------WKGCERYDAAAE---YQVVRHPTSLM
Mvan_5245|M.vanbaalenii_PYR-1 EPVHDIARRWS--RHLVRPTARDAATGLAWALLTRPIAVMSVLATVTSGY
Mflv_1501|M.gilvum_PYR-GCK RAVHEIARRWN--EHLVRPSAFDAAAGVTWALLTRPIALMTILANVVAGY
MMAR_4514|M.marinum_M GMATVIALM---------AAHPDPHIHITAVPTFIDGPLWPRLMLGVRGM
. :
MAV_4082|M.avium_104 YGFAQFLRQQWCSDGP-----------DVAHAHFWMSGVATQQAARAHSI
MSMEG_0933|M.smegmatis_MC2_155 CAFTAGVLRAEATHEPGY--------YDVVHSHYWLSGQVGWLARDRWAV
Mb3058|M.bovis_AF2122/97 LAMGHAMIRAGLRLKKLG--TDRSWRPDVVHAHDWLVAHPAIALAQFYDV
Rv3032|M.tuberculosis_H37Rv LAMGHAMIRAGLRLKKLG--TDRSWRPDVVHAHDWLVAHPAIALAQFYDV
MUL_1919|M.ulcerans_Agy99 LAMGHAMVRAGLTLSGPG--AEQPWQPDIVHAHDWLVAHPAIALADYYDV
TH_2191|M.thermoresistible__bu LAMGHSMVRAGLALGLRGGTGGTPWQPDVVHAHDWLVAHPAIALAEFFDV
MLBr_00886|M.leprae_Br4923 LPGPAVDARMRRLIVDHG-----------IDTVWFGSAAPLALLAPCARK
MAB_1976|M.abscessus_ATCC_1997 LPGPGVRRRMVDLIRAQH-----------ADVVWFGAAAPLALLSSAAKA
Mvan_5245|M.vanbaalenii_PYR-1 LRRPPLLVRALTTVPIAC----------AHARDLARRGRPCHVHAHYATY
Mflv_1501|M.gilvum_PYR-GCK RRRLPLLVRALMTVPLAC----------AHARDLARRAQPCHVHAHYATY
MMAR_4514|M.marinum_M LRATWLVLRKRADVLHVH----------LAHGGSVIRKALPLLAARLTGT
:
MAV_4082|M.avium_104 PTVQTFHALGLTKRLHQGS-DDTSPDCRIDVEARVAREADWVAATSTDEV
MSMEG_0933|M.smegmatis_MC2_155 PLVHTAHTLAAVKNAALAAGDAPEPPLRAVGEQQVVDEADRLIVNTEVEA
Mb3058|M.bovis_AF2122/97 PMVSTIHATEAGRHSGWVSGALSR--QVHAVESWLVRESDSLITCSASMN
Rv3032|M.tuberculosis_H37Rv PMVSTIHATEAGRHSGWVSGALSR--QVHAVESWLVRESDSLITCSASMN
MUL_1919|M.ulcerans_Agy99 PMVSTIHATEAGRHSGWVSGDLSR--QVHAVESWLVRESDSLITCSGSMS
TH_2191|M.thermoresistible__bu PLVSTIHATEAGRHSGWVSGPISR--QVHAVESWLVRDSDSLITCSASMS
MLBr_00886|M.leprae_Br4923 AGATRVLASTHGHEVGWSMLPVAR-----SVLRRIGDVTDVVTFVSRYTR
MAB_1976|M.abscessus_ATCC_1997 AGAAVTAASTHGHEVGWSMLPVAR-----SALRQIGESTDVITYVSRYTR
Mvan_5245|M.vanbaalenii_PYR-1 PALAAWVCRRLAGISYSFTVHAHDLYVDMSMLDRKIADACYVVTISQYN-
