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MIALTIGLAVFVGIALGLLGGGGSILTVPLLAYVAGMDAKAAIATSLLVVGVTSAIGAISHARAGRVQWR TGLIFGAAGMAGAYAGGLLARYIPGTILLIGFALMMIATAIAMLRGRKTIETGETGHRLPVPKILAEGLI VGLVTGLVGAGGGFLVVPALALLGGLPMPIAVGTSLIVIAMKSFAGLAGYLTSVHINWTLALAVTAAAVI GALIGARLTAMINPDSLRKTFGWFVLVMSSVILAQEIHPAVGITAAALTTLAAATTLACQRYAHCPLSRL TTRLTTPKAAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4025 | - | - | 100% (291) | hypothetical protein Mvan_4025 |
| M. vanbaalenii PYR-1 | Mvan_1828 | - | e-157 | 98.63% (291) | hypothetical protein Mvan_1828 |
| M. vanbaalenii PYR-1 | Mvan_5834 | - | 8e-51 | 39.29% (252) | hypothetical protein Mvan_5834 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2902c | - | 2e-06 | 28.64% (213) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0983 | - | 1e-136 | 86.48% (281) | hypothetical protein Mflv_0983 |
| M. tuberculosis H37Rv | Rv2877c | - | 2e-06 | 28.64% (213) | integral membrane protein |
| M. leprae Br4923 | MLBr_00468 | - | 3e-11 | 23.46% (243) | hypothetical protein MLBr_00468 |
| M. abscessus ATCC 19977 | MAB_1170 | - | 2e-22 | 32.58% (264) | hypothetical protein MAB_1170 |
| M. marinum M | MMAR_2104 | speE | 9e-05 | 23.87% (222) | spermidine synthase, SpeE |
| M. avium 104 | MAV_3519 | - | 2e-08 | 26.23% (244) | hypothetical protein MAV_3519 |
| M. smegmatis MC2 155 | MSMEG_5387 | - | 1e-111 | 71.03% (290) | hypothetical protein MSMEG_5387 |
| M. thermoresistible (build 8) | TH_4293 | - | 1e-125 | 76.79% (293) | PUTATIVE putative protein of unknown function DUF81 |
| M. ulcerans Agy99 | MUL_1708 | speE | 5e-05 | 23.87% (222) | spermidine synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4025|M.vanbaalenii_PYR-1 -------MIALTIGLAVFVG-------IALGLLGGGGSILTVPLLAYVAG
Mflv_0983|M.gilvum_PYR-GCK -------MMALTVGLAVFVG-------IALGLLGGGGSILTVPLLAYVAG
TH_4293|M.thermoresistible__bu -------MIGLIIALAVLVG-------VALGLLGGGGSILMVPLLAYVAG
MSMEG_5387|M.smegmatis_MC2_155 -------MIALTIVLAVFVG-------IALGMLGGGGSILTVPLLAYVAG
MLBr_00468|M.leprae_Br4923 ----MLVSHLATIGLAGFGA-------GAINALVGSGTLITFPTLVALGY
MAV_3519|M.avium_104 ---------MFVICLAGLAA-------GAINALVGSGTLITFPTLVALGY
Mb2902c|M.bovis_AF2122/97 -------MNEALIGLAFAAG--------LVAALNPCGFAMLPAYLLLVVH
Rv2877c|M.tuberculosis_H37Rv -------MNEALIGLAFAAG--------LVAALNPCGFAMLPAYLLLVVY
MMAR_2104|M.marinum_M MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIYELALLTLSTS
MUL_1708|M.ulcerans_Agy99 MTATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTS
MAB_1170|M.abscessus_ATCC_1997 --MTERPGVGTLARIGVLGG-------MSGGLLGGGTGVITVPSLARATT
. . *
Mvan_4025|M.vanbaalenii_PYR-1 --MDAKAAIATSLLVVGVTSAIG--AISHAR----AGRVQWRTGLIFGAA
Mflv_0983|M.gilvum_PYR-GCK --MDAKQAIATSLLVVGVTSAIG--AVSHAR----AGRVQWRTGLIFGAA
TH_4293|M.thermoresistible__bu --MDAKAAIATSLLVVGVTSAVG--AVSHAR----AGQVRWRTGLIFGAA
MSMEG_5387|M.smegmatis_MC2_155 --MDAKQAVTTSLLVVGVTSAVS--AVSHAR----AGRVQWRAGLSFGAA
MLBr_00468|M.leprae_Br4923 SPVTSTMSNAVGLVAGGVSATWGYRAELGDR----WSRLRWQIPMSLTGA
MAV_3519|M.avium_104 PPVTATMSNATGLVAGSVSGTWGYRAELRGQ----WDRLRWQLPASLAGA
Mb2902c|M.bovis_AF2122/97 --GQDSAGRTGPLSAVGRAAAATVGMALG-------------FLTVFGIF
Rv2877c|M.tuberculosis_H37Rv --GQDSAGRTGPLSAVGRAAAATVGMALG-------------FLTVFGIF
MMAR_2104|M.marinum_M --LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGII
MUL_1708|M.ulcerans_Agy99 --LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGMI
MAB_1170|M.abscessus_ATCC_1997 ---LSRAVIHGTATLPNVSAAIAGSTVYALHG----AKVDVVAGAGLMAG
. .: :
Mvan_4025|M.vanbaalenii_PYR-1 GMAG----AYAGGLLARYIPGTILLIGFALMMIATAIAMLRGRKTIETGE
Mflv_0983|M.gilvum_PYR-GCK GMAG----AYAGGLLARFIPGTVLLIGFALMMIATAVAMLRGRKNVQATE
TH_4293|M.thermoresistible__bu GMAG----AYAGGILARFIPGTVLLLGFAVMMAATAVAMLRGRRNTATPD
MSMEG_5387|M.smegmatis_MC2_155 GMAG----AYAGGVLGRFIPGTALLIAFAVVMVAAAIPMLRGRR---APE
MLBr_00468|M.leprae_Br4923 ALGAFLLLHLPEKVFTAIVP-MLLVLALVLVVAGPRIQSWTRCRAKAAVN
MAV_3519|M.avium_104 GLGAYLLLHLPEKVFAEIVP-VLLVAALVLVVTGPRIQAWTARRAELAGR
Mb2902c|M.bovis_AF2122/97 GALT----ISAATAVQRYLPYATVLIGLALIALGGWLLLGRGLTALTPRS
Rv2877c|M.tuberculosis_H37Rv GALT----ISAATAVQRYLPYATVLIGLALIALGGWLLLGRGLTALTPRS
MMAR_2104|M.marinum_M GGLS----AAALYVAFAFIDGSTWVLALGTALIGG--LVGAEVPLLMTLL
MUL_1708|M.ulcerans_Agy99 GGLS----AAALYVAFAFIDGSTWVLALGTALIGG--LVGAEVPLLMTLL
MAB_1170|M.abscessus_ATCC_1997 GVIG----AVVGAKLVARIPEWILKALFVFVLLATAAKLLLSAAGIDPSA
. : : . .
Mvan_4025|M.vanbaalenii_PYR-1 TG--HRLPVPKIL--AEG--LIVGLVTGLVGAGGG----FLVVPALALLG
Mflv_0983|M.gilvum_PYR-GCK GS--HRLPVPKIL--AEG--LLVGLVTGLVGAGGG----FLVVPALALLG
TH_4293|M.thermoresistible__bu TGGDHRLPVPRIL--ADG--LVVGLVTGLVGAGGG----FLVVPALALLG
MSMEG_5387|M.smegmatis_MC2_155 ATTAHGLPVVRVV--SLG--LAVGGLTGMIGAGGG----FLVVPALTLLG
MLBr_00468|M.leprae_Br4923 RAEHTTPAQMAML--ALGT-FAVSVYGGYFTAGQG----ILLVSLMSILL
MAV_3519|M.avium_104 SPEHVPPGRMATL--VFGT-FAVGVYGGYFTAAQG----ILLVGLMGALL
Mb2902c|M.bovis_AF2122/97 LGVRWAPTVRLGS--MYG--YGISYAVASLSCTIGP---FLAVTGAGLRG
Rv2877c|M.tuberculosis_H37Rv LGVRWAPTVRLGS--MYG--YGISYAVASLSCTIGP---FLAVTGAGLRG
MMAR_2104|M.marinum_M QRGRLAEAADTGR--TLANLNAADYLGALIGGLVWP---FVLLPHLGMIR
MUL_1708|M.ulcerans_Agy99 QRGRLAEAADTGR--TLANLNAADYLGALIGGLVWP---FVLLPHLGMIR
MAB_1170|M.abscessus_ATCC_1997 GEALLPEGVLAHVPSVIAIGAVVGFVVGAWSAALGLGGGLLTVPAMLVLF
. . . :: :
Mvan_4025|M.vanbaalenii_PYR-1 GLPMP--------IAVGTSLIVIAMKSFAGLAGYL---TSVH-INWTLAL
Mflv_0983|M.gilvum_PYR-GCK GLPMP--------VAVGTSLIVIAMKSFAGLGGYL---SSVQ-IDWSLAL
TH_4293|M.thermoresistible__bu GLSMP--------AAVGTSLVVIAMKSFAGLAGYL---TSVQ-IDWPVAL
MSMEG_5387|M.smegmatis_MC2_155 GLPMP--------AAVGTSLIVIALNSFSGLAGHL---TGLQ-IDWALAA
MLBr_00468|M.leprae_Br4923 PESMQR-------INAAKNLLSMLVNLTAAVGYTL---VAFDRINWSAAG
MAV_3519|M.avium_104 PESVQR-------MNAAKNLLALVVNVVAAVAYTS---VAFGRISWAAAG
Mb2902c|M.bovis_AF2122/97 GSVVG---------SVAIYLA------------------YVAGLTLVVGV
Rv2877c|M.tuberculosis_H37Rv GSVVG---------SVAIYLA------------------YVAGLTLVVGV
MMAR_2104|M.marinum_M GAAATGIVNLVAAAVVSIFLLRQVVSTRQLAMALS---SLLAALGLLVTL
MUL_1708|M.ulcerans_Agy99 GAAATGIVNLVAAAVVSIFLLRQVVSTRQLAMALC---SLLAALGLLVTL
MAB_1170|M.abscessus_ATCC_1997 GSELH--------VAEGTSLMVMLPNALVAATTHLRQGTADAPIGFRLAA
. * :
Mvan_4025|M.vanbaalenii_PYR-1 AVTAAAVIGALIGARLTAMINPDSLRKTFGWFVLVM--------------
Mflv_0983|M.gilvum_PYR-GCK AVTAAAVVGALLGARLTSMVNPDSLRKAFGWFVLAM--------------
TH_4293|M.thermoresistible__bu AVTVAAVAGALLGSRLTALVNPDTLRQAFGWFVLTM--------------
MSMEG_5387|M.smegmatis_MC2_155 AVTGAAVAGCLIGTRLITKINADALRKAFGWFVLAM--------------
MLBr_00468|M.leprae_Br4923 MIAASSLVGGLVGTRYARRLSPNVLRATIVAIGLIG--------------
MAV_3519|M.avium_104 LIAAGSLVGGLLGARYGRRLSGGALRAIIVVVGLIG--------------
Mb2902c|M.bovis_AF2122/97 LAVAAATASSALADRLRRILPFVNRISGALLVVVG------LYVG-----
Rv2877c|M.tuberculosis_H37Rv LAVAAATASSALADRLRRILPFVNRISGALLVVVG------LYVG-----
MMAR_2104|M.marinum_M LVHARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQF
MUL_1708|M.ulcerans_Agy99 LVHARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQF
MAB_1170|M.abscessus_ATCC_1997 FALPGTVIGALLALALNARWLALVFGSYLVFIAVREIVR-----------
.
Mvan_4025|M.vanbaalenii_PYR-1 ----SSVILAQEIHPAVGITAAALTTLAAA--------------------
Mflv_0983|M.gilvum_PYR-GCK ----SSVILAQEIHLAVGIAGAALTAIAAL--------------------
TH_4293|M.thermoresistible__bu ----SAVILAQEAHPAVGAAAAVLTAVAAA--------------------
MSMEG_5387|M.smegmatis_MC2_155 ----SSVILAQEIHPFVGLAAASLTVIAAS--------------------
MLBr_00468|M.leprae_Br4923 ----LVRLLAV---------------------------------------
MAV_3519|M.avium_104 ----LYRLLAVA--------------------------------------
Mb2902c|M.bovis_AF2122/97 ----YYGLYELRLIAGVGANPQDAVIAAAG--------------------
Rv2877c|M.tuberculosis_H37Rv ----YYGLYELRLIAGVGANPQDAVIAAAG--------------------
MMAR_2104|M.marinum_M STRDEYRYTESLVYPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQV
MUL_1708|M.ulcerans_Agy99 STRDEYRYTESLVYPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQV
MAB_1170|M.abscessus_ATCC_1997 -----AIRTAAAKTKKSGPAPVPQVCVGG---------------------
Mvan_4025|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0983|M.gilvum_PYR-GCK --------------------------------------------------
TH_4293|M.thermoresistible__bu --------------------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 ------------------------------------RLQGALAG------
Rv2877c|M.tuberculosis_H37Rv ------------------------------------RLQGALAG------
MMAR_2104|M.marinum_M ELDPAVIELARTTMREANGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFD
MUL_1708|M.ulcerans_Agy99 ELDPAVIELARTTMREANGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFD
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4025|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0983|M.gilvum_PYR-GCK --------------------------------------------------
TH_4293|M.thermoresistible__bu --------------------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 -----------------------------------WVNQHG---------
Rv2877c|M.tuberculosis_H37Rv -----------------------------------WVNQHG---------
MMAR_2104|M.marinum_M AVIVDLPDPDTPALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAF
MUL_1708|M.ulcerans_Agy99 AVIVDLPDPDTPALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAF
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4025|M.vanbaalenii_PYR-1 ----TTLACQRYAHCPLSRLTTRLTTPKAAA-------------------
Mflv_0983|M.gilvum_PYR-GCK ----MTFACSRYAHCPLRRITGIGAARGAHA-------------------
TH_4293|M.thermoresistible__bu ----LTFTCSRYGRCPLRRVAEALSSRPATA-------------------
MSMEG_5387|M.smegmatis_MC2_155 ----MTMVCARFSRCPLRRVTRLSMARPAVA-------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 --------AWPWAVLLVVLVVGAFAGTWFRRVRR----------------
Rv2877c|M.tuberculosis_H37Rv --------AWPWAVLLVVLVVGAFAGTWFRRVRR----------------
MMAR_2104|M.marinum_M WRTVSTIKAAGYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSL
MUL_1708|M.ulcerans_Agy99 WRTVSTIKAAGYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSL
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_4025|M.vanbaalenii_PYR-1 --------------------------------------------
Mflv_0983|M.gilvum_PYR-GCK --------------------------------------------
TH_4293|M.thermoresistible__bu --------------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 --------------------------------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------
Mb2902c|M.bovis_AF2122/97 --------------------------------------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------------------
MMAR_2104|M.marinum_M RFLNQPVLNAATVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR--
MUL_1708|M.ulcerans_Agy99 RFLNQPVLNAATVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------