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SCPSVAGWRTAAAVLVVLAGPACAAPVGVTAPTLDSSKCSRDVLATQYPGILTFGADQPVYPPWYMGDDP TNGDGFESALAYALAAKLNYTGDDVRWVRVPFNTALAPGAKTFDVNLSQFSITEQRRAAVDFSTPYFDVT QAVVAVRTSPAAAVTTLDGLRPLRLGAQVGTTSHTAATELGGSVPVQAYNTNVDAKMALLDGEIDAMVVD LPTALTMAEELRHGVLVGQLPADGEHLEQFGIVLSHGSPLTRCVSWAVDSLREDGTLAGLQNRWLTDTGP VAVLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5107 | - | - | 100% (286) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_5576 | - | 3e-12 | 29.26% (229) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_1851 | - | 3e-10 | 30.84% (227) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 2e-13 | 32.14% (168) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_1232 | - | 1e-12 | 30.00% (230) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0411c | glnH | 2e-13 | 32.14% (168) | glutamine-binding lipoprotein |
| M. leprae Br4923 | MLBr_00303 | glnH | 5e-12 | 29.03% (217) | putative glutamine-binding protein |
| M. abscessus ATCC 19977 | MAB_4223 | - | 1e-10 | 24.71% (259) | glutamine-binding protein GlnH |
| M. marinum M | MMAR_0714 | glnH | 1e-11 | 30.95% (168) | glutamine-binding lipoprotein GlnH |
| M. avium 104 | MAV_4750 | - | 4e-12 | 29.82% (218) | extracellular solute-binding protein, family protein 3 |
| M. smegmatis MC2 155 | MSMEG_6307 | - | 3e-11 | 28.70% (230) | glutamine-binding periplasmic protein/glutamine transport |
| M. thermoresistible (build 8) | TH_2822 | - | 8e-63 | 44.44% (288) | PUTATIVE putative extracellular solute-binding protein, family |
| M. ulcerans Agy99 | MUL_2809 | glnH | 9e-12 | 30.95% (168) | glutamine-binding lipoprotein GlnH |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5107|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2822|M.thermoresistible__bu --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAV_4750|M.avium_104 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0714|M.marinum_M --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MAB_4223|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK MSRTLGRTRRACYGPPMGNPRRVLLAVLAALAVLLTACGSSG--PGNSVK
MSMEG_6307|M.smegmatis_MC2_155 --------------------------------MLLAGCGPAANDSDEPIK
Mvan_5107|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2822|M.thermoresistible__bu --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAV_4750|M.avium_104 ----------------------------------------------MAEA
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0714|M.marinum_M --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MAB_4223|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK DSGVLRVGTEGVYAPFSFHDPATGQLTGYDVDVARAVGEKLGVNVEFVET
MSMEG_6307|M.smegmatis_MC2_155 AAGVLRVGTEGVYAPFSYHDPATNELTGYDIDVVKAVADKIGVQIQFVET
Mvan_5107|M.vanbaalenii_PYR-1 ----------------------------MSCPSVAGWRTAAAVLVVLAG-
TH_2822|M.thermoresistible__bu ----------------------------MSISRAALLLTASALTVALN--
MLBr_00303|M.leprae_Br4923 ----MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLPPPTP
MAV_4750|M.avium_104 ERVPMTAGLPLLRRACT---ALAAVLVAAGCGHTESLRVASVPTLPPPTP
Mb0419c|M.bovis_AF2122/97 -----MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTP
Rv0411c|M.tuberculosis_H37Rv -----MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTP
MMAR_0714|M.marinum_M -----MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTP
MUL_2809|M.ulcerans_Agy99 -----MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTP
MAB_4223|M.abscessus_ATCC_1997 -----MTRYAMQGTARRFGALAFVAALLAGCSTPENSTPLPQLTVPRPTP
Mflv_1232|M.gilvum_PYR-GCK PWDSIFAALEANRFDVVANQVTITPERQQKYDLSEPYSIGEGVIVTRADD
MSMEG_6307|M.smegmatis_MC2_155 PWDSIFAALEANRFDIIANEVTITDERKAKYDLSEPYSVGEGVIVTRADD
:
Mvan_5107|M.vanbaalenii_PYR-1 ----------------PACAAPVG---VTAPTLDSSKCSRDVLATQYPGI
TH_2822|M.thermoresistible__bu -----------------ACAAGTDEPTATEPVAEPPACHKEHLPTLEPGV
MLBr_00303|M.leprae_Br4923 VGMEQVPPELL--LPQDNTEEDCDPTASLRPFPTKAEADAAVAEIRARGR
MAV_4750|M.avium_104 VGMEQLPPQPP--LPPDGPDQNCDLTASLRPFPTKAEADAAVADIRARGR
Mb0419c|M.bovis_AF2122/97 VGMEIMPPQPP--LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGR
Rv0411c|M.tuberculosis_H37Rv VGMEIMPPQPP--LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGR
MMAR_0714|M.marinum_M VGMEVMPPEPP--LPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGR
MUL_2809|M.ulcerans_Agy99 VGMEVMPPEPP--LPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGR
MAB_4223|M.abscessus_ATCC_1997 AEMTEQEPNR---AVLDKIDTSCDPTASLRPTSDRAANDEAVAAIRKRGR
Mflv_1232|M.gilvum_PYR-GCK DSITSLDDLRGRRAAQSTTSNWAQVARDAGAQIESVEGLTQAMALLSQGR
MSMEG_6307|M.smegmatis_MC2_155 NSITSLDDLKGKVAAENATSNWSEIARQAGARVEAVEGFTQAIKLLNQGR
. *
Mvan_5107|M.vanbaalenii_PYR-1 LTFGADQPVYPPWYMGDD------------PTNGDGFESALAYALAAKLN
TH_2822|M.thermoresistible__bu LTLATKPIAVNPWYINNQ------------PENGQGYESAVAYAVAEKLG
MLBr_00303|M.leprae_Br4923 LIVGLEIGSNLFSFRDPI------------TGEITGFDIDIAGEVARDIF
MAV_4750|M.avium_104 LIVGLDIGSNLFSFRDPI------------TGEITGFDVDIAGEIARDIF
Mb0419c|M.bovis_AF2122/97 LIVGLDIGSNLFSFRDPI------------TGEITGFDVDIAGEVARDIF
Rv0411c|M.tuberculosis_H37Rv LIVGLDIGSNLFSFRDPI------------TGEITGFDVDIAGEVARDIF
MMAR_0714|M.marinum_M LIVGLDIGSNLFSFRDPI------------TGEITGFDVDIASEVARDIF
MUL_2809|M.ulcerans_Agy99 LIVGLDIGSNLFSFRDPI------------TGEITGFDVDIASEVARDIF
MAB_4223|M.abscessus_ATCC_1997 LVVGLDIGSNLFSFRDPI------------TGELTGFDVDIAGEVSRDIF
Mflv_1232|M.gilvum_PYR-GCK VDVVVNDSLSIYAYLAETGDTAVKIAGTTGEKSEQGFAARKNSGLLPDLN
MSMEG_6307|M.smegmatis_MC2_155 VDVVVNDSIAVYAYLAETGDTSVKIAGEVGEKSEQGFAARKDSGYLPELN
: . . : . *: .:
Mvan_5107|M.vanbaalenii_PYR-1 YTGDDVRWV-------------------------------RVPFNTALAP
TH_2822|M.thermoresistible__bu YNRSEVRWI-------------------------------RTEFTDTIAP
MLBr_00303|M.leprae_Br4923 GTPSHMEYR-------------------------------ILSTAARITA
MAV_4750|M.avium_104 GAPSHVEYR-------------------------------ILSSDERVTA
Mb0419c|M.bovis_AF2122/97 GVPSHVEYR-------------------------------ILSAAERVTA
Rv0411c|M.tuberculosis_H37Rv GVPSHVEYR-------------------------------ILSAAERVTA
MMAR_0714|M.marinum_M GGPTHVEYR-------------------------------ILSAAERITA
MUL_2809|M.ulcerans_Agy99 GGPTHVEYR-------------------------------ILSAAERITA
MAB_4223|M.abscessus_ATCC_1997 GTPERVEYR-------------------------------ILSSADRVAA
Mflv_1232|M.gilvum_PYR-GCK TAVEELKADGTMAEISQKYLKTNASGGQDTPQAQP--RSTLQLVLDNLWP
MSMEG_6307|M.smegmatis_MC2_155 RALDELRADGTLAQISQKYLKADATGAANGDGAPPAVRSTWQLIGDNLWP
:. : .
