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KLHRLALTNYRGITHRDIEFPDRGVVVVSGPNEAGKSSMLEALDLLLESKDRSSKKEVKQVKPTHADVGA EVTAEISAGPYRFVYRKRFHKRPETELTVLTPRREQLTGDEAHERVRAILAESVDLDLWQAQRVLQSAPT SAADLSGCNALSRALDVVAGEVDDVSATGAGNVESLLVDRVEEEYRRYFTSTGRATGEWAAATARLRAAD EEVARCAAAMAEVDEAVRRHAALTTDMAQLAVETASAAERLQSARNAAAAVAVLQGELDQATARAEAARS VHAASKAALAQRRRARADLDERSATVTSLQTESDTAADELDTANEMQVAAEEAAGKARSALAACQERVDA ARVAVQRLADREEADRLTGRIATIERHGRELEAVQRDLTAITLTDALLADIETAAAAVERATAAVEQTSA HIEVTAAADVEVRIGDADMTLRAGDTWAAAVGTATGIDLPGVLSVQVIPGASAAATAAALDTAAARLADA LRAAGVDDVEAARALDRRRHELSAAGRQIRAILEALAADDSVDQLRARLADLQARTPAEEGLFDTDTRGS LDPAAQRLELVEATAAHQQAIRDCETHRKVAEEAAKLSAKRGLHAARLLEKLQAAQAELAAAGARLAEQR AATSDDELAVKAEADAEAAAAAEAAVARVGAELAGHEPEAVAAALVDAERAAAEVGARHHEVGEALREIA AQLKVYGTEGRKGGLDAAETERGRAEAEFVRVQRRARAAELLRSVMGRHRDAMRQRYVDPFRGEVERLGR IVFGDSFEVDVDSSLCIGNRTLSGRTVPYESLSGGAKEQLGIVARLAGAALVAKEDSVPVVIDDALGFTD TERLTKMAEVFDAVAGDGQVIILTCSPQRYAGVRTAQHIELIAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4435 | - | - | 100% (885) | hypothetical protein Mvan_4435 |
| M. vanbaalenii PYR-1 | Mvan_2175 | - | 1e-16 | 27.14% (667) | chromosome segregation protein SMC |
| M. vanbaalenii PYR-1 | Mvan_1098 | - | 3e-15 | 23.37% (933) | SMC domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1309 | - | 0.0 | 55.66% (884) | hypothetical protein Mb1309 |
| M. gilvum PYR-GCK | Mflv_2256 | - | 0.0 | 74.46% (885) | hypothetical protein Mflv_2256 |
| M. tuberculosis H37Rv | Rv1278 | - | 0.0 | 55.66% (884) | hypothetical protein Rv1278 |
| M. leprae Br4923 | MLBr_01120 | - | 0.0 | 51.93% (882) | hypothetical protein MLBr_01120 |
| M. abscessus ATCC 19977 | MAB_1421 | - | 0.0 | 48.53% (884) | hypothetical protein MAB_1421 |
| M. marinum M | MMAR_4142 | - | 0.0 | 53.45% (883) | hydrolase |
| M. avium 104 | MAV_1428 | - | 0.0 | 54.52% (884) | hypothetical protein MAV_1428 |
| M. smegmatis MC2 155 | MSMEG_5002 | - | 0.0 | 61.09% (884) | hypothetical protein MSMEG_5002 |
| M. thermoresistible (build 8) | TH_1853 | - | 0.0 | 59.16% (884) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4005 | - | 0.0 | 53.45% (883) | hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4435|M.vanbaalenii_PYR-1 MKLHRLALTNYRGITHRDIEFPDRGVVVVSGPNEAGKSSMLEALDLLLES
Mflv_2256|M.gilvum_PYR-GCK MKLHRLVLTNYRGITHRDIEFPDRGVVVVSGANEVGKSSMLEALDLLLES
MSMEG_5002|M.smegmatis_MC2_155 MKLHRLVLTNYRGITHREIEFPDHGVVVVSGANEIGKSSMIEALDLLIEA
TH_1853|M.thermoresistible__bu MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHA
MMAR_4142|M.marinum_M MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MUL_4005|M.ulcerans_Agy99 MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MLBr_01120|M.leprae_Br4923 MKLHRLALTNYRGTARREIEFPDRGVILVCGANEIGKSSMIEALDLLLEF
Mb1309|M.bovis_AF2122/97 MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
Rv1278|M.tuberculosis_H37Rv MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
MAV_1428|M.avium_104 MKLHRLTLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEA
MAB_1421|M.abscessus_ATCC_1997 MKLHRLSVTNYRGITHRDITFPERGVVVVGGANEVGKTSMIEALDLLIES
*:**** :***** ::*:: **::**::* *.** **:**:******:.
