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TRGISALVLIDAFRMGGAETLLAPMIVASRDTDVTMDVVSISPADWNSEKTMAILADAGIATRSLGIRRL LDPVALPRLVKTIRQGRYDIVHAHLEMAMTLAVPAAALVGRPAVCTFHHVARPLQGRAAWRERLAVEAAT RSRRALFVSEASRRSFAETYRPNRMPKNWEVMHNGIDISNFSPGQADPRVRSELAAGTQGPVVVLPAAFR DFKGIPVAIKAWPAVKQRFPTAVLALTGGGELEGELRRLVADLGLGDSVNFVGVRTDMPEVYRAADVVVL PSTHGENLPTVLIEASATACAIAASRVGGIPDIVLDGATGLLFEPGSADGLAEAVCRLLDDVELRRRMGA AASERARTEFSATAWLARLRTTYLEAMGVPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5246 | - | - | 100% (382) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_3550 | - | 6e-23 | 29.17% (360) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 3e-20 | 29.49% (312) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2211c | - | 2e-23 | 30.49% (328) | hypothetical protein Mb2211c |
| M. gilvum PYR-GCK | Mflv_1500 | - | 0.0 | 87.66% (381) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv2188c | - | 2e-23 | 30.49% (328) | hypothetical protein Rv2188c |
| M. leprae Br4923 | MLBr_00886 | - | 7e-23 | 28.53% (375) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_3366 | - | 1e-20 | 28.96% (297) | glycosyltransferase |
| M. marinum M | MMAR_4514 | - | 4e-23 | 30.58% (327) | glycosyl transferase |
| M. avium 104 | MAV_4082 | - | 3e-26 | 33.45% (287) | transferase |
| M. smegmatis MC2 155 | MSMEG_4253 | - | 2e-21 | 34.58% (214) | glycosyl transferase, group 1 family protein |
| M. thermoresistible (build 8) | TH_3188 | - | 3e-23 | 33.68% (291) | PUTATIVE glycosyl transferase, group 1 |
| M. ulcerans Agy99 | MUL_3543 | - | 5e-21 | 29.94% (314) | glycosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4082|M.avium_104 MRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYT-RRD
TH_3188|M.thermoresistible__bu ----MVSEHASPLAALGGVDAGGQNVHVAELSAALTRRGHEVTVYT-RRD
Mb2211c|M.bovis_AF2122/97 -----MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAPQWK
Rv2188c|M.tuberculosis_H37Rv -----MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAPQWK
MUL_3543|M.ulcerans_Agy99 -----MSRVLLVTNDFPPRRGGIQSYLSESVGRLVEAGSHSITVYAPQWK
MLBr_00886|M.leprae_Br4923 -----MSRVLLVTNDFPPRRGGIQSYLGEFVDRLINIGSHDVMVYAPQWT
MSMEG_4253|M.smegmatis_MC2_155 --------MLLVTNDFPPRRGGIQSYLEAFVGELVRT--HELTVYAPKWK
Mvan_5246|M.vanbaalenii_PYR-1 -----MTRGISALVLIDAFRMGGAETLLAPMIVASRDTDVTMDVVSISPA
