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KLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEFKDRSAKKEIKQVKPTNADVGS EVTAEISSGPYRFVYRKRFHKKCETQLTVLAPRREQLTGDEAHERVRAILAETVDTKLWRAQRVLQAAST TAVDLSSCDALSRALDIAAAHSATDVALSGAEPVLIERIDAEYSRYFTPTGRPTGEWAATLARLSGAETA VAECAAAVSEVDERISRHGELTRQAAELAPKLAAAGSRLAAARQAADKVAGLKAEAHEAKLVTAAKAATS SASAAAHAERRALCEEIDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRAEAAR RSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALLKRIESAAASVDRVDGQLALISAAV EFTAAADIELVVDGQRVQLSAGLSWSMTATGPAEVEVPGVLTARIIQGATALEAQAKYVAAQEELAVALA AGGVATLAEARSVEQRRRELLGRRDQLNATLAGLCGDEQVDQLRCRLAQLQASQPAEPDLFATDATAARA ELEAAEAARITAGKQCEDQRKLAVAASRRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADL ASAADADLHVLQASQRRLAELTEVLDAAEPEAVAAEAREAAEIAQSLGERHDAVVAALRDISVELSVFGS EGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSVMTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFE VDVGSDLRIRSRTLDDVTVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLAKMG GVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4005 | - | - | 100% (876) | hydrolase |
| M. ulcerans Agy99 | MUL_2033 | smc | 2e-11 | 25.07% (714) | chromosome partition protein Smc |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1309 | - | 0.0 | 71.43% (875) | hypothetical protein Mb1309 |
| M. gilvum PYR-GCK | Mflv_2256 | - | 0.0 | 53.75% (880) | hypothetical protein Mflv_2256 |
| M. tuberculosis H37Rv | Rv1278 | - | 0.0 | 71.43% (875) | hypothetical protein Rv1278 |
| M. leprae Br4923 | MLBr_01120 | - | 0.0 | 69.18% (876) | hypothetical protein MLBr_01120 |
| M. abscessus ATCC 19977 | MAB_1421 | - | 0.0 | 49.77% (878) | hypothetical protein MAB_1421 |
| M. marinum M | MMAR_4142 | - | 0.0 | 98.74% (876) | hydrolase |
| M. avium 104 | MAV_1428 | - | 0.0 | 68.56% (878) | hypothetical protein MAV_1428 |
| M. smegmatis MC2 155 | MSMEG_5002 | - | 0.0 | 54.67% (878) | hypothetical protein MSMEG_5002 |
| M. thermoresistible (build 8) | TH_1853 | - | 0.0 | 54.58% (874) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_4435 | - | 0.0 | 53.45% (883) | hypothetical protein Mvan_4435 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2256|M.gilvum_PYR-GCK MKLHRLVLTNYRGITHRDIEFPDRGVVVVSGANEVGKSSMLEALDLLLES
Mvan_4435|M.vanbaalenii_PYR-1 MKLHRLALTNYRGITHRDIEFPDRGVVVVSGPNEAGKSSMLEALDLLLES
MSMEG_5002|M.smegmatis_MC2_155 MKLHRLVLTNYRGITHREIEFPDHGVVVVSGANEIGKSSMIEALDLLIEA
TH_1853|M.thermoresistible__bu MRLHRLALTNYRGIARREVEFPDRGVVVVSGANEIGKSSMIEALDLLFHA
Mb1309|M.bovis_AF2122/97 MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
Rv1278|M.tuberculosis_H37Rv MKLHRLALTNYRGIAHRDVEFPDHGVVVVCGANEIGKSSMVEALDLLLEY
MUL_4005|M.ulcerans_Agy99 MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MMAR_4142|M.marinum_M MKLHRLVLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEF
MLBr_01120|M.leprae_Br4923 MKLHRLALTNYRGTARREIEFPDRGVILVCGANEIGKSSMIEALDLLLEF
MAV_1428|M.avium_104 MKLHRLTLTNYRGIAHREIEFPDHGVVVVCGANEIGKSSMIEALDLLLEA
MAB_1421|M.abscessus_ATCC_1997 MKLHRLSVTNYRGITHRDITFPERGVVVVGGANEVGKTSMIEALDLLIES
*:**** :***** ::*:: **::**::* *.** **:**:******:.