Mvan_4435|M.vanbaalenii_PYR-1 KDRSSKKEVKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKRPETELTV
Mflv_2256|M.gilvum_PYR-GCK KDRSNKKEIKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKKPETELTV
MSMEG_5002|M.smegmatis_MC2_155 KDRSSKKEVKQVKPTHADVGAEVSAEISTGPYRFLYRKRFHKRAETQLTI
TH_1853|M.thermoresistible__bu KDRSTKKEVKQVKPTHADVGAEITAEISTGPYRFVYHKRFHKKCATQLTI
MMAR_4142|M.marinum_M KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MUL_4005|M.ulcerans_Agy99 KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MLBr_01120|M.leprae_Br4923 RDRSTKKEVKQVKPANADIGSEVCAEISSGTYRFVYRKRFNKKCETALTV
Mb1309|M.bovis_AF2122/97 KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
Rv1278|M.tuberculosis_H37Rv KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
MAV_1428|M.avium_104 KDRSTKKEVKQVKPTHSDVGAEVSAEISCGPYRFVYRKRFHKKCETELTV
MAB_1421|M.abscessus_ATCC_1997 KDRSTKKDVKQVKPTFADVGSEVEAEISCGPYRFVYRKRFHKRAETHLTV
:*** **::*****: :*:*:*: **** *.***:*:***:*: * **:
Mvan_4435|M.vanbaalenii_PYR-1 LTPRREQLTGDEAHERVRAILAESVDLDLWQAQRVLQSAPTSAADLSGCN
Mflv_2256|M.gilvum_PYR-GCK VAPRRQQFTGDEAHERVRAMLAETVDLDLWQAQRVLQSAPTTAADLSACD
MSMEG_5002|M.smegmatis_MC2_155 LSPVREQLSGDEAHQRVLAMLAETVDTDLWQAQRVLQASSTAPVDLSGSD
TH_1853|M.thermoresistible__bu LAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQAGSTAPVDLSGCD
MMAR_4142|M.marinum_M LAPRREQLTGDEAHERVRAILAETVDTELWRAQRVLQAASTTAVDLSSCD
MUL_4005|M.ulcerans_Agy99 LAPRREQLTGDEAHERVRAILAETVDTKLWRAQRVLQAASTTAVDLSSCD
MLBr_01120|M.leprae_Br4923 LAPHREQLTGDEAHERVRAMLAETVDNDLWHAQRVLQAASTAAVDLSGCD
Mb1309|M.bovis_AF2122/97 LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
Rv1278|M.tuberculosis_H37Rv LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
MAV_1428|M.avium_104 ITPYREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQAASTAAVDLSGCD
MAB_1421|M.abscessus_ATCC_1997 IEPRREQLSGDEAHQRVLDMLDQSIDMNLWKAQRVLQSAGAGVLDLSSSD
: * *::::*****:*. :* :::* .**::*****:. : ***..:
Mvan_4435|M.vanbaalenii_PYR-1 ALSRALDVVAGEVD-DVSATGAGNVESLLVDRVEEEYRRYFTSTGRATGE
Mflv_2256|M.gilvum_PYR-GCK ALSRALDVVAGEVD-DDPAPG-GAVDTLLVDRIDEEYRRYFTLTGKPTGE
MSMEG_5002|M.smegmatis_MC2_155 ALARALDVAAGEA---VSLSG---DEPLLIERIEGEYQRYFTATGRPTGE
TH_1853|M.thermoresistible__bu ALSRALDAVAGEA---VQTSG---TEPLLIDRIDAEYRKYFTATGRPTGE
MMAR_4142|M.marinum_M ALSRALDIAAAHSATDVALSG---AEPVLIERIDTEYSRYFTPTGRPTGE
MUL_4005|M.ulcerans_Agy99 ALSRALDIAAAHSATDVALSG---AEPVLIERIDAEYSRYFTPTGRPTGE
MLBr_01120|M.leprae_Br4923 ALSRALDLAAGDHA---ELSG---TEPLLIERIEAEYRRYFTSTGRPTGE
Mb1309|M.bovis_AF2122/97 ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
Rv1278|M.tuberculosis_H37Rv ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
MAV_1428|M.avium_104 ALSRALDVAAGDSG---GLCG---TEPLLIERIDAEYARYFTPTGRPTGE
MAB_1421|M.abscessus_ATCC_1997 ALTRALDLAAGQS---VALSG---SEPDLVERIDAEYALYFTGTGRPTGE
