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M. vanbaalenii PYR-1 Mvan_5257 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 5632895 - 5633896
length: 333

DFSPDEGQQAVADVVTSVLERDNTWDALVSGGVTALGVPERLGGDGVGFAEMATALTEIGRHGTISPALV
TLGTTAVLLDLASEAQQDRYLGGVAKGSVLTLALNEPGAQLPDRPAVALAAGKLNGTKVGVGYAAQADWI
VVTTDNGVVVVPGKADGLTVTKTPTSNGSDEYVLAFADVAVADADVLEGATPHRVNQLVLAAVGAFSAGL
VAGALRLTADYVATREQFGRPLSTFQTVAAQLSEVYIASRTISLLSTSVAWQLTEGRDAADDLAILGYWL
ASQAPPAMRLCHHLHGGMGMDITYPMDRYYSSIKDLTRLLGGPSHRLDLVGA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_5257 - - 100% (333) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_5207 - 1e-31 30.72% (319) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4955 - 4e-23 30.30% (297) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3574c fadE28 1e-137 71.26% (334) acyl-CoA dehydrogenase FADE28
M. gilvum PYR-GCK Mflv_1509 - 1e-160 83.78% (333) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3544c fadE28 1e-137 71.26% (334) acyl-CoA dehydrogenase FADE28
M. leprae Br4923 MLBr_00737 fadE25 2e-13 24.53% (322) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0614 - 1e-101 53.28% (351) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5031 fadE28 1e-132 69.53% (338) acyl-CoA dehydrogenase FadE28
M. avium 104 MAV_0617 - 1e-140 73.80% (332) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5994 - 1e-147 78.44% (334) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_0363 fadE28 1e-139 73.00% (337) PROBABLE ACYL-CoA DEHYDROGENASE FADE28
M. ulcerans Agy99 MUL_4105 fadE28 1e-133 69.53% (338) acyl-CoA dehydrogenase FadE28

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_5257|M.vanbaalenii_PYR-1       ----------MDFSPDEGQQAVADVVTSVLER----------------DN
Mflv_1509|M.gilvum_PYR-GCK          ----------MDFSPDEGQQAVADVVTSVLER----------------DN
MSMEG_5994|M.smegmatis_MC2_155      ----------MDFTPNPEQQAVADVVTSVLER----------------DN
Mb3574c|M.bovis_AF2122/97           ----------MDFDPTAEQQAVADVVTSVLER----------------DI
Rv3544c|M.tuberculosis_H37Rv        ----------MDFDPTAEQQAVADVVTSVLER----------------DI
MMAR_5031|M.marinum_M               ----------MDFEPTAEQQAVADVVTSVLAR----------------DL
MUL_4105|M.ulcerans_Agy99           ----------MDFEPTAEQQAVADVVTSVLAR----------------DL
MAV_0617|M.avium_104                ----MASETTMDFDPSPTQQAVADVVTSVLDR----------------EL
TH_0363|M.thermoresistible__bu      ----------VDFSPNEGQQAVADVVTSVLSR----------------ET
MAB_0614|M.abscessus_ATCC_1997      ----------MDFAFAEEQQAVSDVVEAVLADREFVGVVPEIG---YDEA
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                *     :: :  .: ::                   : 