Mflv_1501|M.gilvum_PYR-GCK PALAAWVCHRLAGTSYSFTVHAHDLYVDTSMLDRKIAEARYVVTISHYN-
MMAR_4514|M.marinum_M PAIVHAHSYDFGGWFDQLAPPARA-------AVRRMLAADHWVVLGERHV
. :
MAV_4082|M.avium_104 FELVRMGRA-RSRTSVVPCGVDLDAFTPD-GPVAARGAR-----PRIVT-
MSMEG_0933|M.smegmatis_MC2_155 QQLVSLHNADRSRIDVVHPGVDLDVFTPG-SRDAARAVFGLPTDQKIVAF
Mb3058|M.bovis_AF2122/97 DEITELFGPGLAEITVIRNGIDAARWPFA-ARRPRTGPA-------ELLY
Rv3032|M.tuberculosis_H37Rv DEITELFGPGLAEITVIRNGIDAARWPFA-ARRPRTGPA-------ELLY
MUL_1919|M.ulcerans_Agy99 DEITELFGPGLAETAVIRNGIDVARWPFA-VRKPRTGPP-------ELLY
TH_2191|M.thermoresistible__bu EEITELFGPGLSEIRVIRNGIDVAQWPFA-RRSPRSGPP-------RLLY
MLBr_00886|M.leprae_Br4923 SRVTAAFGP-RAALEYLPPGVDADRFRPDPASRAELRNRYRLGERPTVVC
MAB_1976|M.abscessus_ATCC_1997 GRFASAFGP-RAALEYLPSGVDTNRFCPDPAAREELRERYGLGDRPTIVC
Mvan_5245|M.vanbaalenii_PYR-1 RALLEQHNSMGTPIRVVHAGIDVGAYRFRARGVPAEGEVR-------ALT
Mflv_1501|M.gilvum_PYR-GCK RALLERHNPAGIPVRVVHAGIDTGRYHFRPRGIPTEGPVR-------ALT
MMAR_4514|M.marinum_M QEYASRLRLPTSRISVLPNAVRIPNTPVNQLGVQR----------VHAVA
: .:
MAV_4082|M.avium_104 VGRLVPRKGFDTIVRALPRIPDAELVIVGGPPAAELAGDEQARRLQRLAG
MSMEG_0933|M.smegmatis_MC2_155 VGRIQPLKAPDILLRAAAKLPGVRVLIAGGPSGSGLA---QPDTLVRLAD
Mb3058|M.bovis_AF2122/97 VGRLEYEKGVHDAIAALPRLR----RTHPGTTLTIAGEGTQQDWLIDQAR
Rv3032|M.tuberculosis_H37Rv VGRLEYEKGVHDAIAALPRLR----RTHPGTTLTIAGEGTQQDWLIDQAR
MUL_1919|M.ulcerans_Agy99 VGRLEYEKGVHNAIAALPRIR----RAHPGTTLTIAGEGTQQDWLVEQAR
TH_2191|M.thermoresistible__bu VGRLEYEKGVQDAIAALPRIR----RTHPGTTLTIAGTGTQHEWLVEQAR
MLBr_00886|M.leprae_Br4923 LARLVPRKGQDMLIRALPSIR----QRADGAALMIVGGGPYLGTLRKLAQ
MAB_1976|M.abscessus_ATCC_1997 VSRLVPRKGQDMLIEALPAIR----ERVDGAALVIVGGGPYAEPLRALAN
Mvan_5245|M.vanbaalenii_PYR-1 VASLQQYKGHAVLLEALAMGG----PEVDRITLDLIGDGVLRGDLEALVD
Mflv_1501|M.gilvum_PYR-GCK VASLQQYKGHAVLLEALAIGG----PAVERITLDLIGDGVLRPHLEALVE
MMAR_4514|M.marinum_M LGRLGVRKGSYDLIDAVAALD----ETVRNRLLATLAGDGDVAQVRAAVA
:. : *. : * . . : .