**:**** .*.. * :. *::*:: ** *** **:.***
Mvan_4435|M.vanbaalenii_PYR-1 WAAATARLRAADEEVARCAAAMAEVDEAVRRHAALTTDMAQLAVETASAA
Mflv_2256|M.gilvum_PYR-GCK WAAATKRLRDADEQVARCAAAVAEVDEAVRRHAALTADLAVLSAERVTAA
MSMEG_5002|M.smegmatis_MC2_155 WAAAVKRLQAADAEVARCAAAVAEVDDAVHRHQELSAEVSRLAGECEQAT
TH_1853|M.thermoresistible__bu WLAATKRLQAADEQVARCAARVAEVEDAVRRHATLTESLAELEDGRRTAD
MMAR_4142|M.marinum_M WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPQLAAAG
MUL_4005|M.ulcerans_Agy99 WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPKLAAAG
MLBr_01120|M.leprae_Br4923 WAVAISRLSDAETAVGECAAAVAEVDDRVRRHAVLTERVAGLAQQRFAAG
Mb1309|M.bovis_AF2122/97 WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
Rv1278|M.tuberculosis_H37Rv WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
MAV_1428|M.avium_104 WAAAIARLADAEAAVAECAAAVAEVDERVSRHAALTEQVADLSQRRIAAG
MAB_1421|M.abscessus_ATCC_1997 WARAGARLTAAEDALASARAAMAEVDQQVREHDELTQELASVIADRAEVN
* : ** *: :. . * ::**:: : .* *: : :
Mvan_4435|M.vanbaalenii_PYR-1 ERLQSARNAAAAVAVLQGELDQATARAEAARSVHAASKAALAQRRRARAD
Mflv_2256|M.gilvum_PYR-GCK AHLESAAQAEKKVAALRADLDRATARAEAATSTHTASQSALTERRRCRAD
MSMEG_5002|M.smegmatis_MC2_155 QRLTATRTAADAVDALRQQLKEAQVVAEAAHVTHAASVAALTERRRMRAE
TH_1853|M.thermoresistible__bu AQLAAAREAAEAVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAE
MMAR_4142|M.marinum_M SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MUL_4005|M.ulcerans_Agy99 SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MLBr_01120|M.leprae_Br4923 PRLAVAQAAADKVAVLTRQAREAELVAAAATATNAAAVAAHTSRLRLLAE
Mb1309|M.bovis_AF2122/97 LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
Rv1278|M.tuberculosis_H37Rv LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
MAV_1428|M.avium_104 PRVTAARQAADRIAELTAQRREAQLVAEAAAATKAAAAQAHSGRLQLLAD
MAB_1421|M.abscessus_ATCC_1997 RRLAPLEEASQAVTTLVQQHDNAVVVAEAAQAAAVAAQTKRDERAQLVAD
:: * : : : .* : * . *: * :
Mvan_4435|M.vanbaalenii_PYR-1 LDERSATVTSLQTESDTAADELDTANEMQVAAEEAAGKARSALAACQERV
Mflv_2256|M.gilvum_PYR-GCK IDDRTATITRLQAESAVATDELDTAAQMKVAADEAAEKARLALTAGQERV
MSMEG_5002|M.smegmatis_MC2_155 IDERAATITELQAALVTAAEEAETAREVVTAAEEEAERAKAAVADHEARV
TH_1853|M.thermoresistible__bu IEERTAAVAALQPEVDAALEAEATAREVQQEADTAAERAREAADAARERV
MMAR_4142|M.marinum_M IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MUL_4005|M.ulcerans_Agy99 IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MLBr_01120|M.leprae_Br4923 IDTRAVVLAATQDEAQEAVDAVSTMRADAEASDAAVEESTEALMAAQQRA
Mb1309|M.bovis_AF2122/97 IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
Rv1278|M.tuberculosis_H37Rv IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
MAV_1428|M.avium_104 IDTRAAAVTQTHAQVQQAAADHAVAQADAQACDTALQHATEALAELERRV
MAB_1421|M.abscessus_ATCC_1997 IRARRVSIDMLAEQLSATAEAHGTAQQVCEAAEAAAAQATESVDAARVQL