Mflv_1500|M.gilvum_PYR-GCK -----MTGGVSALVLIDAFRMGGAETLLAPMIVASRDTDVSMDVVSISPS
MAB_3366|M.abscessus_ATCC_1997 ------MRILMVSWEYPPVVIGGLGRHVHHLSTELAAAGHDVVVLTRRPS
MMAR_4514|M.marinum_M ----------MNSVGVPTPQDRLRVLVVGPAPAAATSRGGMATVIALMAA
* :
MAV_4082|M.avium_104 DPRL---PDSVETPHGYSVVHVPAGPARVLPKDELLQYMYGF--------
TH_3188|M.thermoresistible__bu DRGL---PDRVDTPLGYTVVHVPAGPAEQLPKDELLPYMGPF--------
Mb2211c|M.bovis_AF2122/97 GADA---FDDAARAAGYRVVRHPS--TVMLPGPTVDVRMR----------
Rv2188c|M.tuberculosis_H37Rv GADA---FDDAARAAGYRVVRHPS--TVMLPGPTVDVRMR----------
MUL_3543|M.ulcerans_Agy99 GAQG---YDDVARAAGYRVVRHPS--TLMLPVPTVDSRMR----------
MLBr_00886|M.leprae_Br4923 GADT---FDNAAHDGGYQVVRHPG--TLMLPGPAVDARMR----------
MSMEG_4253|M.smegmatis_MC2_155 GAEE---YDEKAARSGYRVVRHPT--TLMLPEPTVASRMK----------
Mvan_5246|M.vanbaalenii_PYR-1 DWNS---EKTMAILADAGIATRSLGIRRLLDPVALPRLVK----------
Mflv_1500|M.gilvum_PYR-GCK EWNS---EKTMTILAEAGIPTRSLGIRRLLDPVALPRLVR----------
MAB_3366|M.abscessus_ATCC_1997 GTDPSSHPTSDEISEGVRVVAAAEDPHDFDFGTDMMAWTLAMGHAMVRAG
MMAR_4514|M.marinum_M HPDP-----HIHITAVPTFIDGPLWPRLMLGVRGMLRATW----------
. . :
MAV_4082|M.avium_104 AQFLRQQWCSDGPDVAHAHFWMSGVATQQAARAHSIPTVQTFHALGLTKR
TH_3188|M.thermoresistible__bu AQFLDAEWSAHRPDVVHAHFWMSGIATQLASRHLDLPAVQTFHALGVVKK
Mb2211c|M.bovis_AF2122/97 -------RLIAEHDIETVWFGAAAPLALLAPRARLAGASRVLAST----H
Rv2188c|M.tuberculosis_H37Rv -------RLIAEHDIETVWFGAAAPLALLAPRARLAGASRVLAST----H
MUL_3543|M.ulcerans_Agy99 -------RLIAQHDIDTVWFGAAAPLALLAPRARQAGATRVLAST----H
MLBr_00886|M.leprae_Br4923 -------RLIVDHGIDTVWFGSAAPLALLAPCARKAGATRVLAST----H
MSMEG_4253|M.smegmatis_MC2_155 -------RLIGEHDIETVWFGAAAPLALLGPLARRAGARRIVAST----H
Mvan_5246|M.vanbaalenii_PYR-1 ------TIRQGRYDIVHAHLEMAMTLAVPAAALVGRPAVCTFHHVARPLQ
Mflv_1500|M.gilvum_PYR-GCK ------TIRQGRYDVVHAHLEMAMTLAVPAAALAGRPAVCTFHHVARPLE
MAB_3366|M.abscessus_ATCC_1997 LALGLKGSGDWRPDVVHAHDWLVAHPAIALAEHFDVPLVSTLHATEAGRH
MMAR_4514|M.marinum_M ------LVLRKRADVLHVHLAHGGSVIRKALPLLAARLTGTPAIVHAHSY
.: .
MAV_4082|M.avium_104 LHQGSDDTSPDCRIDVEARVAREADWVAATSTDEVFELVRMGRARS-RTS
TH_3188|M.thermoresistible__bu RHQGAEDTSPQERLQLEAMVARGANWVAATCTDEVFELMRMGRSRS-RIS
Mb2211c|M.bovis_AF2122/97 GHEVGWSMLPVARSVLRR-IGDGTDVVTFVSSYTRSRFASAFGPAA-SLE
Rv2188c|M.tuberculosis_H37Rv GHEVGWSMLPVARSVLRR-IGDGTDVVTFVSSYTRSRFASAFGPAA-SLE