MAV_4082|M.avium_104 ELGVADRVRLLGGVTRAQMPALLRSADVVACTP-------WYEPFGIVPL
MSMEG_0933|M.smegmatis_MC2_155 ELGISDRVTFLPPQSREQLVNVYRAADLVAVPS-------YSESFGLVAV
Mb3058|M.bovis_AF2122/97 KHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEPFGLVAL
Rv3032|M.tuberculosis_H37Rv KHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEPFGLVAL
MUL_1919|M.ulcerans_Agy99 KHRVLKATKFLGHLEHAELLTLLHRADAAVFPS-------HYEPFGLVAL
TH_2191|M.thermoresistible__bu KHKVLKATRFVGQLGHEALLRQLHTADAAVLPS-------HYEPFGIVAL
MLBr_00886|M.leprae_Br4923 GCGVADHVIFAGGVAAVEVPAHYTLADVFAMPCRTRGGGMDVEGLGIVFL
MAB_1976|M.abscessus_ATCC_1997 RFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVFL
Mvan_5245|M.vanbaalenii_PYR-1 RLGLRDRVRFLGSCSEEAVRAALDAADLFVLPSIVADDG-QMEGLPVALM
Mflv_1501|M.gilvum_PYR-GCK RWGLRERVRFRGSCSEDVVRAALDAADLFVLPSLVADDG-QMEGLPVVLM
MMAR_4514|M.marinum_M KAGLGETIDVVGWLNPMARDELLRRAQIFVLPS-------RNEGLPMALL
: . .: . . * : :. :
MAV_4082|M.avium_104 EAMACGVPVVATAVGGIRDTVVDGATGRLVPPKDPDALGEAVAALLRDGR
MSMEG_0933|M.smegmatis_MC2_155 EAQACGTPVVAAAVGGLPVAVADGVSGALVDGHDIGDWADTISEVLD--R
Mb3058|M.bovis_AF2122/97 EAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPA
Rv3032|M.tuberculosis_H37Rv EAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPA
MUL_1919|M.ulcerans_Agy99 EAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVLDDPA
TH_2191|M.thermoresistible__bu EAAATGAPLVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVLDDPE
MLBr_00886|M.leprae_Br4923 EASATGVPVIAGKSGGAPEAVQHNKTGLVVDGRSVNMVADAVTELLTDRD
MAB_1976|M.abscessus_ATCC_1997 EASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQILVDPA
Mvan_5245|M.vanbaalenii_PYR-1 EALACGVPAVSTKLSGIPEIVVDGVTGLLATPGDAASLNATLTAMVQRGT
Mflv_1501|M.gilvum_PYR-GCK EALACGVPTVATDLSGIPEIVVDGVTGLLAQPGDAASLNRALTAMIERGG
MMAR_4514|M.marinum_M EAMANGLAPVTTTAGSIGEVVTDGVNGLLVGPAHADQLAHALGALVTDEN
** * * . :: .. * . .* :: ::
MAV_4082|M.avium_104 RGRTLGEAGRERARARYSWDRVAADTERIYERLS----------PARRGV
MSMEG_0933|M.smegmatis_MC2_155 EPAALSRASAEHA-AQFSWAHTVDALLASYSRAMSDYRARHPRPAARRSG
Mb3058|M.bovis_AF2122/97 AAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGER----QPQPRLPI
Rv3032|M.tuberculosis_H37Rv AAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGER----QPQPRLPI
MUL_1919|M.ulcerans_Agy99 AAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGER----QPLPRLPI
TH_2191|M.thermoresistible__bu GAQQRAVAARERLTADFDWHSVAAETAQVYLAAKRRER----EPLPRRLI
MLBr_00886|M.leprae_Br4923 RAAAMGAAGRHWVTAEWRWDTLAARLADLLCGNDSR--------------
MAB_1976|M.abscessus_ATCC_1997 RAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA----------------
Mvan_5245|M.vanbaalenii_PYR-1 AAVEFADAGRALVSREFDLRESIAALTGLLDEYLPPVAS-----------
Mflv_1501|M.gilvum_PYR-GCK DAEVFTGPGRELVTREFDLRESIDALTGLLDEYVPALPAQR---------
MMAR_4514|M.marinum_M LRARLGGAARERA-GEFGLDRWYQQLTRLWASLAGDPHPSRR--------
.. :
MAV_4082|M.avium_104 GTPSTRSG---
MSMEG_0933|M.smegmatis_MC2_155 RRFSMRRGVRT
Mb3058|M.bovis_AF2122/97 VEHALPDR---
Rv3032|M.tuberculosis_H37Rv VEHALPDR---
MUL_1919|M.ulcerans_Agy99 VEHALPDR---
TH_2191|M.thermoresistible__bu VEHALPDR---
MLBr_00886|M.leprae_Br4923 -----------
MAB_1976|M.abscessus_ATCC_1997 -----------
Mvan_5245|M.vanbaalenii_PYR-1 -----------
Mflv_1501|M.gilvum_PYR-GCK -----------
MMAR_4514|M.marinum_M -----------