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MIETHGLTKSFGPRRALDDVTVTFPAGAVTALLGLNGAGKTTLLRLIAGLDRPDGGTVTVSGRTPFGDPH LVGAHLGPDALDPRHTVARHLRWLAALAGVDDGRVAQVLEETGLSAQRCNRIGGLSLGARQRLAIAGALL CRPQALLFDEPLNGLDVPGIVWFRGLLRQLADTGCVVVVATHLLAEVVLSADRVILLEAGQPRLDGALAD VIPAGADPRDWLESRLLDCVACA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2047 | - | - | 100% (233) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_0712 | - | 2e-45 | 48.53% (204) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4499 | - | 1e-28 | 38.25% (217) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 4e-26 | 38.53% (218) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_4301 | - | 1e-102 | 78.11% (233) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 4e-26 | 38.53% (218) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00590 | - | 1e-21 | 31.82% (220) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4215c | - | 2e-43 | 45.74% (223) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_4220 | - | 9e-26 | 34.88% (215) | antibiotic ABC transporter ATP-binding protein |
| M. avium 104 | MAV_1362 | - | 1e-25 | 35.62% (219) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5312 | - | 2e-79 | 66.09% (233) | ABC-type multidrug transport system ATPase component |
| M. thermoresistible (build 8) | TH_2788 | - | 1e-48 | 48.05% (231) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_1424 | - | 5e-25 | 37.14% (210) | transmembrane ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 MMTRAQQPVLTVRSGPSQRSFAAGPDVIVGSDLHADLRVAHPLIDRAHLL
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 LRFEQGSWVPIDNNSQSRIYVDARRVPLIDIRDGLAMNLGRADGPRITFE
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK -----------------------------MRHGPTTSHDIGSRDGLGRRD
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 VGHHQGVIGLLPPPETMPGVAPADRPPSGGPSPSGPGYRPGPPSYPSRPS
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK VVDGDRAGGNRRSRGSRRPRYRRRVRDHLRGADAGRTRRPDPASGRLARP
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 WPSPPPDRPPDPVASAQLTSAIPLLPPPARPGAHTTASHYPDRTVDVLGA
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK GRRQGRATRRRCARRRGAEDDLPRRLLPAAQRGERGHRPRDPRARPAHRG
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 DSGLAPALADTISIGRAASNDIVVSDVLTSRHHAFLTPTRIGTEIRDAHS
Mvan_2047|M.vanbaalenii_PYR-1 -----------------------------------------------MIE
Mflv_4301|M.gilvum_PYR-GCK DQRESARGSDGAGRRRVAAYRRPVEAGEQVIVQRHQDDRPADPVQLRMIE
MSMEG_5312|M.smegmatis_MC2_155 -----------------------------------------------MIE
MAB_4215c|M.abscessus_ATCC_199 -----------------------------------------------MIE
TH_2788|M.thermoresistible__bu -------------------------------------------MMAAMIE
Mb2419c|M.bovis_AF2122/97 --------------------------------------------MTYAIV
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------MTYAIV
MMAR_4220|M.marinum_M ---------------------------------------MATDIGSTPIE
MAV_1362|M.avium_104 ---------------------------------------MATD-GFAPIE
MLBr_00590|M.leprae_Br4923 ----------------------------------MSSACTVPETPEVVIR
MUL_1424|M.ulcerans_Agy99 INGTFVNGIRVGSAILSDGDIVTIGNVDLAFTGGTLARHTQVATRAGRLE
:
Mvan_2047|M.vanbaalenii_PYR-1 THGLTKSFGPRRALDDVTVTFPAGAVTALLGLNGAGKTTLLRLIAGLDRP
Mflv_4301|M.gilvum_PYR-GCK TSGLTKSFGPKKVLDDVSVCFPGGTVTALLGLNGAGKTTLLRLIAGLDRP
MSMEG_5312|M.smegmatis_MC2_155 ITRLVKRFGATVAVDDVTVSFPAGTVTGLLGLNGAGKTTLLRLIAGLDHP
MAB_4215c|M.abscessus_ATCC_199 LRSLTKVYGQTPAVDDLSVTIESGVVTGFLGPNGAGKSTTLRMIVGLARP
TH_2788|M.thermoresistible__bu LTALTKVFGRTRAVDDLTCTVEPGVVTGFLGPNGAGKTTTMRLILGLDRP
Mb2419c|M.bovis_AF2122/97 VADATKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQP
Rv2397c|M.tuberculosis_H37Rv VADATKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQP
MMAR_4220|M.marinum_M IRGLTKNFGSVRALDELDLTVREGEVHGFLGPNGAGKSTTIRILLGLVKA
MAV_1362|M.avium_104 IRGLTKNFGAVRALDGLDLTVREGEVHGFLGPNGAGKSTTIRILLGLVKA
MLBr_00590|M.leprae_Br4923 LRGVCKHYGSILAVSNLDLDIHSAEVLALLGPNGAGKTTTVEMCEGFVRP
MUL_1424|M.ulcerans_Agy99 VNAVNFSINGNGLLENISLTARPGTLTAVIGGSGAGKTTLSRLIAGYTSP
. :. : . : ..:* .*:**:* . * .