: * : : .: .: . :
Mvan_4435|M.vanbaalenii_PYR-1 DAARVAVQRLADREEADRLTGRIATIERHGRELEAVQRDLTAITLTDALL
Mflv_2256|M.gilvum_PYR-GCK DAARGAVQRLADREEVDRLAGRIATIERHQRELDAVSGELAAIALTDPLM
MSMEG_5002|M.smegmatis_MC2_155 DAARAAVERLSDRDEADRLDMRLAKIDAATRELQAVTDELKTITLDDTAM
TH_1853|M.thermoresistible__bu DTARQAVQRLADRAERDTLADRLRRIDAAATELARVDGELATLTVTEAAL
MMAR_4142|M.marinum_M EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MUL_4005|M.ulcerans_Agy99 EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MLBr_01120|M.leprae_Br4923 DIARSTVDQLVDRQEADRLSTRLAKIDAIQGERDLICAELSAVTLTEQLL
Mb1309|M.bovis_AF2122/97 ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
Rv1278|M.tuberculosis_H37Rv ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
MAV_1428|M.avium_104 QEAQRTVERSAGREEADRLAARLDKIDAIQRDRERISAELSTIAVTEELL
MAB_1421|M.abscessus_ATCC_1997 EAARGTLDRALARDEVDGLAARVSRIDLTNRQLASVGAELSSLVITAQSL
: *: :::: : : * *: * : : :* :.: :
Mvan_4435|M.vanbaalenii_PYR-1 ADIETAAAAVERATAAVEQTSAHIEVTAAADVEVRIGDADMTLRAGDTWA
Mflv_2256|M.gilvum_PYR-GCK TAIEKAAAVVDRATAAVAYASARMELVAAADLEISVDGSTVTLNAGDTWS
MSMEG_5002|M.smegmatis_MC2_155 RAIEKAALAVERAAGQAELASARIELVAQNGLDVRVDDATVALQAGAEWS
TH_1853|M.thermoresistible__bu RQIEAAELAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWT
MMAR_4142|M.marinum_M KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVGGQRVQLSAGSSWS
MUL_4005|M.ulcerans_Agy99 KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVDGQRVQLSAGLSWS
MLBr_01120|M.leprae_Br4923 QRIENAAAIVDRTGEQLKLISAAVEFTATADIEISVGQQRVSLEAGQSWS
Mb1309|M.bovis_AF2122/97 SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
Rv1278|M.tuberculosis_H37Rv SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
MAV_1428|M.avium_104 RRIEDAAAAVDRIGDQLASTSAAVEFTAVADIHLVIGDRQVSLPAGQSWS
MAB_1421|M.abscessus_ATCC_1997 GAIETAARAVGMAEAALETASAQVELRALVDVDIAVNGEQLRVAAGDRWS
** * * ** :*. * .:.: :. : : ** *:
Mvan_4435|M.vanbaalenii_PYR-1 AAVGTATGIDLPGVLSVQVIPGASAAATAAALDTAAARLADALRAAGVDD
Mflv_2256|M.gilvum_PYR-GCK AGVSADTGVDVAGVLSLRITPGASASATQSELDDATAALSDALAQAGVAD
MSMEG_5002|M.smegmatis_MC2_155 VSTTTRTEIDVPGVLSVRVVPGTPAAETQARLDDAQAVLTAALQAVGAES
TH_1853|M.thermoresistible__bu AGATAPTEIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVAD
MMAR_4142|M.marinum_M MTATGPAEVEVPGVLTARITQGATALEAQAKYVAAQEELAVALAAGGVAT
MUL_4005|M.ulcerans_Agy99 MTATGPAEVEVPGVLTARIIQGATALEAQAKYVAAQEELAVALAAGGVAT
MLBr_01120|M.leprae_Br4923 TTATGPTEVEVLGVLTACVIPGATALDAQSKYVAAQEELSVALADGGVVD
Mb1309|M.bovis_AF2122/97 VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
Rv1278|M.tuberculosis_H37Rv VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
MAV_1428|M.avium_104 ITAVGPTAVEVPGVLTARVTPGATTLDVQAKHAAAQQELAAALTAGAVAD
MAB_1421|M.abscessus_ATCC_1997 SAATDTIEITAPGVAVARIIPGPNAAQLRDKLDTARQTLSGALADAGVAD
. : *: : *. : * *: ** .
