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VTGPSNPLRLACLDAEAPPLFSLWTPENGRQGYEPGVAEVLGAELGRPIEWVRVPWVDMIPAVQRGDADA VLCGQGITAERQAQVDFTRPYAIFHEGVLVRRGSGIHAPEDLVGRKVAAIENSTNMALAQTFTGAEPIAF GAGSDDVYADMLAALLAGEVDAVVDDDVVFVPLGATHPDYELAFTVQTGNRWGIAVAKDRPDTLAEIDGA LGRLIESGRLRKVWEEWLPTLDYPFAGD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1851 | - | - | 100% (238) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_0704 | - | 1e-15 | 27.31% (216) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_5576 | - | 2e-14 | 30.74% (231) | polar amino acid ABC transporter, inner membrane subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 6e-13 | 25.46% (216) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_1232 | - | 6e-15 | 30.30% (231) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0411c | glnH | 6e-13 | 25.46% (216) | glutamine-binding lipoprotein |
| M. leprae Br4923 | MLBr_00303 | glnH | 1e-11 | 25.00% (216) | putative glutamine-binding protein |
| M. abscessus ATCC 19977 | MAB_0277c | - | 1e-17 | 31.00% (229) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0714 | glnH | 4e-13 | 25.46% (216) | glutamine-binding lipoprotein GlnH |
| M. avium 104 | MAV_4750 | - | 2e-13 | 25.46% (216) | extracellular solute-binding protein, family protein 3 |
| M. smegmatis MC2 155 | MSMEG_6692 | - | 1e-121 | 90.39% (229) | putative glutamine-binding periplasmic protein |
| M. thermoresistible (build 8) | TH_2308 | glnH | 8e-18 | 27.31% (216) | PROBABLE GLUTAMINE-BINDING LIPOPROTEIN GLNH (GLNBP) |
| M. ulcerans Agy99 | MUL_2809 | glnH | 3e-13 | 25.46% (216) | glutamine-binding lipoprotein GlnH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0419c|M.bovis_AF2122/97 ---------MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLP
Rv0411c|M.tuberculosis_H37Rv ---------MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLP
MMAR_0714|M.marinum_M ---------MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLP
MUL_2809|M.ulcerans_Agy99 ---------MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLP
MLBr_00303|M.leprae_Br4923 --------MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLP
MAV_4750|M.avium_104 MAEAERVPMTAGLPLLRRACT---ALAAVLVAAGCGHTESLRVASVPTLP
TH_2308|M.thermoresistible__bu ------MDIEVRTMGTPVKRLVAVLGVLGMLLTGCGESNSVAPAPEVVLN
Mvan_1851|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6692|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 LPTPVGMEIMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRAR
Rv0411c|M.tuberculosis_H37Rv LPTPVGMEIMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRAR
MMAR_0714|M.marinum_M LPTPVGMEVMPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRAR
MUL_2809|M.ulcerans_Agy99 LPTPVGMEVMPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRAR
MLBr_00303|M.leprae_Br4923 PPTPVGMEQVPPELLLPQDNTEEDCDPTASLRPFPTKAEADAAVAEIRAR
MAV_4750|M.avium_104 PPTPVGMEQLPPQPPLPPDGPDQNCDLTASLRPFPTKAEADAAVADIRAR
TH_2308|M.thermoresistible__bu PPSPSGMEEMPPQPAQMPDPKAEDCDRTASLRPFPTRAEADEAVAHIRER
Mvan_1851|M.vanbaalenii_PYR-1 -----------------------MTGPSN--PLRLACLDAEAP-------
MSMEG_6692|M.smegmatis_MC2_155 -----------------------MTETTTRAPLRLACLDAEAP-------
Mflv_1232|M.gilvum_PYR-GCK MSRTLGRTRRACYGPPMGNPRRVLLAVLAALAVLLTACGSSGPGNSVKDS
MAB_0277c|M.abscessus_ATCC_199 ------------------MFRAIVLALLALVAVAGCAAPTQEP-------
:. .