Mvan_2047|M.vanbaalenii_PYR-1 DGGTVTVSGR---TPFGDPH-LVGAHLGPDALDPRHTVARHLRWLAALAG
Mflv_4301|M.gilvum_PYR-GCK DGGTVTVDGR---APGGDPN-QVGVHLGPGALDPRHTVGRHLKWLAALAG
MSMEG_5312|M.smegmatis_MC2_155 DSGDVTLCGRP-IRDHADPMRTLGVHFDPDAMDPRHTAERHLRWLAALGG
MAB_4215c|M.abscessus_ATCC_199 TSGTATIGGKQ-YHEIDHPLREVGALLDPKQFHPNRSARNHLRWIAAAND
TH_2788|M.thermoresistible__bu TSGTATIDGRR-YRDLRDPLRTVGALLDARAVHPARSARNHLRWLAAANR
Mb2419c|M.bovis_AF2122/97 DTGTITINGRD-VTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK
Rv2397c|M.tuberculosis_H37Rv DTGTITINGRD-VTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK
MMAR_4220|M.marinum_M DSGSVRLLGGNPWTDAVELHRQIAYVPGDVTLWPSLTGGEIIDLLARMRG
MAV_1362|M.avium_104 DGGTVRLLGGDPWTQAVELHRQIAYVPGDVTLWPSLTGGEIIDLLARMRG
MLBr_00590|M.leprae_Br4923 DAGTIEVLGLDPITDNARLRARIGVMLQGGGGYPAARAGEMLNLVASYAA
MUL_1424|M.ulcerans_Agy99 SSGTVTFEGHNIHADYASLRSRIGMVPQDDVVHRKLTVNQALGYAAELRL
* . * :. :
Mvan_2047|M.vanbaalenii_PYR-1 VD-------DGRVAQVLEETGLSAQRCNRIGGLSLGARQRLAIAGALLCR
Mflv_4301|M.gilvum_PYR-GCK TE-------VRRIDDVLDETGLHAQRRERIGALSLGARQRLSIAGALLCS
MSMEG_5312|M.smegmatis_MC2_155 ID-------GGRVDAVLAEVGLDELRHRRIANLSMGARQRLAIASALLGD
MAB_4215c|M.abscessus_ATCC_199 IS-------AQRVDEVLEMVGLTEVANRHAGTFSLGMSQRLGIAVALLGD
TH_2788|M.thermoresistible__bu IP-------QRRVDEVLELVGLTAVAARPAGTLSLGMSQRLGIAGALLGD
Mb2419c|M.bovis_AF2122/97 RPKAEI---KAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVD
Rv2397c|M.tuberculosis_H37Rv RPKAEI---KAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVD
MMAR_4220|M.marinum_M GID------QDRRAELIERFGLDP--HKKSRTYSKGNRQKVSLISAFSSR
MAV_1362|M.avium_104 GID------KRRRAELIERFDLDP--HKKARTYSKGNRQKVSLISAFSSR
MLBr_00590|M.leprae_Br4923 DP--------LDPEWLLETLGLTDVARTTYRRLSGGQQQRLALACTLVGR
MUL_1424|M.ulcerans_Agy99 PPDTSKEGRAQVVAGVLDELGLTQHADTRVDKLSGGQRKRASVALELLTG
:: .* * * :: .: :
Mvan_2047|M.vanbaalenii_PYR-1 PQALLFDEPLNGLDVPGIVWFRGLLRQLADTG-CVVVVATHLLAEVVLSA
Mflv_4301|M.gilvum_PYR-GCK PRALLFDEPLNGLDVPGIVWFRGLLRKLADDG-CAVVVATHLLAEVVLSA
MSMEG_5312|M.smegmatis_MC2_155 PQVLVFDEPVNGLDVPGIVWLRELLHRLAGRG-CTVVVASHLLGEVVLTA
MAB_4215c|M.abscessus_ATCC_199 PKVLLFDEPVNGLDPEGIHWIRTLMQSLAAQG-RTVLVSSHLLSEMANTA
TH_2788|M.thermoresistible__bu PPVLLFDEPVNGLDPEGIRWVRTLMRTMAAEG-RTVLVSSHLLAEMANTA
Mb2419c|M.bovis_AF2122/97 PEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVA
Rv2397c|M.tuberculosis_H37Rv PEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVA
MMAR_4220|M.marinum_M ARLLLLDEPSSGLDPLMENVFQQCVDEARGRG-VTVLLSSHILAETEALC
MAV_1362|M.avium_104 ARLLLLDEPSSGLDPLMENVFQQCVAQARDRG-TTVLLSSHILAETEALC
MLBr_00590|M.leprae_Br4923 PELVFLDEPTAGMDTHARLLVWELIDTLRRDG-VTVVLTTHQLKEAEELA
MUL_1424|M.ulcerans_Agy99 PSLLILDEPTSGLDPALDLQVMMMLRQLADAG-RVVLVVTHSLTYLDICD
. :.:*** .:* . : ..:: :*
Mvan_2047|M.vanbaalenii_PYR-1 DRVILLEAG-----------------------------------------
Mflv_4301|M.gilvum_PYR-GCK DRVLMLDCG-----------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 DRLLVLQRG-----------------------------------------
MAB_4215c|M.abscessus_ATCC_199 DQLVVIGRGRLIAA------------------------------------
TH_2788|M.thermoresistible__bu DRLLVIGRGRLIAS------------------------------------
Mb2419c|M.bovis_AF2122/97 DRIAVLHKGRIEQVGSPTDV-----------------------------Y
Rv2397c|M.tuberculosis_H37Rv DRIAVLHKGRIEQVGSPTDV-----------------------------Y
MMAR_4220|M.marinum_M ERITIIRAGRTVES------------------------------------
MAV_1362|M.avium_104 ERVTIIRAGKTIES------------------------------------
MLBr_00590|M.leprae_Br4923 DRLVIIDHGRMIAAG-----------------------------------
MUL_1424|M.ulcerans_Agy99 QVLLMAPGGKTAFLGPPDQIGPAMGTTNWAHIFAKVGTDPDEANRRFLAQ
: : : *
Mvan_2047|M.vanbaalenii_PYR-1 -----------------------QPR------------------------
Mflv_4301|M.gilvum_PYR-GCK -----------------------RPR------------------------
MSMEG_5312|M.smegmatis_MC2_155 -----------------------KVK------------------------
MAB_4215c|M.abscessus_ATCC_199 --------TSMHEFVSRAGADVVRVRSPQIDILRSAAEESGFSVVGGERT
TH_2788|M.thermoresistible__bu --------TSVAEFVGSTAAERVRVRSPEMDTLRGLLADAGVEVR-LEPD
Mb2419c|M.bovis_AF2122/97 DAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGV
Rv2397c|M.tuberculosis_H37Rv DAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGV
MMAR_4220|M.marinum_M ---------GSLASMRHLSRTSIKAEMIGDPGDLTRIQGVEDVTVDGNTL
MAV_1362|M.avium_104 ---------GSLSSMRHLSRTSIKAEMTGDPGDLRRIKGVEDISIEGNTL
MLBr_00590|M.leprae_Br4923 -------TPTELMHTGAKDQLRFSAPPRLDLSLLAFALPEDYKTTELTPG
MUL_1424|M.ulcerans_Agy99 HRAAAPAQPQTPTDLGAPAHTSVRRQFSTITRRQVRLVIADRAYFAFLAI
Mvan_2047|M.vanbaalenii_PYR-1 -------LDGALADVIPAGAD-----------PRDWLESRLLDCVACA--
Mflv_4301|M.gilvum_PYR-GCK -------VHGPLDNVIPAGDQ-----------PRDWLESALLDGARCA--
MSMEG_5312|M.smegmatis_MC2_155 -------VAGALADVTPAGAD-----------PRDHLESLLLETVDA---
MAB_4215c|M.abscessus_ATCC_199 GEPGVLEISGALIEQVGELAARRGVTLYELSPQRVSLEDAYLSLTDDAVQ
