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MDANNEPDDVAPVITAAGLGVDGEHGPLFSGVDLALTPGFHAIQMPGGPGQTTLLLTLAGRFKPSHGTLT VLGETTPRAIRRHCSIAAFEGIDDLEDSVTVGTVLAEQRRWLAPWYSSVPLQSGPAELTEVFGDMAPPSD NTYVVELSDLELFLLRITLALLSNRPILVVGDLEQVRDNSRRAIAAERLGAIARQRTVVVGVTNPLGADA PDHELHDHRIPTGED
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1612 | - | - | 100% (225) | hypothetical protein MAV_1612 |
| M. avium 104 | MAV_1567 | - | 7e-07 | 27.27% (187) | ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1384 | - | 1e-08 | 30.14% (209) | drugs-transport transmembrane ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_1751 | - | 7e-32 | 38.12% (202) | hypothetical protein Mflv_1751 |
| M. tuberculosis H37Rv | Rv1349 | - | 1e-08 | 30.14% (209) | drugs-transport transmembrane ATP-binding protein ABC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4761 | - | 2e-92 | 73.99% (223) | hypothetical protein MAB_4761 |
| M. marinum M | MMAR_4036 | - | 3e-06 | 27.23% (191) | transmembrane ATP-binding protein ABC transporter |
| M. smegmatis MC2 155 | MSMEG_5645 | - | 2e-40 | 44.95% (218) | hypothetical protein MSMEG_5645 |
| M. thermoresistible (build 8) | TH_0089 | - | 3e-32 | 39.02% (205) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3901 | - | 2e-06 | 27.23% (191) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_4996 | - | 2e-32 | 38.54% (205) | hypothetical protein Mvan_4996 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1612|M.avium_104 --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
Mb1384|M.bovis_AF2122/97 MIRTWIALVPNDHRARLIGFALLAFCSVVARAVGTVLLVPLMAALFGEAP
Rv1349|M.tuberculosis_H37Rv MIRTWIALVPNDHRARLIGFALLAFCSVVARAVGTVLLVPLMAALFGEAP
MMAR_4036|M.marinum_M MIRTWIGLVPADRRGKLILCAAVGVLSVVVRAIGTVLLVPLIGALFSSTP
MUL_3901|M.ulcerans_Agy99 MIRTWIGLVPADRRGKLILCAAVGVLSVVVRAIGTVLLVPLIGALFSSTP
MAV_1612|M.avium_104 --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
Mb1384|M.bovis_AF2122/97 QRAWLWLGWLSAATVAGWVLDAVTARIGIELGFAVLNHTQHDVADRLPVV
Rv1349|M.tuberculosis_H37Rv QRAWLWLGWLSAATVAGWVLDAVTARIGIELGFAVLNHTQHDVADRLPVV
MMAR_4036|M.marinum_M QQALVWLGWLTAATVSGWVIDAIGARVGFELGFAVLDHSQHGVADRLPGV
MUL_3901|M.ulcerans_Agy99 QQALVWLGWLTAATVSGWVIDAIGARVGFELGFAVLDHSQHGVADRLPGV
MAV_1612|M.avium_104 --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
Mb1384|M.bovis_AF2122/97 RLDWFTAENTATARQAIAATGPELVGLVVNLVTPLTSAILLPAVIALALL
Rv1349|M.tuberculosis_H37Rv RLDWFTAENTATARQAIAATGPELVGLVVNLVTPLTSAILLPAVIALALL
MMAR_4036|M.marinum_M RLDWFTADNTATARQAIAASGPELVGLVVYLLTPLVSAVLLPLAIGLALL
MUL_3901|M.ulcerans_Agy99 RLDWFTADNTATARQAIAASGPELVGLVVYLLTPLVSAVLLPLAIGLALL
