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MKLHRLALTNYRGTARREIEFPDRGVILVCGANEIGKSSMIEALDLLLEFRDRSTKKEVKQVKPANADIG SEVCAEISSGTYRFVYRKRFNKKCETALTVLAPHREQLTGDEAHERVRAMLAETVDNDLWHAQRVLQAAS TAAVDLSGCDALSRALDLAAGDHAELSGTEPLLIERIEAEYRRYFTSTGRPTGEWAVAISRLSDAETAVG ECAAAVAEVDDRVRRHAVLTERVAGLAQQRFAAGPRLAVAQAAADKVAVLTRQAREAELVAAAATATNAA AVAAHTSRLRLLAEIDTRAVVLAATQDEAQEAVDAVSTMRADAEASDAAVEESTEALMAAQQRADIARST VDQLVDRQEADRLSTRLAKIDAIQGERDLICAELSAVTLTEQLLQRIENAAAIVDRTGEQLKLISAAVEF TATADIEISVGQQRVSLEAGQSWSTTATGPTEVEVLGVLTACVIPGATALDAQSKYVAAQEELSVALADG GVVDLAAARCANQRRRELQSSLDQLSAALAGVCGDDQIDQLRARLEQLRDGYPGEPDLLAVDIGSARAEL EAAETVRAAVDFEREVCRRTAAAANCRLVETSARANFLLKKAETQRAELDQDIDQLAQQRASVSDEDLAS AAEAGLRAVQIAEQRVAKLTEELVAAEPEAVTAELVAATAAAESLRDQHEDAAGALREISIELSVFGTEG RQGKLDTAEAEREHAISQHTQIGRRARAAQLLRSVMARHRDTTRLRYVEPYRTELQRLGRPVFGPTFEVD IDSDLRIRSRTLDGITVPFESLSGGAKEQLGILARFAGATLVAKEDNVPVVVDDALGFTDPDRLAKMGEM FDTVGAHGQVIVLTCSPDRYDGFTGAHRIDLNV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_01120 | - | - | 100% (873) | hypothetical protein MLBr_01120 |
M. leprae Br4923 | MLBr_00510 | - | 4e-06 | 24.70% (247) | recombination factor protein RarA |
M. leprae Br4923 | MLBr_01629 | smc | 3e-05 | 24.44% (270) | putative cell division protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1309 | - | 0.0 | 69.38% (872) | hypothetical protein Mb1309 |
M. gilvum PYR-GCK | Mflv_2256 | - | 0.0 | 52.50% (880) | hypothetical protein Mflv_2256 |
M. tuberculosis H37Rv | Rv1278 | - | 0.0 | 69.38% (872) | hypothetical protein Rv1278 |
M. abscessus ATCC 19977 | MAB_1421 | - | 0.0 | 49.03% (873) | hypothetical protein MAB_1421 |
M. marinum M | MMAR_4142 | - | 0.0 | 69.29% (876) | hydrolase |
M. avium 104 | MAV_1428 | - | 0.0 | 68.80% (875) | hypothetical protein MAV_1428 |
M. smegmatis MC2 155 | MSMEG_5002 | - | 0.0 | 53.71% (875) | hypothetical protein MSMEG_5002 |
M. thermoresistible (build 8) | TH_1853 | - | 0.0 | 55.11% (871) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_4005 | - | 0.0 | 69.18% (876) | hydrolase |
M. vanbaalenii PYR-1 | Mvan_4435 | - | 0.0 | 51.93% (882) | hypothetical protein Mvan_4435 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2256|M.gilvum_PYR-GCK MKLHRLVLTNYRGITHRDIEFPDRGVVVVSGANEVGKSSMLEALDLLLES Mvan_4435|M.vanbaalenii_PYR-1 MKLHRLALTNYRGITHRDIEFPDRGVVVVSGPNEAGKSSMLEALDLLLES MSMEG_5002|M.smegmatis_MC2_155 MKLHRLVLTNYRGITHREIEFPDHGVVVVSGANEIGKSSMIEALDLLIEA TH_1853|M.thermoresistible__bu MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHA Mb1309|M.bovis_AF2122/97 MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY Rv1278|M.tuberculosis_H37Rv MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY MMAR_4142|M.marinum_M MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF MUL_4005|M.ulcerans_Agy99 MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF MLBr_01120|M.leprae_Br4923 MKLHRLALTNYRGTARREIEFPDRGVILVCGANEIGKSSMIEALDLLLEF MAV_1428|M.avium_104 MKLHRLTLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEA MAB_1421|M.abscessus_ATCC_1997 MKLHRLSVTNYRGITHRDITFPERGVVVVGGANEVGKTSMIEALDLLIES *:**** :***** ::*:: **::**::* *.** **:**:******:. Mflv_2256|M.gilvum_PYR-GCK KDRSNKKEIKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKKPETELTV Mvan_4435|M.vanbaalenii_PYR-1 KDRSSKKEVKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKRPETELTV MSMEG_5002|M.smegmatis_MC2_155 KDRSSKKEVKQVKPTHADVGAEVSAEISTGPYRFLYRKRFHKRAETQLTI TH_1853|M.thermoresistible__bu KDRSTKKEVKQVKPTHADVGAEITAEISTGPYRFVYHKRFHKKCATQLTI Mb1309|M.bovis_AF2122/97 KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV Rv1278|M.tuberculosis_H37Rv KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV MMAR_4142|M.marinum_M KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV MUL_4005|M.ulcerans_Agy99 KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV MLBr_01120|M.leprae_Br4923 RDRSTKKEVKQVKPANADIGSEVCAEISSGTYRFVYRKRFNKKCETALTV MAV_1428|M.avium_104 KDRSTKKEVKQVKPTHSDVGAEVSAEISCGPYRFVYRKRFHKKCETELTV MAB_1421|M.abscessus_ATCC_1997 KDRSTKKDVKQVKPTFADVGSEVEAEISCGPYRFVYRKRFHKRAETHLTV :*** **::*****: :*:*:*: **** *.***:*:***:*: * **: Mflv_2256|M.gilvum_PYR-GCK VAPRRQQFTGDEAHERVRAMLAETVDLDLWQAQRVLQSAPTTAADLSACD Mvan_4435|M.vanbaalenii_PYR-1 LTPRREQLTGDEAHERVRAILAESVDLDLWQAQRVLQSAPTSAADLSGCN MSMEG_5002|M.smegmatis_MC2_155 LSPVREQLSGDEAHQRVLAMLAETVDTDLWQAQRVLQASSTAPVDLSGSD TH_1853|M.thermoresistible__bu LAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQAGSTAPVDLSGCD Mb1309|M.bovis_AF2122/97 LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD Rv1278|M.tuberculosis_H37Rv LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD MMAR_4142|M.marinum_M LAPRREQLTGDEAHERVRAILAETVDTELWRAQRVLQAASTTAVDLSSCD MUL_4005|M.ulcerans_Agy99 LAPRREQLTGDEAHERVRAILAETVDTKLWRAQRVLQAASTTAVDLSSCD MLBr_01120|M.leprae_Br4923 LAPHREQLTGDEAHERVRAMLAETVDNDLWHAQRVLQAASTAAVDLSGCD MAV_1428|M.avium_104 ITPYREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQAASTAAVDLSGCD MAB_1421|M.abscessus_ATCC_1997 IEPRREQLSGDEAHQRVLDMLDQSIDMNLWKAQRVLQSAGAGVLDLSSSD : * *::::*****:*. :* :::* .