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RGYFDLAGRSALVTGAAGGIGSAVAQALADAGAAVLVTDIDKDAAAVVAQRISDSGGRAEAAALDVSDRD SADAAAAQAAALTGGALHIVVNNAGVTRPAMFDKTTPESFRLLFDIHVMGAFNVTQAALPFIPIDGTGRI VNVTSAAGLTGTLGQVNYSAAKAGIIGFTKSLARELATKGITVNALAPLAATPMTETIRTNEKFAANMMN RIPMKRWAEPSEIAGAFVFMASDAASYVTGQVLPVDGGMVI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4209 | - | - | 100% (252) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_1975 | fabG | 1e-45 | 42.04% (245) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5156 | - | 2e-36 | 38.52% (244) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 9e-44 | 42.17% (249) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 9e-44 | 40.98% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1350 | fabG | 1e-43 | 42.17% (249) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-34 | 37.20% (250) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4632 | - | 2e-36 | 35.08% (248) | short chain dehydrogenase |
| M. marinum M | MMAR_4033 | fabG | 2e-43 | 40.89% (247) | 3-oxoacyl- |
| M. avium 104 | MAV_5088 | fabG | 4e-45 | 43.03% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_4835 | - | 1e-105 | 76.19% (252) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_3954 | - | 2e-44 | 43.03% (244) | PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase |
| M. ulcerans Agy99 | MUL_3898 | fabG | 1e-42 | 41.08% (241) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4209|M.vanbaalenii_PYR-1 ---MRGYFDLAG---------RSALVTGAAGGIGSAVAQALADAGAAVLV
MSMEG_4835|M.smegmatis_MC2_155 ---MRTYFDLTG---------RSALVTGAGCGIGAAVSEALAAAGAAVLV
MMAR_4033|M.marinum_M ---MSVSLLNG----------QIAVVTGGAQGLGLAIAERFVSEGARVVL
MUL_3898|M.ulcerans_Agy99 ---MCGAHRDRG--------YVYPVVTGGAQGLGLAIAERFVSEGARVVL
Mb1385|M.bovis_AF2122/97 ---MASLLNAR-----------TAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv ---MASLLNAR-----------TAVITGGAQGLGLAIGQRFVAEGARVVL
Mflv_4369|M.gilvum_PYR-GCK ----MSLLTGQ-----------TAVITGGAQGLGFAIAQRFVDEGARVVL
MAV_5088|M.avium_104 ---MAESLLLG----------KVAVVTGAGQGIGREIARALHRHGARVVL
TH_3954|M.thermoresistible__bu ---MPSALLAE----------KVAVVTGAGRGIGREIARVLHAHGAEVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_4632|M.abscessus_ATCC_1997 --MILDRFKLDG---------NVAVVTGAGRGLGAAIAEAFAQAGADVLI
::**. *:* :.. : * * :
Mvan_4209|M.vanbaalenii_PYR-1 TDIDKDAAAVVAQRISDSGGRAEAAALDVSDRDSADAAAAQAAALTGGAL
MSMEG_4835|M.smegmatis_MC2_155 TDIDGEAARTVAERINAAGGKADSAALDVGDRDAAVAAAERAAALGQGTL
MMAR_4033|M.marinum_M GDVNLEATEAAAKQLGG-GEVAVAVRCDVTKAD-EVETLLQTALERFGGL
MUL_3898|M.ulcerans_Agy99 GDVNLEATEAAAKQLGG-GEVAVAVRCDVTKAD-EVETLLQAALERFGGL
Mb1385|M.bovis_AF2122/97 GDVNLEATEVAAKRLGG-DDVALAVRCDVTQAD-DVDILIRTAVERFGGL
Rv1350|M.tuberculosis_H37Rv GDVNLEATEVAAKRLGG-DDVALAVRCDVTQAD-DVDILIRTAVERFGGL
Mflv_4369|M.gilvum_PYR-GCK GDVNLEATQEAAEKLGG-ADVAHAVRCDVTSSA-EVDALVAAAVDTFGAL
MAV_5088|M.avium_104 ADLDGSAARSAAAQIDDSGANCTGLACDVTSEE-QVGALVAGTVREHGGL
TH_3954|M.thermoresistible__bu ADLDADAAAQAAAEVDG-----TGVGCDVTAED-QMKRLVADTVAKHGRL
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDND-AIGAAFKAVEEHQGPV
MAB_4632|M.abscessus_ATCC_1997 ASRTESQLREVAAKVQAAGRQAEVVVADLSDTE-ASAALAQKAVDRFGRL
*: . * :
Mvan_4209|M.vanbaalenii_PYR-1 HIVVNNAGVTRPAMFDKTTPESFRLLFDIHVMGAFNVTQAALPFIPIDGT
