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TSALAQHFPGAEVDSVQVALRDDGTNRRARLALTYSAGSGPATVFAKAVDPEHADLVALTSGLYHEPRLF SSGVALPLDHPTVYTALIDEDRRDFLMIMEDVVARGADPRDSTRPMSVEQAAAGVRGLARLHSEYWGERL SAHPDLGWVEPFVAFEGLEYAPLHIAHERLGDSVPAEVLALDGTELFVDVWARYIGTLMSLTPTLLHGDP HIGNTYVLPDDTVGFLDWQMVRRGSFSLDLGYFLQGALTIEDRRSAERDLLAEYRDALRLPSHERPSADD LWLHYRASVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVDLDTREALRSIGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2429 | - | - | 100% (338) | hypothetical protein Mflv_2429 |
| M. gilvum PYR-GCK | Mflv_4117 | - | 4e-32 | 35.74% (333) | hypothetical protein Mflv_4117 |
| M. gilvum PYR-GCK | Mflv_4330 | - | 2e-20 | 29.91% (331) | hypothetical protein Mflv_4330 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0395 | - | 2e-29 | 33.52% (349) | hypothetical protein MMAR_0395 |
| M. avium 104 | MAV_1965 | - | 7e-34 | 37.73% (273) | hypothetical protein MAV_1965 |
| M. smegmatis MC2 155 | MSMEG_4885 | - | 1e-120 | 62.24% (339) | hypothetical protein MSMEG_4885 |
| M. thermoresistible (build 8) | TH_3005 | - | 1e-83 | 48.41% (347) | PUTATIVE putative protein of unknown function DUF227 |
| M. ulcerans Agy99 | MUL_1045 | - | 2e-28 | 33.05% (357) | hypothetical protein MUL_1045 |
| M. vanbaalenii PYR-1 | Mvan_4223 | - | 1e-167 | 85.12% (336) | hypothetical protein Mvan_4223 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0395|M.marinum_M MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALSEI
MUL_1045|M.ulcerans_Agy99 -----MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEI
Mflv_2429|M.gilvum_PYR-GCK -----------------------------------------MTSALAQHF
Mvan_4223|M.vanbaalenii_PYR-1 ----------------------MTASELSIPQDWDEITPAWMTSALAQHF
MSMEG_4885|M.smegmatis_MC2_155 -----------------------MTAALTVPRDWTEITPQWLTAALATHH
TH_3005|M.thermoresistible__bu ----------------------MVHPALTIPPRWEDVTPEWMTAAISTRH
MAV_1965|M.avium_104 ---------------------------------------MTVTAVTVRHT
: . .
MMAR_0395|M.marinum_M MGRRVSSVSVLDDSSGTTSRARLALS---GNDVPESVFVKMAAATAATRF
MUL_1045|M.ulcerans_Agy99 MGRRVSSVSVLDDSSGTTSRARLALS---GNDVPESVFVKMAAATAATRF
Mflv_2429|M.gilvum_PYR-GCK PGAEVDSVQVALRDDGTNRRARLALTYSAG-SGPATVFAKAVD--PEHAD
Mvan_4223|M.vanbaalenii_PYR-1 PGAEVGHVRVALRDDGTNRRARLALDYSVG-SGPATVFAKAVD--PAHAD
MSMEG_4885|M.smegmatis_MC2_155 PGAVVEGVGVDMRDDGTNRRARLAVTYRPGPAGPATLFVKAVD--PDHKA
TH_3005|M.thermoresistible__bu PGATVERVTLLLRDDGTNRRARFELAYASG-TGPRRVFVKAESGVPGRRE
MAV_1965|M.avium_104 WQGTTSHVHLDVDYAEPDTQLPRHLFLK---SQLSTVHDLPEAVDVSLSE
. * : . : : :.
MMAR_0395|M.marinum_M IGELGRLAETEVSFYR---DLSPELAPDAPTAYGCAYDPLTGRFVLVLED
MUL_1045|M.ulcerans_Agy99 IGELGRLAETEVSFYR---DLSPELAPDAPTAYGCAFDPLTGRFVLVLED
Mflv_2429|M.gilvum_PYR-GCK LVALTSGLYHEPRLF----SSGVALPLDHPTVYTALIDEDRRDFLMIMED
Mvan_4223|M.vanbaalenii_PYR-1 LVELTSGLYHEPRLF----SCGARLPLDHPEVYLAAIDEERRDFLMIMED
MSMEG_4885|M.smegmatis_MC2_155 MIKMTSGLLHEPRLF----NSDVALPLEHPTVYAAAIDEADEEFVLVMED
TH_3005|M.thermoresistible__bu IHYENGNLFNESWLYRALLDGRTELPLEHPRAYAVAIDESALDYVIVFED
MAV_1965|M.avium_104 GGGGTVLLDDETRFYR---DLRSDLDIETMTTYFADYLNGPSQFLILGED
* :: . * : .* :::: **
MMAR_0395|M.marinum_M LAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWV-RLNH-----G
MUL_1045|M.ulcerans_Agy99 LAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWV-RLNH-----G
Mflv_2429|M.gilvum_PYR-GCK VVARGA---DPRDSTRPMSVEQAAAGVRGLARLHSEYWG-ERLSAHPDLG
Mvan_4223|M.vanbaalenii_PYR-1 VASRGA---DPRDSTRPMTVEQAAAGVRGLARLHGEYWG-ERLTGDPALN
MSMEG_4885|M.smegmatis_MC2_155 LTARGA---DPRDATRPLTVDQAANGVRALARLHGQFWG-ERLR-HPTLA
TH_3005|M.thermoresistible__bu LLERSA---DPRDPTRPLTADQVADGLQGLARLHSRHW--NRVGDEPELA
MAV_1965|M.avium_104 ITLRGA---QVPDAVAGLSVEQVDQLLTTLGRVHAAYWGSPRLEDGGDLS
: . : *. : :*. : *.*:*. .*
MMAR_0395|M.marinum_M GVRPFGWLYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDYVFEHYR
MUL_1045|M.ulcerans_Agy99 GVRPFGWRYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYR
Mflv_2429|M.gilvum_PYR-GCK WVEPFVAFEGLEYAPLHIAHERLGDSVPAEVLALDGTEL----FVDVWAR
Mvan_4223|M.vanbaalenii_PYR-1 WVEPFVAFEGLEYAPLHIAHERLGDTVPAEVLDLSGTDL----FVDIWAR
MSMEG_4885|M.smegmatis_MC2_155 WLEPFEPWDGMQWAPLPAALERLGDDAPPSVQALTIDHL----VEGVWKP
TH_3005|M.thermoresistible__bu WVQPFRPTRGWT-APMTAALP-HGITAARDVLSDAVTHLDADGLVDVWTA
MAV_1965|M.avium_104 WLQHPLTGGFADFLRINGFAIIRAFLEIPYKQALLDSAGADADAMEATFW
:.
MMAR_0395|M.marinum_M AITGLIDAPP-HTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAVRLGHPAR
MUL_1045|M.ulcerans_Agy99 AITGLIDAPP-HTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPAR
Mflv_2429|M.gilvum_PYR-GCK YIGTLMSLTP--TLLHGDPHIGNTYVLPDD---TVGFLDWQMVRRGSFSL
Mvan_4223|M.vanbaalenii_PYR-1 YIGSLTRSVP--TLLHGDPHIGNTYVLPDG---TVGFLDWQMVRRGSFSL
MSMEG_4885|M.smegmatis_MC2_155 YIRCLTASSEPQTLLHGDAHIGNTYLTPDG---DVGFLDWQVARRGNFAV
TH_3005|M.thermoresistible__bu YIGGLGTGPQ--TFLHGDPHIGNTYLLPDD---TVGFLDWQVVRSGHWSH
MAV_1965|M.avium_104 KLQERVARDP-ITLLHGDPHPRNTYALPDG---TMGVLDWQLVRRGSWSH
: *.****.* * * ... *.**** * * :
MMAR_0395|M.marinum_M DLAYTLITGMTTTDRRVTERELLDVYRRALAAAGGP-ELDREELWLRYRQ
MUL_1045|M.ulcerans_Agy99 DLAYTLITGMTTTDRRVTERELLDVYRRALAAAGGP-ELDREEPWLRYRQ
Mflv_2429|M.gilvum_PYR-GCK DLGYFLQGALTIEDRRSAERDLLAEYRDALRLPSHE-RPSADDLWLHYRA
Mvan_4223|M.vanbaalenii_PYR-1 DLGYFLQGSLTTEDRRRAEHDLLDEYRAALRLPAQE-LPTREDIWLGYRA
MSMEG_4885|M.smegmatis_MC2_155 DLGYFLQGALRTEDRRIAERELLQEYSDALELPDAE-KPSLEQIWLRYRA
TH_3005|M.thermoresistible__bu DVGYFLQSALTEADRRAHEAALLAHYRNALQLPEIR-RPTAEEAWLRYRA
MAV_1965|M.avium_104 DVGYALIGALPPDLRRAHERELLDNYRGRLVDAGVTSVPDREQMWTAYRE
*:.* * .: ** * ** * * . :: * **
MMAR_0395|M.marinum_M AAAY-AYVATTIVAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADL
MUL_1045|M.ulcerans_Agy99 AAAC-AYVATTIAAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADL
Mflv_2429|M.gilvum_PYR-GCK SVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVDLDTREALRSIGG
Mvan_4223|M.vanbaalenii_PYR-1 SVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVDLDTREALDAIT-
MSMEG_4885|M.smegmatis_MC2_155 SVAHGLMTWLATASAGELWQRPDIALALAQRYSAAYEDLQTAEALADLTA
TH_3005|M.thermoresistible__bu SAAHGLPVWLITLLS-DAHP-TERSRALVQRFAAAFTDLDTPAAVQTLRR
MAV_1965|M.avium_104 SPAWGFCMWAITPDQ---MYSVDIVTAVLGRFAEAYSDLGTGKLLCS---
: * : : * ** * :
MMAR_0395|M.marinum_M GGTS--------------------------------------------
MUL_1045|M.ulcerans_Agy99 GGTSWAWRPGMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW
Mflv_2429|M.gilvum_PYR-GCK ------------------------------------------------
Mvan_4223|M.vanbaalenii_PYR-1 ------------------------------------------------
MSMEG_4885|M.smegmatis_MC2_155 ------------------------------------------------
TH_3005|M.thermoresistible__bu T-----------------------------------------------
MAV_1965|M.avium_104 ------------------------------------------------