Mvan_5257|M.vanbaalenii_PYR-1       TWDALVSGGVTALGVPERLGGDGVGFAEMATALTEIGRHGTISPALVTLG
Mflv_1509|M.gilvum_PYR-GCK          TWDALVSGGVTALAVPERLGGDGVGLAEIATALTEIGRHGTVSPALVTLG
MSMEG_5994|M.smegmatis_MC2_155      SWDALVSGGVTALAVPERLGGDGLGLAEVATALTEIGRRGTVSPALATLG
Mb3574c|M.bovis_AF2122/97           SWEALVCGGVTALPVPERLGGDGVGLFEVGALLTEVGRHGAVTPALATLG
Rv3544c|M.tuberculosis_H37Rv        SWEALVCGGVTALPVPERLGGDGVGLFEVGALLTEVGRHGAVTPALATLG
MMAR_5031|M.marinum_M               TWTALVDGGVTALAVPERLGGDGVGLLEVSTVLAEVGRHGAVTPALATLG
MUL_4105|M.ulcerans_Agy99           TWTALVDGGVTALAVPERLGGDGVGLLEVSTVLAEVGRHGAVTPALATLG
MAV_0617|M.avium_104                SWEALVDGGVTALPVPERLGGDGVGLPEVATVLTEVGRRGAITPALATLG
TH_0363|M.thermoresistible__bu      SWDALVSGGVAALPVPERLGGDGVGLAEVATALTEIGRHGAVGPALATLG
MAB_0614|M.abscessus_ATCC_1997      AWRALAANGVLSLALPERLGGDGLGLAEVSVALRVLGKHGALTPALATLG
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                    :  **  .*. :: :**. **:* .       :  :.: .:  . : ::.

Mvan_5257|M.vanbaalenii_PYR-1       -TTAV-LLDLASEAQQDRYLGG-VAKGSVLTLALNEPGAQLPDRPAVALA
Mflv_1509|M.gilvum_PYR-GCK          -ATAV-LLDLAADTQQNRYLAG-VAKGSVVTLALNEPGVSLPDHPGVTLA
MSMEG_5994|M.smegmatis_MC2_155      -LGLVPLLDLASEAQQDRYLAQ-VDKGAVLSAALSEPGRHLPQQPATTFA
Mb3574c|M.bovis_AF2122/97           -LGVVPLLELASAEQQDRFLAG-VAKGGVLTAALNEPGAALPDRPATSFV
Rv3544c|M.tuberculosis_H37Rv        -LGVVPLLELASAEQQDRFLAG-VAKGGVLTAALNEPGAALPDRPATSFV
MMAR_5031|M.marinum_M               -LGVVPLLALASEAQQDRILAG-VAKGAVLSAALNEPGVALPDRPATRFA
MUL_4105|M.ulcerans_Agy99           -LGVVPLLALASEAQQDRILAG-VAKGAVLSAALNEPGVALPDRPATRFA
MAV_0617|M.avium_104                -FAVLPLLELASEEQQDRFLAG-VARGGVLTAALNEPGTPLPDRPATTFA
TH_0363|M.thermoresistible__bu      -LAVTPLLELASEEQQDRYLAG-VAEGAILTAALNEPGAALPDRPATSLR
MAB_0614|M.abscessus_ATCC_1997      -FGVVPLVELASGEQQDRYLAG-VGDGAILTAALDEPGRAVPSAPAVSAV
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                          *:  .:   :.: *   .  *.: : **.*        .     

Mvan_5257|M.vanbaalenii_PYR-1       --AGK---LNGTKVGVGYAAQADWIVVTTDN---------GVVVVPGKAD
Mflv_1509|M.gilvum_PYR-GCK          --GGR---LNGTKIAVGYAAQADWLVVTTDS---------GVVVVPGDAD
MSMEG_5994|M.smegmatis_MC2_155      --GGV---LNGTKIGVPYAGSAQWLVVTADT---------AVVVVSPTAA
Mb3574c|M.bovis_AF2122/97           --GGR---LSGTKVGVGYAEQADWMLVTADN---------AVVVVSPTAD
Rv3544c|M.tuberculosis_H37Rv        --GGR---LSGTKVGVGYAEQADWMLVTADN---------AVVVVSPTAD
MMAR_5031|M.marinum_M               --NGR---LSGTKLGVAYAGQADWLIVTADG---------AVVVVSPKAD
MUL_4105|M.ulcerans_Agy99           --NGR---LSGTKLGVAYAGQADWLIVTADG---------AVVVVSSKAD
MAV_0617|M.avium_104                --DGR---LSGTKIGVGYAAQADWMIVTADS---------AVVVVSPKAD
TH_0363|M.thermoresistible__bu      --GGK---LNGTKVAVGYAAQAQWMVVSTDA---------GVVVVSPNAA
MAB_0614|M.abscessus_ATCC_1997      R-DGSSLVLNGRKIGVLHAAEAHWILVTTDN---------GVVVVAPNTP
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDE
                                       *    *.* *  :  . .: *  * :           ...:*     

