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TVITQRIARAAGLAAHLGRALGRIGTDALIGRARALPRTVADLDAAAMSSVIGRAVTSVSVLDGDAGTSS RARLALTGDGVPESVFVKMAAETVGTRLMGELGNLAETETRFYRELSPELTTGVPLSYGSAFDPYTGRYI LVLEDLAGGDCEFPDTLHPIDADRAALVVELLATVHATFWGRLPARGHAGPLGWLYSASGDSASLLTAPL LRTSARRLAERTPLPVHRGGFIDDNYRAIASLVDRPPHTVMHGDAHPGNLYFRDGRAGLLDWQAVRRGHP GRELAYTLVTSMTTEDRRRSERDLLDVYRRALAASGGPELDGDQLWDRYRQGAMYPYVATLITAGMGGMQ DDGIALKGLERSLHALDDLDTVALLEKSL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2228 | - | - | 100% (380) | aminoglycoside phosphotransferase |
| M. vanbaalenii PYR-1 | Mvan_4223 | - | 1e-29 | 33.43% (356) | hypothetical protein Mvan_4223 |
| M. vanbaalenii PYR-1 | Mvan_3433 | - | 6e-21 | 27.78% (360) | aminoglycoside phosphotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4117 | - | 1e-169 | 78.07% (383) | hypothetical protein Mflv_4117 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0395 | - | 1e-125 | 61.27% (377) | hypothetical protein MMAR_0395 |
| M. avium 104 | MAV_5276 | - | 1e-140 | 66.30% (368) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_2554 | - | 1e-149 | 68.80% (375) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_3005 | - | 3e-28 | 32.08% (346) | PUTATIVE putative protein of unknown function DUF227 |
| M. ulcerans Agy99 | MUL_1045 | - | 1e-122 | 61.02% (372) | hypothetical protein MUL_1045 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0395|M.marinum_M --MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALS
MUL_1045|M.ulcerans_Agy99 -------MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALS
Mvan_2228|M.vanbaalenii_PYR-1 MTVITQRIARAAGLAAHLGRALGRIGTDALIGRARALPRTVADLDAAAMS
Mflv_4117|M.gilvum_PYR-GCK MSVLSERIAPAVGLASHLGRGVRRIGTDTLIGRLLPLPRTIGDLGPDAMS
MSMEG_2554|M.smegmatis_MC2_155 MLSTVRRIPPALALAAHIGHGVQRVAADAALGGLRRFPRRISDLDAGCLS
MAV_5276|M.avium_104 MKNPVGQAFSFLGLAAHLGRGAGRVSVDAVLGGRFGLPRTVDEIDPAVLS
TH_3005|M.thermoresistible__bu ------------------------MVHPALTIPPRWEDVTPEWMTAAIST
: : : . :
MMAR_0395|M.marinum_M EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR
MUL_1045|M.ulcerans_Agy99 EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR
Mvan_2228|M.vanbaalenii_PYR-1 SVIGRAVTSVSVLDGDAGTSSRARLALTGDG--VPESVFVKMAAETVGTR
Mflv_4117|M.gilvum_PYR-GCK SLMGRSVTSVAVLDGDAGTSSRARLALTGDG--VPATVFVKMAAETVATR
MSMEG_2554|M.smegmatis_MC2_155 TIMGRTVRTLSVLGGDAGTSSRARLALSGDG--VPETVFVKLPAETAATR
MAV_5276|M.avium_104 RVMGTTVRTVRVLSRDAGTSSRARLVLTGKD--VPDSVFVKVAAQTAATR
TH_3005|M.thermoresistible__bu RHPGATVERVTLLLRDDGTNRRARFELAYASGTGPRRVFVKAESGVPGRR
* * : :* . **. ***: *: . * **** : . . *
MMAR_0395|M.marinum_M FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAYDPLTGRFVLVLE
MUL_1045|M.ulcerans_Agy99 FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAFDPLTGRFVLVLE
Mvan_2228|M.vanbaalenii_PYR-1 LMGELGNLAETETRFYRELSP---ELTTGVPLSYGSAFDPYTGRYILVLE
Mflv_4117|M.gilvum_PYR-GCK LMGELGNLADTETRFYSRLSA---ELT-GVPRCHGSRFDPRTGRFVLILE
MSMEG_2554|M.smegmatis_MC2_155 LMGELGRLAHTEVRFYQQLAA---GLP-GVPRAHGSAFDALTGRFVLVLE
MAV_5276|M.avium_104 LMGELGRLGCTEVRFYRQLAP---QVV-GVPYCYGAAFDAWTGRYLLVLE
TH_3005|M.thermoresistible__bu EIHYENGNLFNESWLYRALLDGRTELPLEHPRAYAVAIDESALDYVIVFE
: . .* :* * : * .:. * : :::::*
MMAR_0395|M.marinum_M DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP
MUL_1045|M.ulcerans_Agy99 DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP
Mvan_2228|M.vanbaalenii_PYR-1 DLAG---GDCEFPDTLHPIDADRAALVVELLATVHATFWGRLPARGHAGP
Mflv_4117|M.gilvum_PYR-GCK DLADASAGPCDFPDTLHPIDADRAALVVELLARLHATFWGRLPERRGTGP
MSMEG_2554|M.smegmatis_MC2_155 DLAQ---EPCEFPDTLHPLDKDRAALTVELLARVHAAFWGRLPERSGRGP
MAV_5276|M.avium_104 DLPA---EACEFPDTLHPLSADQAGLVVELLADLHATFWNRLP-RDGRGP
TH_3005|M.thermoresistible__bu DLLER---SADPRDPTRPLTADQVADGLQGLARLHSRHWNRVGDEPELAW
