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MLKVGIIGAGGVARAHARALNTLKSAELVGVLDIDARAAESFTDAYGGTPVTDVDALLELADAVVVASPN FTHRDHSLSALRAGRSVLCEKPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGT ICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVHLLDLLTYISGGRILVDECQARITTHVTNKS DEAVEVDDHAEIYGRLSTGSIFTLVASKAAPAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVD LARTLLSDPDNEVHGWSDSFRSEIDHWSRLVAVGGGANRQALATFDDGLAAQEVLESLLRGSKPQPERLP VEHTLPTPAEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2612 | - | - | 100% (361) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2306c | - | 2e-10 | 25.56% (223) | putative oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2613 | - | 3e-13 | 22.41% (348) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2628 | - | 3e-12 | 31.08% (148) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_1941 | - | 2e-17 | 28.10% (363) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. smegmatis MC2 155 | MSMEG_6717 | - | 4e-19 | 31.47% (251) | oxidoreductase, Gfo/Idh/MocA family protein |
| M. thermoresistible (build 8) | TH_3104 | - | 4e-14 | 26.32% (285) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 9e-13 | 24.62% (195) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2613|M.gilvum_PYR-GCK ------MTSLGLIGLGRIG-AFHTETLINLPEVSRLVITDERPGVVGEVA
Mvan_3968|M.vanbaalenii_PYR-1 ------MTTLGLIGLGRIG-AFHAETLTNLPEVSGLVVTDERPEVVSQLA
MSMEG_6717|M.smegmatis_MC2_155 --MVGHALRIGIIGAGVMG-TKHAEYVAREQDATVVAVADP---FSRTLA
MAV_1941|M.avium_104 -----MTLRVGIIGVGWGA-HVQVPGFRAAKGYEPVALCARTPERLERVA
TH_3104|M.thermoresistible__bu -------MRVLVIGTGFGR-QAMAPVYRG-LGFDVEVVSPRDESALHRAL
MAB_2612|M.abscessus_ATCC_1997 ------MLKVGIIGAGGVA-RAHARALNTLKSAELVGVLDIDARAAESFT
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARAQAFA
: ::* . . :
Mflv_2613|M.gilvum_PYR-GCK AKYGATPVES-VEKLLSS-GIDGVVVAAATPAHAELTLAAVERGLPTFCE
Mvan_3968|M.vanbaalenii_PYR-1 TKYGATPANS-VQELLAS-GVDGVIVAAATPAHAELTLAAVERGLPTFCE
MSMEG_6717|M.smegmatis_MC2_155 GKLGVPHFDS-YHDLLAASGAEAVIIANPNSAHVETTLAAIEARIPALLE
MAV_1941|M.avium_104 DKLGIEETSTDWESFVTRDDLDVISVATPTVLHRDMTLAALAAGKPVLCE
TH_3104|M.thermoresistible__bu N-----------------AGVDLVSVHSPPFLHRQHVTAAVDRGYPVLCD
MAB_2612|M.abscessus_ATCC_1997 DAYGGTPVTD---VDALLELADAVVVASPNFTHRDHSLSALRAGRSVLCE
MMAR_2628|M.marinum_M AKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHVLCE
: : : . * :*: .: :
Mflv_2613|M.gilvum_PYR-GCK KPIASTAAESARVAEIIARSGVPVQVGYQRRFDTAFAAVKQAADSGSLG-
Mvan_3968|M.vanbaalenii_PYR-1 KPIAATAAESARVGEVITRSGVPVQVGYQRRFDAAFAAVKHAVDDGSLG-
MSMEG_6717|M.smegmatis_MC2_155 KPVAVTAAEAAHLVAAVRDSDTVVLVGHHRRHHPAVSKARNLIASGVIG-
MAV_1941|M.avium_104 KPLAGDLDAARDMVRAAAEANVPTACCFENRWNPDWLAVADRVRSGFLGT
TH_3104|M.thermoresistible__bu KPFGRNADEARAMRDHAARRAVPTFLNFELRHQPARAEFKKLADSGVIG-
MAB_2612|M.abscessus_ATCC_1997 KPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGT
MMAR_2628|M.marinum_M KPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASGELG-
**. : : . .. * . * :*
Mflv_2613|M.gilvum_PYR-GCK ---ALHTVRSTTMDPAPP---PMDYIRGSGG-IFRDCAVHDFDVIRWVTG
Mvan_3968|M.vanbaalenii_PYR-1 ---ALHTVRSTTMDPAPP---PMDYIKGSGG-IFRDCAVHDFDVIRWVTG
MSMEG_6717|M.smegmatis_MC2_155 ---RLVAVNGMWLTKKSDDYFEQRWRRETGAGVMLINLVHDLDLARYLCG
MAV_1941|M.avium_104 QYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLCSLLG
TH_3104|M.thermoresistible__bu --TPRHLSWTFFGAGLRGRPHGWINERDTGGGWIGANGAHLIDYTRYLFG
MAB_2612|M.abscessus_ATCC_1997 ICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVHLLDLLTYISG
MMAR_2628|M.marinum_M ----TLQRVETSMCFPLPKFSDIRYNYALAGGATMDAGCYAVHMARTFGG
. : .. . *
Mflv_2613|M.gilvum_PYR-GCK QN----VVEVYATGSVQGDPL--FTEYGDVDTAAIVVRFDGGALG--VVS
Mvan_3968|M.vanbaalenii_PYR-1 QN----VVDVYATGSVQGDPR--FAEYGDVDTAAVVVRFDGGALG--VVS
MSMEG_6717|M.smegmatis_MC2_155 EIT---TVQAVSSNALRG--------FEVEDTAAVIVGFDNGAIGTFILS
MAV_1941|M.avium_104 RPVS-VCAEVRTSDPVRELPDGGTLHVTADDTAAVLMRMESGVTA--VLS
TH_3104|M.thermoresistible__bu SEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTA--THD
MAB_2612|M.abscessus_ATCC_1997 GRILVDECQARITTHVTNKSD---EAVEVDDHAEIYGRLSTGSIFT-LVA
MMAR_2628|M.marinum_M GTP-----EVVSAQAKRRDSE-------VDRAMTAELRFPAGHSG--RIQ
. *
Mflv_2613|M.gilvum_PYR-GCK AARYNGRGYDCRLEVHG--FDDTVVAGWDQGAPVRNADP----------A
Mvan_3968|M.vanbaalenii_PYR-1 AARYNGRGYDCRLEVHG--FDDTVVAGWDQGAPVRNADPDFSS------P
MSMEG_6717|M.smegmatis_MC2_155 DSAVAPWGWDQATQDDPQFPCNPDIPAWSIAGTTGSLTFPQLARFYHQGE
MAV_1941|M.avium_104 VSVMGAHADHYRLELFG--SDGTIIGDGDLRSAAYSLGAATDDGLRSLAV
TH_3104|M.thermoresistible__bu TAFAAAVALPPRMVLTG--SAGALELIGDSRLIVHRADADPMT-------
MAB_2612|M.abscessus_ATCC_1997 SKAAPAADCGFSIRIVG---TNAVFRYHTADPGRYLVSRGADTETVDLAR
MMAR_2628|M.marinum_M CSMWSSHLLNMSARVVG---DRGELRVLNPVVPQLFHRLTVQS-------
Mflv_2613|M.gilvum_PYR-GCK NDFPTGQPHHF---FMDRFTEAFRTELSSFVDVVEGG----PNLGATVAD
Mvan_3968|M.vanbaalenii_PYR-1 GAFPAGPPHHF---FMDRFTEAFRAELRAFVDVVEGG----PIRGATVAD
MSMEG_6717|M.smegmatis_MC2_155 SDWYQPLSRRY---ESTDAGDSYTRQLQHFIAVARGD----AAPLVTVED
MAV_1941|M.avium_104 DEREPAHPDRLPRGLAGHASRAMALMLQDWLPAFDGA----PSNVATFED
TH_3104|M.thermoresistible__bu HEFPPAPPRSF-------YEPALTPWLEQVADALRTG----RPATPSFDD
MAB_2612|M.abscessus_ATCC_1997 TLLSDPDNEVHG------WSDSFRSEIDHWSRLVAVGGGANRQALATFDD
MMAR_2628|M.marinum_M --AIGRRVERFP------RRASYAYQLDAFTGAILRG----EAVKTTPQD
: : : *
Mflv_2613|M.gilvum_PYR-GCK AVEVAWIAEAATESLR-RGVPVTIDSVRKEAQQ---
Mvan_3968|M.vanbaalenii_PYR-1 AVEVAWIAEAATESLR-RGVPVTIESVRKETQQ---
MSMEG_6717|M.smegmatis_MC2_155 AAASLTVIEVAQRAAK-CGHRLDVPMVSAPTGKTTE
MAV_1941|M.avium_104 GLLSLAIIDAARRSAE-GGGWEPVQA----------
TH_3104|M.thermoresistible__bu GVAVAEVMDRLRANVI-EQVMQ--------------
MAB_2612|M.abscessus_ATCC_1997 GLAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL--
MMAR_2628|M.marinum_M AVQNMTVIDAIYRAAG-----LPLRNPS--------
. : :