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TGQALHVTLQSAEDITPAILTSLLRRHDPEATVTRVTIGHTWQGTTSHLHLDVAYADPQTRLPQRLFIKT QLGTVHDLPEAFDESLSEGGGGTVLYDDETRFYRDLRPDLSVETMTTYFADHLDGPSQFLILGEDITLRG AQVPDAVAGLTVEQADALLATLSQLHAPFWGSRRLANGGDLSWLQDPVTGGFAHFLRDNGFAIIRALVDA PYKKALLDAAGTDMDGMEAAFWRLQDRVAREPVTVLHGDPHPRNTYVLPDGRMGLLDWQLIRRGSWSHDV GYALIAALSPELRRAHERELLDNYRGRLLDAGVTSLPDRESMWTAYRQSPAWGFCMWAIAPDQMYSVEVV GAVLGRFAEAYYDLGTGTVLS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2666 | - | - | 100% (372) | hypothetical protein MAV_2666 |
| M. avium 104 | MAV_1965 | - | e-165 | 79.35% (339) | hypothetical protein MAV_1965 |
| M. avium 104 | MAV_5276 | - | 2e-30 | 30.89% (327) | phosphotransferase enzyme family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2429 | - | 7e-33 | 32.23% (363) | hypothetical protein Mflv_2429 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0395 | - | 2e-26 | 29.63% (351) | hypothetical protein MMAR_0395 |
| M. smegmatis MC2 155 | MSMEG_4885 | - | 6e-36 | 32.79% (366) | hypothetical protein MSMEG_4885 |
| M. thermoresistible (build 8) | TH_3005 | - | 5e-39 | 33.52% (361) | PUTATIVE putative protein of unknown function DUF227 |
| M. ulcerans Agy99 | MUL_1045 | - | 3e-26 | 29.62% (368) | hypothetical protein MUL_1045 |
| M. vanbaalenii PYR-1 | Mvan_4223 | - | 5e-40 | 34.52% (365) | hypothetical protein Mvan_4223 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2429|M.gilvum_PYR-GCK ----------------------------MT-------------SALAQHF
Mvan_4223|M.vanbaalenii_PYR-1 --------MTASELSIPQD-WDEITPAWMT-------------SALAQHF
MSMEG_4885|M.smegmatis_MC2_155 ---------MTAALTVPRD-WTEITPQWLT-------------AALATHH
TH_3005|M.thermoresistible__bu --------MVHPALTIPPR-WEDVTPEWMT-------------AAISTRH
MAV_2666|M.avium_104 --------MTGQALHVTLQSAEDITPAILT-------------SLLRRHD
MMAR_0395|M.marinum_M MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALSEI
MUL_1045|M.ulcerans_Agy99 -----MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEI
: . .
Mflv_2429|M.gilvum_PYR-GCK PGAEVDSVQVALRDDGTNRRARLALTYSAG--SGPATVFAKAVD------
Mvan_4223|M.vanbaalenii_PYR-1 PGAEVGHVRVALRDDGTNRRARLALDYSVG--SGPATVFAKAVD------
MSMEG_4885|M.smegmatis_MC2_155 PGAVVEGVGVDMRDDGTNRRARLAVTYRPGP-AGPATLFVKAVD------
TH_3005|M.thermoresistible__bu PGATVERVTLLLRDDGTNRRARFELAYASG--TGPRRVFVKAESG----V
MAV_2666|M.avium_104 PEATVTRVTIGHTWQGTTSHLHLDVAYADPQTRLPQRLFIKTQLGTVHDL
MMAR_0395|M.marinum_M MGRRVSSVSVLDDSSGTTSRARLALSGNDV----PESVFVKMAAA-----
MUL_1045|M.ulcerans_Agy99 MGRRVSSVSVLDDSSGTTSRARLALSGNDV----PESVFVKMAAA-----
* * : .**. : :: : * :* *
Mflv_2429|M.gilvum_PYR-GCK PEHADLVALTSG----LYHEPRLF----SSGVALPLDHPTVYTALIDEDR
Mvan_4223|M.vanbaalenii_PYR-1 PAHADLVELTSG----LYHEPRLF----SCGARLPLDHPEVYLAAIDEER
MSMEG_4885|M.smegmatis_MC2_155 PDHKAMIKMTSG----LLHEPRLF----NSDVALPLEHPTVYAAAIDEAD
TH_3005|M.thermoresistible__bu PGRREIHYENGN----LFNESWLYRALLDGRTELPLEHPRAYAVAIDESA
MAV_2666|M.avium_104 PEAFDESLSEGGGGTVLYDDETRFYR--DLRPDLSVETMTTYFADHLDGP
MMAR_0395|M.marinum_M TAATRFIGELGR----LAETEVSFYR--DLSPELAPDAPTAYGCAYDPLT
MUL_1045|M.ulcerans_Agy99 TAATRFIGELGR----LAETEVSFYR--DLSPELAPDAPTAYGCAFDPLT
. . * . : . *. : .*
Mflv_2429|M.gilvum_PYR-GCK RDFLMIMEDVVARGA---DPRDSTRPMSVEQAAAGVRGLARLHSEYWG-E
Mvan_4223|M.vanbaalenii_PYR-1 RDFLMIMEDVASRGA---DPRDSTRPMTVEQAAAGVRGLARLHGEYWG-E
MSMEG_4885|M.smegmatis_MC2_155 EEFVLVMEDLTARGA---DPRDATRPLTVDQAANGVRALARLHGQFWG-E
TH_3005|M.thermoresistible__bu LDYVIVFEDLLERSA---DPRDPTRPLTADQVADGLQGLARLHSRHW--N
MAV_2666|M.avium_104 SQFLILGEDITLRGA---QVPDAVAGLTVEQADALLATLSQLHAPFWGSR
MMAR_0395|M.marinum_M GRFVLVLEDLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRL
MUL_1045|M.ulcerans_Agy99 GRFVLVLEDLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRL
:::: **: . : *. : :*. : *::**. .*
Mflv_2429|M.gilvum_PYR-GCK RLSAHPDLGWVEPFVA---FEGLEYAPLHIAHERLGDSVPAEVLALDGTE
Mvan_4223|M.vanbaalenii_PYR-1 RLTGDPALNWVEPFVA---FEGLEYAPLHIAHERLGDTVPAEVLDLSGTD
MSMEG_4885|M.smegmatis_MC2_155 RLR-HPTLAWLEPFEP---WDGMQWAPLPAALERLGDDAPPSVQALTIDH
TH_3005|M.thermoresistible__bu RVGDEPELAWVQPFRP---TRGWT-APMTAALP-HGITAARDVLSDAVTH
MAV_2666|M.avium_104 RLANGGDLSWLQDPVTGGFAHFLRDNGFAIIRALVDAPYKKALLDAAGTD
MMAR_0395|M.marinum_M NHGGVRPFGWLYAASR---------DPSVPLVPTMLRASWRRLGGHAAAL
MUL_1045|M.ulcerans_Agy99 NHGGVRPFGWRYAASR---------DPSVPLVPTMLRASWRRLGGHAAAL
. : * :
Mflv_2429|M.gilvum_PYR-GCK L----FVDVWARYIGTLMSLTP--TLLHGDPHIGNTYVLPDD---TVGFL
Mvan_4223|M.vanbaalenii_PYR-1 L----FVDIWARYIGSLTRSVP--TLLHGDPHIGNTYVLPDG---TVGFL
MSMEG_4885|M.smegmatis_MC2_155 L----VEGVWKPYIRCLTASSEPQTLLHGDAHIGNTYLTPDG---DVGFL