Mflv_2256|M.gilvum_PYR-GCK KDRSNKKEIKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKKPETELTV
Mvan_4435|M.vanbaalenii_PYR-1 KDRSSKKEVKQVKPTHADVGAEVTAEISAGPYRFVYRKRFHKRPETELTV
MSMEG_5002|M.smegmatis_MC2_155 KDRSSKKEVKQVKPTHADVGAEVSAEISTGPYRFLYRKRFHKRAETQLTI
TH_1853|M.thermoresistible__bu KDRSTKKEVKQVKPTHADVGAEITAEISTGPYRFVYHKRFHKKCATQLTI
Mb1309|M.bovis_AF2122/97 KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
Rv1278|M.tuberculosis_H37Rv KDRSTKKEVKQVKPTNADVGSEVIAEISSGPYRFVYRKRFHKRCETELTV
MUL_4005|M.ulcerans_Agy99 KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MMAR_4142|M.marinum_M KDRSAKKEIKQVKPTNADVGSEVTAEISSGPYRFVYRKRFHKKCETQLTV
MLBr_01120|M.leprae_Br4923 RDRSTKKEVKQVKPANADIGSEVCAEISSGTYRFVYRKRFNKKCETALTV
MAV_1428|M.avium_104 KDRSTKKEVKQVKPTHSDVGAEVSAEISCGPYRFVYRKRFHKKCETELTV
MAB_1421|M.abscessus_ATCC_1997 KDRSTKKDVKQVKPTFADVGSEVEAEISCGPYRFVYRKRFHKRAETHLTV
:*** **::*****: :*:*:*: **** *.***:*:***:*: * **:
Mflv_2256|M.gilvum_PYR-GCK VAPRRQQFTGDEAHERVRAMLAETVDLDLWQAQRVLQSAPTTAADLSACD
Mvan_4435|M.vanbaalenii_PYR-1 LTPRREQLTGDEAHERVRAILAESVDLDLWQAQRVLQSAPTSAADLSGCN
MSMEG_5002|M.smegmatis_MC2_155 LSPVREQLSGDEAHQRVLAMLAETVDTDLWQAQRVLQASSTAPVDLSGSD
TH_1853|M.thermoresistible__bu LAPRREELSGDEAHERALAMLSETVDMELWRTQRVLQAGSTAPVDLSGCD
Mb1309|M.bovis_AF2122/97 LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
Rv1278|M.tuberculosis_H37Rv LAPRREQLTGDEAHERVRTMLAETVDTELWHAQRVLQAASTAAVDLSGCD
MUL_4005|M.ulcerans_Agy99 LAPRREQLTGDEAHERVRAILAETVDTKLWRAQRVLQAASTTAVDLSSCD
MMAR_4142|M.marinum_M LAPRREQLTGDEAHERVRAILAETVDTELWRAQRVLQAASTTAVDLSSCD
MLBr_01120|M.leprae_Br4923 LAPHREQLTGDEAHERVRAMLAETVDNDLWHAQRVLQAASTAAVDLSGCD
MAV_1428|M.avium_104 ITPYREQLTGDEAHERVRAMLAETVDSDLWHAQRVLQAASTAAVDLSGCD
MAB_1421|M.abscessus_ATCC_1997 IEPRREQLSGDEAHQRVLDMLDQSIDMNLWKAQRVLQSAGAGVLDLSSSD
: * *::::*****:*. :* :::* .**::*****:. : ***..:
Mflv_2256|M.gilvum_PYR-GCK ALSRALDVVAGEVD-DDPAPG-GAVDTLLVDRIDEEYRRYFTLTGKPTGE
Mvan_4435|M.vanbaalenii_PYR-1 ALSRALDVVAGEVD-DVSATGAGNVESLLVDRVEEEYRRYFTSTGRATGE
MSMEG_5002|M.smegmatis_MC2_155 ALARALDVAAGEA---VSLSG---DEPLLIERIEGEYQRYFTATGRPTGE
TH_1853|M.thermoresistible__bu ALSRALDAVAGEA---VQTSG---TEPLLIDRIDAEYRKYFTATGRPTGE
Mb1309|M.bovis_AF2122/97 ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
