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VSDAPAAELAITARALTLNGPAGPLYGPVDLDVDEGGVTVLVCPPGVGRTALLLTLAGRMRPTSGRLSVL GRTGARSIFGIAAVAAVDGVDDVAQTATVGELVTEKMRWDAPWYRAIRRADDAEVAGFCGPVFGDLPIPA ATAPVEELGELDAMLLLIALANSVRPALLVVGGIDRVAEDGSRDLLVQRLAALGDRQTIVTAGANGVSGH AVRQIVVGTITRPEWAGDPGGVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1751 | - | - | 100% (233) | hypothetical protein Mflv_1751 |
| M. gilvum PYR-GCK | Mflv_2730 | - | 5e-06 | 27.50% (200) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_0193 | - | 7e-06 | 26.09% (207) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3067c | - | 1e-06 | 27.80% (205) | ABC transporter ATP-binding protein |
| M. tuberculosis H37Rv | Rv3041c | - | 1e-06 | 27.80% (205) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01726 | - | 3e-06 | 26.70% (206) | putative ABC transporter protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4761 | - | 5e-27 | 35.18% (199) | hypothetical protein MAB_4761 |
| M. marinum M | MMAR_1660 | - | 8e-06 | 25.85% (205) | ABC transporter ATP-binding protein |
| M. avium 104 | MAV_1612 | - | 7e-32 | 38.12% (202) | hypothetical protein MAV_1612 |
| M. smegmatis MC2 155 | MSMEG_5645 | - | 2e-68 | 58.11% (222) | hypothetical protein MSMEG_5645 |
| M. thermoresistible (build 8) | TH_0089 | - | 4e-71 | 61.26% (222) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1897 | - | 6e-06 | 25.85% (205) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_4996 | - | 4e-76 | 60.94% (233) | hypothetical protein Mvan_4996 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1660|M.marinum_M ----------------------MSEA------------------GPDTAD
MUL_1897|M.ulcerans_Agy99 ----------------------MSEA------------------GPDTAD
Mb3067c|M.bovis_AF2122/97 ---------------MRHDSRVLDNG------------------GPDAAD
Rv3041c|M.tuberculosis_H37Rv ---------------MRHDSRVLDNG------------------GPDAAD
MLBr_01726|M.leprae_Br4923 MATWSRLPGNRRSIAVRHDVRVSQLGPE---------------TGSDAAD
TH_0089|M.thermoresistible__bu ----------------------MP-----DQPEP-------------EQA
Mvan_4996|M.vanbaalenii_PYR-1 ----------------------MP-----DSS-----------------A
MSMEG_5645|M.smegmatis_MC2_155 ----------------------MPQLTAEPDPDA-------------DEQ
Mflv_1751|M.gilvum_PYR-GCK ----------------------MS-----DAP-----------------A
MAB_4761|M.abscessus_ATCC_1997 ----------------------MNAQ---DEPATTPDETDIAISKETNDQ
MAV_1612|M.avium_104 ----------------------MDAN---NEP---------------DDV
MMAR_1660|M.marinum_M PDLLIDFRDVSLRRGGRTLVGPLDWAVELDERWVILGPNGAGKTSLLRMA
MUL_1897|M.ulcerans_Agy99 PDLLIDFRDVSLRRGGRTLVGPLDWAVELDERWVILGPNGAGKTSLLRMA