MSMEG_4835|M.smegmatis_MC2_155 HILVNNAGVTAPAMFPKLTDETFRRTFDVHVMGSFHVTQSALPHLATDGT
MMAR_4033|M.marinum_M DIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKR
MUL_3898|M.ulcerans_Agy99 DIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKR
Mb1385|M.bovis_AF2122/97 DVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKR
Rv1350|M.tuberculosis_H37Rv DVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKR
Mflv_4369|M.gilvum_PYR-GCK DIMVNNAGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENKR
MAV_5088|M.avium_104 DVFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKT
TH_3954|M.thermoresistible__bu DLFVNNAGITRDASLKRMTVADFDAVVTVHLRGTWLGVREATAVMREQKS
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
MAB_4632|M.abscessus_ATCC_1997 DVVVNNVGGTMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLKSDN
.:.* *.* * : : : . .:: . : * :
Mvan_4209|M.vanbaalenii_PYR-1 GRIVNVTSAAGLTGTLGQVNYSAAKAGIIGFTKSLARELATKGITVNALA
MSMEG_4835|M.smegmatis_MC2_155 GRIINVTSSAGITGTLGQVNYSAAKAGLIGFTKSLARELAPRNIMVNALA
MMAR_4033|M.marinum_M GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAIA
MUL_3898|M.ulcerans_Agy99 GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAIA
Mb1385|M.bovis_AF2122/97 GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIA
Rv1350|M.tuberculosis_H37Rv GAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIA
Mflv_4369|M.gilvum_PYR-GCK GVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQ
MAV_5088|M.avium_104 GSIVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQ
TH_3954|M.thermoresistible__bu GSIVNISSLSGKSGNPGQTNYSAAKAGIIGLTKAAAKEVAHHNVRVNAIQ
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
MAB_4632|M.abscessus_ATCC_1997 ASVINITSTMGRLPGRAFLGYCTAKGALAHYTRTAAMDLSPR-IRVNGIA
. : : * * . .*.::*..: ::: : ::. : .* :
Mvan_4209|M.vanbaalenii_PYR-1 P-LAATPMTETIRTNEKFAANMMNRIPMKRWAEPSEIAGAFVFMASDAAS
MSMEG_4835|M.smegmatis_MC2_155 P-LAATPMTETIRTNEKFAANMMNRILLKRWADAEEVAGAFVFLASDAAS
MMAR_4033|M.marinum_M PGLIRSAMTEAMPQ--RIWDQKLAEVPMGRAGEPSEVASVALFLACDLSS
MUL_3898|M.ulcerans_Agy99 PGLIRSAMTEAMPQ--RIWDQKLAEVPMGRAGEPSEVASVALFLACDLSS
Mb1385|M.bovis_AF2122/97 PGLIRSAMTEAMPQ--RIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSS
Rv1350|M.tuberculosis_H37Rv PGLIRSAMTEAMPQ--RIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSS
Mflv_4369|M.gilvum_PYR-GCK PGLIRSAMTEAMPQ--RIWDSKVAEVPLGRAGEPDEVAKVALFLASDLSS
MAV_5088|M.avium_104 PGLIRTPMTAAMPP--DVFAEREAAVPMKRAGEPEEVAGAVVFLASELSS
TH_3954|M.thermoresistible__bu PGLIRTPMTETMPA--EVFAEREAAVPMKRAGEPAEVAGAVVFLGSDLSS
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAG
MAB_4632|M.abscessus_ATCC_1997 PGSILTSALEVVAGNDEMRNTLEQNTPLHRLGDPADIAAAAVYLASPAGS
* : .: : * . ::* . ::.. ..
Mvan_4209|M.vanbaalenii_PYR-1 YVTGQVLPVDGGMVI-----------
MSMEG_4835|M.smegmatis_MC2_155 YITGQVLPVDGGMVM-----------
MMAR_4033|M.marinum_M YMTGTVLDVTGGRFI-----------
MUL_3898|M.ulcerans_Agy99 YMTGTVLDVTGGRFI-----------
Mb1385|M.bovis_AF2122/97 YMTGTVLDVTGGRFI-----------
Rv1350|M.tuberculosis_H37Rv YMTGTVLDVTGGRFI-----------
Mflv_4369|M.gilvum_PYR-GCK YMTGTVLEVTGGRHL-----------
MAV_5088|M.avium_104 YITGTVLGVGGGRYM-----------
TH_3954|M.thermoresistible__bu YITGSVIEVGGGRYM-----------
MLBr_01807|M.leprae_Br4923 YISGAVIPVDGGLGMGH---------
MAB_4632|M.abscessus_ATCC_1997 FLTGKVLEVDGGLIAPNLDIPLPDLA
:::* *: * **