Mvan_5107|M.vanbaalenii_PYR-1 GAKT-FDVNLSQFSITEQRRAAVDFSTPYFDVTQAVVAVRTSPAAA-VTT
TH_2822|M.thermoresistible__bu GDKP-FDLNLSEVTITEERRQAVDFSSGYYNPTHAFLTTAQSPAAG-ITT
MLBr_00303|M.leprae_Br4923 LQKSEVDIIVKTMTITCKRRKLVNFSTVYLDAKQRILAPRDSP----ITK
MAV_4750|M.avium_104 LQRGEVDVVVKTMTITCDRRKQVNFSTVYLDANQRILAPRDSP----ITK
Mb0419c|M.bovis_AF2122/97 LQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSP----ITK
Rv0411c|M.tuberculosis_H37Rv LQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSP----ITK
MMAR_0714|M.marinum_M LQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDSP----IFK
MUL_2809|M.ulcerans_Agy99 LQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDSP----IFK
MAB_4223|M.abscessus_ATCC_1997 LKNSTVDIVVKTMTITCARRKEVNFSSVYLMNYQRILTSRDSG----ITN
Mflv_1232|M.gilvum_PYR-GCK LAKAALTMTIPLTIISFVIGLVIALGVALARLSSNVVLSNLARFYISVIR
MSMEG_6307|M.smegmatis_MC2_155 LAKAAVTMTIPLTIISFAIGLVIALGVALARLSSNAVLSNVARLYISIIR
. : : *: : :. : : :
Mvan_5107|M.vanbaalenii_PYR-1 LDGLRPLRLGAQVGTTSHTAATELGGSVPVQAYNTNVDAKMALLDGEIDA
TH_2822|M.thermoresistible__bu RDELSGVRLGARTGTTNHQTAVRLSGEYPAIEFATDEEGREALLNGDIDV
MLBr_00303|M.leprae_Br4923 PSDLSNKRVCMTRGTTSLHQVSEVVPPPIIVSAENWADCLVAMQQREIDA
MAV_4750|M.avium_104 VSDLSGKRVCVAKGTTSLHRIRQIDPPPIVVSVVNWADCLVAMQQREIDA
Mb0419c|M.bovis_AF2122/97 VSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
Rv0411c|M.tuberculosis_H37Rv VSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
MMAR_0714|M.marinum_M VSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
MUL_2809|M.ulcerans_Agy99 VSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
MAB_4223|M.abscessus_ATCC_1997 AQDLSGRRVCAARGTTSLNRLSQITPPPVIMSVVTWADCLVALQQRQVDA
Mflv_1232|M.gilvum_PYR-GCK GTPLLVQLFIVFFALPEFGVKIDPFPAAVIAFSLNVGGYAAEIIRSAIQS
MSMEG_6307|M.smegmatis_MC2_155 GTPLLVQLFLVFYALPEFGVRIDPFPAAVIAFSLNVGGYAAEIIRAAILS
* . . .. . : :
Mvan_5107|M.vanbaalenii_PYR-1 MVV---DLPTALTMAEELRHGVLVGQLPADGEHLEQFGIVLSHG-SPLTR
TH_2822|M.thermoresistible__bu LVL---DLRTAFSTQLELPGSVIIGQLEPEPGNSEQYGIVLAKD-SPLTD
MLBr_00303|M.leprae_Br4923 IST---DDAILAGLVEEDPYLHIVGPNMAT----QPYGIGINLNNTTLVR
MAV_4750|M.avium_104 VST---DDSILAGLVEEDPYLHIVGPNMAT----QPYGIGINLNNTGLVR
Mb0419c|M.bovis_AF2122/97 VST---DDTILAGLVEEDPYLHIVGPDMAD----QPYGVGINLDNTGLVR
Rv0411c|M.tuberculosis_H37Rv VST---DDTILAGLVEEDPYLHIVGPDMAD----QPYGVGINLDNTGLVR
MMAR_0714|M.marinum_M VST---DDTILAGLVEEDPYLHIVGPNMAN----QPYGIGINLDNTGLVR
MUL_2809|M.ulcerans_Agy99 VST---DDTILAGLVEEDPYLHIVGPNMAN----QPYGIGINLDNTGLVR
MAB_4223|M.abscessus_ATCC_1997 VST---DDSILAGLMSQDPYLHIIGPNMSD----EPYGIGIKLENTDLVR
Mflv_1232|M.gilvum_PYR-GCK IPKGQWEAAETIGLNYVGTLRRIILPQATRVAVPPLSNTLISLVKDTSLA
MSMEG_6307|M.smegmatis_MC2_155 IPKGQWEAAETIGLTYGKSLQRIILPQAARVAVPPLSNTLISLVKDTSLA
: : :: . . :
Mvan_5107|M.vanbaalenii_PYR-1 CVSWAVDSLREDGTLAGLQNRWLTDTGPVAVLR-----------------
TH_2822|M.thermoresistible__bu CVSQAVDELGDNGDLFRLQKEWLAGPGAAPFLP-----------------
MLBr_00303|M.leprae_Br4923 FVNGTLERIRRDGTWITLYRKWLTVLGPAPAPPTPRYVD-----------
MAV_4750|M.avium_104 FVNGTLERIRRDGTWNTLYRKWLTVLGPAPAPPTPRYLD-----------
Mb0419c|M.bovis_AF2122/97 FVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD-----------
Rv0411c|M.tuberculosis_H37Rv FVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD-----------
MMAR_0714|M.marinum_M FVNGTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD-----------
MUL_2809|M.ulcerans_Agy99 FVNGTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD-----------
MAB_4223|M.abscessus_ATCC_1997 YVNRTLERIRRDGTWNALYRKWLSVLGPAPAPPSAKYRD-----------
Mflv_1232|M.gilvum_PYR-GCK STILVTELLRQAQIIAAPTFEFFALYGTAAVYYWVICLVLSFGQARFEHR
MSMEG_6307|M.smegmatis_MC2_155 STILVTELLRQAQIAAAPTFEFFALYGTAAVYYWVICLVLSFGQSRIERR
. . : : .::: *...
Mvan_5107|M.vanbaalenii_PYR-1 -------
TH_2822|M.thermoresistible__bu -------
MLBr_00303|M.leprae_Br4923 -------
MAV_4750|M.avium_104 -------
Mb0419c|M.bovis_AF2122/97 -------
Rv0411c|M.tuberculosis_H37Rv -------
MMAR_0714|M.marinum_M -------
MUL_2809|M.ulcerans_Agy99 -------
MAB_4223|M.abscessus_ATCC_1997 -------
Mflv_1232|M.gilvum_PYR-GCK LERYVAR
MSMEG_6307|M.smegmatis_MC2_155 LERYVAR