Mb0419c|M.bovis_AF2122/97 GRLIVGLDIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRI
Rv0411c|M.tuberculosis_H37Rv GRLIVGLDIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRI
MMAR_0714|M.marinum_M GRLIVGLDIGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRI
MUL_2809|M.ulcerans_Agy99 GRLIVGLDIGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRI
MLBr_00303|M.leprae_Br4923 GRLIVGLEIGSNLFSFRDPITGEITGFDIDIAGEVARDIFGTPSHMEYRI
MAV_4750|M.avium_104 GRLIVGLDIGSNLFSFRDPITGEITGFDVDIAGEIARDIFGAPSHVEYRI
TH_2308|M.thermoresistible__bu GRLIVGLDIGSNLFSFRDPITGQIAGFDVDIAGEIARDIFGSPAQVEYRI
Mvan_1851|M.vanbaalenii_PYR-1 -----------PLFSLWTPENGRQ-GYEPGVAEVLGAELG---RPIEWVR
MSMEG_6692|M.smegmatis_MC2_155 -----------PLFSLWTPENGRT-GYEPGVAEALGAELG---RPVEWVR
Mflv_1232|M.gilvum_PYR-GCK GVLRVGTEGVYAPFSFHDPATGQLTGYDVDVARAVGEKLG---VNVEFVE
MAB_0277c|M.abscessus_ATCC_199 --LRVGTEGVYAPFSFHDGHTGELTGYDVDVARAVGEKLG---RPVEFVE
**: .*. *:: .:* :. .: :*:
Mb0419c|M.bovis_AF2122/97 LSAAERVTALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRD
Rv0411c|M.tuberculosis_H37Rv LSAAERVTALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRD
MMAR_0714|M.marinum_M LSAAERITALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRD
MUL_2809|M.ulcerans_Agy99 LSAAERITALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRD
MLBr_00303|M.leprae_Br4923 LSTAARITALQKSEVDIIVKTMTITCKRRKLVNFSTVYLDAKQRILAPRD
MAV_4750|M.avium_104 LSSDERVTALQRGEVDVVVKTMTITCDRRKQVNFSTVYLDANQRILAPRD
TH_2308|M.thermoresistible__bu LSSADRIEALQNNEVDVVVKTMTITCERKEKIHFSTAYLNANQRILAPRS
Mvan_1851|M.vanbaalenii_PYR-1 VPWVDMIPAVQRGDADAVLCGQGITAERQAQVDFTRPYAIFHEGVLVRRG
MSMEG_6692|M.smegmatis_MC2_155 VPWVDMIPAVQRGDADAVLCGQGITPERQAQVDFTRPYAIFHEGVLIRRG
Mflv_1232|M.gilvum_PYR-GCK TPWDSIFAALEANRFDVVANQVTITPERQQKYDLSEPYSIG-EGVIVTRA
MAB_0277c|M.abscessus_ATCC_199 IPWDAIFAGLDAERFDVVANQVTITPARKAKYDISTPYAVG-EGVIVTRA
. . .:: * : ** *: .:: * : :: *
Mb0419c|M.bovis_AF2122/97 S--PITKVSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVN----WADC
Rv0411c|M.tuberculosis_H37Rv S--PITKVSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVN----WADC
MMAR_0714|M.marinum_M S--PIFKVSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVN----WADC
MUL_2809|M.ulcerans_Agy99 S--PIFKVSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVN----WADC
