For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGEQGAKTLRGGKMEDVIFAGTS SRAPLGRAEVTLTIDNSDNALPIEYSEVSITRRMFRDGAGEYEINGSSCRLMDVQELLSDSGIGREMHVI VGQGKLSEILESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMSANLARLTDLTTELRRQLKPLGRQAE MARRAQTIQADLRDARLRLAADDLVTRKAEFDDTNQAETTLRREHDELTERMEARTLELDAHESAVADLS ERADAAQQRWFRLSALAERVSATVRIASERAQHLDAEPDFSAGPDPDELEAQADAVAEQEQLLLDELAES QARLESARAELGEREQAAAEAERAHMAAARAEADRREGLARLSGQVDTMRTRVDSVDETVARLTASIDEA GARAQQTQAEFETVQGRVAELDSGEVGLDEHHDRTVAALRLADERVTELQAAERAAERRVASLQARIDAL SVGLDRKDGAAWLKENRSGAGLFDSLANLVKVRPGHEAAIAAVLGAAADALAAENSGAARDALAALKESD GGRAAIVLGDWPARTPATGQLPAGAAWAVDLVDPAPRIQGAVTAMLGGVAVVGDLTAALELVAAQPELRA VTADGDLVGAGWVSGGSDRKPSTLEITSEVDKARAELVDAERQTGELSAALSGALAEQAARQDAAEQALA ALNESDAAISAIYEQLGRLGQDARAADDEWQRLIKQRDELEAGRNRTVEELAELESRLHNAQQEPMFDVE VVDRTEFTAAAEAARSAEVEARLAVRTAEERANAVRGRADSLRRAAVAEREARARAQRAREARVQAAAVA AAVAESGRLVAQRLADAVAVASRIRDEVAAERHVRAAALTKAREEVAELTARIAALTDSLHRDEVAKAQA ALRIEQLEQQVLEQFGIAVADLIAEYGPDVPLPPSELEMAEYEQAKERGEQVTAPAPMPYDRPTQERRAK RADKELRELGRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDSRILQVFTEAYMDVEREF TQVFSTLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKIKRLSLLSGGEKSLTAVAMLVAIFRARPSPFY VMDEVEAALDDVNLRRLISLFEQLRERSQLIVITHQKPTMEVADALYGVTMRGDGITTVISQRMRGQELV ASPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2175 | - | - | 100% (1194) | chromosome segregation protein SMC |
| M. vanbaalenii PYR-1 | Mvan_1098 | - | 1e-16 | 24.57% (867) | SMC domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4435 | - | 5e-16 | 25.72% (661) | hypothetical protein Mvan_4435 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2946c | smc | 0.0 | 75.69% (1197) | chromosome partition protein Smc |
| M. gilvum PYR-GCK | Mflv_4188 | - | 0.0 | 92.38% (1194) | chromosome segregation protein SMC |
| M. tuberculosis H37Rv | Rv2922c | smc | 0.0 | 75.86% (1197) | chromosome partition protein Smc |
| M. leprae Br4923 | MLBr_01629 | smc | 0.0 | 71.57% (1196) | putative cell division protein |
| M. abscessus ATCC 19977 | MAB_3246c | - | 0.0 | 74.28% (1151) | chromosome partition protein Smc |
| M. marinum M | MMAR_1785 | smc | 0.0 | 76.58% (1200) | chromosome partition protein Smc |
| M. avium 104 | MAV_3777 | smc | 0.0 | 79.33% (1190) | chromosome segregation protein SMC |
| M. smegmatis MC2 155 | MSMEG_2423 | smc | 0.0 | 82.93% (1195) | chromosome segregation protein SMC |
| M. thermoresistible (build 8) | TH_1649 | smc | 1e-134 | 92.40% (263) | PROBABLE CHROMOSOME PARTITION PROTEIN SMC |
| M. ulcerans Agy99 | MUL_2033 | smc | 0.0 | 76.25% (1200) | chromosome partition protein Smc |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2175|M.vanbaalenii_PYR-1 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
Mflv_4188|M.gilvum_PYR-GCK MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
MSMEG_2423|M.smegmatis_MC2_155 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAV_3777|M.avium_104 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Mb2946c|M.bovis_AF2122/97 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Rv2922c|M.tuberculosis_H37Rv MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MLBr_01629|M.leprae_Br4923 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
MAB_3246c|M.abscessus_ATCC_199 ----------------------------------------MDALTWVMGE
Mvan_2175|M.vanbaalenii_PYR-1 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