MUL_3543|M.ulcerans_Agy99 GHEVGWSMLPVAGSVLRR-IGDTTDIVTFVSRYTRSRFAPAFGPAA-SLE
MLBr_00886|M.leprae_Br4923 GHEVGWSMLPVARSVLRR-IGDVTDVVTFVSRYTRSRVTAAFGPRA-ALE
MSMEG_4253|M.smegmatis_MC2_155 GHEVGWSMLPVARTALRR-IGNDADVVTFVSRYTRSRFASAFGPSA-ALE
Mvan_5246|M.vanbaalenii_PYR-1 GRAAWRERLAVEAATRSR----RALFVSEASRRSFAETYRPNRMPK-NWE
Mflv_1500|M.gilvum_PYR-GCK GRAAWRERLAVEAATRSR----RALFVSEASRLSFAQNYRPKGMPA-NWE
MAB_3366|M.abscessus_ATCC_1997 SGWVS-GRISRQVHSVEWWLARESDSLITCSASMLDEVTQLFGPELPQVH
MMAR_4514|M.marinum_M DFGGWFDQLAPPARAAVRRMLAADHWVVLGERHVQEYASRLRLPTS-RIS
. :
MAV_4082|M.avium_104 VVPCGVDLDAFTP-DGPVAAR-------GARPRIVTVGRLVPRKGFDTIV
TH_3188|M.thermoresistible__bu VVPCGVDLDLFTP-DGPQAPR-------GERRRIVTVGRFVPRKGFDTLV
Mb2211c|M.bovis_AF2122/97 YLPPGVDTDRFRP-DPAARAELRKRYRLGERPTVVCLSRLVPRKGQDTLV
Rv2188c|M.tuberculosis_H37Rv YLPPGVDTDRFRP-DPAARAELRKRYRLGERPTVVCLSRLVPRKGQDTLV
MUL_3543|M.ulcerans_Agy99 YLPPGVDTDRFRP-DPAARAELRKRYQLGERPTVVCVSRLVPRKGQDTLI
MLBr_00886|M.leprae_Br4923 YLPPGVDADRFRP-DPASRAELRNRYRLGERPTVVCLARLVPRKGQDMLI
MSMEG_4253|M.smegmatis_MC2_155 HLPPGVDTDRFAP-DPDARARMRERYGLGDRPVVVCLSRLVPRKGQDMLI
Mvan_5246|M.vanbaalenii_PYR-1 VMHNGIDISNFSPGQADPRVRSELAAG-TQGPVVVLPAAFRDFKGIPVAI
Mflv_1500|M.gilvum_PYR-GCK VMHNGIDIANFAPGQADPGVRSELAGRDGDSLVAVLPAAFRDFKGIPVAI
MAB_3366|M.abscessus_ATCC_1997 VIRNGIDVTRWVFAPRPPADG--------TPPVLLFVGRLEYEKGIHDAI
MMAR_4514|M.marinum_M VLPNAVRIPNTPVNQLG-----------VQRVHAVALGRLGVRKGSYDLI
: .: : . : ** :
MAV_4082|M.avium_104 RALPRIPDAELVIVGGPPAAELAGDEQARRLQRLAGELGVADRVRLLGGV
TH_3188|M.thermoresistible__bu RALPAIPNAELVVVGGPRRSQLRTEPEARRLCTLAEELGVADRVQLYGSV
Mb2211c|M.bovis_AF2122/97 TALPSIR----RRVDGAALVIVGGGPYLETLRKLAHDCGVADHVTFTGGV
Rv2188c|M.tuberculosis_H37Rv TALPSIR----RRVDGAALVIVGGGPYLETLRKLAHDCGVADHVTFTGGV
MUL_3543|M.ulcerans_Agy99 KALPAIR----RRVDGAALVIVGGGPYLETLRKLARDCEVDEHVTFTSGV
MLBr_00886|M.leprae_Br4923 RALPSIR----QRADGAALMIVGGGPYLGTLRKLAQGCGVADHVIFAGGV
MSMEG_4253|M.smegmatis_MC2_155 RALPELR----RRVPDTALAIVGGGPYLETLQRMASDLGVAEHVVFTRGI
Mvan_5246|M.vanbaalenii_PYR-1 KAWPAVK----QRFPTAVLALTGGGELEGELRRLVADLGLGDSVNFVG--
Mflv_1500|M.gilvum_PYR-GCK KAWPAVI----EKFPSAVLALTGGGELESELRQLVADLGLGDSVNFVG--
MAB_3366|M.abscessus_ATCC_1997 AALPKIR----RAHPGTVLAVAGDGTQQDWLLEQARKYKVVKSVQFLGTL
MMAR_4514|M.marinum_M DAVAALD----ETVRNRLLATLAGDGDVAQVRAAVAKAGLGETIDVVGWL
* . : : . : . : .