MLBr_00303|M.leprae_Br4923 S--PITKPSDLSNKRVCMTRGTTSLHQVSEVVPPPIIVSAEN----WADC
MAV_4750|M.avium_104 S--PITKVSDLSGKRVCVAKGTTSLHRIRQIDPPPIVVSVVN----WADC
TH_2308|M.thermoresistible__bu S--PITRAADLSGRRVCVVKGTTSLTRVQQISPPPIIVAVET----WADC
Mvan_1851|M.vanbaalenii_PYR-1 S--GIHAPEDLVGRKVAAIENSTNMALAQTFTGAEPIAFGAGSDDVYADM
MSMEG_6692|M.smegmatis_MC2_155 T--GIKSPEDLVGRKVAAIENSTNMKLAETFTGAIPVPFGAGSDDVYADM
Mflv_1232|M.gilvum_PYR-GCK DDDSITSLDDLRG-RRAAQSTTSNWAQVARDAGAQIESVEG-----LTQA
MAB_0277c|M.abscessus_ATCC_199 DDNSIHSLSDVRG-KVAAENATSNWSQIARDAGARVEAVEG-----FTQS
* *: . : . ::. . ::
Mb0419c|M.bovis_AF2122/97 LVALQQREIDAVSTDDTILAGLVEEDPYLHIVGPDMADQPYGVGINLDN-
Rv0411c|M.tuberculosis_H37Rv LVALQQREIDAVSTDDTILAGLVEEDPYLHIVGPDMADQPYGVGINLDN-
MMAR_0714|M.marinum_M LVALQQREIDAVSTDDTILAGLVEEDPYLHIVGPNMANQPYGIGINLDN-
MUL_2809|M.ulcerans_Agy99 LVALQQREIDAVSTDDTILAGLVEEDPYLHIVGPNMANQPYGIGINLDN-
MLBr_00303|M.leprae_Br4923 LVAMQQREIDAISTDDAILAGLVEEDPYLHIVGPNMATQPYGIGINLNN-
MAV_4750|M.avium_104 LVAMQQREIDAVSTDDSILAGLVEEDPYLHIVGPNMATQPYGIGINLNN-
TH_2308|M.thermoresistible__bu LVAIQQNQVDAVSTDDSILAGLMAQDPYLHIVGPSMSQEPYGIGINKNN-
Mvan_1851|M.vanbaalenii_PYR-1 LAALLAGEVDAVVDDDVVFVPLGATHPDYELAFTVQTGNRWGIAVAKDR-
MSMEG_6692|M.smegmatis_MC2_155 LAALLAEEVDAVVDDDVVFVPLGATHPDYELAFTVKTANKWGIAVSKDR-
Mflv_1232|M.gilvum_PYR-GCK MALLSQGRVDVVVNDSLSIYAYLAETGDTAVKIAGTTGEKSEQGFAARKN
MAB_0277c|M.abscessus_ATCC_199 ITLLSQGRVDVVINDSIAVYAYLASTGDPAVKIAGATGQRSEQGFAARKN
:. : .:*.: *. . : . : : .. .
Mb0419c|M.bovis_AF2122/97 TGLVRFVNGTLERIRNDGTWNTLYRKWLTVLG------------------
Rv0411c|M.tuberculosis_H37Rv TGLVRFVNGTLERIRNDGTWNTLYRKWLTVLG------------------
MMAR_0714|M.marinum_M TGLVRFVNGTLERIRNDGTWNTLYRKWLSVLG------------------
MUL_2809|M.ulcerans_Agy99 TGLVRFVNGTLERIRNDGTWNTLYRKWLSVLG------------------
MLBr_00303|M.leprae_Br4923 TTLVRFVNGTLERIRRDGTWITLYRKWLTVLG------------------
MAV_4750|M.avium_104 TGLVRFVNGTLERIRRDGTWNTLYRKWLTVLG------------------
TH_2308|M.thermoresistible__bu PGLVRFVNGTLERIRRDGTWNTLYRKWLTVLG------------------
Mvan_1851|M.vanbaalenii_PYR-1 PDTLAEIDGALGRLIESGRLRKVWEEWLPT--------------------
MSMEG_6692|M.smegmatis_MC2_155 PDTLAEIDGALERLISSGRLRDVWKEWLPT--------------------
Mflv_1232|M.gilvum_PYR-GCK SGLLPDLNTAVEELKADGTMAEISQKYLKTNASGGQDTPQAQ------PR
MAB_0277c|M.abscessus_ATCC_199 SGLLPDLDKALDQLAADGTLTRISQKYLKTDASG-TTKPQAGKGDSGSTR
. : :: :: .: .* : .::* .