Mflv_4188|M.gilvum_PYR-GCK QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
MSMEG_2423|M.smegmatis_MC2_155 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDNALPIEYSEVSI
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI
MAV_3777|M.avium_104 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVTIDNSDNALPIEYSEVSI
Mb2946c|M.bovis_AF2122/97 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
Rv2922c|M.tuberculosis_H37Rv QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSI
MLBr_01629|M.leprae_Br4923 QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI
MAB_3246c|M.abscessus_ATCC_199 QGAKALRGGKMEDVIFAGTSSRAPLGRAEVTLTIDNSDHALPIEYSEVSI
Mvan_2175|M.vanbaalenii_PYR-1 TRRMFRDGAGEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
Mflv_4188|M.gilvum_PYR-GCK TRRMFRDGAGEYEINGSRCRLADVQELLSDSGIGREMHVIVGQGKLSEIL
MSMEG_2423|M.smegmatis_MC2_155 TRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSEIL
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MUL_2033|M.ulcerans_Agy99 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
MAV_3777|M.avium_104 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL
Mb2946c|M.bovis_AF2122/97 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
Rv2922c|M.tuberculosis_H37Rv TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEIL
MLBr_01629|M.leprae_Br4923 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQIL
MAB_3246c|M.abscessus_ATCC_199 TRRMFRDGAGEYEINGQTCRLMDVQELLSDSGIGREMHVIVGQGRLSQIL
Mvan_2175|M.vanbaalenii_PYR-1 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMSANLARLTDLTTELRR
Mflv_4188|M.gilvum_PYR-GCK ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
MSMEG_2423|M.smegmatis_MC2_155 ESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTELRR
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MUL_2033|M.ulcerans_Agy99 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
MAV_3777|M.avium_104 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR
Mb2946c|M.bovis_AF2122/97 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
Rv2922c|M.tuberculosis_H37Rv QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRR
MLBr_01629|M.leprae_Br4923 QSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRR
MAB_3246c|M.abscessus_ATCC_199 ESRPEDRRAFVEEAAGVLKHRKRKEKAVRKLESMAANLARLTDLTTELRR
Mvan_2175|M.vanbaalenii_PYR-1 QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVTRKAEFDDTNQAETT
Mflv_4188|M.gilvum_PYR-GCK QLKPLGRQAEMARRAQTIQADLRDARLRLAADDLVARKAEFDDTDQAETT
MSMEG_2423|M.smegmatis_MC2_155 QLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAETA
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MUL_2033|M.ulcerans_Agy99 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT
MAV_3777|M.avium_104 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDLVNRRGEREAIFEAEAA
Mb2946c|M.bovis_AF2122/97 QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
Rv2922c|M.tuberculosis_H37Rv QLKPLGRQAEAAQRAAAIQADLRDARLRLAADDLVSRRAEREAVFQAEAA
MLBr_01629|M.leprae_Br4923 QLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETM
MAB_3246c|M.abscessus_ATCC_199 QLKPLGRQAEVARRAATVQADLRDARLRLAADDLVSRRADFDGTNDAETA
Mvan_2175|M.vanbaalenii_PYR-1 LRREHDELTERMEARTLELDAHESAVADLSERADAAQQRWFRLSALAERV
Mflv_4188|M.gilvum_PYR-GCK LRREHDELTERLQERAAELDAHETAVEDLSERADAAQQRWFRLSALAERV
