For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LNRRHVTYLVSRFPVTSETFIVRELEALDRSGEFELEIRSLFPSPDRAVHEIARRWNEHLVRPSAFDAAA GVTWALLTRPIALMTILANVVAGYRRRLPLLVRALMTVPLACAHARDLARRAQPCHVHAHYATYPALAAW VCHRLAGTSYSFTVHAHDLYVDTSMLDRKIAEARYVVTISHYNRALLERHNPAGIPVRVVHAGIDTGRYH FRPRGIPTEGPVRALTVASLQQYKGHAVLLEALAIGGPAVERITLDLIGDGVLRPHLEALVERWGLRERV RFRGSCSEDVVRAALDAADLFVLPSLVADDGQMEGLPVVLMEALACGVPTVATDLSGIPEIVVDGVTGLL AQPGDAASLNRALTAMIERGGDAEVFTGPGRELVTREFDLRESIDALTGLLDEYVPALPAQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1501 | - | - | 100% (412) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_1500 | - | 2e-14 | 30.87% (311) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 9e-14 | 30.10% (196) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 1e-16 | 27.18% (287) | transferase |
| M. tuberculosis H37Rv | Rv3032 | - | 1e-16 | 27.18% (287) | transferase |
| M. leprae Br4923 | MLBr_01715 | - | 4e-19 | 27.53% (287) | putative transferase |
| M. abscessus ATCC 19977 | MAB_1976 | - | 1e-17 | 28.42% (285) | hypothetical protein MAB_1976 |
| M. marinum M | MMAR_1681 | - | 1e-15 | 27.30% (282) | transferase |
| M. avium 104 | MAV_3879 | - | 2e-17 | 29.00% (231) | glycosyl transferase, group 1 family protein |
| M. smegmatis MC2 155 | MSMEG_4253 | - | 5e-13 | 27.51% (229) | glycosyl transferase, group 1 family protein |
| M. thermoresistible (build 8) | TH_2191 | - | 3e-18 | 28.98% (283) | POSSIBLE TRANSFERASE |
| M. ulcerans Agy99 | MUL_1919 | - | 1e-15 | 27.30% (282) | transferase |
| M. vanbaalenii PYR-1 | Mvan_5245 | - | 0.0 | 80.30% (406) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3058|M.bovis_AF2122/97 ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
Rv3032|M.tuberculosis_H37Rv ------------------------MRILMVSWEYPPVVIGGLGRHVHHLS
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIGGLGRHVHHLS
MAV_3879|M.avium_104 ------------------------MKILMVSWEYPPVVIGGLGRHVHHLS
MMAR_1681|M.marinum_M ------------------------MKILMVSWEYPPVVIGGLGRHVHHLA
MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYPPVVIGGLGRHVHHLA
TH_2191|M.thermoresistible__bu ------------------------MKILMVSWEYPPVVVGGLGRHVYHLS
MAB_1976|M.abscessus_ATCC_1997 ---------------MTFHPGGLRQRILLVTNDFPPR-PGGIQSYLQEMV
MSMEG_4253|M.smegmatis_MC2_155 --------------------------MLLVTNDFPPR-RGGIQSYLEAFV
Mflv_1501|M.gilvum_PYR-GCK ---------------------MNRRHVTYLVSRFPVT----SETFIVREL
Mvan_5245|M.vanbaalenii_PYR-1 ---------------------MSRRDVVYLVSRFPVT----SETFIVREI
: : :* .:
Mb3058|M.bovis_AF2122/97 TALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFG
Rv3032|M.tuberculosis_H37Rv TALAAAGHDVVVLSRCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFG
MLBr_01715|M.leprae_Br4923 TALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPHEFTFS
MAV_3879|M.avium_104 TALAAAGHDVVVLSRRPTGTDPRTHPSTDQISEGVRVIAAAQDPHEFTFG
MMAR_1681|M.marinum_M TALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEFSFG
MUL_1919|M.ulcerans_Agy99 TALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEFSFG
TH_2191|M.thermoresistible__bu TALAAAGHEVVVLSRRPTGTDPSTHPSTDEVRDGVRVLAAAQDPHEFDFG
MAB_1976|M.abscessus_ATCC_1997 SRLAGS-HEVTVYAPRWKGCERYDAAAE---YQVVRHPTSLMLP-GPGVR
MSMEG_4253|M.smegmatis_MC2_155 GELVRT-HELTVYAPKWKGAEEYDEKAARSGYRVVRHPTTLMLP-EPTVA
Mflv_1501|M.gilvum_PYR-GCK EALDRSGEFELEIRSLFPSPDRAVHEIARRWNEHLVRPSAFDAAAGVTWA
Mvan_5245|M.vanbaalenii_PYR-1 EALDRSGKFHVEIRSLFPSPDEPVHDIARRWSRHLVRPTARDAATGLAWA
* : . . : : :: .