Mb3067c|M.bovis_AF2122/97 PDLLIDFRNVSLRRNGRTLVGPLDWAVELDERWVIVGPNGAGKTSLLRIA
Rv3041c|M.tuberculosis_H37Rv PDLLIDFRNVSLRRNGRTLVGPLDWAVELDERWVIVGPNGAGKTSLLRIA
MLBr_01726|M.leprae_Br4923 PDLLIDFKDVSLRCEGRVLVGPLDWAVELDERWVIIGPNGAGKTSLLRIA
TH_0089|M.thermoresistible__bu PEPALTARGICMRGPWGPVYGPIDLDIEAGGVTVLHCPPGSGRTALLMTL
Mvan_4996|M.vanbaalenii_PYR-1 PDVAVTARAITMRGPWGPVYGPVDLDIAAGGVTVLVCPPGSGRTALLMTL
MSMEG_5645|M.smegmatis_MC2_155 KPPAITAREITMRGPFGPVYGPVDLDIAEGGVTALVAPSGAGRTALLLTL
Mflv_1751|M.gilvum_PYR-GCK AELAITARALTLNGPAGPLYGPVDLDVDEGGVTVLVCPPGVGRTALLLTL
MAB_4761|M.abscessus_ATCC_1997 APVLITATGLGVDGEHGPLFSGIGLELTSG-FHAIQMPGGPAQHCLLLTL
MAV_1612|M.avium_104 APV-ITAAGLGVDGEHGPLFSGVDLALTPG-FHAIQMPGGPGQTTLLLTL
: : : : . :. : . .: * * .: **
MMAR_1660|M.marinum_M AASEHPSSGVAFVLGERLGRVDVSELRARIGLSSSALAQRIPTDEVVRDL
MUL_1897|M.ulcerans_Agy99 AASEHPSSGVAFVLGERLGRVDVSELRARIGLSSSALAQRIPTDEVVRDL
Mb3067c|M.bovis_AF2122/97 AAAEHPSSGVAFVLGERLGRVDVSELRARVGLSSSALAERVPGDERVRDL
Rv3041c|M.tuberculosis_H37Rv AAAEHPSSGVAFVLGERLGRVDVSELRARVGLSSSALAERVPGDERVRDL
MLBr_01726|M.leprae_Br4923 AAADHPSTGVAYVLGERLGRIDISELRARIGLSSSVLTQRVPSNEVVRDL
TH_0089|M.thermoresistible__bu AGRMRPMSGELTVFGR----TRAPDIFRVAGLAGFDEVDPIPQSVTVRDL
Mvan_4996|M.vanbaalenii_PYR-1 AGRMRPASGSLSVFGR----TRVHDIFAHAALAGIDELDTVAESVTVRDL
MSMEG_5645|M.smegmatis_MC2_155 AGRMKPQSGEVTVLGR----TRAKDIFDISAVAAVEDIDAVPESVTVADV
Mflv_1751|M.gilvum_PYR-GCK AGRMRPTSGRLSVLGR----TGARSIFGIAAVAAVDGVDDVAQTATVGEL
MAB_4761|M.abscessus_ATCC_1997 AGRLKASHGTVNVMGD----TEPRAIRRHCAIAAFADIDELEETVTVQTV
MAV_1612|M.avium_104 AGRFKPSHGTLTVLGE----TTPRAIRRHCSIAAFEGIDDLEDSVTVGTV
*. :. * *:* : .::. : : * :
MMAR_1660|M.marinum_M VVSAGYAVLGRWRERYEDVDYRRAVDMLESLGAEHLADRTYGTLSEGERK
MUL_1897|M.ulcerans_Agy99 VVSAGYAVLGRWRERYEDVDYRRAVDMLESLGAEHLADRTYGTLSEGERK
Mb3067c|M.bovis_AF2122/97 VVSAGYAVLGRWRERYEAVDYHRAIDMLESLGAEHLANRTYGTLSEGERK
Rv3041c|M.tuberculosis_H37Rv VVSAGYAVLGRWRERYEAVDYHRAIDMLESLGAEHLANRTYGTLSEGERK
MLBr_01726|M.leprae_Br4923 VVSAGYAVLGRWRERYEGVDYQRAVDMLESMGAEHLADRTFGTLSEGERK
TH_0089|M.thermoresistible__bu VTEQ-----VRWDA-----PWYRLIPRAGEAELAAVCGPVFGELPL----
Mvan_4996|M.vanbaalenii_PYR-1 ITEQ-----LRWDA-----DWYKLIRRAGEDDVARVCGPVFGDLPL----
MSMEG_5645|M.smegmatis_MC2_155 ITEQ-----RRWDA-----PWYRRVPRAGADDLAALCGPVFGDLPL----
Mflv_1751|M.gilvum_PYR-GCK VTEK-----MRWDA-----PWYRAIRRADDAEVAGFCGPVFGDLPI----
MAB_4761|M.abscessus_ATCC_1997 LAEQ-----RRWLA-----PWFSRVPADTG---RDKLDEVFGELPP----
MAV_1612|M.avium_104 LAEQ-----RRWLA-----PWYSSVPLQSG---PAELTEVFGDMAP----
:.. ** : : .:* :.
