For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTASELSIPQDWDEITPAWMTSALAQHFPGAEVGHVRVALRDDGTNRRARLALDYSVGSGPATVFAKAVD PAHADLVELTSGLYHEPRLFSCGARLPLDHPEVYLAAIDEERRDFLMIMEDVASRGADPRDSTRPMTVEQ AAAGVRGLARLHGEYWGERLTGDPALNWVEPFVAFEGLEYAPLHIAHERLGDTVPAEVLDLSGTDLFVDI WARYIGSLTRSVPTLLHGDPHIGNTYVLPDGTVGFLDWQMVRRGSFSLDLGYFLQGSLTTEDRRRAEHDL LDEYRAALRLPAQELPTREDIWLGYRASVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVDLDTRE ALDAIT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4223 | - | - | 100% (356) | hypothetical protein Mvan_4223 |
| M. vanbaalenii PYR-1 | Mvan_2228 | - | 1e-29 | 33.43% (356) | aminoglycoside phosphotransferase |
| M. vanbaalenii PYR-1 | Mvan_3433 | - | 8e-22 | 29.17% (336) | aminoglycoside phosphotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 3e-05 | 32.08% (106) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_2429 | - | 1e-167 | 85.12% (336) | hypothetical protein Mflv_2429 |
| M. tuberculosis H37Rv | Rv3197 | - | 3e-05 | 32.08% (106) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0395 | - | 2e-29 | 33.53% (343) | hypothetical protein MMAR_0395 |
| M. avium 104 | MAV_2666 | - | 4e-40 | 34.52% (365) | hypothetical protein MAV_2666 |
| M. smegmatis MC2 155 | MSMEG_4885 | - | 1e-122 | 61.02% (354) | hypothetical protein MSMEG_4885 |
| M. thermoresistible (build 8) | TH_3005 | - | 2e-86 | 47.92% (361) | PUTATIVE putative protein of unknown function DUF227 |
| M. ulcerans Agy99 | MUL_1045 | - | 2e-28 | 33.52% (352) | hypothetical protein MUL_1045 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4223|M.vanbaalenii_PYR-1 ----------MTASELSIPQD-WDEITPAWMT-------------SALAQ
Mflv_2429|M.gilvum_PYR-GCK ------------------------------MT-------------SALAQ
MSMEG_4885|M.smegmatis_MC2_155 -----------MTAALTVPRD-WTEITPQWLT-------------AALAT
TH_3005|M.thermoresistible__bu ----------MVHPALTIPPR-WEDVTPEWMT-------------AAIST
MAV_2666|M.avium_104 ----------MTGQALHVTLQSAEDITPAILT-------------SLLRR
MMAR_0395|M.marinum_M --MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALS
MUL_1045|M.ulcerans_Agy99 -------MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALS
Mb3220|M.bovis_AF2122/97 MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAE
Rv3197|M.tuberculosis_H37Rv MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAE
Mvan_4223|M.vanbaalenii_PYR-1 HFPGAEVGHVRVALRDDGTNRRARLALDYSVG------SGPATVFAKAVD
Mflv_2429|M.gilvum_PYR-GCK HFPGAEVDSVQVALRDDGTNRRARLALTYSAG------SGPATVFAKAVD
MSMEG_4885|M.smegmatis_MC2_155 HHPGAVVEGVGVDMRDDGTNRRARLAVTYRPGP-----AGPATLFVKAVD
TH_3005|M.thermoresistible__bu RHPGATVERVTLLLRDDGTNRRARFELAYASG------TGPRRVFVKAES
MAV_2666|M.avium_104 HDPEATVTRVTIGHTWQGTTSHLHLDVAYADPQT----RLPQRLFIKTQL
MMAR_0395|M.marinum_M EIMGRRVSSVSVLDDSSGTTSRARLALSGNDV--------PESVFVKMAA
MUL_1045|M.ulcerans_Agy99 EIMGRRVSSVSVLDDSSGTTSRARLALSGNDV--------PESVFVKMAA
Mb3220|M.bovis_AF2122/97 LMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQ
Rv3197|M.tuberculosis_H37Rv LMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQ
. : .* : : * .
