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PQLTAEPDPDADEQKPPAITAREITMRGPFGPVYGPVDLDIAEGGVTALVAPSGAGRTALLLTLAGRMKP QSGEVTVLGRTRAKDIFDISAVAAVEDIDAVPESVTVADVITEQRRWDAPWYRRVPRAGADDLAALCGPV FGDLPLPPLGEYFDELTELDRVLLRIALANTSRPPLLVVGDFDHVTDDRNRELLAERLIALGEQQTVVTA TVNPVSNPAVTHIAVPNTTPAELASAQKGEK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5645 | - | - | 100% (242) | hypothetical protein MSMEG_5645 |
| M. smegmatis MC2 155 | MSMEG_6553 | - | 5e-08 | 27.40% (208) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6911 | - | 4e-07 | 37.50% (72) | ABC transporter, ATP-binding protein GluA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-06 | 45.45% (44) | sulfate-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_1751 | - | 2e-68 | 58.11% (222) | hypothetical protein Mflv_1751 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-06 | 45.45% (44) | sulfate-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01892 | - | 4e-06 | 29.27% (82) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4761 | - | 8e-39 | 43.72% (215) | hypothetical protein MAB_4761 |
| M. marinum M | MMAR_3715 | cysA1 | 4e-07 | 27.84% (176) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1612 | - | 1e-40 | 44.95% (218) | hypothetical protein MAV_1612 |
| M. thermoresistible (build 8) | TH_0089 | - | 1e-84 | 64.98% (237) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-08 | 28.41% (176) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_4996 | - | 4e-83 | 65.67% (233) | hypothetical protein Mvan_4996 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0089|M.thermoresistible__bu ------MP-----DQPEP-------------EQAPEPALTARGICMRGPW
Mvan_4996|M.vanbaalenii_PYR-1 ------MP-----DSS-----------------APDVAVTARAITMRGPW
MSMEG_5645|M.smegmatis_MC2_155 ------MPQLTAEPDPDA-------------DEQKPPAITAREITMRGPF
Mflv_1751|M.gilvum_PYR-GCK ------MS-----DAP-----------------AAELAITARALTLNGPA
MAB_4761|M.abscessus_ATCC_1997 ------MNAQ---DEPATTPDETDIAISKETNDQAPVLITATGLGVDGEH
MAV_1612|M.avium_104 ------MDAN---NEP---------------DDVAPV-ITAAGLGVDGEH
Mb2419c|M.bovis_AF2122/97 ------MT---------------------------YAIVVADATKRYGDF
Rv2397c|M.tuberculosis_H37Rv ------MT---------------------------YAIVVADATKRYGDF
MMAR_3715|M.marinum_M MKKETSLTGPGT---------------------GGHAIVVRDAFKQYGDF
MUL_3658|M.ulcerans_Agy99 ------MTGPGT---------------------GGHAIVVRDAFKQYGDF
MLBr_01892|M.leprae_Br4923 ------MP--------------------------MGVAIEVKGLTKSFGS
: :
TH_0089|M.thermoresistible__bu GPVYGPIDLDIEAGGVTVLHCPPGSGRTALLMTLAGRMRPMSGELTVFG-
Mvan_4996|M.vanbaalenii_PYR-1 GPVYGPVDLDIAAGGVTVLVCPPGSGRTALLMTLAGRMRPASGSLSVFG-
MSMEG_5645|M.smegmatis_MC2_155 GPVYGPVDLDIAEGGVTALVAPSGAGRTALLLTLAGRMKPQSGEVTVLG-
Mflv_1751|M.gilvum_PYR-GCK GPLYGPVDLDVDEGGVTVLVCPPGVGRTALLLTLAGRMRPTSGRLSVLG-
MAB_4761|M.abscessus_ATCC_1997 GPLFSGIGLELTSG-FHAIQMPGGPAQHCLLLTLAGRLKASHGTVNVMG-
MAV_1612|M.avium_104 GPLFSGVDLALTPG-FHAIQMPGGPGQTTLLLTLAGRFKPSHGTLTVLG-
Mb2419c|M.bovis_AF2122/97 VALD-HVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGR
Rv2397c|M.tuberculosis_H37Rv VALD-HVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGR
MMAR_3715|M.marinum_M VALD-HVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGR
MUL_3658|M.ulcerans_Agy99 VALD-HVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSGNITINGR
MLBr_01892|M.leprae_Br4923 SRIWEDVTLDIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSILIDGT
: : : : * . .: * * .: :* :: * :. * : : *
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1612|M.avium_104 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFG------LKIRKRPKAE
Rv2397c|M.tuberculosis_H37Rv DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFG------LKIRKRPKAE
MMAR_3715|M.marinum_M DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYG------LKIRKRPKAE
MUL_3658|M.ulcerans_Agy99 DVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYG------LKIRKRPKAE
MLBr_01892|M.leprae_Br4923 DIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESE
TH_0089|M.thermoresistible__bu -RTRAPDIFRVAGLAGFDE-------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 -RTRVHDIFAHAALAGIDE-------------------------------
MSMEG_5645|M.smegmatis_MC2_155 -RTRAKDIFDISAVAAVED-------------------------------
Mflv_1751|M.gilvum_PYR-GCK -RTGARSIFGIAAVAAVDG-------------------------------
MAB_4761|M.abscessus_ATCC_1997 -DTEPRAIRRHCAIAAFAD-------------------------------
MAV_1612|M.avium_104 -ETTPRAIRRHCSIAAFEG-------------------------------
Mb2419c|M.bovis_AF2122/97 IKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
Rv2397c|M.tuberculosis_H37Rv IKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
MMAR_3715|M.marinum_M IRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVLLLDE
MUL_3658|M.ulcerans_Agy99 IRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDE
MLBr_01892|M.leprae_Br4923 IRDIVMEKLQLVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDE
.:..