Mvan_4435|M.vanbaalenii_PYR-1 VEAARALDRRRHELSAAGRQIRAILEALAADDSVDQLRARLADLQARTP-
Mflv_2256|M.gilvum_PYR-GCK LAAARALDAHRQQLCGARRQVSAILDALTAEDSVADLQTRLTAVQARIP-
MSMEG_5002|M.smegmatis_MC2_155 VDVARALDARRRELLGSRDRLRATLDALVGDDDIARLRDRLAALRAGQT-
TH_1853|M.thermoresistible__bu VASARSQVERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAAS-
MMAR_4142|M.marinum_M LAEARSVEQRRRELLGRRDQLSATLAGLCGDEQVDQLRCRLAQLQASQP-
MUL_4005|M.ulcerans_Agy99 LAEARSVEQRRRELLGRRDQLNATLAGLCGDEQVDQLRCRLAQLQASQP-
MLBr_01120|M.leprae_Br4923 LAAARCANQRRRELQSSLDQLSAALAGVCGDDQIDQLRARLEQLRDGYP-
Mb1309|M.bovis_AF2122/97 LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
Rv1278|M.tuberculosis_H37Rv LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
MAV_1428|M.avium_104 LGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDELRSRLARLRAEHPE
MAB_1421|M.abscessus_ATCC_1997 VGEAQKQFERRTELNAERDRLTALLDGLMGPESLEALREKLSRLRELVP-
: *: * :* . * : .: . : : *: :* : .
Mvan_4435|M.vanbaalenii_PYR-1 --AEEGLFDTDTRGSLDPAAQRLELVEATAAHQQAIRDCETHRKVAEEAA
Mflv_2256|M.gilvum_PYR-GCK --AADGLFDTDA-AILDPAAQRLELIEATAAHQDAIRDCETHRKVADQAG
MSMEG_5002|M.smegmatis_MC2_155 --DDGGLFDVEGPADID--TARAQLAADVAAHREAVAHCETARKAVAVAA
TH_1853|M.thermoresistible__bu --DDTGELGVDD--------AQAELTAAERAYQQAHTDCETHRKAAVLAA
MMAR_4142|M.marinum_M --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLALAAS
MUL_4005|M.ulcerans_Agy99 --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLAVAAS
MLBr_01120|M.leprae_Br4923 --GEPDLLAVDI------GSARAELEAAETVRAAVDFEREVCRRTAAAAN
Mb1309|M.bovis_AF2122/97 --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
Rv1278|M.tuberculosis_H37Rv --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
MAV_1428|M.avium_104 QPAAPTGGAADL------AAARTELEALAQARACASAECVTRRQAATAAA
MAB_1421|M.abscessus_ATCC_1997 --EATGLWDAIDP-----AQARAEVARLVGEVERLQAEEVTHRRAVQTAG
. : :: . *: . *
Mvan_4435|M.vanbaalenii_PYR-1 KLSAKRGLHAARLLEKLQAAQAELAAAGARLAEQRAATSDDELAVKAEAD
Mflv_2256|M.gilvum_PYR-GCK KLVAQRELNAARIAQKLQSAQHELTTIAARLAEQRASVGDEELALKTDAD
MSMEG_5002|M.smegmatis_MC2_155 ARDTEKSTRLSVLREKLTAAQTELTTCSARLEAQRAGTPDEALALKVQAD
TH_1853|M.thermoresistible__bu RRLAEKSQTAAALREKLTAARTELDTAAARLAAQRADVDDETLVVRAAAH