MAV_1612|M.avium_104 --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
Mb1384|M.bovis_AF2122/97 PISWQLGVAALAGVPLLLGALWASAAFARRADTAADKANTALTERIIEFA
Rv1349|M.tuberculosis_H37Rv PISWQLGVAALAGVPLLLGALWASAAFARRADTAADKANTALTERIIEFA
MMAR_4036|M.marinum_M PISWQLGLAALAGVPLLLGALWASGRFARRADKVADEANIALTERIIEFA
MUL_3901|M.ulcerans_Agy99 PISWQLGLAALAGVPLLLGALWASGRFARRADKVADEANIALTERIIEFA
MAV_1612|M.avium_104 --------------------------------------------------
MAB_4761|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0089|M.thermoresistible__bu --------------------------------------------------
Mvan_4996|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5645|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1751|M.gilvum_PYR-GCK --------------------------------------------------
Mb1384|M.bovis_AF2122/97 RTQQALRAARRVEPARSLVGNALASQHTATMRLLGMQIPGQLLFSIASQL
Rv1349|M.tuberculosis_H37Rv RTQQALRAARRVEPARSLVGNALASQHTATMRLLGMQIPGQLLFSIASQL
MMAR_4036|M.marinum_M RTQQALRAARRVEPARSLVGSALARQHGSLMRLFAMQVPGQLLFSIASQL
MUL_3901|M.ulcerans_Agy99 RTQQALRAARRVEPARSLVGSALARQHGSLMRLFAMQVPGQLLFSSASQL
MAV_1612|M.avium_104 ---------------------------------MDAN---NEP-------
MAB_4761|M.abscessus_ATCC_1997 ---------------------------------MNAQ---DEPATTPDET
TH_0089|M.thermoresistible__bu ---------------------------------MP-----DQPEP-----
Mvan_4996|M.vanbaalenii_PYR-1 ---------------------------------MP-----DSS-------
MSMEG_5645|M.smegmatis_MC2_155 ---------------------------------MPQLTAEPDPDA-----
Mflv_1751|M.gilvum_PYR-GCK ---------------------------------MS-----DAP-------
Mb1384|M.bovis_AF2122/97 ALIVLAGTTAALTITGTLTVPEAIALIVVMVRYLEPFTAVSELAPALEST
Rv1349|M.tuberculosis_H37Rv ALIVLAGTTAALTITGTLTVPEAIALIVVMVRYLEPFTAVSELAPALEST
MMAR_4036|M.marinum_M ALIVLAGATAALTVGGTLTVPEAIALIVVIARYLEPFTAVSELAPALQSV
MUL_3901|M.ulcerans_Agy99 ALIVLAGATAALTVGGTLTVPEAIALIVVIARYLEPFTAVSELAPALQSV
:
MAV_1612|M.avium_104 --------------------------DDVAPV-ITAAGLGVDGEHGPLFS
MAB_4761|M.abscessus_ATCC_1997 DIAISKE------------------TNDQAPVLITATGLGVDGEHGPLFS
TH_0089|M.thermoresistible__bu --------------------------EQAPEPALTARGICMRGPWGPVYG
Mvan_4996|M.vanbaalenii_PYR-1 ----------------------------APDVAVTARAITMRGPWGPVYG
MSMEG_5645|M.smegmatis_MC2_155 --------------------------DEQKPPAITAREITMRGPFGPVYG
Mflv_1751|M.gilvum_PYR-GCK ----------------------------AAELAITARALTLNGPAGPLYG
Mb1384|M.bovis_AF2122/97 RATLGRIGSVLTAPVMVAGSGTWRDGAVVPRIEFDDVAFGYDGGSGPVLD
Rv1349|M.tuberculosis_H37Rv RATLGRIGSVLTAPVMVAGSGTWRDGAVVPRIEFDDVAFGYDGGSGPVLD
MMAR_4036|M.marinum_M RAMLDRIRSVLTAPAVAAGTATLDDGPAAARIEFDHVAFSYDGATEPVLD
MUL_3901|M.ulcerans_Agy99 RAMLDRIRSVLTAPAVAAGTATLDDGPAAARIEFDHVAFSYDGATEPVLD
. : * *: .