MAV_4082|M.avium_104 TRAQMPALLRSADVVACTPWY-------EPFGIVPLEAMACGVPVVATAV
TH_3188|M.thermoresistible__bu ARADMPAVLRSADVVACTPWY-------EPFGIVPLEAMACGVPVVAAAV
Mb2211c|M.bovis_AF2122/97 ATDELPAHHALADVFAMPCRTRGAGMDVEGLGIVFLEASAAGVPVIAGNS
Rv2188c|M.tuberculosis_H37Rv ATDELPAHHALADVFAMPCRTRGAGMDVEGLGIVFLEASAAGVPVIAGNS
MUL_3543|M.ulcerans_Agy99 PGEELPTHHAMADVFAMPCRTRGSGMDVEGLGIVFLEASASGVPVIAGES
MLBr_00886|M.leprae_Br4923 AAVEVPAHYTLADVFAMPCRTRGGGMDVEGLGIVFLEASATGVPVIAGKS
MSMEG_4253|M.smegmatis_MC2_155 PAEELPAHHAMADVFAMPCRTRGAGLDVEGLGIVYLEASACGVPVVAGRS
Mvan_5246|M.vanbaalenii_PYR-1 VRTDMPEVYRAADVVVLPSTHG------ENLPTVLIEASATACAIAASRV
Mflv_1500|M.gilvum_PYR-GCK VRTDMPEVYRAADVVVLPSTHG------ENLPTVLIESSATACAVAASRV
MAB_3366|M.abscessus_ATCC_1997 DHSELLHWLHHADAILLPSHY-------EPFGIVALEAAAAGTPLVTSTV
MMAR_4514|M.marinum_M NPMARDELLRRAQIFVLPSRN-------EGLPMALLEAMANGLAPVTTTA
*: . . * : . :*: * . . :
MAV_4082|M.avium_104 GGIRDTVVDGATGRLVPPKDPDALGEAVAALLRDGRRGRTLGEAGRERAR
TH_3188|M.thermoresistible__bu GGMLDTVVHDVTGRLVPPRRPAELADTINQLLRDSFLRQSLGAAGRDRAR
Mb2211c|M.bovis_AF2122/97 GGAPETVQHNKTGLVVDGRSVDRVADAVAELLIDRDRAVAMGAAGREWVT
Rv2188c|M.tuberculosis_H37Rv GGAPETVQHNKTGLVVDGRSVDRVADAVAELLIDRDRAVAMGAAGREWVT
MUL_3543|M.ulcerans_Agy99 GGAPETVQHNKTGLVVDGNSVDKVAGAVIEVLADRDRAARMGDAGRQWVT
MLBr_00886|M.leprae_Br4923 GGAPEAVQHNKTGLVVDGRSVNMVADAVTELLTDRDRAAAMGAAGRHWVT
MSMEG_4253|M.smegmatis_MC2_155 GGAPETVLDGKTGTVVDGTDVDAITTAVGDLLADPRRAAAMGVAGRHWAL
Mvan_5246|M.vanbaalenii_PYR-1 GGIPDIVLDGATGLLFEPGSADGLAEAVCRLLDDVELRRRMGAAASERAR
Mflv_1500|M.gilvum_PYR-GCK GGIPDIVLDGQTGLLFEAGSVEGFADTVCRLLGDAELRRRLGAAASERAR
MAB_3366|M.abscessus_ATCC_1997 GGLGEAVIDGETGMSFAPRDVAGIAEAVTRTLDDPAAAAERAVAARARLT
MMAR_4514|M.marinum_M GSIGEVVTDGVNGLLVGPAHADQLAHALGALVTDENLRARLGGAARERAG
*. : * .. .* . . :: : * . *.
MAV_4082|M.avium_104 ARYSWDRVAADTERIYERLSPARRGVGTPSTRSG------
TH_3188|M.thermoresistible__bu ARYSWDRVATDTQRIYDRLVPADYRSATASQMSSG-----
Mb2211c|M.bovis_AF2122/97 AQWRWDTLAAKLADFLRGDDAAR-----------------
Rv2188c|M.tuberculosis_H37Rv AQWRWDTLAAKLADFLRGDDAAR-----------------
MUL_3543|M.ulcerans_Agy99 SQWRWDTLAARLAELLRGDDAGR-----------------
MLBr_00886|M.leprae_Br4923 AEWRWDTLAARLADLLCGNDSR------------------
MSMEG_4253|M.smegmatis_MC2_155 DNWQWRTRGARLAELLSGRREARQA---------------
Mvan_5246|M.vanbaalenii_PYR-1 TEFSATAWLARLRTTYLEAMGVPR----------------
Mflv_1500|M.gilvum_PYR-GCK SEFSATAWLARLRTTYLEAMGDRR----------------
MAB_3366|M.abscessus_ATCC_1997 ADFDWATVADETAQVYLAAKRREREPLGRSVIVERPLPDR
MMAR_4514|M.marinum_M -EFGLDRWYQQLTRLWASLAGDPHPSRR------------
: