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M. vanbaalenii PYR-1 Mvan_4164 (-)

annotation: amidohydrolase 2
coordinates: 4475313 - 4476446
length: 377

VKVLSDGSAGALEAQVKVPVIDASVHIFCQSNKDLRRNFLQEPFRSRGFPDYEMDWYGAPGGEYAERTTG
PDDQYPGSDPEVVAKHLFTDRGVDIAVLHPMTRGIMPDRHLGTALAAAHNEMMVTRWLDHPQLGEKFRGT
LRVNPDDIAGALREIDKYKSHPRIVQLGIPLQSRELYGKPQYWPLWEAAVDAGWPVAVHFEVGSGVQLPP
TPSGLTRTYEQFVGFTALNFLYHLMNMIAEGVFERMPALKFVWADGAADMLTPFIWRMDCFGRPHLEQTP
WAPRIPSDYLPDHVYFVQGALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQLNELSVPTAYTPDQRDK
LCWRNAAALYGIESPVIPAVSTTAAAQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4164--100% (377)amidohydrolase 2
M. vanbaalenii PYR-1Mvan_4165-4e-3629.03% (372) amidohydrolase 2
M. vanbaalenii PYR-1Mvan_0901-8e-0923.18% (358) amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2490-0.087.00% (377) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4724-1e-16876.07% (351) metal-dependent hydrolase
M. avium 104MAV_0930-1e-17077.25% (356) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_4807-0.081.82% (352) amidohydrolase family protein
M. thermoresistible (build 8)TH_4618-0.080.43% (368) PUTATIVE amidohydrolase 2
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_4164|M.vanbaalenii_PYR-1       -MKVLSDGSAGALEAQVKVPVIDASVHIFCQSNKDLRRNFLQEPFRSRGF
Mflv_2490|M.gilvum_PYR-GCK          -MKEFSDGSSG----VARVPVIDASVHIFCQSNKDLRKNFLREPFRSRGF
MSMEG_4807|M.smegmatis_MC2_155      -------------------------MHIFFGSNKDLRQNFLREPFASRGF
TH_4618|M.thermoresistible__bu      -VIELSDG--------TRTPVIDASVHIFCKSNKDLRGTFLREPFKSRGF
MMAR_4724|M.marinum_M               MVIEHADG--------TRMPVIDASVHIFFPSNKDLR-SFLREPFKSRGF
MAV_0930|M.avium_104                -MIEHADG--------TRTPVIDASVHIFFPSNKDLR-SFLREPFKSRGF
                                                             :***  ****** .**:*** ****

Mvan_4164|M.vanbaalenii_PYR-1       PDYEMDWYGAPGGEYAERTTGPDDQYPGSDPEVVAKHLFTDRGVDIAVLH
Mflv_2490|M.gilvum_PYR-GCK          PDYEMDWYGAPGGEYAPRTEGPDGQYPGSDPELVAKHLFTDRGVDLAILH
MSMEG_4807|M.smegmatis_MC2_155      PDYEMNWYGAPGGEYAKNTKGPDRQYPGSDPDVAAQHLFTERGVDIAILH
TH_4618|M.thermoresistible__bu      PDYEMDWYGAPGGEYAKGTEGPDRQYPGSDPDVVAQHLFEQRGVDIAVLH
MMAR_4724|M.marinum_M               PDYEMDWYGAPGSEYAPNTEGPDRQYPGSDPKFVADELFSRRGVDVAVLH
MAV_0930|M.avium_104                PDYEMDWYGAPGSEYAPNTDGPDGQYPGSDPEFVAQELFSKRGVDVAVLH
                                    *****:******.***  * *** *******...*..**  ****:*:**

Mvan_4164|M.vanbaalenii_PYR-1       PMTRGIMPDRHLGTALAAAHNEMMVTRWLDHPQLGEKFRGTLRVNPDDIA
Mflv_2490|M.gilvum_PYR-GCK          PMTRGIMPDRHLGTAIASAHNEMMVTRWLDHPEFGERFRGTLRVNPDDIA
MSMEG_4807|M.smegmatis_MC2_155      PMTRGIMPDRHLGTALANAHNEMMVTRWLDHERYGERFRGTIRVNPDDIA
TH_4618|M.thermoresistible__bu      PMTRGIMPDRHLGTALAAAHNEMLVTRWLDHPEFGDRFRGTIRVNPDDIA
MMAR_4724|M.marinum_M               PMGRGIMPDRHLGSALHAAHNEMMVSRWLEHDEFGDRFRGTIRVNPDDIA
MAV_0930|M.avium_104                PMGRGIMPDRHLGSALHAAHNEMMVSRWLDSPEFGEKFRGTIRVNPDDIA
                                    ** **********:*:  *****:*:***:  . *::****:********

Mvan_4164|M.vanbaalenii_PYR-1       GALREIDKYKSHPRIVQLGIPLQSRELYGKPQYWPLWEAAVDAGWPVAVH
Mflv_2490|M.gilvum_PYR-GCK          GALREIDKYRDHPRIVQLGIPLQSREVYGKPQFWPLWEAAVDAGWPVAVH
MSMEG_4807|M.smegmatis_MC2_155      GALREIERFKDHPRVVQIGVPLQSRELYGKPQYWPLWEAASDAGLPVAVH
TH_4618|M.thermoresistible__bu      GSLREIEKYKDHPRVVQLGIPLQSRELYGKPQFWPLWEAAVAANLPVAVH
MMAR_4724|M.marinum_M               GAVREVAKWRAHPRVVQIGVPLQSRELYGKPQFWPLWEAAVEAGLPVAVH
MAV_0930|M.avium_104                GALRELERWRSHPRVVQLGIPLQSRELYGKPQFWPLWEAAADANLPVAVH
                                    *::**: ::: ***:**:*:******:*****:*******  *. *****

Mvan_4164|M.vanbaalenii_PYR-1       FEVGSGVQLPPTPSGLTRTYEQFVGFTALNFLYHLMNMIAEGVFERMPAL
Mflv_2490|M.gilvum_PYR-GCK          FEVGSGVALPPTPNGLTRTYEQYVGFTALNFLYHLMNMIAEGVFERMPDL
MSMEG_4807|M.smegmatis_MC2_155      IEVGAGVQFAPTPSGKTRTYEQYLGFMALNYLYHLMNMIAEGVFERMPAL
TH_4618|M.thermoresistible__bu      IEVGAGIAASPTPSGNTRTYEQYVGFMALNYLYHLMNMIAEGVFERMPTL
MMAR_4724|M.marinum_M               IESGEGIGFPPTPSGHTRTYEQYVSFMALNYLYHLMNMIAEGVFERFAEL
MAV_0930|M.avium_104                IETGEGIGFPPTPSGHTQTYEQYVSFMALNYLYHLMNMIAEGVFERFPAL
                                    :* * *:  .***.* *:****::.* ***:***************:. *

Mvan_4164|M.vanbaalenii_PYR-1       KFVWADGAADMLTPFIWRMDCFGRPHLEQTPWAPRIPSDYLPDHVYFVQG
Mflv_2490|M.gilvum_PYR-GCK          KFVWADGAADLLTPFMWRMDCFGRPHLEQTPWAPRMPSDYLPGHVFFVQG
MSMEG_4807|M.smegmatis_MC2_155      KFVWADGAADLLTPFIWRMDCFGRPHLEQTPWAPKMPSDYLPGHVYFVQG
TH_4618|M.thermoresistible__bu      KFVWADGAADLLTPFIWRMDCFGRPHLEQTPWAPRMPSDYLPGHVYFVQG
MMAR_4724|M.marinum_M               KFIWADGAADFVTPFIWRMDTFGRPHLEQTPWAPRIPSDYLPGHVYFIQG
MAV_0930|M.avium_104                KFVWADGAADFLTPFIWRMDTFGRPHLEQTPWAPRIPSDYIPGHVYFVQG
                                    **:*******::***:**** *************::****:*.**:*:**

Mvan_4164|M.vanbaalenii_PYR-1       ALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQL----NELSVPTAYTP
Mflv_2490|M.gilvum_PYR-GCK          ALDGPGDVDFAGEWAGFTGKDDMVMYGSSYPHWQL----NELTVPGSYDP
MSMEG_4807|M.smegmatis_MC2_155      ALDGPGDVEFAGEWFGFTGKENMVMFGSSYPHWQL----NEPEVPTAFTP
TH_4618|M.thermoresistible__bu      FLDGPGDVDFAGEWFGFTGKENMVMFGSSYPHWQL----NELTIPGTFSA
MMAR_4724|M.marinum_M               GLDGPGDVEFADEWLSFTGKEDMVMFGSSYPHWQCYDLRDVRNLPTALTA
MAV_0930|M.avium_104                SLDGPGDADFAAEWFGFTGKEDMVMFGSSYPHWQC---ADVHKLPPALSA
                                     ******.:** ** .****::***:********     :   :* :  .

Mvan_4164|M.vanbaalenii_PYR-1       DQRDKLCWRNAAALYGIESPVIPAVSTTAAAQ
Mflv_2490|M.gilvum_PYR-GCK          EQRDKLCWRNAAQLYGIQS---PAISVPAAAQ
MSMEG_4807|M.smegmatis_MC2_155      EQRDKLLWRNAAELYGLQS---ALTSTAGAAR
TH_4618|M.thermoresistible__bu      EQRDKLCWRNAAELYNIES---SAIPSAALAK
MMAR_4724|M.marinum_M               DQREKLCWRNAAELYGIDI------SAELTSG
MAV_0930|M.avium_104                EQREKLCWRTAADLYGIDI------SVDLAAS
                                    :**:** **.** **.::       .    :