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PDSSAPDVAVTARAITMRGPWGPVYGPVDLDIAAGGVTVLVCPPGSGRTALLMTLAGRMRPASGSLSVFG RTRVHDIFAHAALAGIDELDTVAESVTVRDLITEQLRWDADWYKLIRRAGEDDVARVCGPVFGDLPLPPL SEYVEELTELDGLLLRIALANTGRPPLLVVGNLEQVTSDPERDLLVSRLVELGREQTVVTAGVNGVSDHP VVQIEVENTTRAELANQQKGGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4996 | - | - | 100% (233) | hypothetical protein Mvan_4996 |
| M. vanbaalenii PYR-1 | Mvan_3091 | - | 2e-06 | 41.18% (68) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2047 | - | 2e-06 | 36.46% (96) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3067c | - | 2e-07 | 30.19% (106) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_1751 | - | 4e-76 | 60.94% (233) | hypothetical protein Mflv_1751 |
| M. tuberculosis H37Rv | Rv3041c | - | 2e-07 | 30.19% (106) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01892 | - | 1e-06 | 28.23% (124) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4761 | - | 6e-30 | 36.59% (205) | hypothetical protein MAB_4761 |
| M. marinum M | MMAR_1660 | - | 1e-06 | 28.30% (106) | ABC transporter ATP-binding protein |
| M. avium 104 | MAV_1612 | - | 2e-32 | 38.54% (205) | hypothetical protein MAV_1612 |
| M. smegmatis MC2 155 | MSMEG_5645 | - | 4e-83 | 65.67% (233) | hypothetical protein MSMEG_5645 |
| M. thermoresistible (build 8) | TH_0089 | - | 2e-88 | 70.93% (227) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1897 | - | 9e-07 | 28.30% (106) | ABC transporter ATP-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3067c|M.bovis_AF2122/97 MRHDSRVLDN----GGPD--------------AADPDLLIDFRNVSLRRN
Rv3041c|M.tuberculosis_H37Rv MRHDSRVLDN----GGPD--------------AADPDLLIDFRNVSLRRN
MMAR_1660|M.marinum_M -------MSE----AGPD--------------TADPDLLIDFRDVSLRRG
MUL_1897|M.ulcerans_Agy99 -------MSE----AGPD--------------TADPDLLIDFRDVSLRRG
Mvan_4996|M.vanbaalenii_PYR-1 -------MP-----DSS-----------------APDVAVTARAITMRGP
TH_0089|M.thermoresistible__bu -------MP-----DQPEP-------------EQAPEPALTARGICMRGP
MSMEG_5645|M.smegmatis_MC2_155 -------MPQLTAEPDPDA-------------DEQKPPAITAREITMRGP
Mflv_1751|M.gilvum_PYR-GCK -------MS-----DAP-----------------AAELAITARALTLNGP
MAB_4761|M.abscessus_ATCC_1997 -------MNAQ---DEPATTPDETDIAISKETNDQAPVLITATGLGVDGE
MAV_1612|M.avium_104 -------MDAN---NEP---------------DDVAPV-ITAAGLGVDGE
MLBr_01892|M.leprae_Br4923 ---------------------------------MPMGVAIEVKGLTKSFG
: :
Mb3067c|M.bovis_AF2122/97 GRTLVGPLDWAVELDERWVIVGPNGAGKTSLLRIAAAAEHPSSGVAFVLG
Rv3041c|M.tuberculosis_H37Rv GRTLVGPLDWAVELDERWVIVGPNGAGKTSLLRIAAAAEHPSSGVAFVLG
MMAR_1660|M.marinum_M GRTLVGPLDWAVELDERWVILGPNGAGKTSLLRMAAASEHPSSGVAFVLG
MUL_1897|M.ulcerans_Agy99 GRTLVGPLDWAVELDERWVILGPNGAGKTSLLRMAAASEHPSSGVAFVLG
Mvan_4996|M.vanbaalenii_PYR-1 WGPVYGPVDLDIAAGGVTVLVCPPGSGRTALLMTLAGRMRPASGSLSVFG
TH_0089|M.thermoresistible__bu WGPVYGPIDLDIEAGGVTVLHCPPGSGRTALLMTLAGRMRPMSGELTVFG
MSMEG_5645|M.smegmatis_MC2_155 FGPVYGPVDLDIAEGGVTALVAPSGAGRTALLLTLAGRMKPQSGEVTVLG
