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PENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALSEIMGRRVSSVSVLDDSSGTTSRA RLALSGNDVPESVFVKMAAATAATRFIGELGRLAETEVSFYRDLSPELAPDAPTAYGCAYDPLTGRFVLV LEDLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLNHGGVRPFGWLYAASRDPSVPLVPTM LRASWRRLGGHAAALLPGRDYVFEHYRAITGLIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAVR LGHPARDLAYTLITGMTTTDRRVTERELLDVYRRALAAAGGPELDREELWLRYRQAAAYAYVATTIVAGL GGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0395 | - | - | 100% (389) | hypothetical protein MMAR_0395 |
M. marinum M | MMAR_4035 | - | 4e-15 | 26.02% (369) | hypothetical protein MMAR_4035 |
M. marinum M | MMAR_3019 | - | 6e-13 | 29.51% (288) | hypothetical protein MMAR_3019 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_4117 | - | 1e-117 | 58.36% (377) | hypothetical protein Mflv_4117 |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4910c | - | 2e-05 | 41.18% (51) | putative aminoglycoside phosphotransferase |
M. avium 104 | MAV_5276 | - | 1e-117 | 58.07% (384) | phosphotransferase enzyme family protein |
M. smegmatis MC2 155 | MSMEG_2554 | - | 1e-117 | 59.79% (378) | phosphotransferase enzyme family protein |
M. thermoresistible (build 8) | TH_3005 | - | 3e-29 | 32.95% (346) | PUTATIVE putative protein of unknown function DUF227 |
M. ulcerans Agy99 | MUL_1045 | - | 0.0 | 97.92% (384) | hypothetical protein MUL_1045 |
M. vanbaalenii PYR-1 | Mvan_2228 | - | 1e-125 | 61.27% (377) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0395|M.marinum_M --MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALS MUL_1045|M.ulcerans_Agy99 -------MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALS MAV_5276|M.avium_104 MKNPVGQAFSFLGLAAHLGRGAGRVSVDAVLGGRFGLPRTVDEIDPAVLS MSMEG_2554|M.smegmatis_MC2_155 MLSTVRRIPPALALAAHIGHGVQRVAADAALGGLRRFPRRISDLDAGCLS Mflv_4117|M.gilvum_PYR-GCK MSVLSERIAPAVGLASHLGRGVRRIGTDTLIGRLLPLPRTIGDLGPDAMS Mvan_2228|M.vanbaalenii_PYR-1 MTVITQRIARAAGLAAHLGRALGRIGTDALIGRARALPRTVADLDAAAMS TH_3005|M.thermoresistible__bu ------------------------MVHPALTIPPRWEDVTPEWMTAAIST MAB_4910c|M.abscessus_ATCC_199 -----------------------MAAPHHIDPKSVDFDVVSHWMDEQGLP : . MMAR_0395|M.marinum_M EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR MUL_1045|M.ulcerans_Agy99 EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR MAV_5276|M.avium_104 RVMGTTVRTVRVLSRDAGTSSRARLVLTGKD--VPDSVFVKVAAQTAATR MSMEG_2554|M.smegmatis_MC2_155 TIMGRTVRTLSVLGGDAGTSSRARLALSGDG--VPETVFVKLPAETAATR Mflv_4117|M.gilvum_PYR-GCK SLMGRSVTSVAVLDGDAGTSSRARLALTGDG--VPATVFVKMAAETVATR Mvan_2228|M.vanbaalenii_PYR-1 SVIGRAVTSVSVLDGDAGTSSRARLALTGDG--VPESVFVKMAAETVGTR TH_3005|M.thermoresistible__bu RHPGATVERVTLLLRDDGTNRRARFELAYASGTGPRRVFVKAESGVPGRR MAB_4910c|M.abscessus_ATCC_199 ---GGQLTDISAITG-GTQNIMVRFSRGGRE----------YVLRRPPKH * : : : . .*: : MMAR_0395|M.marinum_M FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAYDPLTGRFVLVLE MUL_1045|M.ulcerans_Agy99 FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAFDPLTGRFVLVLE MAV_5276|M.avium_104 LMGELGRLGCTEVRFYRQLAP---QVV-GVPYCYGAAFDAWTGRYLLVLE MSMEG_2554|M.smegmatis_MC2_155 LMGELGRLAHTEVRFYQQLAA---GLP-GVPRAHGSAFDALTGRFVLVLE Mflv_4117|M.gilvum_PYR-GCK LMGELGNLADTETRFYSRLSA---ELT-GVPRCHGSRFDPRTGRFVLILE Mvan_2228|M.vanbaalenii_PYR-1 LMGELGNLAETETRFYRELSP---ELTTGVPLSYGSAFDPYTGRYILVLE TH_3005|M.thermoresistible__bu EIHYENGNLFNESWLYRALLDGRTELPLEHPRAYAVAIDESALDYVIVFE MAB_4910c|M.abscessus_ATCC_199 LREASNNVIRREARLLGALRG---QGVPAPELIAACTDETVLGGAVFYLM . * : * . : :: : MMAR_0395|M.marinum_M DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP MUL_1045|M.ulcerans_Agy99 DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP MAV_5276|M.avium_104 DLPA---EACEFPDTLHPLSADQAGLVVELLADLHATFWNRLP-RDGRGP MSMEG_2554|M.smegmatis_MC2_155 DLAQ---EPCEFPDTLHPLDKDRAALTVELLARVHAAFWGRLPERSGRGP Mflv_4117|M.gilvum_PYR-GCK DLADASAGPCDFPDTLHPIDADRAALVVELLARLHATFWGRLPERRGTGP Mvan_2228|M.vanbaalenii_PYR-1 DLAG---GDCEFPDTLHPIDADRAALVVELLATVHATFWGRLPARGHAGP TH_3005|M.thermoresistible__bu DLLER---SADPRDPTRPLTADQVADGLQGLARLHSRHWNRVGDEPELAW MAB_4910c|M.abscessus_ATCC_199 EPVDGFNASVGLPELHAGNAEIRHQMGLEAVSGIAALGALDYQELGLDG- : : : :: :: : : MMAR_0395|M.marinum_M FGWLYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDYVFEHYRAITG MUL_1045|M.ulcerans_Agy99 FGWRYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITG MAV_5276|M.avium_104 LGWLYTPSGDVTSLLTGSLMHSSIKRLAERTSIPVRDGVFIADNYRAVAA MSMEG_2554|M.smegmatis_MC2_155 LGWLYSASGDDTSLLTGTLLKTSTRRLAERADIPVADGRFIDENYRAAAQ Mflv_4117|M.gilvum_PYR-GCK LGWLYSASEDSASLLTAPLLRTSARRLAERTALPVGRGRFIDENYRAAAA Mvan_2228|M.vanbaalenii_PYR-1 LGWLYSASGDSASLLTAPLLRTSARRLAERTPLPVHRGGFIDDNYRAIAS TH_3005|M.thermoresistible__bu VQPFRPTRGWTAPMTAALPHGITAARDVLSDAVTHLDADGLVDVWTAYIG MAB_4910c|M.abscessus_ATCC_199 ---YGNPDGFLERQVPRWLKELDSYAKHDGYPGPDIPGLQSVANWLERHR . : MMAR_0395|M.marinum_M LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAVRLGHPARDLAYT MUL_1045|M.ulcerans_Agy99 LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYT MAV_5276|M.avium_104 LIDTAPHTVMHGDAHPGNMYFHGG----KAGLLDWQAVRRGHPSRELAYT MSMEG_2554|M.smegmatis_MC2_155 LLDRPPHTVMHGDAHPGNLFFRNG----EAGLLDWQAVRRGHPGRELAYT Mflv_4117|M.gilvum_PYR-GCK LIDRGPHTVMHGDAHPGNLYFRAG----QAGLLDWQAVRRGHPSRELAYT Mvan_2228|M.vanbaalenii_PYR-1 LVDRPPHTVMHGDAHPGNLYFRDG----RAGLLDWQAVRRGHPGRELAYT TH_3005|M.thermoresistible__bu GLGTGPQTFLHGDPHIGNTYLLPDD---TVGFLDWQVVRSGHWSHDVGYF MAB_4910c|M.abscessus_ATCC_199 PSQWKPG-IMHGDFHLANMMFRNDG-PQLAAIVDWEMSTIGDPLLDLGWM * .:*** * .* : . ..::**: *. ::.: MMAR_0395|M.marinum_M LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREELWLRYRQAAAYAY MUL_1045|M.ulcerans_Agy99 LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAY MAV_5276|M.avium_104 LITSLTPEDRRATQRDLLDDYRRALAAAGGPQLDRDELWLRFRQAALYAY MSMEG_2554|M.smegmatis_MC2_155 LITSMTTTDRQAAEKDLLDEYRRALAAAGGPRLDADELWERYRLGAVYAY Mflv_4117|M.gilvum_PYR-GCK LTTSMTVEGRRGSQRDLLEVYRRALAAGGGPELDRDDLWDRYRQAALYPY Mvan_2228|M.vanbaalenii_PYR-1 LVTSMTTEDRRRSERDLLDVYRRALAASGGPELDGDQLWDRYRQGAMYPY TH_3005|M.thermoresistible__bu LQSALTEADRRAHEAALLAHYRNALQLPEIRRPTAEEAWLRYRASAAHGL MAB_4910c|M.abscessus_ATCC_199 LATWPSETDDASLGGALVQAGGLPTPQELVAHYAERTDRDLGAMDWYTVL * : : . *: . . MMAR_0395|M.marinum_M VATTIVAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTS--- MUL_1045|M.ulcerans_Agy99 VATTIAAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAW MAV_5276|M.avium_104 AAPLITAGMGGMQVEDIAMEGLRRGVAALEDLETVAALKSSL-------- MSMEG_2554|M.smegmatis_MC2_155 TAPVITAGLGGMQDDGIAVEGARRGVAALADLETVALLKKLL-------- Mflv_4117|M.gilvum_PYR-GCK VATLITVGMGGMQVEDIAMKGLERALEALDDLETVALLEKNL-------- Mvan_2228|M.vanbaalenii_PYR-1 VATLITAGMGGMQDDGIALKGLERSLHALDDLDTVALLEKSL-------- TH_3005|M.thermoresistible__bu PVWLITL-LSDAHPTERSRALVQRFAAAFTDLDTPAAVQTLRRT------ MAB_4910c|M.abscessus_ATCC_199 ACFKLGIILEGTHARACAGKAPVAVGDYLHGLTLQLFKRAVAITG----- : : . : : : .* . MMAR_0395|M.marinum_M ----------------------------------------- MUL_1045|M.ulcerans_Agy99 RPGMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW MAV_5276|M.avium_104 ----------------------------------------- MSMEG_2554|M.smegmatis_MC2_155 ----------------------------------------- Mflv_4117|M.gilvum_PYR-GCK ----------------------------------------- Mvan_2228|M.vanbaalenii_PYR-1 ----------------------------------------- TH_3005|M.thermoresistible__bu ----------------------------------------- MAB_4910c|M.abscessus_ATCC_199 -----------------------------------------