Mb0419c|M.bovis_AF2122/97 ------PAPAPPTPRYVD--------------------------------
Rv0411c|M.tuberculosis_H37Rv ------PAPAPPTPRYVD--------------------------------
MMAR_0714|M.marinum_M ------PAPAPPRPRYVD--------------------------------
MUL_2809|M.ulcerans_Agy99 ------PAPAPPRPRYVD--------------------------------
MLBr_00303|M.leprae_Br4923 ------PAPAPPTPRYVD--------------------------------
MAV_4750|M.avium_104 ------PAPAPPTPRYLD--------------------------------
TH_2308|M.thermoresistible__bu ------PAPAPPVARYVD--------------------------------
Mvan_1851|M.vanbaalenii_PYR-1 ------LD--YPFAGD----------------------------------
MSMEG_6692|M.smegmatis_MC2_155 ------LD--YPFGE-----------------------------------
Mflv_1232|M.gilvum_PYR-GCK STLQLVLDNLWPLAKAALTMTIPLTIISFVIGLVIALGVALARLSSNVVL
MAB_0277c|M.abscessus_ATCC_199 SDTQLVLDNLWPMARAMITVTLPLTAISFVIGLVIALGVALARMSGHRVV
*
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0714|M.marinum_M --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAV_4750|M.avium_104 --------------------------------------------------
TH_2308|M.thermoresistible__bu --------------------------------------------------
Mvan_1851|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6692|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK SNLARFYISVIRGTPLLVQLFIVFFALPEFGVKIDPFPAAVIAFSLNVGG
MAB_0277c|M.abscessus_ATCC_199 TGLARIYISVIRGTPLLLQLFLIFFALPEFGVKISPFPAAVIAFSLNVGG
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0714|M.marinum_M --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAV_4750|M.avium_104 --------------------------------------------------
TH_2308|M.thermoresistible__bu --------------------------------------------------
Mvan_1851|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6692|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK YAAEIIRSAIQSIPKGQWEAAETIGLNYVGTLRRIILPQATRVAVPPLSN
MAB_0277c|M.abscessus_ATCC_199 YAAEIIRSSILSIPRGQWEAASSLGMSYSTTLWRIVIPQASRVAVPPLSN
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0714|M.marinum_M --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAV_4750|M.avium_104 --------------------------------------------------
TH_2308|M.thermoresistible__bu --------------------------------------------------
Mvan_1851|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6692|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1232|M.gilvum_PYR-GCK TLISLVKDTSLASTILVTELLRQAQIIAAPTFEFFALYGTAAVYYWVICL
MAB_0277c|M.abscessus_ATCC_199 TLISLVKDTSLASAILVTDVMRTAQVAAAPTFQFFTLYVTAGVYYWIVCM
Mb0419c|M.bovis_AF2122/97 -------------------
Rv0411c|M.tuberculosis_H37Rv -------------------
MMAR_0714|M.marinum_M -------------------
MUL_2809|M.ulcerans_Agy99 -------------------
MLBr_00303|M.leprae_Br4923 -------------------
MAV_4750|M.avium_104 -------------------
TH_2308|M.thermoresistible__bu -------------------
Mvan_1851|M.vanbaalenii_PYR-1 -------------------
MSMEG_6692|M.smegmatis_MC2_155 -------------------
Mflv_1232|M.gilvum_PYR-GCK VLSFGQARFEHRLERYVAR
MAB_0277c|M.abscessus_ATCC_199 AMSAVQDRLEQRLEKSVAR