TH_2788|M.thermoresistible__bu G--AALTVRGAAPEVVGELAARNGITLHELSVQRASLEDAYLELTDAAVE
Mb2419c|M.bovis_AF2122/97 LRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYV
Rv2397c|M.tuberculosis_H37Rv LRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYV
MMAR_4220|M.marinum_M HVQVDSESLGELVRVLGEAGVR------SLVSQPPTLEELFLRHYS-VGP
MAV_1362|M.avium_104 RAQVDSESLGELIRVLGDAGVR------SLVSQPPTLEELFLRHYDTSGT
MLBr_00590|M.leprae_Br4923 EYLVAGPIDPQVLATVTAWCAQINVLTTNMRVEQHSLEDVFLDLTGRKLR
MUL_1424|M.ulcerans_Agy99 LPFILGTLSLTVPGDTGFGIADATSQTPDEAAQILNLLSIAAVFMGTALT
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 YRSQVNDPLAARATGAVADAEGTH--------------------------
TH_2788|M.thermoresistible__bu YR-------------AVPR-------------------------------
Mb2419c|M.bovis_AF2122/97 RATRVPPIAGGVSGVDDAGVERVKVTST----------------------
Rv2397c|M.tuberculosis_H37Rv RATRVPPIAGGVSGVDDAGVERVKVTST----------------------
MMAR_4220|M.marinum_M DGE-AQHRSGTGVAAR----------------------------------
MAV_1362|M.avium_104 DGERGAHEAEVSLS------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 IRDLIGERAIFRREQAVGLSAWAYLSAKVSVFCAFAVAQAAIATGIVLLG
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 KGAPTQPAVLLGNPSFELFTAVAATCMASAILGLLLSPIARSNEQIMPLL
Mvan_2047|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2788|M.thermoresistible__bu --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4220|M.marinum_M --------------------------------------------------
MAV_1362|M.avium_104 --------------------------------------------------
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
MUL_1424|M.ulcerans_Agy99 VVSLMLQLVLAGGVVPVTDRIFLDQLSWLTPARWGYAASAATVNLRELVP
Mvan_2047|M.vanbaalenii_PYR-1 -------------------------------------------
Mflv_4301|M.gilvum_PYR-GCK -------------------------------------------
MSMEG_5312|M.smegmatis_MC2_155 -------------------------------------------
MAB_4215c|M.abscessus_ATCC_199 -------------------------------------------
TH_2788|M.thermoresistible__bu -------------------------------------------
Mb2419c|M.bovis_AF2122/97 -------------------------------------------
Rv2397c|M.tuberculosis_H37Rv -------------------------------------------
MMAR_4220|M.marinum_M -------------------------------------------
MAV_1362|M.avium_104 -------------------------------------------
MLBr_00590|M.leprae_Br4923 -------------------------------------------
MUL_1424|M.ulcerans_Agy99 GSMSPEDSHWTHSTTAWLFDMAMLAALSVVYSAVVWWRIRLKR