**::*****:. : ***..: Mflv_2256|M.gilvum_PYR-GCK ALSRALDVVAGEVD-DDPAPG-GAVDTLLVDRIDEEYRRYFTLTGKPTGE Mvan_4435|M.vanbaalenii_PYR-1 ALSRALDVVAGEVD-DVSATGAGNVESLLVDRVEEEYRRYFTSTGRATGE MSMEG_5002|M.smegmatis_MC2_155 ALARALDVAAGEA---VSLSG---DEPLLIERIEGEYQRYFTATGRPTGE TH_1853|M.thermoresistible__bu ALSRALDAVAGEA---VQTSG---TEPLLIDRIDAEYRKYFTATGRPTGE Mb1309|M.bovis_AF2122/97 ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE Rv1278|M.tuberculosis_H37Rv ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE MMAR_4142|M.marinum_M ALSRALDIAAAHSATDVALSG---AEPVLIERIDTEYSRYFTPTGRPTGE MUL_4005|M.ulcerans_Agy99 ALSRALDIAAAHSATDVALSG---AEPVLIERIDAEYSRYFTPTGRPTGE MLBr_01120|M.leprae_Br4923 ALSRALDLAAGDHA---ELSG---TEPLLIERIEAEYRRYFTSTGRPTGE MAV_1428|M.avium_104 ALSRALDVAAGDSG---GLCG---TEPLLIERIDAEYARYFTPTGRPTGE MAB_1421|M.abscessus_ATCC_1997 ALTRALDLAAGQS---VALSG---SEPDLVERIDAEYALYFTGTGRPTGE **:**** .*.. * :. *::*:: ** *** **:.*** Mflv_2256|M.gilvum_PYR-GCK WAAATKRLRDADEQVARCAAAVAEVDEAVRRHAALTADLAVLSAERVTAA Mvan_4435|M.vanbaalenii_PYR-1 WAAATARLRAADEEVARCAAAMAEVDEAVRRHAALTTDMAQLAVETASAA MSMEG_5002|M.smegmatis_MC2_155 WAAAVKRLQAADAEVARCAAAVAEVDDAVHRHQELSAEVSRLAGECEQAT TH_1853|M.thermoresistible__bu WLAATKRLQAADEQVARCAARVAEVEDAVRRHATLTESLAELEDGRRTAD Mb1309|M.bovis_AF2122/97 WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ Rv1278|M.tuberculosis_H37Rv WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ MMAR_4142|M.marinum_M WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPQLAAAG MUL_4005|M.ulcerans_Agy99 WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPKLAAAG MLBr_01120|M.leprae_Br4923 WAVAISRLSDAETAVGECAAAVAEVDDRVRRHAVLTERVAGLAQQRFAAG MAV_1428|M.avium_104 WAAAIARLADAEAAVAECAAAVAEVDERVSRHAALTEQVADLSQRRIAAG MAB_1421|M.abscessus_ATCC_1997 WARAGARLTAAEDALASARAAMAEVDQQVREHDELTQELASVIADRAEVN * : ** *: :. . * ::**:: : .* *: : : Mflv_2256|M.gilvum_PYR-GCK AHLESAAQAEKKVAALRADLDRATARAEAATSTHTASQSALTERRRCRAD Mvan_4435|M.vanbaalenii_PYR-1 ERLQSARNAAAAVAVLQGELDQATARAEAARSVHAASKAALAQRRRARAD MSMEG_5002|M.smegmatis_MC2_155 QRLTATRTAADAVDALRQQLKEAQVVAEAAHVTHAASVAALTERRRMRAE TH_1853|M.thermoresistible__bu AQLAAAREAAEAVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAE Mb1309|M.bovis_AF2122/97 LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE Rv1278|M.tuberculosis_H37Rv LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE MMAR_4142|M.marinum_M SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE MUL_4005|M.ulcerans_Agy99 SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE MLBr_01120|M.leprae_Br4923 PRLAVAQAAADKVAVLTRQAREAELVAAAATATNAAAVAAHTSRLRLLAE MAV_1428|M.avium_104 PRVTAARQAADRIAELTAQRREAQLVAEAAAATKAAAAQAHSGRLQLLAD MAB_1421|M.abscessus_ATCC_1997 RRLAPLEEASQAVTTLVQQHDNAVVVAEAAQAAAVAAQTKRDERAQLVAD :: * : : : .