TH_3005|M.thermoresistible__bu LDADGLVDVWTAYIGGLGTGPQ--TFLHGDPHIGNTYLLPDD---TVGFL
MAV_2666|M.avium_104 MDG--MEAAFWRLQDRVAREPV--TVLHGDPHPRNTYVLPDG---RMGLL
MMAR_0395|M.marinum_M LPGRDYVFEHYRAITGLIDAPP-HTVLHGDAHPGNWYFRSSGGPLAAGLL
MUL_1045|M.ulcerans_Agy99 LPGRDFVFEHYRAITGLIDAPP-HTVLHGDAHPGNWYFRSSGGPLAAGLL
: : *.****.* * *. ... *:*
Mflv_2429|M.gilvum_PYR-GCK DWQMVRRGSFSLDLGYFLQGALTIEDRRSAERDLLAEYR-DALRLPSHER
Mvan_4223|M.vanbaalenii_PYR-1 DWQMVRRGSFSLDLGYFLQGSLTTEDRRRAEHDLLDEYR-AALRLPAQEL
MSMEG_4885|M.smegmatis_MC2_155 DWQVARRGNFAVDLGYFLQGALRTEDRRIAERELLQEYS-DALELPDAEK
TH_3005|M.thermoresistible__bu DWQVVRSGHWSHDVGYFLQSALTEADRRAHEAALLAHYR-NALQLPEIRR
MAV_2666|M.avium_104 DWQLIRRGSWSHDVGYALIAALSPELRRAHERELLDNYRGRLLDAGVTSL
MMAR_0395|M.marinum_M DWQAVRLGHPARDLAYTLITGMTTTDRRVTERELLDVYR-RALAAAGGPE
MUL_1045|M.ulcerans_Agy99 DWQAIRLGHPARDLAYTLITGMTTTDRRVTERELLDVYR-RALAAAGGPE
*** * * : *:.* * .: ** * ** * *
Mflv_2429|M.gilvum_PYR-GCK PSADDLWLHYRASVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVD
Mvan_4223|M.vanbaalenii_PYR-1 PTREDIWLGYRASVAHGLAIWMATLSGGDAWQRADICLAFAQRYAAAFVD
MSMEG_4885|M.smegmatis_MC2_155 PSLEQIWLRYRASVAHGLMTWLATASAGELWQRPDIALALAQRYSAAYED
TH_3005|M.thermoresistible__bu PTAEEAWLRYRASAAHGLPVWLITLLS-DAHP-TERSRALVQRFAAAFTD
MAV_2666|M.avium_104 PDRESMWTAYRQSPAWGFCMWAI---APDQMYSVEVVGAVLGRFAEAYYD
MMAR_0395|M.marinum_M LDREELWLRYRQAAAY-AYVATTIVAGLGGMQAADIALTGLDLTVAALHD
MUL_1045|M.ulcerans_Agy99 LDREEPWLRYRQAAAC-AYVATTIAAGLGGMQAADIALTGLDLTVAALHD
:. * ** : * . : : * *
Mflv_2429|M.gilvum_PYR-GCK LDTREALRSIGG--------------------------------------
Mvan_4223|M.vanbaalenii_PYR-1 LDTREALDAIT---------------------------------------
MSMEG_4885|M.smegmatis_MC2_155 LQTAEALADLTA--------------------------------------
TH_3005|M.thermoresistible__bu LDTPAAVQTLRRT-------------------------------------
MAV_2666|M.avium_104 LGTGTVLS------------------------------------------
MMAR_0395|M.marinum_M LQTVAALRAADLGGTS----------------------------------
MUL_1045|M.ulcerans_Agy99 LQTVAALRAADLGGTSWAWRPGMARSARIRPGASARRCPMVWSTSSHILG
* * .:
Mflv_2429|M.gilvum_PYR-GCK ----------
Mvan_4223|M.vanbaalenii_PYR-1 ----------
MSMEG_4885|M.smegmatis_MC2_155 ----------
TH_3005|M.thermoresistible__bu ----------
MAV_2666|M.avium_104 ----------
MMAR_0395|M.marinum_M ----------
MUL_1045|M.ulcerans_Agy99 VSRHFAMGAW