MSMEG_2423|M.smegmatis_MC2_155 LRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAERV
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M MRREHDEAAARLTVAAEELAAHEAALAELTSRAESVQHTWFGLSALAERV
MUL_2033|M.ulcerans_Agy99 MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV
MAV_3777|M.avium_104 MRREHDEASARLAVASEELAAHEKALGELSGRAESVQQTWFALSALAERV
Mb2946c|M.bovis_AF2122/97 MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
Rv2922c|M.tuberculosis_H37Rv MRREHDEAAARLAVASEELAAHESAVAELSTRAESIQHTWFGLSALAERV
MLBr_01629|M.leprae_Br4923 MRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERV
MAB_3246c|M.abscessus_ATCC_199 LRKEHAEITDRLEVATALLAEHETALGELLPQAELAQQTWFRLSALAERV
Mvan_2175|M.vanbaalenii_PYR-1 SATVRIASERAQHLDAEPDFSAGPDP---DELEAQADAVAEQEQLLLDEL
Mflv_4188|M.gilvum_PYR-GCK SATVRIASERAQHLDGDPDFSAGPDP---DELEAQADAVAEQEQQLLDEL
MSMEG_2423|M.smegmatis_MC2_155 GATVRIATDRAQMLDSEPEMSSGRDP---DALEAEAEEVAELEAQLLDEL
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MUL_2033|M.ulcerans_Agy99 GTTVRIANERAQHLDVEPVTNSDTDP---DALDAEAEQVAIAEQQLLVEL
MAV_3777|M.avium_104 AATVRIASERAQHLDLGPVTAGDTDP---DALDAEAERVAAAEQQLLAEL
Mb2946c|M.bovis_AF2122/97 DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
Rv2922c|M.tuberculosis_H37Rv DATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVAVAEQQLLAEL
MLBr_01629|M.leprae_Br4923 SATIRIAGERAYHLDVDPATPSDTDP---DVLEAEAQQMEVAEQQLLAEL
MAB_3246c|M.abscessus_ATCC_199 SATVRIAGERASHLDEVAAAPTGPDP---EELEAQAERVAEQERLLIAQL
Mvan_2175|M.vanbaalenii_PYR-1 AESQARLESARAELGEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
Mflv_4188|M.gilvum_PYR-GCK AESQERLEAAREELAEREQAAAEAERAHMAAARAEADRREGLARLSGQVD
MSMEG_2423|M.smegmatis_MC2_155 SEARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVD
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MUL_2033|M.ulcerans_Agy99 AEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVE
MAV_3777|M.avium_104 AAARSRLETARAELAEREREAAEADRAHMAAVRAEADRREGLARLAGQVE
Mb2946c|M.bovis_AF2122/97 DAARARLDAARAERADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
Rv2922c|M.tuberculosis_H37Rv DAARARLDAARAELADRERRAAEADRAHLAAVREEADRREGLARLAGQVE
MLBr_01629|M.leprae_Br4923 AVARTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVE
MAB_3246c|M.abscessus_ATCC_199 ETVTEQLATAKAELSARESAVAQAQRQHMAAVAAEADRREGLARLTGQVD
Mvan_2175|M.vanbaalenii_PYR-1 TMRTRVDSVDETVARLTASIDEAGARAQQTQAEFETVQGRVAELDSGEVG
Mflv_4188|M.gilvum_PYR-GCK TMRTRVESVDETVARLTANIDDAAARAQLTQAEFETVQARVGELDAGEVG
MSMEG_2423|M.smegmatis_MC2_155 TMRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVG
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MUL_2033|M.ulcerans_Agy99 TMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVG
MAV_3777|M.avium_104 TMRARVESIDDSVARLSERIEAAAARAQQAKAEFETVQGRVGELDQGEVG
Mb2946c|M.bovis_AF2122/97 TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
Rv2922c|M.tuberculosis_H37Rv TMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVG
MLBr_01629|M.leprae_Br4923 TMRARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVH
MAB_3246c|M.abscessus_ATCC_199 TMRTRLESIDGQAQRLTESIVEATVRGEAAQTEFDTVKARVAELDQGEVG
Mvan_2175|M.vanbaalenii_PYR-1 LDEHHDRTVAALRLADERVTELQAAERAAERRVASLQARIDALSVGLDRK
Mflv_4188|M.gilvum_PYR-GCK LDEHHDRSVAALRLADERVAELLAAERAAERQVASLQARIDALSVGLDRR
MSMEG_2423|M.smegmatis_MC2_155 LDEHHDRTVAALRLADERVAELQAAERAAERQVASLRARIEALSVGLDRR
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIEALSVGLDRK
MUL_2033|M.ulcerans_Agy99 LDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRK
MAV_3777|M.avium_104 LDEHHERTVAALRLADERVAELQAAERDAERKVASLRARIDALAVGLERK
Mb2946c|M.bovis_AF2122/97 LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
Rv2922c|M.tuberculosis_H37Rv LDEHHERTVAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRK
MLBr_01629|M.leprae_Br4923 LDEQHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERK
MAB_3246c|M.abscessus_ATCC_199 LDEHHERSISSLSIANERVAELQSAERQAERQIASLKARIDALAIGLERK
Mvan_2175|M.vanbaalenii_PYR-1 DGAAWLKENRSGAGLFDSLANLVKVRPGHEAAIAAVLGAAADALAAENSG
Mflv_4188|M.gilvum_PYR-GCK DGAAWLQENHSGAGLFGSIANLVKVRAGHEAAIAAMLGAAADALAAEDFG
MSMEG_2423|M.smegmatis_MC2_155 DGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENFG
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MUL_2033|M.ulcerans_Agy99 DGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFG
MAV_3777|M.avium_104 DGTAWLTENHSGAGILGPMAKLVKVRSGYEAAVAAVLGSAADALAADGLG
Mb2946c|M.bovis_AF2122/97 DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
Rv2922c|M.tuberculosis_H37Rv DGAAWLAHNRSGAGLFGSIAQLVKVRSGYEAALAAALGPAADALAVDGLT
MLBr_01629|M.leprae_Br4923 DGAAWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLG
MAB_3246c|M.abscessus_ATCC_199 DGSAWLAENRSGAGIFGSIAQLVKVRPGYQGAIATAMGPAADAVAAENPA
Mvan_2175|M.vanbaalenii_PYR-1 AARDALAALKESDGGRAAIVLGDWP---ARTPATG-QLPAGAAWAVDLVD
Mflv_4188|M.gilvum_PYR-GCK AARAAVAALKESDGGRAALVLGDWP---AQEAVTG-QLPAGAAWAVDLVE
MSMEG_2423|M.smegmatis_MC2_155 AAAAAVAALKESDGGRAAIVLGDWN---AIGSSPQAALPPGATWATDLVS
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M AARSAVTALKQADGGRAALVLGDWPDANDHRAAG--GLPSGTLWALDLIE
MUL_2033|M.ulcerans_Agy99 AARSAVTALKQADGGRAALVLGDWPDAHDHRAAG--GLPSGTLWALDLIE
MAV_3777|M.avium_104 AARSALGALKQADGGRAALVLGDWP--ADPPAPQ--PAPAGALWALDLID
Mb2946c|M.bovis_AF2122/97 AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
Rv2922c|M.tuberculosis_H37Rv AAGSAVSALKQADGGRAVLVLSDWPAPQAPQSASGEMLPSGAQWALDLVE
MLBr_01629|M.leprae_Br4923 AARSALTALKEADAGRATLVLADWLADAGPACVT--GLPDGAQRALDLIE
MAB_3246c|M.abscessus_ATCC_199 AAHEAVKALKSSDGGRAAIVFGDWPAHTGARPAVT--LPPGAHWANDLVE
Mvan_2175|M.vanbaalenii_PYR-1 PAPRIQGAVTAMLGGVAVVGDLTAALELVAAQPELRAVTADGDLVGAGWV
Mflv_4188|M.gilvum_PYR-GCK PADRVRGAVTAMLSGVAVVENLTAALDLVAAQPRLRAVTADGDLVGAGWV
MSMEG_2423|M.smegmatis_MC2_155 VPDRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWV
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MUL_2033|M.ulcerans_Agy99 VPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWV
MAV_3777|M.avium_104 APERLRGAITAMLSGVAVVDDLDRALALVAEHPRLRAVTLDGDLVGAGWV
Mb2946c|M.bovis_AF2122/97 SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
Rv2922c|M.tuberculosis_H37Rv SPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPELRAVTVDGDLVGAGWV
MLBr_01629|M.leprae_Br4923 APPWLQGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWV
MAB_3246c|M.abscessus_ATCC_199 APQRLAAAVSAMLASVVVVDELGAAIDVVLANPLLRAVTIDGDRVGAGWV
Mvan_2175|M.vanbaalenii_PYR-1 SGGSDRKPSTLEITSEVDKARAELVDAERQTGELSAALSGALAEQAARQD
Mflv_4188|M.gilvum_PYR-GCK SGGSDRKPSTLEIQSEVDRARSELVDAERRTGELSAALSGALAEQAARQD
MSMEG_2423|M.smegmatis_MC2_155 SGGSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQD
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M SGGSDRKPSTLEITSEIDKARSELAAAEVRVAELGAALSGALTDQTARQD
MUL_2033|M.ulcerans_Agy99 SGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQD
MAV_3777|M.avium_104 SGGSDRKLSTLEVTSEIDKASAELAAAEAQVAQLSAALSGALAEQAARQD
Mb2946c|M.bovis_AF2122/97 SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSAGQD
Rv2922c|M.tuberculosis_H37Rv SGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTEQSARQD
MLBr_01629|M.leprae_Br4923 SGGSGRRLSTLEVTSEIDKAGAELAAAEAHMAQLNAALSGALSEQVAHSD
MAB_3246c|M.abscessus_ATCC_199 AGGSDKKQSTLEVQAAIEAAREELRATETQVGEISAALAGALAEQTARQD
Mvan_2175|M.vanbaalenii_PYR-1 AAEQALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIKQRDELEAG
Mflv_4188|M.gilvum_PYR-GCK AAEHALAALNESDAAISAIYEQLGRLGQDARAADDEWQRLIRQRDEMEAG
MSMEG_2423|M.smegmatis_MC2_155 AAEQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAG
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MUL_2033|M.ulcerans_Agy99 AAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVG
MAV_3777|M.avium_104 SAEQALAALNESDSAISGMYEQLGRLGQEARTSEDEWSRLLRQREELEAG
Mb2946c|M.bovis_AF2122/97 AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
Rv2922c|M.tuberculosis_H37Rv AAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAV
MLBr_01629|M.leprae_Br4923 ATEQALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEAR
MAB_3246c|M.abscessus_ATCC_199 TAEQALAALNESDAAISAVYEQLGRVGQEVRAAAEEVKKLTLQRDQLERG
Mvan_2175|M.vanbaalenii_PYR-1 RNRTVEELAELESRLHNAQQEP-MFDVEV---VDRTEFTAAAEAARSAEV
Mflv_4188|M.gilvum_PYR-GCK RNRTVSELAELELRLQNAQREP-MFDAEV---VDRTEFTAAAEAARSAEV
MSMEG_2423|M.smegmatis_MC2_155 RTKTVEELRELESRLSNAEQTP-MFDIEP---VDRQETVAAAEAARAVEV
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MUL_2033|M.ulcerans_Agy99 RTQTLEEVLELESRLRNAQESQHVQAAEP---VDRQEIAAAAESARAIEV
MAV_3777|M.avium_104 RTQTVAEVTELENRLRNAQETPQEPAAEP---VNRQQIAAATDAARSAEV
Mb2946c|M.bovis_AF2122/97 RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
Rv2922c|M.tuberculosis_H37Rv RTQTLDDVIQLETQLRKAQETQRVQVAQP---IDRQAISAAADRARGVEV
MLBr_01629|M.leprae_Br4923 RVSILEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEV
MAB_3246c|M.abscessus_ATCC_199 RATTLEELAEVESRLRNAEEAPNLFDDEP---LDRDDMAIELEEARSVEI
Mvan_2175|M.vanbaalenii_PYR-1 EARLAVRTAEERANAVRGRADSLRRAAVAEREARARAQRAREARVQAAAV
Mflv_4188|M.gilvum_PYR-GCK EARLSVRTAEERANAVRGRADSLRRAAVAEREARVRAQRAREARVHAAAV
MSMEG_2423|M.smegmatis_MC2_155 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARV
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M EARLTVRTAEERANALRGRADSLRRAAAAEREARVRAELARAVRLRSAAV
MUL_2033|M.ulcerans_Agy99 EARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAV
MAV_3777|M.avium_104 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQAREARLRAAAV
Mb2946c|M.bovis_AF2122/97 EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
Rv2922c|M.tuberculosis_H37Rv EARLAVRTAEERANAVRGRADSLRRAAAAEREARVRAQQARAARLHAAAV
MLBr_01629|M.leprae_Br4923 EALLAVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAV
MAB_3246c|M.abscessus_ATCC_199 EARLAVRTSEERVNSVRGKADSLRRAAVAEREARARAARAAAARMRAAAV
Mvan_2175|M.vanbaalenii_PYR-1 AAAVAESGRLVAQRLADAVAVASRIRDEVAAERHVRAAALTKAREEVAEL
Mflv_4188|M.gilvum_PYR-GCK AAAVAESGRAVAQRLADAVSVASRIRDEVAAERQVRAGALTKAREEVNEL
MSMEG_2423|M.smegmatis_MC2_155 AAAVSECGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTAL
TH_1649|M.thermoresistible__bu --------------------------------------------------
MMAR_1785|M.marinum_M AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MUL_2033|M.ulcerans_Agy99 AAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSL
MAV_3777|M.avium_104 AAAVADSGRLLATRLNAVVAAASRIRDALAAERQQRATAMTAVRDEVNAL
Mb2946c|M.bovis_AF2122/97 AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
Rv2922c|M.tuberculosis_H37Rv AAAVADCGRLLAGRLHRAVDGASQLRDASAAQRQQRLAAMAAVRDEVNTL
MLBr_01629|M.leprae_Br4923 AAAVTDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTL
MAB_3246c|M.abscessus_ATCC_199 AAAVAESGRMVAARLEHVVAAASARRDELSATRAQHTSAIGAVRDQVREL
Mvan_2175|M.vanbaalenii_PYR-1 TARIAALTDSLHRDEVAKAQAALRIEQLEQQVLEQFGIAVADLIAEYGPD
Mflv_4188|M.gilvum_PYR-GCK TARITALTDALHRDEVAKAQAALRIEQLEQQVLEQFGMAVADLVAEYGPD
MSMEG_2423|M.smegmatis_MC2_155 NNRINTLTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQ
TH_1649|M.thermoresistible__bu -------------------------------------MSADDLIAEYGPH
MMAR_1785|M.marinum_M SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MUL_2033|M.ulcerans_Agy99 SARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPD
MAV_3777|M.avium_104 SARVAALTDSLHRDEVANAQAALRIEQLEQMVLEQFGMAPADLIAEYGPH
Mb2946c|M.bovis_AF2122/97 SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
Rv2922c|M.tuberculosis_H37Rv SARVGELTDSLHRDELANAQAALRIEQLEQMVLEQFGMAPADLITEYGPH
MLBr_01629|M.leprae_Br4923 RVRLATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQ
MAB_3246c|M.abscessus_ATCC_199 TQAQTRLTDALHRDEVAKAQAALRIEQLSEQVLEQFGMAADDLIAEYGPH
:: **::****.
Mvan_2175|M.vanbaalenii_PYR-1 VPLPPSELEMAEYEQAKERGEQVTAPAPMPYDRPTQERRAKRADKELREL
Mflv_4188|M.gilvum_PYR-GCK VALPPSELEMAEYEQARERGEQVTAPAPMPYDRPTQERRAKRAERELKEL
MSMEG_2423|M.smegmatis_MC2_155 VALPPSELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAEL
TH_1649|M.thermoresistible__bu VPLPPTELEMAEYEQALERGEQVTKPAPMPYDRATQERRAKRAERELAEL
MMAR_1785|M.marinum_M VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MUL_2033|M.ulcerans_Agy99 VALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTEL
MAV_3777|M.avium_104 IALPPSELEMAEYEQAKERGEQVFAPAPIPFDRPTQERRAKRAERELAEL
Mb2946c|M.bovis_AF2122/97 VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
Rv2922c|M.tuberculosis_H37Rv VALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKRAERALAEL
MLBr_01629|M.leprae_Br4923 VALLPTELEMAEFQQARERGEQVTSPAPMPYDRATQERRAKRAERELAEL
MAB_3246c|M.abscessus_ATCC_199 IELPPSQQEIDEYEQARERGEQVSAPLPMPFDRDTQERRAKRAEKDLREL
: * *:: *: *::** ****** * *:*:** **:******:: * **
Mvan_2175|M.vanbaalenii_PYR-1 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDSRILQVF
Mflv_4188|M.gilvum_PYR-GCK GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIAEVDTRILQVF
MSMEG_2423|M.smegmatis_MC2_155 GRVNPLALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVF
TH_1649|M.thermoresistible__bu GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVIADVDQRILQLF
MMAR_1785|M.marinum_M GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MUL_2033|M.ulcerans_Agy99 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVF
MAV_3777|M.avium_104 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVDEVDARILQVF
Mb2946c|M.bovis_AF2122/97 GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
Rv2922c|M.tuberculosis_H37Rv GRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVF
MLBr_01629|M.leprae_Br4923 GRVNPLALEEFAALEERYNFLSTQLEDVKGARKDLLDVVAEVDARILQVF
MAB_3246c|M.abscessus_ATCC_199 GKVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDERILQVF
*:***************************.** ***.*: :** ****:*
