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TTLKLTVAAIDDTIAGIRTLTLTHVDEAPLPSFTPGSHLVVECGARNGPANAYSLTGDGIAPAAYVISVL RAGTSGEAPSGSRWIHDELAVGDTVLARPPRSAFAPILRARRHLLVAAGIGITPMVSHLRSARLWGRDAR LLYIHRPGRGAYVDTVRSLTDHASIHTLREEFVAELSTALADQPLGTHLYVCGPASFIDFVAATATELGW PASRIHFEHFGAGALDPGEPFTVRVPSTADEFTVEAGVSLLEALESRGFAIPNLCRRGVCGECRVPVSGG AITHRDLYLSDDEKRAGNSMMACVSRAASQSLELKL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3958 | - | - | 100% (317) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_3180 | - | 2e-34 | 36.46% (288) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_2893 | - | 3e-19 | 24.30% (321) | ferredoxin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2798c | - | 9e-24 | 29.73% (296) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2623 | - | 1e-135 | 78.41% (301) | ferredoxin |
| M. tuberculosis H37Rv | Rv2776c | - | 9e-24 | 29.73% (296) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2381 | - | 6e-38 | 33.02% (318) | oxidoreductase |
| M. marinum M | MMAR_1933 | - | 2e-24 | 29.49% (295) | oxidoreductase |
| M. avium 104 | MAV_4119 | - | 2e-26 | 28.66% (314) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4638 | - | 1e-107 | 60.51% (314) | vanillate O-demethylase oxidoreductase |
| M. thermoresistible (build 8) | TH_3804 | - | 1e-36 | 36.36% (319) | PUTATIVE ferredoxin |
| M. ulcerans Agy99 | MUL_2159 | - | 4e-25 | 29.83% (295) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2798c|M.bovis_AF2122/97 --------------------------------------------------
Rv2776c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1933|M.marinum_M MAVSESSWTSRPADLYGRSHRDRFATALWGVRTMFGGFARFSRWNPSRVT
MUL_2159|M.ulcerans_Agy99 MAVSESSWTSRPADLYGRSHRDRFATALWGVRTMFGGFARFSRWNPSRVT
MAV_4119|M.avium_104 MTMAQAIWESIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVV
TH_3804|M.thermoresistible__bu MRMLARLRATPPSSS-GRIRHDLLLGVADATISSLWKVSEVLR-TPRLPA
MAB_2381|M.abscessus_ATCC_1997 ------------------------------------------------MN
Mvan_3958|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2623|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4638|M.smegmatis_MC2_155 --------------------------------------------------
Mb2798c|M.bovis_AF2122/97 -MRRTNPAVVTKRE----LVAP--DVVALTLADPGGGLLPAWSPGGHIDV
Rv2776c|M.tuberculosis_H37Rv -MRRTNPAVVTKRE----LVAP--DVVALTLADPGGGLLPAWSPGGHIDV
MMAR_1933|M.marinum_M PVGRTHRARVVERE----LVAP--DVVALTLADPDGGLLPSWSPGGHIDV
MUL_2159|M.ulcerans_Agy99 PVGRTHRARVVERE----LVAP--DVVALTLADPDGGLLPSWSPGGHIDV
MAV_4119|M.avium_104 PVRRTTTAVVTQRE----ELAP--DVVAFTLADPHGGLLPSWTPGAHIDV
TH_3804|M.thermoresistible__bu VDAEPITLTVRDRR----VVAHDQDVIALTLVAADGGQLPPWRPGAHIDV
MAB_2381|M.abscessus_ATCC_1997 DTGATLKVAVRQLR----WEAD--GVVSLQLSSACNEPLPAWEPGAHVDL
Mvan_3958|M.vanbaalenii_PYR-1 --MTTLKLTVAAIDDTIA------GIRTLTLTHVDEAPLPSFTPGSHLVV
Mflv_2623|M.gilvum_PYR-GCK ----------------------------MTLTHVDGAPLPSFTPGSHIVV
MSMEG_4638|M.smegmatis_MC2_155 MTQPVMQLVITEIDDSVP------GVRTLRLAHPEGRALPSYPPGSHVVL
: * **.: **.*: :
Mb2798c|M.bovis_AF2122/97 QLPS--GRRRQYSLCGVPGRRTDYRIAIRRIADGGG----GSIEMHEAFD
Rv2776c|M.tuberculosis_H37Rv QLPS--GRRRQYSLCGVPGRRTDYRIAIRRIADGGG----GSIEMHEAFD
MMAR_1933|M.marinum_M QLPS--GRRRQYSLCGPPGRRTDYRIAVRRIADGGG----GSIEMHAAYQ
MUL_2159|M.ulcerans_Agy99 QLPS--RRRRQYSLCGPPGRRTDYRIAVRRIADGGG----GSIEMHAAYQ
MAV_4119|M.avium_104 RLPS--GRRRQYSLCGPPGRRTDYRIAVRRIEDGGG----GSIEMHDTFR
TH_3804|M.thermoresistible__bu TLPS--GRVRQYSLCGDPAVRDRYRIAVRRIPDGGG----GSVEVHDALH
MAB_2381|M.abscessus_ATCC_1997 VLPT--GIERQYSLCGPVDDRSVYQVGVRRERTSRG----GSEYVHAFLR
Mvan_3958|M.vanbaalenii_PYR-1 ECGARNGPANAYSLTGDGIAPAAYVISVLR-AGTSGEAPSGSRWIHDELA
Mflv_2623|M.gilvum_PYR-GCK ECEAPGRPTNAYSLTGDGIAPDAYVISVLRRADEITSGPSGSQWIHDELA
MSMEG_4638|M.smegmatis_MC2_155 QCGD---VANAYSLTGDGVSPMRYVVSVLLCPNGSG----GSRWIHDEVR
. *** * * :.: ** :*
Mb2798c|M.bovis_AF2122/97 VGDTCEFEGPRNAFHLGLA-----ERDVLFVIGGIGVTPILPMIRAAEQR
Rv2776c|M.tuberculosis_H37Rv VGDTCEFEGPRNAFHLGLA-----ERDVLFVIGGIGVTPILPMIRAAEQR
MMAR_1933|M.marinum_M PGDILVFEGPRNAFYLGAA-----EHDMLFVIGGIGVTPILPMVALAHQR
MUL_2159|M.ulcerans_Agy99 PGDILVFEGPRNAFYLGAA-----EHDMLFVIGGIGVTPILPMVALAHQR
MAV_4119|M.avium_104 VGDALEFEGPRNAFYLVTD-----ERDVLFVIGGIGVTPILPMIQTAQQH
TH_3804|M.thermoresistible__bu LGARVTTHGPRNAFPLSVPGYGSPARRLRFIAGGIGITPILPMLAEAQAF
MAB_2381|M.abscessus_ATCC_1997 PGQQLRIKGPRNNFGLHRA------DGYLFIAAGIGITPILPMIRQAQDW
Mvan_3958|M.vanbaalenii_PYR-1 VGDTVLARPPRSAFAPILR-----ARRHLLVAAGIGITPMVSHLRSARLW
Mflv_2623|M.gilvum_PYR-GCK VGDTLIARPPRSAFAPVLR-----ARRHLLVAAGIGITPMVSHLRSAKLW
MSMEG_4638|M.smegmatis_MC2_155 IGETIDVSAPRSAFAPVHK-----ARRHLLVAAGIGITPMMSHLYSAKRW
* **. * :: .***:**::. : *.
Mb2798c|M.bovis_AF2122/97 GIDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDELLAG
Rv2776c|M.tuberculosis_H37Rv GIDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDELLAG
MMAR_1933|M.marinum_M GVNWRAMYAGRSREYMPLLDELVAMAPERVSVWADDEHGRFAQVEDLVAG
MUL_2159|M.ulcerans_Agy99 GVNWRAVYAGRSREYMPLLDELVAMAPEGVSVWADDEHGRFAQVEDLVAG
MAV_4119|M.avium_104 GINWRAVYAGRSRDYMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAE
TH_3804|M.thermoresistible__bu GVPWSMIYAGRSRDSLPFLEELTRYG-DRVRVRTDDVAG-LPTAAELLGA
MAB_2381|M.abscessus_ATCC_1997 GADWTLYYGGHTAASMAFLEELRQYG-PRVHLYPADEVGRIPLR-ELTTD
Mvan_3958|M.vanbaalenii_PYR-1 GRDARLLYIHRPGR-GAYVDTVRSLT--DHASIHTLREEFVAELSTALAD
Mflv_2623|M.gilvum_PYR-GCK GRETRLYYIHRPGR-AAYVDTIRELT--DHASIHTERAQFATDVSVALAD
MSMEG_4638|M.smegmatis_MC2_155 GADARLLYIHRAGR-GAYLDEVEQLG--MPARVCTDRDRFHSELTAALIS
* * : . :: : .