Mb3058|M.bovis_AF2122/97 NDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDWLVAHPA
Rv3032|M.tuberculosis_H37Rv NDMMAWTLAMGHAMIRAGLR----LKKLGTDRSWRPDVVHAHDWLVAHPA
MLBr_01715|M.leprae_Br4923 NDMMAWTLAMGHAMIRTGLS----LTRHSSDLPWRPDVVHAHDWLVAHPA
MAV_3879|M.avium_104 TDMMAWTLAMGHAMIRAGLPPKLHDKKPGGNRPWRPDVVHAHDWLVAHPA
MMAR_1681|M.marinum_M SDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDWLVAHPA
MUL_1919|M.ulcerans_Agy99 SDMMAWTLAMGHAMVRAGLT----LSGPGAEQPWQPDIVHAHDWLVAHPA
TH_2191|M.thermoresistible__bu RDMMAWTLAMGHSMVRAGLALG--LRGGTGGTPWQPDVVHAHDWLVAHPA
MAB_1976|M.abscessus_ATCC_1997 RRMVDLIRAQHADVVWFGAA---------------------------APL
MSMEG_4253|M.smegmatis_MC2_155 SRMKRLIGEHDIETVWFGAA---------------------------APL
Mflv_1501|M.gilvum_PYR-GCK LLTRPIALMTILANVVAGYRRRLPLLVRALMTVPLACAHARDLARRAQPC
Mvan_5245|M.vanbaalenii_PYR-1 LLTRPIAVMSVLATVTSGYLRRPPLLVRALTTVPIACAHARDLARRGRPC
: * *
Mb3058|M.bovis_AF2122/97 IALAQFYDVPMVSTIHAT-EAGRHSGWVSGALSRQVHAVESWLVRESDSL
Rv3032|M.tuberculosis_H37Rv IALAQFYDVPMVSTIHAT-EAGRHSGWVSGALSRQVHAVESWLVRESDSL
MLBr_01715|M.leprae_Br4923 ITLAQFYDVPMVSTIHAT-EAGRHSGWVSGALSRQVHAVESWLVRESDSL
MAV_3879|M.avium_104 IALAQFYDVPMVSTIHAT-EAGRHSGWVSGPISRQVHAIESWLVRESDSL
MMAR_1681|M.marinum_M IALADYYDVPMVSTIHAT-EAGRHSGWVSGDLSRQVHAVESWLVRESDSL
MUL_1919|M.ulcerans_Agy99 IALADYYDVPMVSTIHAT-EAGRHSGWVSGDLSRQVHAVESWLVRESDSL
TH_2191|M.thermoresistible__bu IALAEFFDVPLVSTIHAT-EAGRHSGWVSGPISRQVHAVESWLVRDSDSL
MAB_1976|M.abscessus_ATCC_1997 ALLSSAAKAAGAAVTAAS-THGHEVGWSMLPVAR---SALRQIGESTDVI
MSMEG_4253|M.smegmatis_MC2_155 ALLGPLARRAGARRIVAS-THGHEVGWSMLPVAR---TALRRIGNDADVV
Mflv_1501|M.gilvum_PYR-GCK HVHAHYATYPALAAWVCHRLAGTSYSFTVHAHDLYVDTSMLDRKIAEARY
Mvan_5245|M.vanbaalenii_PYR-1 HVHAHYATYPALAAWVCRRLAGISYSFTVHAHDLYVDMSMLDRKIADACY
. . . * .:
Mb3058|M.bovis_AF2122/97 ITCSASMNDEITELFGPGLAEITVIRNGIDAARWP--------FAARRPR
Rv3032|M.tuberculosis_H37Rv ITCSASMNDEITELFGPGLAEITVIRNGIDAARWP--------FAARRPR
MLBr_01715|M.leprae_Br4923 ITCSASMCNEIIELFGPGLAEITVIRNGIDPARWP--------FAARRAR
MAV_3879|M.avium_104 ITCSASMADEITELFGPGLAQITVIRNGIETARWP--------FAPRRPR
MMAR_1681|M.marinum_M ITCSGSMSDEITELFGPGLAETAVIRNGIDAARWP--------FAVRKPR
MUL_1919|M.ulcerans_Agy99 ITCSGSMSDEITELFGPGLAETAVIRNGIDVARWP--------FAVRKPR
TH_2191|M.thermoresistible__bu ITCSASMSEEITELFGPGLSEIRVIRNGIDVAQWP--------FARRSPR
MAB_1976|M.abscessus_ATCC_1997 TYVSRYTRGRFASAFGP-RAALEYLPSGVDTNRFCPDPAAREELRERYGL
MSMEG_4253|M.smegmatis_MC2_155 TFVSRYTRSRFASAFGP-SAALEHLPPGVDTDRFAPDPDARARMRERYGL
Mflv_1501|M.gilvum_PYR-GCK VVTISHYNRALLERHNPAGIPVRVVHAGIDTGRYH-------FRPRGIPT
Mvan_5245|M.vanbaalenii_PYR-1 VVTISQYNRALLEQHNSMGTPIRVVHAGIDVGAYR-------FRARGVPA
: . ... : *:: :
Mb3058|M.bovis_AF2122/97 TGPAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLI
Rv3032|M.tuberculosis_H37Rv TGPAELLYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLI
MLBr_01715|M.leprae_Br4923 TGPAELLYVGRLEYEKGVHDVIAALPRIRRSYPGTTLTIAGEGTQQDWLV
MAV_3879|M.avium_104 TGPAELLYLGRLEYEKGVHDVIAALPRIRRTHPGTTLTIAGEGTQQGWLI
MMAR_1681|M.marinum_M TGPPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEGTQQDWLV
MUL_1919|M.ulcerans_Agy99 TGPPELLYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGEGTQQDWLV
TH_2191|M.thermoresistible__bu SGPPRLLYVGRLEYEKGVQDAIAALPRIRRTHPGTTLTIAGTGTQHEWLV
MAB_1976|M.abscessus_ATCC_1997 GDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGGPYAEPLR
MSMEG_4253|M.smegmatis_MC2_155 GDRPVVVCLSRLVPRKGQDMLIRALPELRRRVPDTALAIVGGGPYLETLQ
Mflv_1501|M.gilvum_PYR-GCK EGPVRALTVASLQQYKGHAVLLEALAIGGPAVERITLDLIGDGVLRPHLE
Mvan_5245|M.vanbaalenii_PYR-1 EGEVRALTVASLQQYKGHAVLLEALAMGGPEVDRITLDLIGDGVLRGDLE
. : :. * ** : **. :* : * * *
Mb3058|M.bovis_AF2122/97 DQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEPFG
Rv3032|M.tuberculosis_H37Rv DQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEPFG
MLBr_01715|M.leprae_Br4923 DQARKYKVIKATRFVGHLNHNELLAALQRADAAVLPS-------HYEPFG
MAV_3879|M.avium_104 EQARKHRVLKAIRFVGHLEHSELLAMLHRADAAVLPS-------HYEPFG
MMAR_1681|M.marinum_M EQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPS-------HYEPFG
MUL_1919|M.ulcerans_Agy99 EQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPS-------HYEPFG
TH_2191|M.thermoresistible__bu EQARKHKVLKATRFVGQLGHEALLRQLHTADAAVLPS-------HYEPFG
MAB_1976|M.abscessus_ATCC_1997 ALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLG
MSMEG_4253|M.smegmatis_MC2_155 RMASDLGVAEHVVFTRGIPAEELPAHHAMADVFAMPCRTRGAGLDVEGLG
Mflv_1501|M.gilvum_PYR-GCK ALVERWGLRERVRFRGSCSEDVVRAALDAADLFVLPSLVADDG-QMEGLP
Mvan_5245|M.vanbaalenii_PYR-1 ALVDRLGLRDRVRFLGSCSEEAVRAALDAADLFVLPSIVADDG-QMEGLP
. : * : .* .:*. . * :