Mvan_5257|M.vanbaalenii_PYR-1       GLTVTKTPTSN---GSDEYVLAFADVAVADADVLEGA-----TPHRVNQL
Mflv_1509|M.gilvum_PYR-GCK          GIAVTVTPTAN---GGEEAAVTFTDVAVSDDDVLAGA-----EVSRVNQL
MSMEG_5994|M.smegmatis_MC2_155      GVTLTKTPTAN---GSDEYAVTFADVAVSDDDVLAGA-----TATRVNQL
Mb3574c|M.bovis_AF2122/97           GVRMVRTPTSN---GSDEYVMTMDGVAVADCDILADV-----AAHRVNQL
Rv3544c|M.tuberculosis_H37Rv        GVRMVRTPTSN---GSDEYVMTMDGVAVADCDILADV-----AAHRVNQL
MMAR_5031|M.marinum_M               GVQLVQTPTSN---GSVEYTVSFHDVVVSESDVLAGA-----TAPRVNQL
MUL_4105|M.ulcerans_Agy99           GVQLVQTPTSN---GSVEYTVSFHDVVVSESDVLAGA-----TAPRVNQL
MAV_0617|M.avium_104                GVQVVQTPTSN---GSDEYTVSFTGVAVADSDVLAGA-----TAARVNQL
TH_0363|M.thermoresistible__bu      GVQITKSPTAN---GTDEYSVTFTDVEVPDADVLDGA-----TVARLNQY
MAB_0614|M.abscessus_ATCC_1997      GVTITRTPTAS---KAAEYAVTFSDVSVPAADQLSG------SVQRLNEL
MLBr_00737|M.leprae_Br4923          GFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDH
                                    *. :  . .           : :    :.    :              : 

Mvan_5257|M.vanbaalenii_PYR-1       VLAAVGAFSAGLVAGALRLTADYVATREQFGRPLSTFQTVAAQLSEVYIA
Mflv_1509|M.gilvum_PYR-GCK          SLAAIGAFAAGLVAGALRLTADYVANREQFGRPLSTFQTVAAQLSEVYIA
MSMEG_5994|M.smegmatis_MC2_155      ALAAIGAFGAGLVAGALRLTADYVATREQFGRPLSTFQTVAAQLSEVYIA
Mb3574c|M.bovis_AF2122/97           ALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIA
Rv3544c|M.tuberculosis_H37Rv        ALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIA
MMAR_5031|M.marinum_M               ALAMLGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIA
MUL_4105|M.ulcerans_Agy99           ALAMLGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIA
MAV_0617|M.avium_104                ALAAVGAYADGLVSGALRLTADYVANRKQFGKPLSTFQTVAAQLAEVYIA
TH_0363|M.thermoresistible__bu      ALAAIGAYAAGLVAGALRLTADYVANREQFGKPLSTFQTVAAHLAEVYIA
MAB_0614|M.abscessus_ATCC_1997      ALAAIGSYADGLVSGALRLTADHVSNRVQFGKPLATFQAVSQQLADVYVV
MLBr_00737|M.leprae_Br4923          TRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMK
                                      . :*: . *:. ***  :  :.  * ***..::***::   *::: : 