* : * . *: * : Mflv_2256|M.gilvum_PYR-GCK IDDRTATITRLQAESAVATDELDTAAQMKVAADEAAEKARLALTAGQERV Mvan_4435|M.vanbaalenii_PYR-1 LDERSATVTSLQTESDTAADELDTANEMQVAAEEAAGKARSALAACQERV MSMEG_5002|M.smegmatis_MC2_155 IDERAATITELQAALVTAAEEAETAREVVTAAEEEAERAKAAVADHEARV TH_1853|M.thermoresistible__bu IEERTAAVAALQPEVDAALEAEATAREVQQEADTAAERAREAADAARERV Mb1309|M.bovis_AF2122/97 IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA Rv1278|M.tuberculosis_H37Rv IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA MMAR_4142|M.marinum_M IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA MUL_4005|M.ulcerans_Agy99 IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA MLBr_01120|M.leprae_Br4923 IDTRAVVLAATQDEAQEAVDAVSTMRADAEASDAAVEESTEALMAAQQRA MAV_1428|M.avium_104 IDTRAAAVTQTHAQVQQAAADHAVAQADAQACDTALQHATEALAELERRV MAB_1421|M.abscessus_ATCC_1997 IRARRVSIDMLAEQLSATAEAHGTAQQVCEAAEAAAAQATESVDAARVQL : * : : .: .: . : Mflv_2256|M.gilvum_PYR-GCK DAARGAVQRLADREEVDRLAGRIATIERHQRELDAVSGELAAIALTDPLM Mvan_4435|M.vanbaalenii_PYR-1 DAARVAVQRLADREEADRLTGRIATIERHGRELEAVQRDLTAITLTDALL MSMEG_5002|M.smegmatis_MC2_155 DAARAAVERLSDRDEADRLDMRLAKIDAATRELQAVTDELKTITLDDTAM TH_1853|M.thermoresistible__bu DTARQAVQRLADRAERDTLADRLRRIDAAATELARVDGELATLTVTEAAL Mb1309|M.bovis_AF2122/97 ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL Rv1278|M.tuberculosis_H37Rv ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL MMAR_4142|M.marinum_M EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL MUL_4005|M.ulcerans_Agy99 EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL MLBr_01120|M.leprae_Br4923 DIARSTVDQLVDRQEADRLSTRLAKIDAIQGERDLICAELSAVTLTEQLL MAV_1428|M.avium_104 QEAQRTVERSAGREEADRLAARLDKIDAIQRDRERISAELSTIAVTEELL MAB_1421|M.abscessus_ATCC_1997 EAARGTLDRALARDEVDGLAARVSRIDLTNRQLASVGAELSSLVITAQSL : *: :::: : : * *: * : : :* :.: : Mflv_2256|M.gilvum_PYR-GCK TAIEKAAAVVDRATAAVAYASARMELVAAADLEISVDGSTVTLNAGDTWS Mvan_4435|M.vanbaalenii_PYR-1 ADIETAAAAVERATAAVEQTSAHIEVTAAADVEVRIGDADMTLRAGDTWA MSMEG_5002|M.smegmatis_MC2_155 RAIEKAALAVERAAGQAELASARIELVAQNGLDVRVDDATVALQAGAEWS TH_1853|M.thermoresistible__bu RQIEAAELAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWT Mb1309|M.bovis_AF2122/97 SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS Rv1278|M.tuberculosis_H37Rv SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS MMAR_4142|M.marinum_M KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVGGQRVQLSAGSSWS MUL_4005|M.ulcerans_Agy99 KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVDGQRVQLSAGLSWS MLBr_01120|M.leprae_Br4923 QRIENAAAIVDRTGEQLKLISAAVEFTATADIEISVGQQRVSLEAGQSWS MAV_1428|M.avium_104 RRIEDAAAAVDRIGDQLASTSAAVEFTAVADIHLVIGDRQVSLPAGQSWS MAB_1421|M.abscessus_ATCC_1997 GAIETAARAVGMAEAALETASAQVELRALVDVDIAVNGEQLRVAAGDRWS ** * * ** :*. * .:.: :. : : ** *: Mflv_2256|M.gilvum_PYR-GCK AGVSADTGVDVAGVLSLRITPGASASATQSELDDATAALSDALAQAGVAD Mvan_4435|M.vanbaalenii_PYR-1 AAVGTATGIDLPGVLSVQVIPGASAAATAAALDTAAARLADALRAAGVDD