MMAR_1660|M.marinum_M RVLIARALMTDPELLLLDEPAAGLDLGGREELVARLADLAADPDAPALVL
MUL_1897|M.ulcerans_Agy99 RVLIARALMTDPELLLLDEPAAGLDLGGREELVARLADLAADPDAPALVL
Mb3067c|M.bovis_AF2122/97 RVLIARALMTDPELLLLDEPAAGLDLGGREELVARLADLAADPDAPALVL
Rv3041c|M.tuberculosis_H37Rv RVLIARALMTDPELLLLDEPAAGLDLGGREELVARLADLAADPDAPALVL
MLBr_01726|M.leprae_Br4923 RVLIARALMTDPELLLLDEPAASLDLGAREELVSRLADLAADAYAPALVL
TH_0089|M.thermoresistible__bu -------------------PPLGEYVGELSELDRMLLRIALANTRRPALL
Mvan_4996|M.vanbaalenii_PYR-1 -------------------PPLSEYVEELTELDGLLLRIALANTGRPPLL
MSMEG_5645|M.smegmatis_MC2_155 -------------------PPLGEYFDELTELDRVLLRIALANTSRPPLL
Mflv_1751|M.gilvum_PYR-GCK -------------------PAATAPVEELGELDAMLLLIALANSVRPALL
MAB_4761|M.abscessus_ATCC_1997 -------------------PSGETFIVELSDLDLFLLRITLALLSDRPIL
MAV_1612|M.avium_104 -------------------PSDNTYVVELSDLELFLLRITLALLSNRPIL
*. . :* * :: :*
MMAR_1660|M.marinum_M VTHHVEEVPPGFSHCLLLAEGHVVASGLLSDVLTAENLSAAFGQQIAVDF
MUL_1897|M.ulcerans_Agy99 VTHHVEEVPPGFSHCLLLAEGHVVASGLLSDVLTAENLWAAFGQQIAVDF
Mb3067c|M.bovis_AF2122/97 VTHHVEEIPPGFSHCLLLSEARVVAAGLLPDALTAENLSTAFGQEITLEV
Rv3041c|M.tuberculosis_H37Rv VTHHVEEIPPGFSHCLLLSEARVVAAGLLPDALTAENLSTAFGQEITLEV
MLBr_01726|M.leprae_Br4923 VTHHVEEVPPGFSHCLLLSEAKVVAAGLLSDVLTAENLSTAFGQSIALDV
TH_0089|M.thermoresistible__bu VAGNLDDVAADHSRDQLVRRLIALGE---RQTVITATVNEVVGHDVRARI
Mvan_4996|M.vanbaalenii_PYR-1 VVGNLEQVTSDPERDLLVSRLVELGR---EQTVVTAGVNGVSDHPV-VQI
MSMEG_5645|M.smegmatis_MC2_155 VVGDFDHVTDDRNRELLAERLIALGE---QQTVVTATVNPVSNPAV-THI
Mflv_1751|M.gilvum_PYR-GCK VVGGIDRVAEDGSRDLLVQRLAALGD---RQTIVTAGANGVSGHAV-RQI
MAB_4761|M.abscessus_ATCC_1997 VVGDLEQVRDNARRTLAVERLGVIAQ---NRTVVVGVTNPLGTDAPVHDL
MAV_1612|M.avium_104 VVGDLEQVRDNSRRAIAAERLGAIAR---QRTVVVGVTNPLGADAPDHEL
*. .: : . : . :. .: . .
MMAR_1660|M.marinum_M VDGRYFARRIRARAAHRRQQ
MUL_1897|M.ulcerans_Agy99 VDGRYFARRIRARAAHRRQQ
Mb3067c|M.bovis_AF2122/97 ADGRYFARRRRSRAAHRRQS
Rv3041c|M.tuberculosis_H37Rv ADGRYFARRRRSRAAHRRQS
MLBr_01726|M.leprae_Br4923 IDGRYFARRVRARAAHRRQL
TH_0089|M.thermoresistible__bu PVPNTSRAELAHRQKGDQ--
Mvan_4996|M.vanbaalenii_PYR-1 EVENTTRAELANQQKGGA--
MSMEG_5645|M.smegmatis_MC2_155 AVPNTTPAELASAQKGEK--
Mflv_1751|M.gilvum_PYR-GCK VVGTITRPEWAGDPGGVA--
MAB_4761|M.abscessus_ATCC_1997 HDHRILTGRD----------
MAV_1612|M.avium_104 HDHRIPTGED----------
.