Rv1278|M.tuberculosis_H37Rv ALSRALDLAAGDDA---ALSG---TESLLIERIEAEYARYFTPTGRPTGE
MUL_4005|M.ulcerans_Agy99 ALSRALDIAAAHSATDVALSG---AEPVLIERIDAEYSRYFTPTGRPTGE
MMAR_4142|M.marinum_M ALSRALDIAAAHSATDVALSG---AEPVLIERIDTEYSRYFTPTGRPTGE
MLBr_01120|M.leprae_Br4923 ALSRALDLAAGDHA---ELSG---TEPLLIERIEAEYRRYFTSTGRPTGE
MAV_1428|M.avium_104 ALSRALDVAAGDSG---GLCG---TEPLLIERIDAEYARYFTPTGRPTGE
MAB_1421|M.abscessus_ATCC_1997 ALTRALDLAAGQS---VALSG---SEPDLVERIDAEYALYFTGTGRPTGE
**:**** .*.. * :. *::*:: ** *** **:.***
Mflv_2256|M.gilvum_PYR-GCK WAAATKRLRDADEQVARCAAAVAEVDEAVRRHAALTADLAVLSAERVTAA
Mvan_4435|M.vanbaalenii_PYR-1 WAAATARLRAADEEVARCAAAMAEVDEAVRRHAALTTDMAQLAVETASAA
MSMEG_5002|M.smegmatis_MC2_155 WAAAVKRLQAADAEVARCAAAVAEVDDAVHRHQELSAEVSRLAGECEQAT
TH_1853|M.thermoresistible__bu WLAATKRLQAADEQVARCAARVAEVEDAVRRHATLTESLAELEDGRRTAD
Mb1309|M.bovis_AF2122/97 WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
Rv1278|M.tuberculosis_H37Rv WSAAVSRLAAAEAAVADCAAAVAEVDDGVRRHTELTEQVAELSQQLLAHQ
MUL_4005|M.ulcerans_Agy99 WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPKLAAAG
MMAR_4142|M.marinum_M WAATLARLSGAETAVAECAAAVSEVDERISRHGELTRQAAELAPQLAAAG
MLBr_01120|M.leprae_Br4923 WAVAISRLSDAETAVGECAAAVAEVDDRVRRHAVLTERVAGLAQQRFAAG
MAV_1428|M.avium_104 WAAAIARLADAEAAVAECAAAVAEVDERVSRHAALTEQVADLSQRRIAAG
MAB_1421|M.abscessus_ATCC_1997 WARAGARLTAAEDALASARAAMAEVDQQVREHDELTQELASVIADRAEVN
* : ** *: :. . * ::**:: : .* *: : :
Mflv_2256|M.gilvum_PYR-GCK AHLESAAQAEKKVAALRADLDRATARAEAATSTHTASQSALTERRRCRAD
Mvan_4435|M.vanbaalenii_PYR-1 ERLQSARNAAAAVAVLQGELDQATARAEAARSVHAASKAALAQRRRARAD
MSMEG_5002|M.smegmatis_MC2_155 QRLTATRTAADAVDALRQQLKEAQVVAEAAHVTHAASVAALTERRRMRAE
TH_1853|M.thermoresistible__bu AQLAAAREAAEAVERLTRQLAEAQLAAEAAEATHTASVAALNERRRLRAE
Mb1309|M.bovis_AF2122/97 LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
Rv1278|M.tuberculosis_H37Rv LRLEAARVAAEKIAAITDDAREAKLIATAAAATSGASTAAHAGRLGLLTE
MUL_4005|M.ulcerans_Agy99 SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MMAR_4142|M.marinum_M SRLAAARQAADKVAGLKAEAHEAKLVTAAKAATSSASAAAHAERRALCEE
MLBr_01120|M.leprae_Br4923 PRLAVAQAAADKVAVLTRQAREAELVAAAATATNAAAVAAHTSRLRLLAE
MAV_1428|M.avium_104 PRVTAARQAADRIAELTAQRREAQLVAEAAAATKAAAAQAHSGRLQLLAD
MAB_1421|M.abscessus_ATCC_1997 RRLAPLEEASQAVTTLVQQHDNAVVVAEAAQAAAVAAQTKRDERAQLVAD
:: * : : : .* : * . *: * :
Mflv_2256|M.gilvum_PYR-GCK IDDRTATITRLQAESAVATDELDTAAQMKVAADEAAEKARLALTAGQERV
Mvan_4435|M.vanbaalenii_PYR-1 LDERSATVTSLQTESDTAADELDTANEMQVAAEEAAGKARSALAACQERV
MSMEG_5002|M.smegmatis_MC2_155 IDERAATITELQAALVTAAEEAETAREVVTAAEEEAERAKAAVADHEARV
TH_1853|M.thermoresistible__bu IEERTAAVAALQPEVDAALEAEATAREVQQEADTAAERAREAADAARERV
Mb1309|M.bovis_AF2122/97 IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
Rv1278|M.tuberculosis_H37Rv IDTRTAAVVAAEAKARQAADEQATARAEAEACDAALTEATQVLTAVRLRA
MUL_4005|M.ulcerans_Agy99 IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MMAR_4142|M.marinum_M IDSRAKALEALQIDAQHAADQRAMASADAQRCDVAVEEATASLTAVQRRA
MLBr_01120|M.leprae_Br4923 IDTRAVVLAATQDEAQEAVDAVSTMRADAEASDAAVEESTEALMAAQQRA
MAV_1428|M.avium_104 IDTRAAAVTQTHAQVQQAAADHAVAQADAQACDTALQHATEALAELERRV
MAB_1421|M.abscessus_ATCC_1997 IRARRVSIDMLAEQLSATAEAHGTAQQVCEAAEAAAAQATESVDAARVQL
: * : : .: .: . :
Mflv_2256|M.gilvum_PYR-GCK DAARGAVQRLADREEVDRLAGRIATIERHQRELDAVSGELAAIALTDPLM
Mvan_4435|M.vanbaalenii_PYR-1 DAARVAVQRLADREEADRLTGRIATIERHGRELEAVQRDLTAITLTDALL
MSMEG_5002|M.smegmatis_MC2_155 DAARAAVERLSDRDEADRLDMRLAKIDAATRELQAVTDELKTITLDDTAM
TH_1853|M.thermoresistible__bu DTARQAVQRLADRAERDTLADRLRRIDAAATELARVDGELATLTVTEAAL
Mb1309|M.bovis_AF2122/97 ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
Rv1278|M.tuberculosis_H37Rv ESARRTLDQLADCEEADRLAARLARIDDIEGDRDRVCAELSAVTLTEELL
MUL_4005|M.ulcerans_Agy99 EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MMAR_4142|M.marinum_M EAARRSLDQIADREQAQRLSARLARIGEVQCDHDRVCAQLSEVTLTEALL
MLBr_01120|M.leprae_Br4923 DIARSTVDQLVDRQEADRLSTRLAKIDAIQGERDLICAELSAVTLTEQLL
MAV_1428|M.avium_104 QEAQRTVERSAGREEADRLAARLDKIDAIQRDRERISAELSTIAVTEELL
MAB_1421|M.abscessus_ATCC_1997 EAARGTLDRALARDEVDGLAARVSRIDLTNRQLASVGAELSSLVITAQSL
: *: :::: : : * *: * : : :* :.: :
Mflv_2256|M.gilvum_PYR-GCK TAIEKAAAVVDRATAAVAYASARMELVAAADLEISVDGSTVTLNAGDTWS
Mvan_4435|M.vanbaalenii_PYR-1 ADIETAAAAVERATAAVEQTSAHIEVTAAADVEVRIGDADMTLRAGDTWA
MSMEG_5002|M.smegmatis_MC2_155 RAIEKAALAVERAAGQAELASARIELVAQNGLDVRVDDATVALQAGAEWS
TH_1853|M.thermoresistible__bu RQIEAAELAVERAAGQAELASAHIELTAAVDLELRVGDEQLTIPAGGSWT
Mb1309|M.bovis_AF2122/97 SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
Rv1278|M.tuberculosis_H37Rv SRIERAAAAVDRGGAQLASISAAVEFTAAVDIELGVGDQRVSLSAGQSWS
MUL_4005|M.ulcerans_Agy99 KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVDGQRVQLSAGLSWS
MMAR_4142|M.marinum_M KRIESAAASVDRVDGQLALISAAVEFTAAADIELVVGGQRVQLSAGSSWS
MLBr_01120|M.leprae_Br4923 QRIENAAAIVDRTGEQLKLISAAVEFTATADIEISVGQQRVSLEAGQSWS
MAV_1428|M.avium_104 RRIEDAAAAVDRIGDQLASTSAAVEFTAVADIHLVIGDRQVSLPAGQSWS
MAB_1421|M.abscessus_ATCC_1997 GAIETAARAVGMAEAALETASAQVELRALVDVDIAVNGEQLRVAAGDRWS
** * * ** :*. * .:.: :. : : ** *:
Mflv_2256|M.gilvum_PYR-GCK AGVSADTGVDVAGVLSLRITPGASASATQSELDDATAALSDALAQAGVAD
Mvan_4435|M.vanbaalenii_PYR-1 AAVGTATGIDLPGVLSVQVIPGASAAATAAALDTAAARLADALRAAGVDD
MSMEG_5002|M.smegmatis_MC2_155 VSTTTRTEIDVPGVLSVRVVPGTPAAETQARLDDAQAVLTAALQAVGAES
TH_1853|M.thermoresistible__bu AGATAPTEIELPGLLTARIVPGAPAAQMQETLDVARAALADALQHAGVAD
Mb1309|M.bovis_AF2122/97 VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
Rv1278|M.tuberculosis_H37Rv VTATGPTEVKVPGVLTARIVPGATALDFQAKYAAAQQELADALAAGEVAD
MUL_4005|M.ulcerans_Agy99 MTATGPAEVEVPGVLTARIIQGATALEAQAKYVAAQEELAVALAAGGVAT
MMAR_4142|M.marinum_M MTATGPAEVEVPGVLTARITQGATALEAQAKYVAAQEELAVALAAGGVAT
MLBr_01120|M.leprae_Br4923 TTATGPTEVEVLGVLTACVIPGATALDAQSKYVAAQEELSVALADGGVVD
MAV_1428|M.avium_104 ITAVGPTAVEVPGVLTARVTPGATTLDVQAKHAAAQQELAAALTAGAVAD
MAB_1421|M.abscessus_ATCC_1997 SAATDTIEITAPGVAVARIIPGPNAAQLRDKLDTARQTLSGALADAGVAD
. : *: : *. : * *: ** .
Mflv_2256|M.gilvum_PYR-GCK LAAARALDAHRQQLCGARRQVSAILDALTAEDSVADLQTRLTAVQARIP-
Mvan_4435|M.vanbaalenii_PYR-1 VEAARALDRRRHELSAAGRQIRAILEALAADDSVDQLRARLADLQARTP-
MSMEG_5002|M.smegmatis_MC2_155 VDVARALDARRRELLGSRDRLRATLDALVGDDDIARLRDRLAALRAGQT-
TH_1853|M.thermoresistible__bu VASARSQVERRRELSTARETFAATVVALTGEDTLERLRARLAELDAAAS-
Mb1309|M.bovis_AF2122/97 LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
Rv1278|M.tuberculosis_H37Rv LAAARSADLCRRELLSRRDQLTATLAGLCGDEQVDQLRSRLEQLCAGQP-
MUL_4005|M.ulcerans_Agy99 LAEARSVEQRRRELLGRRDQLNATLAGLCGDEQVDQLRCRLAQLQASQP-
MMAR_4142|M.marinum_M LAEARSVEQRRRELLGRRDQLSATLAGLCGDEQVDQLRCRLAQLQASQP-
MLBr_01120|M.leprae_Br4923 LAAARCANQRRRELQSSLDQLSAALAGVCGDDQIDQLRARLEQLRDGYP-
MAV_1428|M.avium_104 LGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDELRSRLARLRAEHPE
MAB_1421|M.abscessus_ATCC_1997 VGEAQKQFERRTELNAERDRLTALLDGLMGPESLEALREKLSRLRELVP-
: *: * :* . * : .: . : : *: :* : .