MSMEG_5002|M.smegmatis_MC2_155 VSTTTRTEIDVPGVLSVRVVPGTPAAETQARLDDAQAVLTAALQAVGAES TH_1853|M.thermoresistible__bu AGATAPTEIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVAD Mb1309|M.bovis_AF2122/97 VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD Rv1278|M.tuberculosis_H37Rv VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD MMAR_4142|M.marinum_M MTATGPAEVEVPGVLTARITQGATALEAQAKYVAAQEELAVALAAGGVAT MUL_4005|M.ulcerans_Agy99 MTATGPAEVEVPGVLTARIIQGATALEAQAKYVAAQEELAVALAAGGVAT MLBr_01120|M.leprae_Br4923 TTATGPTEVEVLGVLTACVIPGATALDAQSKYVAAQEELSVALADGGVVD MAV_1428|M.avium_104 ITAVGPTAVEVPGVLTARVTPGATTLDVQAKHAAAQQELAAALTAGAVAD MAB_1421|M.abscessus_ATCC_1997 SAATDTIEITAPGVAVARIIPGPNAAQLRDKLDTARQTLSGALADAGVAD . : *: : *. : * *: ** . Mflv_2256|M.gilvum_PYR-GCK LAAARALDAHRQQLCGARRQVSAILDALTAEDSVADLQTRLTAVQARIP- Mvan_4435|M.vanbaalenii_PYR-1 VEAARALDRRRHELSAAGRQIRAILEALAADDSVDQLRARLADLQARTP- MSMEG_5002|M.smegmatis_MC2_155 VDVARALDARRRELLGSRDRLRATLDALVGDDDIARLRDRLAALRAGQT- TH_1853|M.thermoresistible__bu VASARSQVERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAAS- Mb1309|M.bovis_AF2122/97 LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP- Rv1278|M.tuberculosis_H37Rv LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP- MMAR_4142|M.marinum_M LAEARSVEQRRRELLGRRDQLSATLAGLCGDEQVDQLRCRLAQLQASQP- MUL_4005|M.ulcerans_Agy99 LAEARSVEQRRRELLGRRDQLNATLAGLCGDEQVDQLRCRLAQLQASQP- MLBr_01120|M.leprae_Br4923 LAAARCANQRRRELQSSLDQLSAALAGVCGDDQIDQLRARLEQLRDGYP- MAV_1428|M.avium_104 LGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDELRSRLARLRAEHPE MAB_1421|M.abscessus_ATCC_1997 VGEAQKQFERRTELNAERDRLTALLDGLMGPESLEALREKLSRLRELVP- : *: * :* . * : .: . : : *: :* : . Mflv_2256|M.gilvum_PYR-GCK --AADGLFDTDA-AILDPAAQRLELIEATAAHQDAIRDCETHRKVADQAG Mvan_4435|M.vanbaalenii_PYR-1 --AEEGLFDTDTRGSLDPAAQRLELVEATAAHQQAIRDCETHRKVAEEAA MSMEG_5002|M.smegmatis_MC2_155 --DDGGLFDVEGPADID--TARAQLAADVAAHREAVAHCETARKAVAVAA TH_1853|M.thermoresistible__bu --DDTGELGVDD--------AQAELTAAERAYQQAHTDCETHRKAAVLAA Mb1309|M.bovis_AF2122/97 --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA Rv1278|M.tuberculosis_H37Rv --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA MMAR_4142|M.marinum_M --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLALAAS MUL_4005|M.ulcerans_Agy99 --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLAVAAS MLBr_01120|M.leprae_Br4923 --GEPDLLAVDI------GSARAELEAAETVRAAVDFEREVCRRTAAAAN MAV_1428|M.avium_104 QPAAPTGGAADL------AAARTELEALAQARACASAECVTRRQAATAAA MAB_1421|M.abscessus_ATCC_1997 --EATGLWDAIDP-----AQARAEVARLVGEVERLQAEEVTHRRAVQTAG . : :: . *: . * Mflv_2256|M.gilvum_PYR-GCK KLVAQRELNAARIAQKLQSAQHELTTIAARLAEQRASVGDEELALKTDAD