MMAR_4142|M.marinum_M RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MUL_4005|M.ulcerans_Agy99 RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MLBr_01120|M.leprae_Br4923 CRLVETSARANFLLKKAETQRAELDQDIDQLAQQRASVSDEDLASAAEAG
Mb1309|M.bovis_AF2122/97 RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
Rv1278|M.tuberculosis_H37Rv RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
MAV_1428|M.avium_104 ARLAETATAATVLQNRLDTLRAELDAATGRLAAERASVGDEELAASADAA
MAB_1421|M.abscessus_ATCC_1997 QQLAEKAAEAMAAREKHAARAEELAAAEQRLAHVRSSASDDLLTERHERA
.: . *: :* *: . * *.
Mvan_4435|M.vanbaalenii_PYR-1 AEAAAAAEAAVARVGAELAGHEPEAVAAALVDAERAAAEVGARHHEVGEA
Mflv_2256|M.gilvum_PYR-GCK AETAAKAVAAVAELRDELARHHPDAVVAALAEAERALATVTARRDEAVEA
MSMEG_5002|M.smegmatis_MC2_155 DEQAKATAARVATLRDELDRSAPDSVLAELADAQRHAQSVQTRHDAATEG
TH_1853|M.thermoresistible__bu GEEAERAAVRVAQLNAELSAAQPDQVAAALDTAARHAETVHAEHRRTADA
MMAR_4142|M.marinum_M LHVLQASQRRLAELAEVLDAAEPEAVAAELREAAEIAQSLDERHDAVVAA
MUL_4005|M.ulcerans_Agy99 LHVLQASQRRLAELTEVLDAAEPEAVAAEAREAAEIAQSLGERHDAVVAA
MLBr_01120|M.leprae_Br4923 LRAVQIAEQRVAKLTEELVAAEPEAVTAELVAATAAAESLRDQHEDAAGA
Mb1309|M.bovis_AF2122/97 LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
Rv1278|M.tuberculosis_H37Rv LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
MAV_1428|M.avium_104 LRAEQAAERRVAELADALAAASPDSVAAELADATQESESLRERYEEAAGA
MAB_1421|M.abscessus_ATCC_1997 VQAADLTSRRVTDLVSQLAALEADRVRAELAEVSARAQALDRRHEATRDR
. : : : * .: * * . : . .
Mvan_4435|M.vanbaalenii_PYR-1 LREIAAQLKVYGTEGRKGGLDAAETERGRAEAEFVRVQRRARAAELLRSV
Mflv_2256|M.gilvum_PYR-GCK LREIAAQLKVFGTEGRKGNLDAAETERERAEAEFGRVQRRARAAQLLRTV
MSMEG_5002|M.smegmatis_MC2_155 LREVSAQLKVYGTEGRKGQLDEAETEREHANAEYLRVHRRARAAELLRSV
TH_1853|M.thermoresistible__bu LRELNAQLEVYGSEGRKGELDAAKAEREQAEAEFLRIGRLARAVKLLRET
MMAR_4142|M.marinum_M LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MUL_4005|M.ulcerans_Agy99 LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MLBr_01120|M.leprae_Br4923 LREISIELSVFGTEGRQGKLDTAEAEREHAISQHTQIGRRARAAQLLRSV
Mb1309|M.bovis_AF2122/97 LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
Rv1278|M.tuberculosis_H37Rv LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
MAV_1428|M.avium_104 LREVTIELSVFGSEGRQGKLDAAETEREHAASEHSQVGRRARAAQLLRSV
MAB_1421|M.abscessus_ATCC_1997 LRDISVRLEVFGRQGRQDQLDAAASEREYAATEFARIGAKARAVDTLRSV
*::: .*.*:* :**:. ** * :** * :.. :: ***. ** .
