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SPLPTEEWDDEVLDALAPLLPPSRSNPRDAGNVLATLVRHPALTRAYLHFNAHLLLASTLSPRIREVALL RAVHVRRSDYLWEHHIPIAQRAGITPDEIDAIRQGRPADEIDRLVVGAVDELDAANTVSDATWSALRDHF DERQVLDLIFTVGCYQLLGAAVNTLGVQPEPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4181 | - | - | 100% (173) | carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_4212 | - | 8e-46 | 46.78% (171) | carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_4316 | - | 1e-24 | 35.36% (181) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 3e-11 | 24.31% (144) | hypothetical protein Mb1558 |
| M. gilvum PYR-GCK | Mflv_2473 | - | 6e-70 | 71.68% (173) | carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv1531 | - | 3e-11 | 24.31% (144) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 1e-07 | 23.85% (130) | hypothetical protein MLBr_02465 |
| M. abscessus ATCC 19977 | MAB_4119 | - | 5e-14 | 33.06% (124) | hypothetical protein MAB_4119 |
| M. marinum M | MMAR_4743 | - | 1e-51 | 53.22% (171) | hypothetical protein MMAR_4743 |
| M. avium 104 | MAV_3958 | pcaC | 2e-54 | 60.82% (171) | hypothetical protein MAV_3958 |
| M. smegmatis MC2 155 | MSMEG_4839 | - | 4e-49 | 52.05% (171) | carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_3878 | - | 2e-63 | 69.01% (171) | PUTATIVE Carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 1e-08 | 29.06% (117) | hypothetical protein MUL_4533 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 -----MTTSRVPLLPVDEAKAAADEAGVPDYMAELS-------IFQVLLN
Rv1531|M.tuberculosis_H37Rv -----MTTSRVPLLPVDEAKAAADEAGVPDYMAELS-------IFQVLLN
Mvan_4181|M.vanbaalenii_PYR-1 ----------MSPLPTEEWDDEVLDALAPLLPPSRSNPRDAGNVLATLVR
Mflv_2473|M.gilvum_PYR-GCK -----MSTPRLEPLPADRWDDAARDAVSPLLSEERRNPRGAGNVVGTLAR
TH_3878|M.thermoresistible__bu -------VTRLSPLPAEEWTDEVRRSLAPLLAPDRANPRDAGNVLATLVR
MAV_3958|M.avium_104 MAASDRHPQRLTPLPADEWDEDTRAALASLIPAERANPVGAGNVLSTLVR
MMAR_4743|M.marinum_M --------MRLPPLPADQWDEAVQRSLSVILPAQRCNPRDAGNALSTFAN
MSMEG_4839|M.smegmatis_MC2_155 --------MRLTPLPADEWDDEVRLALSVMLPEERLNPEGAGTALSTLAR
MLBr_02465|M.leprae_Br4923 -MSGGTGTGPVGRIPPGSLRQLGPINWVIAKLAASLLRTSEMHLFTILGQ
MUL_4533|M.ulcerans_Agy99 -MTG----DQVARIPSGGIRQLGPVNWALAKLAARSVRAPEMHLFTALGY
MAB_4119|M.abscessus_ATCC_1997 -MSS-------GRIPSGGLRELGPINWVIAKGMARAVNAPEMHLATTLGQ
:* :
Mb1558|M.bovis_AF2122/97 HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Rv1531|M.tuberculosis_H37Rv HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVA
Mvan_4181|M.vanbaalenii_PYR-1 HPALTRAYLHFNAHLLLASTLSPRIREVALLRAVHVRRSDYLWEHHIPIA
Mflv_2473|M.gilvum_PYR-GCK HPGLTRAYLTFNAHLLLASTLTPRIREVALLRAVHVRPCDYLWDHHLPIA
TH_3878|M.thermoresistible__bu HPALTRAYLEFNAYLLRDSTLSTRTREVAVLRVVLLRDCEYLWEHHIPLA
MAV_3958|M.avium_104 HPDLTAAYLPFNAYLLTRSTLSPRIREVALLRVVHRSKCGYLWSHHLPIA
MMAR_4743|M.marinum_M HPALAKAFLRFNTHLLFASTLPARVRELAILRVAHRRACAYEWTHHVALA
MSMEG_4839|M.smegmatis_MC2_155 HPRLTKAFLRFSNHLLFRSTLDPRLRELAILRIARRRNCEYEWAHHAFIG
MLBr_02465|M.leprae_Br4923 RQLLFWAWLIYGGRLLRG-KLPRVDTELVILRVAHLRTCEYELQHHRRMA
MUL_4533|M.ulcerans_Agy99 RQYLFWTWAIYSGRLLHG-RLPRIDTELVILRVAHLRSCEYELQHHRRMA
MAB_4119|M.abscessus_ATCC_1997 TGARFWPWLAYSGAILRGTKLSTRDTEVVILRVAHVRECEYELQHHTRIA
.: :* * *:.::* . * :* :.
Mb1558|M.bovis_AF2122/97 SGLGVSADDLLGVRDW---QGYNG----FGPAEQAVLAATDDVVREGAVS
Rv1531|M.tuberculosis_H37Rv SGLGVSADDLLGVRDW---QGYNG----FGPAEQAVLAATDDVVREGAVS
Mvan_4181|M.vanbaalenii_PYR-1 QRAGITPDEIDAIRQG---RPAD-------EIDRLVVGAVDELDAANTVS
Mflv_2473|M.gilvum_PYR-GCK HGTGLTDAEIASIRSG---DPDD-------AVDRLVVHAVDELHGSNTLS
TH_3878|M.thermoresistible__bu QRAGLTPAEIVGIRNG---RMAD-------EPDQLVVRAADELARDHEIS
MAV_3958|M.avium_104 RRAGLSESDIDDIRRG---RCAD-------PTDAAVVRAVDELTGESTLS
MMAR_4743|M.marinum_M EQAGISGDEIAAVRRG---EATD-------DFERAVLTGVDELDENSELS
MSMEG_4839|M.smegmatis_MC2_155 KAEGLTDDDIDGIGRG---VVSD-------PFDQVVIDAVDELDELSTIS
MLBr_02465|M.leprae_Br4923 RKRGLDTKIQAMIFAWPDVPTGAG----LSVRQQALLAATDEFVKDRKIT
MUL_4533|M.ulcerans_Agy99 RAAGLDAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDELIKNRSVT
MAB_4119|M.abscessus_ATCC_1997 KSAGIDPAYQERIFTG---AGAEG----LSDKERALITGVDEILTTRTLS
*: : : :: ..*:. ::
Mb1558|M.bovis_AF2122/97 AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Rv1531|M.tuberculosis_H37Rv AQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWP
Mvan_4181|M.vanbaalenii_PYR-1 DATWSALR--DHFDERQVLDLIFTVGCYQLLGAAVNTLGVQPEPH-----
Mflv_2473|M.gilvum_PYR-GCK DDTWTALS--DHFDERQVLDLIFTVGCYQMLGAAVNALGIQPETH-----
TH_3878|M.thermoresistible__bu EGTWRALG--RHFDDRGRMDLVFTVGCYALLAVAVNTFGVEPEHA-----
MAV_3958|M.avium_104 RQTWDRLC--ELFTQRQCMDLIFTIGGYLLLALAVNTFGVQEEEETR---
MMAR_4743|M.marinum_M DQTWAALG--EHLDDRQRMDYVFTVGCYALLAMAFNTFGVQLEELEQDRA
MSMEG_4839|M.smegmatis_MC2_155 DPTWAALG--EKLDDRQRMDLVFTVGGYGLMAMAYNTFGIEPESGH----
MLBr_02465|M.leprae_Br4923 SSSWQQLE--THLDRRRLIEFCMLISQYDGLAATISSLDIPLDNSC----
MUL_4533|M.ulcerans_Agy99 PATWEQLE--IHLNRRRLIEFCLLATQYDALAATITALGVPLDNPR----
MAB_4119|M.abscessus_ATCC_1997 DEAWEGLS--KFLDRRQLIGFCLLVTQYDGLAATMSSLRIPLDH------
:* : : :. :: : :
Mb1558|M.bovis_AF2122/97 PDGLSPR
Rv1531|M.tuberculosis_H37Rv PDGLSPR
Mvan_4181|M.vanbaalenii_PYR-1 -------
Mflv_2473|M.gilvum_PYR-GCK -------
TH_3878|M.thermoresistible__bu -------
MAV_3958|M.avium_104 -------
MMAR_4743|M.marinum_M ER-----
MSMEG_4839|M.smegmatis_MC2_155 -------
MLBr_02465|M.leprae_Br4923 -------
MUL_4533|M.ulcerans_Agy99 -------
MAB_4119|M.abscessus_ATCC_1997 -------