Mvan_4435|M.vanbaalenii_PYR-1 KLSAKRGLHAARLLEKLQAAQAELAAAGARLAEQRAATSDDELAVKAEAD MSMEG_5002|M.smegmatis_MC2_155 ARDTEKSTRLSVLREKLTAAQTELTTCSARLEAQRAGTPDEALALKVQAD TH_1853|M.thermoresistible__bu RRLAEKSQTAAALREKLTAARTELDTAAARLAAQRADVDDETLVVRAAAH Mb1309|M.bovis_AF2122/97 RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD Rv1278|M.tuberculosis_H37Rv RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD MMAR_4142|M.marinum_M RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD MUL_4005|M.ulcerans_Agy99 RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD MLBr_01120|M.leprae_Br4923 CRLVETSARANFLLKKAETQRAELDQDIDQLAQQRASVSDEDLASAAEAG MAV_1428|M.avium_104 ARLAETATAATVLQNRLDTLRAELDAATGRLAAERASVGDEELAASADAA MAB_1421|M.abscessus_ATCC_1997 QQLAEKAAEAMAAREKHAARAEELAAAEQRLAHVRSSASDDLLTERHERA .: . *: :* *: . * *. Mflv_2256|M.gilvum_PYR-GCK AETAAKAVAAVAELRDELARHHPDAVVAALAEAERALATVTARRDEAVEA Mvan_4435|M.vanbaalenii_PYR-1 AEAAAAAEAAVARVGAELAGHEPEAVAAALVDAERAAAEVGARHHEVGEA MSMEG_5002|M.smegmatis_MC2_155 DEQAKATAARVATLRDELDRSAPDSVLAELADAQRHAQSVQTRHDAATEG TH_1853|M.thermoresistible__bu GEEAERAAVRVAQLNAELSAAQPDQVAAALDTAARHAETVHAEHRRTADA Mb1309|M.bovis_AF2122/97 LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA Rv1278|M.tuberculosis_H37Rv LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA MMAR_4142|M.marinum_M LHVLQASQRRLAELAEVLDAAEPEAVAAELREAAEIAQSLDERHDAVVAA MUL_4005|M.ulcerans_Agy99 LHVLQASQRRLAELTEVLDAAEPEAVAAEAREAAEIAQSLGERHDAVVAA MLBr_01120|M.leprae_Br4923 LRAVQIAEQRVAKLTEELVAAEPEAVTAELVAATAAAESLRDQHEDAAGA MAV_1428|M.avium_104 LRAEQAAERRVAELADALAAASPDSVAAELADATQESESLRERYEEAAGA MAB_1421|M.abscessus_ATCC_1997 VQAADLTSRRVTDLVSQLAALEADRVRAELAEVSARAQALDRRHEATRDR . : : : * .: * * . : . . Mflv_2256|M.gilvum_PYR-GCK LREIAAQLKVFGTEGRKGNLDAAETERERAEAEFGRVQRRARAAQLLRTV Mvan_4435|M.vanbaalenii_PYR-1 LREIAAQLKVYGTEGRKGGLDAAETERGRAEAEFVRVQRRARAAELLRSV MSMEG_5002|M.smegmatis_MC2_155 LREVSAQLKVYGTEGRKGQLDEAETEREHANAEYLRVHRRARAAELLRSV TH_1853|M.thermoresistible__bu LRELNAQLEVYGSEGRKGELDAAKAEREQAEAEFLRIGRLARAVKLLRET Mb1309|M.bovis_AF2122/97 LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV Rv1278|M.tuberculosis_H37Rv LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV MMAR_4142|M.marinum_M LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV MUL_4005|M.ulcerans_Agy99 LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV MLBr_01120|M.leprae_Br4923 LREISIELSVFGTEGRQGKLDTAEAEREHAISQHTQIGRRARAAQLLRSV MAV_1428|M.avium_104 LREVTIELSVFGSEGRQGKLDAAETEREHAASEHSQVGRRARAAQLLRSV MAB_1421|M.abscessus_ATCC_1997 LRDISVRLEVFGRQGRQDQLDAAASEREYAATEFARIGAKARAVDTLRSV *::: .*.*:* :**:. ** * :** * :.. :: ***. ** . Mflv_2256|M.gilvum_PYR-GCK MGRHRDAMRQRYVDPFRTEVERLGRIVFGDTFEVDVDSELRIGHRTLSGR Mvan_4435|M.vanbaalenii_PYR-1 MGRHRDAMRQRYVDPFRGEVERLGRIVFGDSFEVDVDSSLCIGNRTLSGR MSMEG_5002|M.smegmatis_MC2_155 MTRHRDATRQRYVDPFRNEVQRLGRLVFGEDFEVDVDSKLRISTRTVSGR TH_1853|M.thermoresistible__bu MLRHRDASRRRYVDPFRAEVERLGRIVFGDSFEVEIDSDLCIRSRTLAGR Mb1309|M.bovis_AF2122/97 MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR Rv1278|M.tuberculosis_H37Rv MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR MMAR_4142|M.marinum_M MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV MUL_4005|M.ulcerans_Agy99 MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV MLBr_01120|M.leprae_Br4923 MARHRDTTRLRYVEPYRTELQRLGRPVFGPTFEVDIDSDLRIRSRTLDGI MAV_1428|M.avium_104 MTRHRDTTRQRYVEPYRAELQRLGRPVFGPTFEVDIDSDLCIRSRTLNGI MAB_1421|M.abscessus_ATCC_1997 MMRHRDGMRLRYVDPFRAELERLGRMVFGPTFEVDIDSDLSIRSRTLEGR * **** * ***:*:* *:.**** *** ***::.:.* * **: . Mflv_2256|M.gilvum_PYR-GCK TVPYESLSGGAKEQLGIVARLAGATLVASEDSVPVVIDDALGFTDADRLT Mvan_4435|M.vanbaalenii_PYR-1 TVPYESLSGGAKEQLGIVARLAGAALVAKEDSVPVVIDDALGFTDTERLT MSMEG_5002|M.smegmatis_MC2_155 TVPYESLSGGAKEQLAIVARLAGASLVAKEDTVPVIIDDALGFTDADRLT TH_1853|M.thermoresistible__bu TVDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFTDAERLV Mb1309|M.bovis_AF2122/97 TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA Rv1278|M.tuberculosis_H37Rv TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA MMAR_4142|M.marinum_M TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA MUL_4005|M.ulcerans_Agy99 TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA MLBr_01120|M.leprae_Br4923 TVPFESLSGGAKEQLGILARFAGATLVAKEDNVPVVVDDALGFTDPDRLA MAV_1428|M.avium_104 TVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLA MAB_1421|M.abscessus_ATCC_1997 TVPYESLSGGAKEQLGIVARLASAALVAPQDAVPVIIDDALGFTDSDRLE ** :*.*********.*:**:*.*:*** :* ***::********.:** Mflv_2256|M.gilvum_PYR-GCK KMAEVFDAVAGDGQVIILTCSPQRYADVRSARHIELVAG- Mvan_4435|M.vanbaalenii_PYR-1 KMAEVFDAVAGDGQVIILTCSPQRYAGVRTAQHIELIAG- MSMEG_5002|M.smegmatis_MC2_155 KMGAVFDAVGGDGQVIVLTCSPDRYASVHGAHHIALTA-- TH_1853|M.thermoresistible__bu KMGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA-- Mb1309|M.bovis_AF2122/97 KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ Rv1278|M.tuberculosis_H37Rv KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ MMAR_4142|M.marinum_M KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL-- MUL_4005|M.ulcerans_Agy99 KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL-- MLBr_01120|M.leprae_Br4923 KMGEMFDTVGAHGQVIVLTCSPDRYDGFTGAHRIDLNV-- MAV_1428|M.avium_104 KMGQLFDSVGSHGQVIVLTCSPDRYDGVKGAHRIDLSA-- MAB_1421|M.abscessus_ATCC_1997 RMGEVFGAVGTETQVIVLTCSPDRYRAVTGAQRISLSA-- :*. :*.::. . ***:***** ** . *::* *