Mflv_2256|M.gilvum_PYR-GCK --AADGLFDTDA-AILDPAAQRLELIEATAAHQDAIRDCETHRKVADQAG
Mvan_4435|M.vanbaalenii_PYR-1 --AEEGLFDTDTRGSLDPAAQRLELVEATAAHQQAIRDCETHRKVAEEAA
MSMEG_5002|M.smegmatis_MC2_155 --DDGGLFDVEGPADID--TARAQLAADVAAHREAVAHCETARKAVAVAA
TH_1853|M.thermoresistible__bu --DDTGELGVDD--------AQAELTAAERAYQQAHTDCETHRKAAVLAA
Mb1309|M.bovis_AF2122/97 --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
Rv1278|M.tuberculosis_H37Rv --AELDLVSTDT------ATARAELDAVEAARIAAEKDCETRRQIAAGAA
MUL_4005|M.ulcerans_Agy99 --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLAVAAS
MMAR_4142|M.marinum_M --AEPDLFATDA------TAARAELEAAEAARITAGKQCEDQRKLALAAS
MLBr_01120|M.leprae_Br4923 --GEPDLLAVDI------GSARAELEAAETVRAAVDFEREVCRRTAAAAN
MAV_1428|M.avium_104 QPAAPTGGAADL------AAARTELEALAQARACASAECVTRRQAATAAA
MAB_1421|M.abscessus_ATCC_1997 --EATGLWDAIDP-----AQARAEVARLVGEVERLQAEEVTHRRAVQTAG
. : :: . *: . *
Mflv_2256|M.gilvum_PYR-GCK KLVAQRELNAARIAQKLQSAQHELTTIAARLAEQRASVGDEELALKTDAD
Mvan_4435|M.vanbaalenii_PYR-1 KLSAKRGLHAARLLEKLQAAQAELAAAGARLAEQRAATSDDELAVKAEAD
MSMEG_5002|M.smegmatis_MC2_155 ARDTEKSTRLSVLREKLTAAQTELTTCSARLEAQRAGTPDEALALKVQAD
TH_1853|M.thermoresistible__bu RRLAEKSQTAAALREKLTAARTELDTAAARLAAQRADVDDETLVVRAAAH
Mb1309|M.bovis_AF2122/97 RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
Rv1278|M.tuberculosis_H37Rv RRLAETSTRATVLQNAAAAESAELGAAMTRLACERASVGDDELAAKAEAD
MUL_4005|M.ulcerans_Agy99 RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MMAR_4142|M.marinum_M RRLAETSTSATVLQSRLENGRAEVEAATSRLATARAAVSDADLASAADAD
MLBr_01120|M.leprae_Br4923 CRLVETSARANFLLKKAETQRAELDQDIDQLAQQRASVSDEDLASAAEAG
MAV_1428|M.avium_104 ARLAETATAATVLQNRLDTLRAELDAATGRLAAERASVGDEELAASADAA
MAB_1421|M.abscessus_ATCC_1997 QQLAEKAAEAMAAREKHAARAEELAAAEQRLAHVRSSASDDLLTERHERA
.: . *: :* *: . * *.