Mvan_4223|M.vanbaalenii_PYR-1 ------PAHADLVELTSG----LYHEPRLF----SCGARLPLDHPEVYLA
Mflv_2429|M.gilvum_PYR-GCK ------PEHADLVALTSG----LYHEPRLF----SSGVALPLDHPTVYTA
MSMEG_4885|M.smegmatis_MC2_155 ------PDHKAMIKMTSG----LLHEPRLF----NSDVALPLEHPTVYAA
TH_3005|M.thermoresistible__bu G----VPGRREIHYENGN----LFNESWLYRALLDGRTELPLEHPRAYAV
MAV_2666|M.avium_104 GTVHDLPEAFDESLSEGGGGTVLYDDETRFYR--DLRPDLSVETMTTYFA
MMAR_0395|M.marinum_M A-----TAATRFIGELGR----LAETEVSFYR--DLSPELAPDAPTAYGC
MUL_1045|M.ulcerans_Agy99 A-----TAATRFIGELGR----LAETEVSFYR--DLSPELAPDAPTAYGC
Mb3220|M.bovis_AF2122/97 KDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSD
Rv3197|M.tuberculosis_H37Rv KDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSD
. . . : : :
Mvan_4223|M.vanbaalenii_PYR-1 AIDEER-RDFLMIMEDVASRGA---DPRDSTRPMTVEQAAAGVRGLARLH
Mflv_2429|M.gilvum_PYR-GCK LIDEDR-RDFLMIMEDVVARGA---DPRDSTRPMSVEQAAAGVRGLARLH
MSMEG_4885|M.smegmatis_MC2_155 AIDEAD-EEFVLVMEDLTARGA---DPRDATRPLTVDQAANGVRALARLH
TH_3005|M.thermoresistible__bu AIDESA-LDYVIVFEDLLERSA---DPRDPTRPLTADQVADGLQGLARLH
MAV_2666|M.avium_104 DHLDGP-SQFLILGEDITLRGA---QVPDAVAGLTVEQADALLATLSQLH
MMAR_0395|M.marinum_M AYDPLT-GRFVLVLEDLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLH
MUL_1045|M.ulcerans_Agy99 AFDPLT-GRFVLVLEDLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLH
Mb3220|M.bovis_AF2122/97 GREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVER
Rv3197|M.tuberculosis_H37Rv GREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVER
: * : . : : :
Mvan_4223|M.vanbaalenii_PYR-1 GEYWG-ERLTGDPALNWVEPFVA------FEGLEYAPLHIAHERLGDTVP
Mflv_2429|M.gilvum_PYR-GCK SEYWG-ERLSAHPDLGWVEPFVA------FEGLEYAPLHIAHERLGDSVP
MSMEG_4885|M.smegmatis_MC2_155 GQFWG-ERLR-HPTLAWLEPFEP------WDGMQWAPLPAALERLGDDAP
TH_3005|M.thermoresistible__bu SRHW--NRVGDEPELAWVQPFRP------TRGWT-APMTAALP-HGITAA
MAV_2666|M.avium_104 APFWGSRRLANGGDLSWLQDPVTGG---FAHFLRDNGFAIIRALVDAPYK
MMAR_0395|M.marinum_M ATYWVRLNHGGVRPFGWLYAASR------------DPSVPLVPTMLRASW
MUL_1045|M.ulcerans_Agy99 ATYWVRLNHGGVRPFGWRYAASR------------DPSVPLVPTMLRASW
Mb3220|M.bovis_AF2122/97 TEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWIEGVPM
Rv3197|M.tuberculosis_H37Rv TEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWIEGVPM
. :
Mvan_4223|M.vanbaalenii_PYR-1 AEVLDLSGTDL----FVDIWARYIGSLTRSVP--TLLHGDPHIGNTYVLP
Mflv_2429|M.gilvum_PYR-GCK AEVLALDGTEL----FVDVWARYIGTLMSLTP--TLLHGDPHIGNTYVLP
MSMEG_4885|M.smegmatis_MC2_155 PSVQALTIDHL----VEGVWKPYIRCLTASSEPQTLLHGDAHIGNTYLTP
TH_3005|M.thermoresistible__bu RDVLSDAVTHLDADGLVDVWTAYIGGLGTGPQ--TFLHGDPHIGNTYLLP
MAV_2666|M.avium_104 KALLDAAGTDMDG--MEAAFWRLQDRVAREPV--TVLHGDPHPRNTYVLP
MMAR_0395|M.marinum_M RRLGGHAAALLPGRDYVFEHYRAITGLIDAPP-HTVLHGDAHPGNWYFRS
MUL_1045|M.ulcerans_Agy99 RRLGGHAAALLPGRDFVFEHYRAITGLIDAPP-HTVLHGDAHPGNWYFRS
Mb3220|M.bovis_AF2122/97 AEIIRHGTTEQ----RDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLP
Rv3197|M.tuberculosis_H37Rv AEIIRHGTTEQ----RDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLP
: .:***.* * . .