Mvan_2175|M.vanbaalenii_PYR-1 TEAYMDVEREFTQVFSTLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
Mflv_4188|M.gilvum_PYR-GCK TEAYMDVEREFTQVFSTLFPGGEGRLLLTNPSDMLTTGIEVEARPPGKKI
MSMEG_2423|M.smegmatis_MC2_155 TEAYADVEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKI
TH_1649|M.thermoresistible__bu AEAYTDVEREFREVFATLFPGGEGRLLLTDPNDMLTTGVEVEARPPGKKI
MMAR_1785|M.marinum_M SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MUL_2033|M.ulcerans_Agy99 SDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKV
MAV_3777|M.avium_104 SEAYTDVEREFSDVFGVLFPGGEGRLRLTDPSNMLTTGIEVEARPPGKKI
Mb2946c|M.bovis_AF2122/97 NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
Rv2922c|M.tuberculosis_H37Rv NDAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKI
MLBr_01629|M.leprae_Br4923 SDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIEVEARPSGKKV
MAB_3246c|M.abscessus_ATCC_199 TEAYADVEREFKGVFSSLFPGGEGRLVLTDPNDMLTTGIEVEARPPGKKV
:*: ****** ** ********* ** *.:*****:******.***:
Mvan_2175|M.vanbaalenii_PYR-1 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
Mflv_4188|M.gilvum_PYR-GCK KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
MSMEG_2423|M.smegmatis_MC2_155 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
TH_1649|M.thermoresistible__bu KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLIS
MMAR_1785|M.marinum_M SRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MUL_2033|M.ulcerans_Agy99 SRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIG
MAV_3777|M.avium_104 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDTNLRRLIS
Mb2946c|M.bovis_AF2122/97 TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
Rv2922c|M.tuberculosis_H37Rv TRLSLLSGGEKALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLS
MLBr_01629|M.leprae_Br4923 SRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAALDDVNLCRLIG
MAB_3246c|M.abscessus_ATCC_199 KRLSLLSGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLQRLIG
.**********:* ***:*****:*******:**********.** **:.
Mvan_2175|M.vanbaalenii_PYR-1 LFEQLRERSQLIVITHQKPTMEVADALYGVTMRGDGITTVISQRMRGQ--
Mflv_4188|M.gilvum_PYR-GCK LFEQLRERSQLIVITHQKPTMEVADALYGVTMQGDGITTVISQRMRGQ--
MSMEG_2423|M.smegmatis_MC2_155 LFEQLREKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQ--
TH_1649|M.thermoresistible__bu LFEQLRERSQLIVITHQKPTMEVADALYGVTMRDDGITTVISQRLRGQ--
MMAR_1785|M.marinum_M LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MUL_2033|M.ulcerans_Agy99 LFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQV
MAV_3777|M.avium_104 LFELLRARSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRMRGQQV
Mb2946c|M.bovis_AF2122/97 LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
Rv2922c|M.tuberculosis_H37Rv LFEQLREQSQIIIITHQKPTMEVADALYGVTMQNDGITAVISQRMRGQQV
MLBr_01629|M.leprae_Br4923 VFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAVISQRMRGQQV
MAB_3246c|M.abscessus_ATCC_199 LFEQLREKSQLIVITHQKPTMEVADALYGVSMRDDGITQVVSQRMRGLET
:** ** :**:*:*********:**:****:*:.**** *:***:**
Mvan_2175|M.vanbaalenii_PYR-1 -ELVASPS
Mflv_4188|M.gilvum_PYR-GCK -ELVTSSS
MSMEG_2423|M.smegmatis_MC2_155 -ELVSNPS
TH_1649|M.thermoresistible__bu -ELVAQPG
MMAR_1785|M.marinum_M DRLVANSS
MUL_2033|M.ulcerans_Agy99 DRLVANSS
MAV_3777|M.avium_104 DQLVTT--
Mb2946c|M.bovis_AF2122/97 DQLVTNSS
Rv2922c|M.tuberculosis_H37Rv DQLVTNSS
MLBr_01629|M.leprae_Br4923 ESLVTSSS
MAB_3246c|M.abscessus_ATCC_199 -QLASQNA
*.: