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PVPENVPEARVLVVDDEANIVELLSVSLKFQGFEVHTASNGPAALDKAREVRPDAIILDVMMPGMDGFGL LRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRSGRGHEEPRTSRLT FADIELDEDTHEVWKAGEPVSLSPTEFTLLRYFIINAGTVLSKPKILDHVWRYDFGGDVNVVESYVSYLR RKIDTGDKRLLHTLRGVGYVLREPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5175 | - | - | 100% (236) | two component transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4429 | - | 3e-67 | 54.67% (225) | two component transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2296 | - | 8e-62 | 52.65% (226) | two component transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0780 | phoP | 1e-121 | 90.21% (235) | two component system response transcriptional positive |
| M. gilvum PYR-GCK | Mflv_1581 | - | 1e-130 | 98.31% (236) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv0757 | phoP | 1e-121 | 90.21% (235) | two component system response transcriptional positive |
| M. leprae Br4923 | MLBr_00174 | - | 8e-55 | 47.56% (225) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_0673 | - | 1e-114 | 89.43% (227) | putative DNA-binding response regulator PhoP |
| M. marinum M | MMAR_4942 | phoP | 1e-121 | 90.64% (235) | two-component system response phosphate regulon |
| M. avium 104 | MAV_0701 | phoP | 1e-121 | 92.58% (229) | DNA-binding response regulator PhoP |
| M. smegmatis MC2 155 | MSMEG_5872 | phoP | 1e-127 | 96.58% (234) | DNA-binding response regulator PhoP |
| M. thermoresistible (build 8) | TH_1732 | phoP | 3e-57 | 50.22% (225) | DNA-binding response regulator PhoP |
| M. ulcerans Agy99 | MUL_0463 | phoP | 1e-121 | 90.21% (235) | two component system response phosphate regulon |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5175|M.vanbaalenii_PYR-1 ----------MP-VPENVPEARVLVVDDEANIVELLSVSLKFQGFEVHTA
Mflv_1581|M.gilvum_PYR-GCK --------MAMP-VPENVPEARVLVVDDEANIVELLSVSLKFQGFEVHTA
MSMEG_5872|M.smegmatis_MC2_155 --------MAMPALPENVPEARVLVVDDEANIVELLSVSLKFQGFEVHTA
Mb0780|M.bovis_AF2122/97 MRKGVDLVTAGTPGENTTPEARVLVVDDEANIVELLSVSLKFQGFEVYTA
Rv0757|M.tuberculosis_H37Rv MRKGVDLVTAGTPGENTTPEARVLVVDDEANIVELLSVSLKFQGFEVYTA
MMAR_4942|M.marinum_M -------MTATTPGEATTPEARILVVDDEDNIVELLSVSLKFQGFEVHTA
MUL_0463|M.ulcerans_Agy99 -------MTATTPGEATTPEARILVVDDEDNIVELLSVSLKFQGFEVHTA
MAV_0701|M.avium_104 -------MTSATP-TDAKPEARVLVVDDEANIVELLSVSLKFQGFEVHTA
MAB_0673|M.abscessus_ATCC_1997 MVSITTETHQGTFSANGTTPAKVLVVDDESNIVELLSVSLKFQGFDVYTA
MLBr_00174|M.leprae_Br4923 --------------------MRILAVDDDRAVRESLRRSLSFNGYSVELA
TH_1732|M.thermoresistible__bu ------------------VAVRILVVDDDRAVRESLRRSLSFNGYSVELA
::*.***: : * * **.*:*:.* *
Mvan_5175|M.vanbaalenii_PYR-1 SNGPAALDKAREVRPDAIILDVMMPGMDGFGLLRRLRADGIDAPALFLTA
Mflv_1581|M.gilvum_PYR-GCK SNGPAALDKAREVRPDAIILDVMMPGMDGFGLLRRLRADGIDAPALFLTA
MSMEG_5872|M.smegmatis_MC2_155 SNGAAALDKAREVRPDAVILDVMMPGMDGFGLLRRLRADGIDAPALFLTA
Mb0780|M.bovis_AF2122/97 TNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTA
Rv0757|M.tuberculosis_H37Rv TNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTA
MMAR_4942|M.marinum_M TNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTA
MUL_0463|M.ulcerans_Agy99 TNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLQADGIDAPALFLTA
MAV_0701|M.avium_104 TNGAQALDRAREARPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTA
MAB_0673|M.abscessus_ATCC_1997 DSGAAALDLARTVRPDAVILDVMMPGMDGFGVLRRLRADGIDAPTLFLTA
MLBr_00174|M.leprae_Br4923 NDGVEALEMVARDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTA
TH_1732|M.thermoresistible__bu EDGVEALDLIANDRPDAVVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTA
.* **: ****::****** :**: : *:*:: * * * *.***
Mvan_5175|M.vanbaalenii_PYR-1 RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRSGRGHEEPRTSR
Mflv_1581|M.gilvum_PYR-GCK RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRSGGRVQEPRTSR
MSMEG_5872|M.smegmatis_MC2_155 RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRSGRGVEETRNAR
Mb0780|M.bovis_AF2122/97 RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGNKEPRNVR
Rv0757|M.tuberculosis_H37Rv RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGNKEPRNVR
MMAR_4942|M.marinum_M RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGSAEPRNSR
MUL_0463|M.ulcerans_Agy99 RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGSAEPRNSR
MAV_0701|M.avium_104 RDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGGAEPRSAR
MAB_0673|M.abscessus_ATCC_1997 RDGLQDKIAGLTLGADDYVTKPFSLEEVVARLRVILRRSGMGSEPARKSR
MLBr_00174|M.leprae_Br4923 RDSVSERVAGLDAGADDYLPKPFALEELLARIRALLRRT-KPDDAAESVA
TH_1732|M.thermoresistible__bu RDSVSERVAGLDAGADDYLPKPFALEELLARLRALLRRT-TPDDAADSQK
**.:.:::*** *.***:.***:***::**:*.:***: . .
Mvan_5175|M.vanbaalenii_PYR-1 LTFADIELDEDTHEVWKAGEPVSLSPTEFTLLRYFIINAGTVLSKPKILD
Mflv_1581|M.gilvum_PYR-GCK LTFADIELDEDTHEVWKAGEPVSLSPTEFTLLRYFIINAGTVLSKPKILD
MSMEG_5872|M.smegmatis_MC2_155 LTFADIELDEDTHEVWKAGEPVSLSPTEFTLLRYFIINAGTVLSKPKILD
Mb0780|M.bovis_AF2122/97 LTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD
Rv0757|M.tuberculosis_H37Rv LTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD
MMAR_4942|M.marinum_M LTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD
MUL_0463|M.ulcerans_Agy99 LTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD
MAV_0701|M.avium_104 LTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILD
MAB_0673|M.abscessus_ATCC_1997 LSFADIELDEDTHEVWKAGEPVALSPTEFTLLRYFMINAGTVLSKPKILD
MLBr_00174|M.leprae_Br4923 MSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRILE
TH_1732|M.thermoresistible__bu LTFADLTLDPVTREVTRGNRQISLTRTEFALLELLIANPRRVLSRSRILE
::*:*: ** *:** :. . ::*: ***:**. :: *. **::.:**:
Mvan_5175|M.vanbaalenii_PYR-1 HVWRYDFGGDVNVVESYVSYLRRKIDT-GDKRLLHTLRGVGYVLREPR-
Mflv_1581|M.gilvum_PYR-GCK HVWRYDFGGDVNVVESYVSYLRRKIDT-GDKRLLHTLRGVGYVLREPR-
MSMEG_5872|M.smegmatis_MC2_155 HVWRYDFGGDVNVVESYVSYLRRKIDT-GEKRLLHTLRGVGYVLREPR-
Mb0780|M.bovis_AF2122/97 HVWRYDFGGDVNVVESYVSYLRRKIDT-GEKRLLHTLRGVGYVLREPR-
Rv0757|M.tuberculosis_H37Rv HVWRYDFGGDVNVVESYVSYLRRKIDT-GEKRLLHTLRGVGYVLREPR-
MMAR_4942|M.marinum_M HVWRYDFGGDVNVVESYVSYLRRKIDT-GDKRLLHTLRGVGYVLREPR-
MUL_0463|M.ulcerans_Agy99 HVWRYDFGGDVNVVESYVSYLRRKIDT-GDKRLLHTLRGVGYVLREPR-
MAV_0701|M.avium_104 HVWRYDFGGDVNVVESYVSYLRRKIDT-GEKRLLHTLRGVGYVLREPR-
MAB_0673|M.abscessus_ATCC_1997 HVWRYDFGGDVNVVESYVSYLRRKIDN-GEKRLLHTLRGVGYVLREPR-
MLBr_00174|M.leprae_Br4923 EVWGFDFPTSGNALEVYVGYLRRKTEADGESRLIHTVRGVGYVLRETPP
TH_1732|M.thermoresistible__bu EVWGFDFPTSGNALEVYIGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
.** :** . *.:* *:.***** : *: **:**:*********.