Mflv_2256|M.gilvum_PYR-GCK AETAAKAVAAVAELRDELARHHPDAVVAALAEAERALATVTARRDEAVEA
Mvan_4435|M.vanbaalenii_PYR-1 AEAAAAAEAAVARVGAELAGHEPEAVAAALVDAERAAAEVGARHHEVGEA
MSMEG_5002|M.smegmatis_MC2_155 DEQAKATAARVATLRDELDRSAPDSVLAELADAQRHAQSVQTRHDAATEG
TH_1853|M.thermoresistible__bu GEEAERAAVRVAQLNAELSAAQPDQVAAALDTAARHAETVHAEHRRTADA
Mb1309|M.bovis_AF2122/97 LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
Rv1278|M.tuberculosis_H37Rv LRVLQTAEQRVIDLADELAATAPDAVAAELAEAADAVELLRERHDEAIRA
MUL_4005|M.ulcerans_Agy99 LHVLQASQRRLAELTEVLDAAEPEAVAAEAREAAEIAQSLGERHDAVVAA
MMAR_4142|M.marinum_M LHVLQASQRRLAELAEVLDAAEPEAVAAELREAAEIAQSLDERHDAVVAA
MLBr_01120|M.leprae_Br4923 LRAVQIAEQRVAKLTEELVAAEPEAVTAELVAATAAAESLRDQHEDAAGA
MAV_1428|M.avium_104 LRAEQAAERRVAELADALAAASPDSVAAELADATQESESLRERYEEAAGA
MAB_1421|M.abscessus_ATCC_1997 VQAADLTSRRVTDLVSQLAALEADRVRAELAEVSARAQALDRRHEATRDR
. : : : * .: * * . : . .
Mflv_2256|M.gilvum_PYR-GCK LREIAAQLKVFGTEGRKGNLDAAETERERAEAEFGRVQRRARAAQLLRTV
Mvan_4435|M.vanbaalenii_PYR-1 LREIAAQLKVYGTEGRKGGLDAAETERGRAEAEFVRVQRRARAAELLRSV
MSMEG_5002|M.smegmatis_MC2_155 LREVSAQLKVYGTEGRKGQLDEAETEREHANAEYLRVHRRARAAELLRSV
TH_1853|M.thermoresistible__bu LRELNAQLEVYGSEGRKGELDAAKAEREQAEAEFLRIGRLARAVKLLRET
Mb1309|M.bovis_AF2122/97 LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
Rv1278|M.tuberculosis_H37Rv LHEVGVELSVFGTQGRKGKLDAAETEREHAASHHARVGRRARAARLLRSV
MUL_4005|M.ulcerans_Agy99 LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MMAR_4142|M.marinum_M LRDISVELSVFGSEGRQSKLDAAETEREHAASQHARIGRRARAAQLLRSV
MLBr_01120|M.leprae_Br4923 LREISIELSVFGTEGRQGKLDTAEAEREHAISQHTQIGRRARAAQLLRSV
MAV_1428|M.avium_104 LREVTIELSVFGSEGRQGKLDAAETEREHAASEHSQVGRRARAAQLLRSV
MAB_1421|M.abscessus_ATCC_1997 LRDISVRLEVFGRQGRQDQLDAAASEREYAATEFARIGAKARAVDTLRSV
*::: .*.*:* :**:. ** * :** * :.. :: ***. ** .