Mb3058|M.bovis_AF2122/97 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL
Rv3032|M.tuberculosis_H37Rv LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVL
MLBr_01715|M.leprae_Br4923 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRDIAELAAMVCTVL
MAV_3879|M.avium_104 IVALEAAAAGTPLVTSNIGGLGEAVIDGQTGVSCPPRDVPALAAAIRTVL
MMAR_1681|M.marinum_M LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL
MUL_1919|M.ulcerans_Agy99 LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRDVAALAAAVCGVL
TH_2191|M.thermoresistible__bu IVALEAAATGAPLVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVL
MAB_1976|M.abscessus_ATCC_1997 IVFLEASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQIL
MSMEG_4253|M.smegmatis_MC2_155 IVYLEASACGVPVVAGRSGGAPETVLDGKTGTVVDGTDVDAITTAVGDLL
Mflv_1501|M.gilvum_PYR-GCK VVLMEALACGVPTVATDLSGIPEIVVDGVTGLLAQPGDAASLNRALTAMI
Mvan_5245|M.vanbaalenii_PYR-1 VALMEALACGVPAVSTKLSGIPEIVVDGVTGLLATPGDAASLNATLTAMV
:. :** * *.* *: .* * * * ** . : : ::
Mb3058|M.bovis_AF2122/97 DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPI
Rv3032|M.tuberculosis_H37Rv DDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPI
MLBr_01715|M.leprae_Br4923 EDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRLPI
MAV_3879|M.avium_104 DDPEAAQRRACAARERLTSDFDWHTVADKTAQVYLSAKRAERQPQARLPI
MMAR_1681|M.marinum_M DDPAAAQQRARAARERLNSDFDWQTVAEQTAQVYLAAKRGERQPLPRLPI
MUL_1919|M.ulcerans_Agy99 DDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGERQPLPRLPI
TH_2191|M.thermoresistible__bu DDPEGAQQRAVAARERLTADFDWHSVAAETAQVYLAAKRREREPLPRRLI
MAB_1976|M.abscessus_ATCC_1997 VDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA------------
MSMEG_4253|M.smegmatis_MC2_155 ADPRRAAAMGVAGRHWALDNWQWRTRGARLAELLSGRREARQA-------
Mflv_1501|M.gilvum_PYR-GCK ERGGDAEVFTGPGRELVTREFDLRESIDALTGLLDEYVPALPAQR-----
Mvan_5245|M.vanbaalenii_PYR-1 QRGTAAVEFADAGRALVSREFDLRESIAALTGLLDEYLPPVAS-------
* ..* :: : :
Mb3058|M.bovis_AF2122/97 VEHALPDR
Rv3032|M.tuberculosis_H37Rv VEHALPDR
MLBr_01715|M.leprae_Br4923 VEHALPDR
MAV_3879|M.avium_104 VEHALPDR
MMAR_1681|M.marinum_M VEHALPDR
MUL_1919|M.ulcerans_Agy99 VEHALPDR
TH_2191|M.thermoresistible__bu VEHALPDR
MAB_1976|M.abscessus_ATCC_1997 --------
MSMEG_4253|M.smegmatis_MC2_155 --------
Mflv_1501|M.gilvum_PYR-GCK --------
Mvan_5245|M.vanbaalenii_PYR-1 --------