Mvan_4223|M.vanbaalenii_PYR-1 DG---TVGFLDWQMVR--RGSFSLDLGYFLQGS----------------L
Mflv_2429|M.gilvum_PYR-GCK DD---TVGFLDWQMVR--RGSFSLDLGYFLQGA----------------L
MSMEG_4885|M.smegmatis_MC2_155 DG---DVGFLDWQVAR--RGNFAVDLGYFLQGA----------------L
TH_3005|M.thermoresistible__bu DD---TVGFLDWQVVR--SGHWSHDVGYFLQSA----------------L
MAV_2666|M.avium_104 DG---RMGLLDWQLIR--RGSWSHDVGYALIAA----------------L
MMAR_0395|M.marinum_M SGGPLAAGLLDWQAVR--LGHPARDLAYTLITG----------------M
MUL_1045|M.ulcerans_Agy99 SGGPLAAGLLDWQAIR--LGHPARDLAYTLITG----------------M
Mb3220|M.bovis_AF2122/97 DG---RMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGL
Rv3197|M.tuberculosis_H37Rv DG---RMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGL
.. *::*: * . ::. : . :
Mvan_4223|M.vanbaalenii_PYR-1 TTEDRRRAEHDLLDEYR-AALRLPAQELPTREDIWLGYRASVAHGLAIWM
Mflv_2429|M.gilvum_PYR-GCK TIEDRRSAERDLLAEYR-DALRLPSHERPSADDLWLHYRASVAHGLAIWM
MSMEG_4885|M.smegmatis_MC2_155 RTEDRRIAERELLQEYS-DALELPDAEKPSLEQIWLRYRASVAHGLMTWL
TH_3005|M.thermoresistible__bu TEADRRAHEAALLAHYR-NALQLPEIRRPTAEEAWLRYRASAAHGLPVWL
MAV_2666|M.avium_104 SPELRRAHERELLDNYRGRLLDAGVTSLPDRESMWTAYRQSPAWGFCMWA
MMAR_0395|M.marinum_M TTTDRRVTERELLDVYR-RALAAAGGPELDREELWLRYRQAAAY-AYVAT
MUL_1045|M.ulcerans_Agy99 TTTDRRVTERELLDVYR-RALAAAGGPELDREEPWLRYRQAAAC-AYVAT
Mb3220|M.bovis_AF2122/97 IQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQI
Rv3197|M.tuberculosis_H37Rv IQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQI
*: : . :
Mvan_4223|M.vanbaalenii_PYR-1 ATLSGGDAWQRADICLAFAQRYAAAFVDLDTREALDAIT-----------
Mflv_2429|M.gilvum_PYR-GCK ATLSGGDAWQRADICLAFAQRYAAAFVDLDTREALRSIGG----------
MSMEG_4885|M.smegmatis_MC2_155 ATASAGELWQRPDIALALAQRYSAAYEDLQTAEALADLTA----------
TH_3005|M.thermoresistible__bu ITLLS-DAHP-TERSRALVQRFAAAFTDLDTPAAVQTLRRT---------
MAV_2666|M.avium_104 I---APDQMYSVEVVGAVLGRFAEAYYDLGTGTVLS--------------
MMAR_0395|M.marinum_M TIVAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTS------
MUL_1045|M.ulcerans_Agy99 TIAAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAWRPG
Mb3220|M.bovis_AF2122/97 RTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPD
Rv3197|M.tuberculosis_H37Rv RTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPD
:* : :
Mvan_4223|M.vanbaalenii_PYR-1 --------------------------------------
Mflv_2429|M.gilvum_PYR-GCK --------------------------------------
MSMEG_4885|M.smegmatis_MC2_155 --------------------------------------
TH_3005|M.thermoresistible__bu --------------------------------------
MAV_2666|M.avium_104 --------------------------------------
MMAR_0395|M.marinum_M --------------------------------------
MUL_1045|M.ulcerans_Agy99 MARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW
Mb3220|M.bovis_AF2122/97 AIVV----------------------------------
Rv3197|M.tuberculosis_H37Rv AIVV----------------------------------