Mvan_5257|M.vanbaalenii_PYR-1       SRTISLLSTSVAWQLTE----GRDAADDLAILGYWLASQAPPAMRLCHHL
Mflv_1509|M.gilvum_PYR-GCK          SRTIDLVSNSVVWRLSE----GLDAEDDLAILGYWLTSQAPPAMRLCHHL
MSMEG_5994|M.smegmatis_MC2_155      SRTIDLVSTSVVWRLSE----GLDAEEDLAILGFWLTTQAPPAMRLCHHL
Mb3574c|M.bovis_AF2122/97           SRTIDLVAKSVIWRLAE----DLDAGDDLGVLGYWVTSQAPPAMQICHHL
Rv3544c|M.tuberculosis_H37Rv        SRTIDLVAKSVIWRLAE----DLDAGDDLGVLGYWVTSQAPPAMQICHHL
MMAR_5031|M.marinum_M               SRTIDLAAKSVIWRLAAGRENDPQTGDDLDVLGYWVTSQAPPVMQICHHL
MUL_4105|M.ulcerans_Agy99           SRTIDLAAKSVIWRLAAGRENDPQTGDDLDVLGYWVTSQAPPVMQICHHL
MAV_0617|M.avium_104                SRTIDLVAKSVVWGLSE----GRDVDHDLGVLGYWVASQAPPAMQLCHHL
TH_0363|M.thermoresistible__bu      SRTLDLASTSVIWRLSEGPADDPQTREDLAVLGYWLAAEAPPVMQLCHHL
MAB_0614|M.abscessus_ATCC_1997      SRTLNLGVTSAVWRLCE----GLDATEDLDIVSFWMAAEAQRVMQICHHL
MLBr_00737|M.leprae_Br4923          VEAARLIVYAAAARAERG---EPDLGFISAASKCFASDIAMEVTTDAVQL
                                     .:  *   :.            :          : :  *  .   . :*

Mvan_5257|M.vanbaalenii_PYR-1       HGGMGMDITYPMDRYYSSIKDLTRLLGGPSHRLDLVGA------------
Mflv_1509|M.gilvum_PYR-GCK          HGGMGMDITYPMDRYYSSIKDLTRLLGGPTHRLDLVGA------------
MSMEG_5994|M.smegmatis_MC2_155      HGGMGMDITYPMDRYFSSIKDLTRLLGGPAHRLDLVGA------------
Mb3574c|M.bovis_AF2122/97           HGGMGMDVTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT-------
Rv3544c|M.tuberculosis_H37Rv        HGGMGMDVTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT-------
MMAR_5031|M.marinum_M               HGGMGMDVTYPMHRYYSTIKDLSRLLGGPAHRLDLVGAQCSST-------
MUL_4105|M.ulcerans_Agy99           HGGMGMDVTYPMHRYYSTIKDLSRLLGGPAHRLDLVGAQCSST-------
MAV_0617|M.avium_104                HGGMGMDITYPMHRYYSTIKDLTRLLGGPSHRLDLVAIASTAQPGAAGRH
TH_0363|M.thermoresistible__bu      HGGMGMDIDYPMDRYYSTIKDLTRLVGGPSRCLDRLGGLDLADAAVGGRG
MAB_0614|M.abscessus_ATCC_1997      HGGLGVDITYPMNRYYSTIKDLSRLVGGSSERLDVLAAAQG---------
MLBr_00737|M.leprae_Br4923          FGGAGYTSDFPVERFMRDAK-ITQIYEGTNQIQRVVMSRALLR-------
                                    .** *    :*:.*:    * ::::  *. .    :              

Mvan_5257|M.vanbaalenii_PYR-1       ----------
Mflv_1509|M.gilvum_PYR-GCK          ----------
MSMEG_5994|M.smegmatis_MC2_155      ----------
Mb3574c|M.bovis_AF2122/97           ----------
Rv3544c|M.tuberculosis_H37Rv        ----------
MMAR_5031|M.marinum_M               ----------
MUL_4105|M.ulcerans_Agy99           ----------
MAV_0617|M.avium_104                ADDLVGAQCS
TH_0363|M.thermoresistible__bu      PGDDGN----
MAB_0614|M.abscessus_ATCC_1997      ----------
MLBr_00737|M.leprae_Br4923          ----------

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_5257	-	-	100% (333)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_5207	-	1e-31	30.72% (319)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4955	-	4e-23	30.30% (297)	acyl-CoA dehydrogenase domain-containing protein