** .: *. :*: *:.. :: ** :*: .* *: .
MMAR_0395|M.marinum_M FGWLYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDYVFEHYRAITG
MUL_1045|M.ulcerans_Agy99 FGWRYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITG
Mvan_2228|M.vanbaalenii_PYR-1 LGWLYSASGDSASLLTAPLLRTSARRLAERTPLPVHRGGFIDDNYRAIAS
Mflv_4117|M.gilvum_PYR-GCK LGWLYSASEDSASLLTAPLLRTSARRLAERTALPVGRGRFIDENYRAAAA
MSMEG_2554|M.smegmatis_MC2_155 LGWLYSASGDDTSLLTGTLLKTSTRRLAERADIPVADGRFIDENYRAAAQ
MAV_5276|M.avium_104 LGWLYTPSGDVTSLLTGSLMHSSIKRLAERTSIPVRDGVFIADNYRAVAA
TH_3005|M.thermoresistible__bu VQPFRPTRGWTAPMTAALPHGITAARDVLSDAVTHLDADGLVDVWTAYIG
. .. : . : * : : : *
MMAR_0395|M.marinum_M LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAVRLGHPARDLAYT
MUL_1045|M.ulcerans_Agy99 LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYT
Mvan_2228|M.vanbaalenii_PYR-1 LVDRPPHTVMHGDAHPGNLYFRDG----RAGLLDWQAVRRGHPGRELAYT
Mflv_4117|M.gilvum_PYR-GCK LIDRGPHTVMHGDAHPGNLYFRAG----QAGLLDWQAVRRGHPSRELAYT
MSMEG_2554|M.smegmatis_MC2_155 LLDRPPHTVMHGDAHPGNLFFRNG----EAGLLDWQAVRRGHPGRELAYT
MAV_5276|M.avium_104 LIDTAPHTVMHGDAHPGNMYFHGG----KAGLLDWQAVRRGHPSRELAYT
TH_3005|M.thermoresistible__bu GLGTGPQTFLHGDPHIGNTYLLPDD---TVGFLDWQVVRSGHWSHDVGYF
:. *:*.:***.* ** :: . .*:****.:* ** .:::.*
MMAR_0395|M.marinum_M LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREELWLRYRQAAAYAY
MUL_1045|M.ulcerans_Agy99 LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAY
Mvan_2228|M.vanbaalenii_PYR-1 LVTSMTTEDRRRSERDLLDVYRRALAASGGPELDGDQLWDRYRQGAMYPY
Mflv_4117|M.gilvum_PYR-GCK LTTSMTVEGRRGSQRDLLEVYRRALAAGGGPELDRDDLWDRYRQAALYPY
MSMEG_2554|M.smegmatis_MC2_155 LITSMTTTDRQAAEKDLLDEYRRALAAAGGPRLDADELWERYRLGAVYAY
MAV_5276|M.avium_104 LITSLTPEDRRATQRDLLDDYRRALAAAGGPQLDRDELWLRFRQAALYAY
TH_3005|M.thermoresistible__bu LQSALTEADRRAHEAALLAHYRNALQLPEIRRPTAEEAWLRYRASAAHGL
* :.:* .*: : ** **.** . :: * *:* .*
MMAR_0395|M.marinum_M VATTIVAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTS---
MUL_1045|M.ulcerans_Agy99 VATTIAAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAW
Mvan_2228|M.vanbaalenii_PYR-1 VATLITAGMGGMQDDGIALKGLERSLHALDDLDTVALLEKSL--------
Mflv_4117|M.gilvum_PYR-GCK VATLITVGMGGMQVEDIAMKGLERALEALDDLETVALLEKNL--------
MSMEG_2554|M.smegmatis_MC2_155 TAPVITAGLGGMQDDGIAVEGARRGVAALADLETVALLKKLL--------
MAV_5276|M.avium_104 AAPLITAGMGGMQVEDIAMEGLRRGVAALEDLETVAALKSSL--------
TH_3005|M.thermoresistible__bu PVWLITL-LSDAHPTERSRALVQRFAAAFTDLDTPAAVQTLRRT------
. *. :.. : : *: **:* * :.
MMAR_0395|M.marinum_M -----------------------------------------
MUL_1045|M.ulcerans_Agy99 RPGMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW
Mvan_2228|M.vanbaalenii_PYR-1 -----------------------------------------
Mflv_4117|M.gilvum_PYR-GCK -----------------------------------------
MSMEG_2554|M.smegmatis_MC2_155 -----------------------------------------
MAV_5276|M.avium_104 -----------------------------------------
TH_3005|M.thermoresistible__bu -----------------------------------------