Mflv_1751|M.gilvum_PYR-GCK AGPLYGPVDLDVDEGGVTVLVCPPGVGRTALLLTLAGRMRPTSGRLSVLG
MAB_4761|M.abscessus_ATCC_1997 HGPLFSGIGLELTSG-FHAIQMPGGPAQHCLLLTLAGRLKASHGTVNVMG
MAV_1612|M.avium_104 HGPLFSGVDLALTPG-FHAIQMPGGPGQTTLLLTLAGRFKPSHGTLTVLG
MLBr_01892|M.leprae_Br4923 SSRIWEDVTLDIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSILIDG
: : : . .: * * .: :* . :. * : *
Mb3067c|M.bovis_AF2122/97 ERLGRVDVSELRARVGLSSSALAE-RVPGDERVRDLVVSAGYAVLGRWRE
Rv3041c|M.tuberculosis_H37Rv ERLGRVDVSELRARVGLSSSALAE-RVPGDERVRDLVVSAGYAVLGRWRE
MMAR_1660|M.marinum_M ERLGRVDVSELRARIGLSSSALAQ-RIPTDEVVRDLVVSAGYAVLGRWRE
MUL_1897|M.ulcerans_Agy99 ERLGRVDVSELRARIGLSSSALAQ-RIPTDEVVRDLVVSAGYAVLGRWRE
Mvan_4996|M.vanbaalenii_PYR-1 R----TRVHDIFAHAALAGIDELD-TVAESVTVRDLITEQ-----LRW--
TH_0089|M.thermoresistible__bu R----TRAPDIFRVAGLAGFDEVD-PIPQSVTVRDLVTEQ-----VRW--
MSMEG_5645|M.smegmatis_MC2_155 R----TRAKDIFDISAVAAVEDID-AVPESVTVADVITEQ-----RRW--
Mflv_1751|M.gilvum_PYR-GCK R----TGARSIFGIAAVAAVDGVD-DVAQTATVGELVTEK-----MRW--
MAB_4761|M.abscessus_ATCC_1997 D----TEPRAIRRHCAIAAFADID-ELEETVTVQTVLAEQ-----RRW--
MAV_1612|M.avium_104 E----TTPRAIRRHCSIAAFEGID-DLEDSVTVGTVLAEQ-----RRW--
MLBr_01892|M.leprae_Br4923 TDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKES
: : . : : : . :
Mb3067c|M.bovis_AF2122/97 RYEAVDYHRAIDMLESLGAEHLANRTYGTLSEGERKRVLIARALMTDPEL
Rv3041c|M.tuberculosis_H37Rv RYEAVDYHRAIDMLESLGAEHLANRTYGTLSEGERKRVLIARALMTDPEL
MMAR_1660|M.marinum_M RYEDVDYRRAVDMLESLGAEHLADRTYGTLSEGERKRVLIARALMTDPEL
MUL_1897|M.ulcerans_Agy99 RYEDVDYRRAVDMLESLGAEHLADRTYGTLSEGERKRVLIARALMTDPEL
Mvan_4996|M.vanbaalenii_PYR-1 ---DADWYKLIRRAGEDDVARVCGPVFGDLPL------------------
TH_0089|M.thermoresistible__bu ---DAPWYRLIPRAGEAELAAVCGPVFGELPL------------------
MSMEG_5645|M.smegmatis_MC2_155 ---DAPWYRRVPRAGADDLAALCGPVFGDLPL------------------
Mflv_1751|M.gilvum_PYR-GCK ---DAPWYRAIRRADDAEVAGFCGPVFGDLPI------------------
MAB_4761|M.abscessus_ATCC_1997 ---LAPWFSRVPADTG---RDKLDEVFGELPP------------------
MAV_1612|M.avium_104 ---LAPWYSSVPLQSG---PAELTEVFGDMAP------------------
MLBr_01892|M.leprae_Br4923 EIRDIVMEKLQLVGLGGDEKKFPGEISGGMRKRAG----LARALVLDPQI
* :
Mb3067c|M.bovis_AF2122/97 LLLDEPAAGLDLGGREELVARLADLAADPDAPALVLVTHH-VEEIPPGFS
Rv3041c|M.tuberculosis_H37Rv LLLDEPAAGLDLGGREELVARLADLAADPDAPALVLVTHH-VEEIPPGFS
MMAR_1660|M.marinum_M LLLDEPAAGLDLGGREELVARLADLAADPDAPALVLVTHH-VEEVPPGFS
MUL_1897|M.ulcerans_Agy99 LLLDEPAAGLDLGGREELVARLADLAADPDAPALVLVTHH-VEEVPPGFS
Mvan_4996|M.vanbaalenii_PYR-1 -----PPLSEYVEELTELDGLLLRIALANTGRPPLLVVGN-LEQVTSDPE
TH_0089|M.thermoresistible__bu -----PPLGEYVGELSELDRMLLRIALANTRRPALLVAGN-LDDVAADHS
MSMEG_5645|M.smegmatis_MC2_155 -----PPLGEYFDELTELDRVLLRIALANTSRPPLLVVGD-FDHVTDDRN
Mflv_1751|M.gilvum_PYR-GCK -----PAATAPVEELGELDAMLLLIALANSVRPALLVVGG-IDRVAEDGS
MAB_4761|M.abscessus_ATCC_1997 -----PSGETFIVELSDLDLFLLRITLALLSDRPILVVGD-LEQVRDNAR
MAV_1612|M.avium_104 -----PSDNTYVVELSDLELFLLRITLALLSNRPILVVGD-LEQVRDNSR
MLBr_01892|M.leprae_Br4923 ILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNM
* * : : ::. . .