MAV_1612|M.avium_104 GVDLALTPG-FHAIQMPGGPGQTTLLLTLAGRFKPSHG-------TLTVL
MAB_4761|M.abscessus_ATCC_1997 GIGLELTSG-FHAIQMPGGPAQHCLLLTLAGRLKASHG-------TVNVM
TH_0089|M.thermoresistible__bu PIDLDIEAGGVTVLHCPPGSGRTALLMTLAGRMRPMSG-------ELTVF
Mvan_4996|M.vanbaalenii_PYR-1 PVDLDIAAGGVTVLVCPPGSGRTALLMTLAGRMRPASG-------SLSVF
MSMEG_5645|M.smegmatis_MC2_155 PVDLDIAEGGVTALVAPSGAGRTALLLTLAGRMKPQSG-------EVTVL
Mflv_1751|M.gilvum_PYR-GCK PVDLDVDEGGVTVLVCPPGVGRTALLLTLAGRMRPTSG-------RLSVL
Mb1384|M.bovis_AF2122/97 GVSFCLQPGTTTAIVGPSGCGKSTILALIAGLHQPTRGRVLIDGTDVATL
Rv1349|M.tuberculosis_H37Rv GVSFCLQPGTTTAIVGPSGCGKSTILALIAGLHQPTRGRVLIDGTDVATL
MMAR_4036|M.marinum_M GVSFCLQPGTTTAIVGPSGSGKSTILALIAGLHQPTGGRILIDGADAATL
MUL_3901|M.ulcerans_Agy99 GVSFCLQPGTTTAIVGPSGSGKSTILALIAGLHQPTGGRILIDGADAATL
:.: : * .: * * .: :* :** :. * .:
MAV_1612|M.avium_104 GETTPRAIRRHCSIAAFEGIDDLEDSVTVGTVLAEQRRWLAPWYSSVPLQ
MAB_4761|M.abscessus_ATCC_1997 GDTEPRAIRRHCAIAAFADIDELEETVTVQTVLAEQRRWLAPWFSRVPAD
TH_0089|M.thermoresistible__bu GRTRAPDIFRVAGLAGFDEVDPIPQSVTVRDLVTEQVRWDAPWYRLIPRA
Mvan_4996|M.vanbaalenii_PYR-1 GRTRVHDIFAHAALAGIDELDTVAESVTVRDLITEQLRWDADWYKLIRRA
MSMEG_5645|M.smegmatis_MC2_155 GRTRAKDIFDISAVAAVEDIDAVPESVTVADVITEQRRWDAPWYRRVPRA
Mflv_1751|M.gilvum_PYR-GCK GRTGARSIFGIAAVAAVDGVDDVAQTATVGELVTEKMRWDAPWYRAIRRA
Mb1384|M.bovis_AF2122/97 DARAQQAVCSVVFQHPYLFHGTIRDNVFAADPGASDDQFAQAVRLARVDE
Rv1349|M.tuberculosis_H37Rv DARAQQAVCSVVFQHPYLFHGTIRDNVFAADPGASDDQFAQAVRLARVDE
MMAR_4036|M.marinum_M DAHTRRTLSSVVFQHPYLFHGSIRENVLAGNPGADQDQLGRAIRLARVDE
MUL_3901|M.ulcerans_Agy99 DAHTRRTLSSVVFQHPYLFHGSIRENVLAGNPGADQDQLGRAIRLARVDE
. : . : :.. . :.. :
MAV_1612|M.avium_104 SG---PAELTEVFGDMAPPSDNTYVVELSDLELFLLRITLALLSNRP---
MAB_4761|M.abscessus_ATCC_1997 TG---RDKLDEVFGELPPPSGETFIVELSDLDLFLLRITLALLSDRP---
TH_0089|M.thermoresistible__bu GEAELAAVCGPVFGELPLPPLGEYVGELSELDRMLLRIALANTRRPA---
Mvan_4996|M.vanbaalenii_PYR-1 GEDDVARVCGPVFGDLPLPPLSEYVEELTELDGLLLRIALANTGRPP---
MSMEG_5645|M.smegmatis_MC2_155 GADDLAALCGPVFGDLPLPPLGEYFDELTELDRVLLRIALANTSRPP---
Mflv_1751|M.gilvum_PYR-GCK DDAEVAGFCGPVFGDLPIPAATAPVEELGELDAMLLLIALANSVRPA---
Mb1384|M.bovis_AF2122/97 LIARLPDGANTIVGEAGSALSGGERQRVSIARALLKAAPVLLVDEATSAL
Rv1349|M.tuberculosis_H37Rv LIARLPDGANTIVGEAGSALSGGERQRVSIARALLKAAPVLLVDEATSAL
MMAR_4036|M.marinum_M LIDRLPDGADTVVGEAGSALSGGERQRVSIARALLKDAPMLLVDEATSAL
MUL_3901|M.ulcerans_Agy99 LIDRLPDGADTVVGEAGSALSGGERQRVSIARALLKDAPMLLVDEATSAL
:.*: . .: .* .: .