Mvan_4435|M.vanbaalenii_PYR-1 MGRHRDAMRQRYVDPFRGEVERLGRIVFGDSFEVDVDSSLCIGNRTLSGR
Mflv_2256|M.gilvum_PYR-GCK MGRHRDAMRQRYVDPFRTEVERLGRIVFGDTFEVDVDSELRIGHRTLSGR
MSMEG_5002|M.smegmatis_MC2_155 MTRHRDATRQRYVDPFRNEVQRLGRLVFGEDFEVDVDSKLRISTRTVSGR
TH_1853|M.thermoresistible__bu MLRHRDASRRRYVDPFRAEVERLGRIVFGDSFEVEIDSDLCIRSRTLAGR
MMAR_4142|M.marinum_M MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MUL_4005|M.ulcerans_Agy99 MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MLBr_01120|M.leprae_Br4923 MARHRDTTRLRYVEPYRTELQRLGRPVFGPTFEVDIDSDLRIRSRTLDGI
Mb1309|M.bovis_AF2122/97 MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
Rv1278|M.tuberculosis_H37Rv MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
MAV_1428|M.avium_104 MTRHRDTTRQRYVEPYRAELQRLGRPVFGPTFEVDIDSDLCIRSRTLNGI
MAB_1421|M.abscessus_ATCC_1997 MMRHRDGMRLRYVDPFRAELERLGRMVFGPTFEVDIDSDLSIRSRTLEGR
* **** * ***:*:* *:.**** *** ***::.:.* * **: .
Mvan_4435|M.vanbaalenii_PYR-1 TVPYESLSGGAKEQLGIVARLAGAALVAKEDSVPVVIDDALGFTDTERLT
Mflv_2256|M.gilvum_PYR-GCK TVPYESLSGGAKEQLGIVARLAGATLVASEDSVPVVIDDALGFTDADRLT
MSMEG_5002|M.smegmatis_MC2_155 TVPYESLSGGAKEQLAIVARLAGASLVAKEDTVPVIIDDALGFTDADRLT
TH_1853|M.thermoresistible__bu TVDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFTDAERLV
MMAR_4142|M.marinum_M TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MUL_4005|M.ulcerans_Agy99 TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MLBr_01120|M.leprae_Br4923 TVPFESLSGGAKEQLGILARFAGATLVAKEDNVPVVVDDALGFTDPDRLA
Mb1309|M.bovis_AF2122/97 TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
Rv1278|M.tuberculosis_H37Rv TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
MAV_1428|M.avium_104 TVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLA
MAB_1421|M.abscessus_ATCC_1997 TVPYESLSGGAKEQLGIVARLASAALVAPQDAVPVIIDDALGFTDSDRLE
** :*.*********.*:**:*.*:*** :* ***::********.:**
Mvan_4435|M.vanbaalenii_PYR-1 KMAEVFDAVAGDGQVIILTCSPQRYAGVRTAQHIELIAG-
Mflv_2256|M.gilvum_PYR-GCK KMAEVFDAVAGDGQVIILTCSPQRYADVRSARHIELVAG-
MSMEG_5002|M.smegmatis_MC2_155 KMGAVFDAVGGDGQVIVLTCSPDRYASVHGAHHIALTA--
TH_1853|M.thermoresistible__bu KMGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA--
MMAR_4142|M.marinum_M KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MUL_4005|M.ulcerans_Agy99 KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MLBr_01120|M.leprae_Br4923 KMGEMFDTVGAHGQVIVLTCSPDRYDGFTGAHRIDLNV--
Mb1309|M.bovis_AF2122/97 KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
Rv1278|M.tuberculosis_H37Rv KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
MAV_1428|M.avium_104 KMGQLFDSVGSHGQVIVLTCSPDRYDGVKGAHRIDLSA--
MAB_1421|M.abscessus_ATCC_1997 RMGEVFGAVGTETQVIVLTCSPDRYRAVTGAQRISLSA--
:*. :*.::. . ***:***** ** . *::* *