Mb3067c|M.bovis_AF2122/97 HCLLLSEARVVAAG------------------------------------
Rv3041c|M.tuberculosis_H37Rv HCLLLSEARVVAAG------------------------------------
MMAR_1660|M.marinum_M HCLLLAEGHVVASG------------------------------------
MUL_1897|M.ulcerans_Agy99 HCLLLAEGHVVASG------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 RDLLVSRLVELGR-------------------------------------
TH_0089|M.thermoresistible__bu RDQLVRRLIALGE-------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 RELLAERLIALGE-------------------------------------
Mflv_1751|M.gilvum_PYR-GCK RDLLVQRLAALGD-------------------------------------
MAB_4761|M.abscessus_ATCC_1997 RTLAVERLGVIAQ-------------------------------------
MAV_1612|M.avium_104 RAIAAERLGAIAR-------------------------------------
MLBr_01892|M.leprae_Br4923 GMLFRKHLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAE
. ..
Mb3067c|M.bovis_AF2122/97 ---LLPDALTAENLSTAFGQEITLEVADGRYFARRRRSRAAHRRQS----
Rv3041c|M.tuberculosis_H37Rv ---LLPDALTAENLSTAFGQEITLEVADGRYFARRRRSRAAHRRQS----
MMAR_1660|M.marinum_M ---LLSDVLTAENLSAAFGQQIAVDFVDGRYFARRIRARAAHRRQQ----
MUL_1897|M.ulcerans_Agy99 ---LLSDVLTAENLWAAFGQQIAVDFVDGRYFARRIRARAAHRRQQ----
Mvan_4996|M.vanbaalenii_PYR-1 -----EQTVVTAGVNGVSDHPV-VQIEVENTTRAELANQQKGGA------
TH_0089|M.thermoresistible__bu -----RQTVITATVNEVVGHDVRARIPVPNTSRAELAHRQKGDQ------
MSMEG_5645|M.smegmatis_MC2_155 -----QQTVVTATVNPVSNPAV-THIAVPNTTPAELASAQKGEK------
Mflv_1751|M.gilvum_PYR-GCK -----RQTIVTAGANGVSGHAV-RQIVVGTITRPEWAGDPGGVA------
MAB_4761|M.abscessus_ATCC_1997 -----NRTVVVGVTNPLGTDAPVHDLHDHRILTGRD--------------
MAV_1612|M.avium_104 -----QRTVVVGVTNPLGADAPDHELHDHRIPTGED--------------
MLBr_01892|M.leprae_Br4923 EAALLEAGHYAGGAEEVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTL
. .
Mb3067c|M.bovis_AF2122/97 -------------------------
Rv3041c|M.tuberculosis_H37Rv -------------------------
MMAR_1660|M.marinum_M -------------------------
MUL_1897|M.ulcerans_Agy99 -------------------------
Mvan_4996|M.vanbaalenii_PYR-1 -------------------------
TH_0089|M.thermoresistible__bu -------------------------
MSMEG_5645|M.smegmatis_MC2_155 -------------------------
Mflv_1751|M.gilvum_PYR-GCK -------------------------
MAB_4761|M.abscessus_ATCC_1997 -------------------------
MAV_1612|M.avium_104 -------------------------
MLBr_01892|M.leprae_Br4923 PKGAQAAILDDLEGAHNYQAHEFGD