TH_0089|M.thermoresistible__bu ----------------VDPIPQSVTVRDLVTEQVRWDAPWYR---LIPRA
Mvan_4996|M.vanbaalenii_PYR-1 ----------------LDTVAESVTVRDLITEQLRWDADWYK---LIRRA
MSMEG_5645|M.smegmatis_MC2_155 ----------------IDAVPESVTVADVITEQRRWDAPWYR---RVPRA
Mflv_1751|M.gilvum_PYR-GCK ----------------VDDVAQTATVGELVTEKMRWDAPWYR---AIRRA
MAB_4761|M.abscessus_ATCC_1997 ----------------IDELEETVTVQTVLAEQRRWLAPWFS---RVPAD
MAV_1612|M.avium_104 ----------------IDDLEDSVTVGTVLAEQRRWLAPWYS---SVPLQ
Mb2419c|M.bovis_AF2122/97 PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
Rv2397c|M.tuberculosis_H37Rv PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
MMAR_3715|M.marinum_M PFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNS
MUL_3658|M.ulcerans_Agy99 PFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNS
MLBr_01892|M.leprae_Br4923 PDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFR
: : . ::. : * :
TH_0089|M.thermoresistible__bu GEAELAAVCGPVFGELPLPPLGEYVG--ELSELDRMLLRIALANTRRPAL
Mvan_4996|M.vanbaalenii_PYR-1 GEDDVARVCGPVFGDLPLPPLSEYVE--ELTELDGLLLRIALANTGRPPL
MSMEG_5645|M.smegmatis_MC2_155 GADDLAALCGPVFGDLPLPPLGEYFD--ELTELDRVLLRIALANTSRPPL
Mflv_1751|M.gilvum_PYR-GCK DDAEVAGFCGPVFGDLPIPAATAPVE--ELGELDAMLLLIALANSVRPAL
MAB_4761|M.abscessus_ATCC_1997 TG---RDKLDEVFGELPPPSGETFIV--ELSDLDLFLLRITLALLSDRPI
MAV_1612|M.avium_104 SG---PAELTEVFGDMAPPSDNTYVV--ELSDLELFLLRITLALLSNRPI
Mb2419c|M.bovis_AF2122/97 GRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVRPHDIRVGRTPN
Rv2397c|M.tuberculosis_H37Rv GRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVRPHDIRVGRTPN
MMAR_3715|M.marinum_M GRIEQVGSPTEVYDAPANAFVMSFLG--AVSALNGALVRPHDIRVGRTPE
MUL_3658|M.ulcerans_Agy99 GRIEQVGSPTEVYDAPTNAFVMSFLG--AVSALNGALVRPHDIRVGRTPE
MLBr_01892|M.leprae_Br4923 KHLVMFGPR-EVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAAL
* . . : : .
TH_0089|M.thermoresistible__bu LVAGNLDDVAADH-SRDQLVRRLIALGERQTVITATVNE--------VVG
Mvan_4996|M.vanbaalenii_PYR-1 LVVGNLEQVTSDP-ERDLLVSRLVELGREQTVVTAGVNG--------VSD
MSMEG_5645|M.smegmatis_MC2_155 LVVGDFDHVTDDR-NRELLAERLIALGEQQTVVTATVNP--------VSN
Mflv_1751|M.gilvum_PYR-GCK LVVGGIDRVAEDG-SRDLLVQRLAALGDRQTIVTAGANG--------VSG
MAB_4761|M.abscessus_ATCC_1997 LVVGDLEQVRDNA-RRTLAVERLGVIAQNRTVVVGVTNP--------LGT
MAV_1612|M.avium_104 LVVGDLEQVRDNS-RRAIAAERLGAIARQRTVVVGVTNP--------LGA
Mb2419c|M.bovis_AF2122/97 MAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRG
Rv2397c|M.tuberculosis_H37Rv MAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRG
MMAR_3715|M.marinum_M MAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRG
MUL_3658|M.ulcerans_Agy99 MAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRG
MLBr_01892|M.leprae_Br4923 LEAGHYAGGAEEVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGA
: .. . : . : .
TH_0089|M.thermoresistible__bu HDVRARIPVPNTSRAELAHRQKGDQ------------------------
Mvan_4996|M.vanbaalenii_PYR-1 HPV-VQIEVENTTRAELANQQKGGA------------------------
MSMEG_5645|M.smegmatis_MC2_155 PAV-THIAVPNTTPAELASAQKGEK------------------------
Mflv_1751|M.gilvum_PYR-GCK HAV-RQIVVGTITRPEWAGDPGGVA------------------------
MAB_4761|M.abscessus_ATCC_1997 DAPVHDLHDHRILTGRD--------------------------------
MAV_1612|M.avium_104 DAPDHELHDHRIPTGED--------------------------------
Mb2419c|M.bovis_AF2122/97 DAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv DAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M DAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 DAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ
MLBr_01892|M.leprae_Br4923 QAAILDDLEGAHNYQAHEFGD----------------------------