Mflv_2256|M.gilvum_PYR-GCK MGRHRDAMRQRYVDPFRTEVERLGRIVFGDTFEVDVDSELRIGHRTLSGR
Mvan_4435|M.vanbaalenii_PYR-1 MGRHRDAMRQRYVDPFRGEVERLGRIVFGDSFEVDVDSSLCIGNRTLSGR
MSMEG_5002|M.smegmatis_MC2_155 MTRHRDATRQRYVDPFRNEVQRLGRLVFGEDFEVDVDSKLRISTRTVSGR
TH_1853|M.thermoresistible__bu MLRHRDASRRRYVDPFRAEVERLGRIVFGDSFEVEIDSDLCIRSRTLAGR
Mb1309|M.bovis_AF2122/97 MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
Rv1278|M.tuberculosis_H37Rv MARHRDTTRLRYVEPYRAELHRLGRPVFGPSFEVEVDTDLRIRSRTLDDR
MUL_4005|M.ulcerans_Agy99 MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MMAR_4142|M.marinum_M MTRHRDTTRQRYVEPYRMELQRLGRPVFGPTFEVDVGSDLRIRSRTLDDV
MLBr_01120|M.leprae_Br4923 MARHRDTTRLRYVEPYRTELQRLGRPVFGPTFEVDIDSDLRIRSRTLDGI
MAV_1428|M.avium_104 MTRHRDTTRQRYVEPYRAELQRLGRPVFGPTFEVDIDSDLCIRSRTLNGI
MAB_1421|M.abscessus_ATCC_1997 MMRHRDGMRLRYVDPFRAELERLGRMVFGPTFEVDIDSDLSIRSRTLEGR
* **** * ***:*:* *:.**** *** ***::.:.* * **: .
Mflv_2256|M.gilvum_PYR-GCK TVPYESLSGGAKEQLGIVARLAGATLVASEDSVPVVIDDALGFTDADRLT
Mvan_4435|M.vanbaalenii_PYR-1 TVPYESLSGGAKEQLGIVARLAGAALVAKEDSVPVVIDDALGFTDTERLT
MSMEG_5002|M.smegmatis_MC2_155 TVPYESLSGGAKEQLAIVARLAGASLVAKEDTVPVIIDDALGFTDADRLT
TH_1853|M.thermoresistible__bu TVDYESLSGGAKEQLGIVARLAGAALVARDDTVPVVIDDALGFTDAERLV
Mb1309|M.bovis_AF2122/97 TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
Rv1278|M.tuberculosis_H37Rv TVPYECLSGGAKEQLGILARLAGAALVAKEDAVPVLIDDALGFTDPERLA
MUL_4005|M.ulcerans_Agy99 TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MMAR_4142|M.marinum_M TVPYESLSGGAKEQLGILARFAGAALVAKEDTVPVVVDDALGFTDPDRLA
MLBr_01120|M.leprae_Br4923 TVPFESLSGGAKEQLGILARFAGATLVAKEDNVPVVVDDALGFTDPDRLA
MAV_1428|M.avium_104 TVPYESLSGGAKEQLGILARLAGAALVAKEDAVPVVVDDALGFTDPDRLA
MAB_1421|M.abscessus_ATCC_1997 TVPYESLSGGAKEQLGIVARLASAALVAPQDAVPVIIDDALGFTDSDRLE
** :*.*********.*:**:*.*:*** :* ***::********.:**
Mflv_2256|M.gilvum_PYR-GCK KMAEVFDAVAGDGQVIILTCSPQRYADVRSARHIELVAG-
Mvan_4435|M.vanbaalenii_PYR-1 KMAEVFDAVAGDGQVIILTCSPQRYAGVRTAQHIELIAG-
MSMEG_5002|M.smegmatis_MC2_155 KMGAVFDAVGGDGQVIVLTCSPDRYASVHGAHHIALTA--
TH_1853|M.thermoresistible__bu KMGAVFDAVGGDGQVIVLTCSPDRYAGISDAHRIELTA--
Mb1309|M.bovis_AF2122/97 KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
Rv1278|M.tuberculosis_H37Rv KMGEVFDTIGADGQVIVLTCSPTRYGGVKGAHRIDLDAIQ
MUL_4005|M.ulcerans_Agy99 KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MMAR_4142|M.marinum_M KMGGVFDTVGTHGQVIVLTCSPDRYDGVAGAHRIDLNL--
MLBr_01120|M.leprae_Br4923 KMGEMFDTVGAHGQVIVLTCSPDRYDGFTGAHRIDLNV--
MAV_1428|M.avium_104 KMGQLFDSVGSHGQVIVLTCSPDRYDGVKGAHRIDLSA--
MAB_1421|M.abscessus_ATCC_1997 RMGEVFGAVGTETQVIVLTCSPDRYRAVTGAQRISLSA--
:*. :*.::. . ***:***** ** . *::* *