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IALTIGLAVFVGIALGLLGGGGSILTVPLLAYVAGMDAKAAIATSLLVVGVTSAIGAISHARAGRVQWRT GLIFGAAGMAGAYAGGLLARYIPGTILLIGFAVMMIATAIAMLRGRKTIETGETGHRLPVPKIVAEGLIV GLVTGLVGAGGGFLVVPALALLGGLPMPIAVGTSLIVIAMKSFAGLAGYLTSVHINWTLALAVTAAAVIG ALIGARLTAMINPDSLRKTFGWFVLVMSSVILAQEIHPAVGITAAALTLIAAATTLACQRYAHCPLSRLT TRLTTPKAAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1828 | - | - | 100% (291) | hypothetical protein Mvan_1828 |
| M. vanbaalenii PYR-1 | Mvan_4025 | - | e-157 | 98.63% (291) | hypothetical protein Mvan_4025 |
| M. vanbaalenii PYR-1 | Mvan_5834 | - | 3e-51 | 39.68% (252) | hypothetical protein Mvan_5834 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2902c | - | 7e-06 | 27.96% (211) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0983 | - | 1e-135 | 86.12% (281) | hypothetical protein Mflv_0983 |
| M. tuberculosis H37Rv | Rv2877c | - | 7e-06 | 27.96% (211) | integral membrane protein |
| M. leprae Br4923 | MLBr_00468 | - | 1e-10 | 23.05% (243) | hypothetical protein MLBr_00468 |
| M. abscessus ATCC 19977 | MAB_1170 | - | 2e-22 | 32.58% (264) | hypothetical protein MAB_1170 |
| M. marinum M | MMAR_2104 | speE | 7e-05 | 23.87% (222) | spermidine synthase, SpeE |
| M. avium 104 | MAV_3519 | - | 8e-09 | 26.64% (244) | hypothetical protein MAV_3519 |
| M. smegmatis MC2 155 | MSMEG_5387 | - | 1e-112 | 72.07% (290) | hypothetical protein MSMEG_5387 |
| M. thermoresistible (build 8) | TH_4293 | - | 1e-125 | 76.79% (293) | PUTATIVE putative protein of unknown function DUF81 |
| M. ulcerans Agy99 | MUL_1708 | speE | 4e-05 | 23.87% (222) | spermidine synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1828|M.vanbaalenii_PYR-1 -------MIALTIGLAVFVG-------IALGLLGGGGSILTVPLLAYVAG
Mflv_0983|M.gilvum_PYR-GCK -------MMALTVGLAVFVG-------IALGLLGGGGSILTVPLLAYVAG
TH_4293|M.thermoresistible__bu -------MIGLIIALAVLVG-------VALGLLGGGGSILMVPLLAYVAG
MSMEG_5387|M.smegmatis_MC2_155 -------MIALTIVLAVFVG-------IALGMLGGGGSILTVPLLAYVAG
MLBr_00468|M.leprae_Br4923 ----MLVSHLATIGLAGFGA-------GAINALVGSGTLITFPTLVALGY
MAV_3519|M.avium_104 ---------MFVICLAGLAA-------GAINALVGSGTLITFPTLVALGY
Mb2902c|M.bovis_AF2122/97 -------MNEALIGLAFAAG--------LVAALNPCGFAMLPAYLLLVVH
Rv2877c|M.tuberculosis_H37Rv -------MNEALIGLAFAAG--------LVAALNPCGFAMLPAYLLLVVY
MMAR_2104|M.marinum_M MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIYELALLTLSTS
MUL_1708|M.ulcerans_Agy99 MTATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTS
MAB_1170|M.abscessus_ATCC_1997 --MTERPGVGTLARIGVLGG-------MSGGLLGGGTGVITVPSLARATT
. . *
Mvan_1828|M.vanbaalenii_PYR-1 --MDAKAAIATSLLVVGVTSAIG--AISHAR----AGRVQWRTGLIFGAA
Mflv_0983|M.gilvum_PYR-GCK --MDAKQAIATSLLVVGVTSAIG--AVSHAR----AGRVQWRTGLIFGAA
TH_4293|M.thermoresistible__bu --MDAKAAIATSLLVVGVTSAVG--AVSHAR----AGQVRWRTGLIFGAA
MSMEG_5387|M.smegmatis_MC2_155 --MDAKQAVTTSLLVVGVTSAVS--AVSHAR----AGRVQWRAGLSFGAA
MLBr_00468|M.leprae_Br4923 SPVTSTMSNAVGLVAGGVSATWGYRAELGDR----WSRLRWQIPMSLTGA
MAV_3519|M.avium_104 PPVTATMSNATGLVAGSVSGTWGYRAELRGQ----WDRLRWQLPASLAGA
Mb2902c|M.bovis_AF2122/97 --GQDSAGRTGPLSAVGRAAAATVGMALG-------------FLTVFGIF
Rv2877c|M.tuberculosis_H37Rv --GQDSAGRTGPLSAVGRAAAATVGMALG-------------FLTVFGIF
MMAR_2104|M.marinum_M --LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGII
MUL_1708|M.ulcerans_Agy99 --LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGMI
MAB_1170|M.abscessus_ATCC_1997 ---LSRAVIHGTATLPNVSAAIAGSTVYALHG----AKVDVVAGAGLMAG
. .: :
Mvan_1828|M.vanbaalenii_PYR-1 GMAG----AYAGGLLARYIPGTILLIGFAVMMIATAIAMLRGRKTIETGE
Mflv_0983|M.gilvum_PYR-GCK GMAG----AYAGGLLARFIPGTVLLIGFALMMIATAVAMLRGRKNVQATE
TH_4293|M.thermoresistible__bu GMAG----AYAGGILARFIPGTVLLLGFAVMMAATAVAMLRGRRNTATPD
MSMEG_5387|M.smegmatis_MC2_155 GMAG----AYAGGVLGRFIPGTALLIAFAVVMVAAAIPMLRGRR---APE
MLBr_00468|M.leprae_Br4923 ALGAFLLLHLPEKVFTAIVP-MLLVLALVLVVAGPRIQSWTRCRAKAAVN
MAV_3519|M.avium_104 GLGAYLLLHLPEKVFAEIVP-VLLVAALVLVVTGPRIQAWTARRAELAGR
Mb2902c|M.bovis_AF2122/97 GALT----ISAATAVQRYLPYATVLIGLALIALGGWLLLGRGLTALTPRS
Rv2877c|M.tuberculosis_H37Rv GALT----ISAATAVQRYLPYATVLIGLALIALGGWLLLGRGLTALTPRS
MMAR_2104|M.marinum_M GGLS----AAALYVAFAFIDGSTWVLALGTALIGG--LVGAEVPLLMTLL
MUL_1708|M.ulcerans_Agy99 GGLS----AAALYVAFAFIDGSTWVLALGTALIGG--LVGAEVPLLMTLL
MAB_1170|M.abscessus_ATCC_1997 GVIG----AVVGAKLVARIPEWILKALFVFVLLATAAKLLLSAAGIDPSA
. : : . .
Mvan_1828|M.vanbaalenii_PYR-1 TG--HRLPVPKIV--AEG--LIVGLVTGLVGAGGG----FLVVPALALLG
Mflv_0983|M.gilvum_PYR-GCK GS--HRLPVPKIL--AEG--LLVGLVTGLVGAGGG----FLVVPALALLG
TH_4293|M.thermoresistible__bu TGGDHRLPVPRIL--ADG--LVVGLVTGLVGAGGG----FLVVPALALLG
MSMEG_5387|M.smegmatis_MC2_155 ATTAHGLPVVRVV--SLG--LAVGGLTGMIGAGGG----FLVVPALTLLG
MLBr_00468|M.leprae_Br4923 RAEHTTPAQMAML--ALGT-FAVSVYGGYFTAGQG----ILLVSLMSILL
MAV_3519|M.avium_104 SPEHVPPGRMATL--VFGT-FAVGVYGGYFTAAQG----ILLVGLMGALL
Mb2902c|M.bovis_AF2122/97 LGVRWAPTVRLGS--MYG--YGISYAVASLSCTIGP---FLAVTGAGLRG
Rv2877c|M.tuberculosis_H37Rv LGVRWAPTVRLGS--MYG--YGISYAVASLSCTIGP---FLAVTGAGLRG
MMAR_2104|M.marinum_M QRGRLAEAADTGR--TLANLNAADYLGALIGGLVWP---FVLLPHLGMIR
MUL_1708|M.ulcerans_Agy99 QRGRLAEAADTGR--TLANLNAADYLGALIGGLVWP---FVLLPHLGMIR
MAB_1170|M.abscessus_ATCC_1997 GEALLPEGVLAHVPSVIAIGAVVGFVVGAWSAALGLGGGLLTVPAMLVLF
. . . :: :
Mvan_1828|M.vanbaalenii_PYR-1 GLPMP--------------------------------IAVGTSLIVIAMK
Mflv_0983|M.gilvum_PYR-GCK GLPMP--------------------------------VAVGTSLIVIAMK
TH_4293|M.thermoresistible__bu GLSMP--------------------------------AAVGTSLVVIAMK
MSMEG_5387|M.smegmatis_MC2_155 GLPMP--------------------------------AAVGTSLIVIALN
MLBr_00468|M.leprae_Br4923 PESMQR-------------------------------INAAKNLLSMLVN
MAV_3519|M.avium_104 PESVQR-------------------------------MNAAKNLLALVVN
Mb2902c|M.bovis_AF2122/97 GSVVG---------SVAIYLA---------------YVAGLTLVVGVLAV
Rv2877c|M.tuberculosis_H37Rv GSVVG---------SVAIYLA---------------YVAGLTLVVGVLAV
MMAR_2104|M.marinum_M GAAATGIVNLVAAAVVSIFLLRQVVSTRQLAMALSSLLAALGLLVTLLVH
MUL_1708|M.ulcerans_Agy99 GAAATGIVNLVAAAVVSIFLLRQVVSTRQLAMALCSLLAALGLLVTLLVH
MAB_1170|M.abscessus_ATCC_1997 GSELH--------------------------------VAEGTSLMVMLPN
:: :
Mvan_1828|M.vanbaalenii_PYR-1 SFAGLAGYLTSVH-INWTLALAVTAAAVIGALIGARLTAMINPDSLRKTF
Mflv_0983|M.gilvum_PYR-GCK SFAGLGGYLSSVQ-IDWSLALAVTAAAVVGALLGARLTSMVNPDSLRKAF
TH_4293|M.thermoresistible__bu SFAGLAGYLTSVQ-IDWPVALAVTVAAVAGALLGSRLTALVNPDTLRQAF
MSMEG_5387|M.smegmatis_MC2_155 SFSGLAGHLTGLQ-IDWALAAAVTGAAVAGCLIGTRLITKINADALRKAF
MLBr_00468|M.leprae_Br4923 LTAAVGYTLVAFDRINWSAAGMIAASSLVGGLVGTRYARRLSPNVLRATI
MAV_3519|M.avium_104 VVAAVAYTSVAFGRISWAAAGLIAAGSLVGGLLGARYGRRLSGGALRAII
Mb2902c|M.bovis_AF2122/97 AAATASSALADRLRRILPFVNRISGALLVVVG------LYVG--------
Rv2877c|M.tuberculosis_H37Rv AAATASSALADRLRRILPFVNRISGALLVVVG------LYVG--------
MMAR_2104|M.marinum_M ARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTR
MUL_1708|M.ulcerans_Agy99 ARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTR
MAB_1170|M.abscessus_ATCC_1997 ALVAATTHLRQGT-ADAPIGFRLAAFALPGTVIGALLALALNARWLALVF
: : :.
Mvan_1828|M.vanbaalenii_PYR-1 GWFVLVMSSVILAQEIHPAVGITAAALT----------------------
Mflv_0983|M.gilvum_PYR-GCK GWFVLAMSSVILAQEIHLAVGIAGAALT----------------------
TH_4293|M.thermoresistible__bu GWFVLTMSAVILAQEAHPAVGAAAAVLT----------------------
MSMEG_5387|M.smegmatis_MC2_155 GWFVLAMSSVILAQEIHPFVGLAAASLT----------------------
MLBr_00468|M.leprae_Br4923 VAIGLIGLVRLLAV------------------------------------
MAV_3519|M.avium_104 VVVGLIGLYRLLAVA-----------------------------------
Mb2902c|M.bovis_AF2122/97 -YYGLYELRLIAGVGANPQDAVIAAAG-----------------------
Rv2877c|M.tuberculosis_H37Rv -YYGLYELRLIAGVGANPQDAVIAAAG-----------------------
MMAR_2104|M.marinum_M DEYRYTESLVYPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELD
MUL_1708|M.ulcerans_Agy99 DEYRYTESLVYPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELD
MAB_1170|M.abscessus_ATCC_1997 GSYLVFIAVREIVRAIRTAAAKTKKSGP----------------------
Mvan_1828|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0983|M.gilvum_PYR-GCK --------------------------------------------------
TH_4293|M.thermoresistible__bu --------------------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 ---------------------------------RLQGALAG---------
Rv2877c|M.tuberculosis_H37Rv ---------------------------------RLQGALAG---------
MMAR_2104|M.marinum_M PAVIELARTTMREANGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFDAVI
MUL_1708|M.ulcerans_Agy99 PAVIELARTTMREANGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFDAVI
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1828|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0983|M.gilvum_PYR-GCK --------------------------------------------------
TH_4293|M.thermoresistible__bu --------------------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 --------------------------------WVNQHG------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------WVNQHG------------
MMAR_2104|M.marinum_M VDLPDPDTPALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRT
MUL_1708|M.ulcerans_Agy99 VDLPDPDTPALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRT
MAB_1170|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1828|M.vanbaalenii_PYR-1 --------LIAAATTLACQRYAHCPLSRLTTRLTTPKAAA----------
Mflv_0983|M.gilvum_PYR-GCK --------AIAALMTFACSRYAHCPLRRITGIGAARGAHA----------
TH_4293|M.thermoresistible__bu --------AVAAALTFTCSRYGRCPLRRVAEALSSRPATA----------
MSMEG_5387|M.smegmatis_MC2_155 --------VIAASMTMVCARFSRCPLRRVTRLSMARPAVA----------
MLBr_00468|M.leprae_Br4923 --------------------------------------------------
MAV_3519|M.avium_104 --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 -----AWPWAVLLVVLVVGAFAGTWFRRVRR-------------------
Rv2877c|M.tuberculosis_H37Rv -----AWPWAVLLVVLVVGAFAGTWFRRVRR-------------------
MMAR_2104|M.marinum_M VSTIKAAGYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFL
MUL_1708|M.ulcerans_Agy99 VSTIKAAGYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFL
MAB_1170|M.abscessus_ATCC_1997 ----------APVPQVCVGG------------------------------
Mvan_1828|M.vanbaalenii_PYR-1 -----------------------------------------
Mflv_0983|M.gilvum_PYR-GCK -----------------------------------------
TH_4293|M.thermoresistible__bu -----------------------------------------
MSMEG_5387|M.smegmatis_MC2_155 -----------------------------------------
MLBr_00468|M.leprae_Br4923 -----------------------------------------
MAV_3519|M.avium_104 -----------------------------------------
Mb2902c|M.bovis_AF2122/97 -----------------------------------------
Rv2877c|M.tuberculosis_H37Rv -----------------------------------------
MMAR_2104|M.marinum_M NQPVLNAATVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR--
MUL_1708|M.ulcerans_Agy99 NQPVLNAATVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC
MAB_1170|M.abscessus_ATCC_1997 -----------------------------------------