MAV_1612|M.avium_104 -----ILVVGDLEQVRDNSRRAIAAERLGAIARQRTVVVGVTNPLGADAP
MAB_4761|M.abscessus_ATCC_1997 -----ILVVGDLEQVRDNARRTLAVERLGVIAQNRTVVVGVTNPLGTDAP
TH_0089|M.thermoresistible__bu -----LLVAGNLDDVAADHSRDQLVRRLIALGERQTVITATVNEVVGHDV
Mvan_4996|M.vanbaalenii_PYR-1 -----LLVVGNLEQVTSDPERDLLVSRLVELGREQTVVTAGVNGVSDHPV
MSMEG_5645|M.smegmatis_MC2_155 -----LLVVGDFDHVTDDRNRELLAERLIALGEQQTVVTATVNPVSNPAV
Mflv_1751|M.gilvum_PYR-GCK -----LLVVGGIDRVAEDGSRDLLVQRLAALGDRQTIVTAGANGVSGHAV
Mb1384|M.bovis_AF2122/97 DAENEAAVVDALAADPRSRTRVIVAHRLASIRHADRVLFVDDGRVVEDGS
Rv1349|M.tuberculosis_H37Rv DAENEAAVVDALAADPRSRTRVIVAHRLASIRHADRVLFVDDGRVVEDGS
MMAR_4036|M.marinum_M DTENEVAVVDALTADPQSRTRVIVAHRLASIRHADRVLFVEDGRVVEDGS
MUL_3901|M.ulcerans_Agy99 DTENEVAVVDALTADPQSRTRVIVAHRLASIRHADRVLFVEDGRVVEDGS
*.. : . * . ** : :: . :
MAV_1612|M.avium_104 DHELHDHRIPTGED---------------
MAB_4761|M.abscessus_ATCC_1997 VHDLHDHRILTGRD---------------
TH_0089|M.thermoresistible__bu RARIPVPNTSRAELAHRQKGDQ-------
Mvan_4996|M.vanbaalenii_PYR-1 -VQIEVENTTRAELANQQKGGA-------
MSMEG_5645|M.smegmatis_MC2_155 -THIAVPNTTPAELASAQKGEK-------
Mflv_1751|M.gilvum_PYR-GCK -RQIVVGTITRPEWAGDPGGVA-------
Mb1384|M.bovis_AF2122/97 ISELLTAGGRFSQFWRQQHEAAEWQILAE
Rv1349|M.tuberculosis_H37Rv ISELLTAGGRFSQFWRQQHEAAEWQILAE
MMAR_4036|M.marinum_M IDELLAAQGRFHEFWRQQHDAAEWRIRTG
MUL_3901|M.ulcerans_Agy99 IDELLAAQGRFHEFWRQQHDAAEWRIRTG
: .