Mb2798c|M.bovis_AF2122/97 AGPTTAVYVCGPPGMLEAVRVARNQH--ADAPLHYERFSPPPVVDG--VP
Rv2776c|M.tuberculosis_H37Rv AGPTTAVYVCGPPGMLEAVRVARNQH--ADAPLHYERFSPPPVVDG--VP
MMAR_1933|M.marinum_M AGPKTAVYVCGPPPMLEAVRAARAEY--PCAPLHYERFSPPPVVDG--VP
MUL_2159|M.ulcerans_Agy99 AGLKTAVYVCGPPPMLEAVRAARAEY--PCAPLHYERFSPPPVVDG--VP
MAV_4119|M.avium_104 AGPATAVYVCGPTAMLEAVRTARDEH--ADAPLHYERFGPPPVVDG--VP
TH_3804|M.thermoresistible__bu CPDGTAVYACGPPAMLTAIRAELAGR--RNVELHFERFAAPPVVDG--RP
MAB_2381|M.abscessus_ATCC_1997 VRPGLQIYACGPTELISDLTAAVSHW--PADTLHVERFKPIPCAPAEDKP
Mvan_3958|M.vanbaalenii_PYR-1 QPLGTHLYVCGPASFIDFVAATATELGWPASRIHFEHFGAGALDPG--EP
Mflv_2623|M.gilvum_PYR-GCK QPMGTHLYVCGPAGFIEFVSATAAALGWPASRIHIEHFGSEALDPG--EP
MSMEG_4638|M.smegmatis_MC2_155 QPIGTHLYVCGPGTFMDDVIAQARELGWPPSRIHSERFGVDALDAG--EP
:*.*** :: : . :* *:* . . *
Mb2798c|M.bovis_AF2122/97 FELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVLAG
Rv2776c|M.tuberculosis_H37Rv FELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVLAG
MMAR_1933|M.marinum_M FELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVLAG
MUL_2159|M.ulcerans_Agy99 FELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVLAG
MAV_4119|M.avium_104 FELELARSRRVLTVPGNRSALDVMLDRDPATPYSCQQGFCGTCKVKVLAG
TH_3804|M.thermoresistible__bu FSVRIASTGAEVPVGADETLLAALGRAGVQAPYSCQQGFCGTCRTRVLDG
MAB_2381|M.abscessus_ATCC_1997 VDVTCAASRQTIAVPPGQSILAAVEQAGIQVSASCRAGVCGSCETAVLEG
Mvan_3958|M.vanbaalenii_PYR-1 FTVRVPSTADEFTVEAGVSLLEALESRGFAIPNLCRRGVCGECRVPVSGG
Mflv_2623|M.gilvum_PYR-GCK FSVRVRSTGEEFPVEPGVSLLEALERRGFDIPNLCRRGVCGECRIPVSGS
MSMEG_4638|M.smegmatis_MC2_155 FEVELAGTGQTLTVPSGVSLLEALEKNGQNVPNLCRQGVCGECRIPVARG
. : : . : . : * .: . . *: *.** *. * .
Mb2798c|M.bovis_AF2122/97 QVDRRGRIIE-----GDNEMLVCVSRAVS-GRVVIDA
Rv2776c|M.tuberculosis_H37Rv QVDRRGRIIE-----GDNEMLVCVSRAVS-GRVVIDA
MMAR_1933|M.marinum_M QVDHRGRAAQ-----GDDEMLVCVSRGHS-ARVVIDA
MUL_2159|M.ulcerans_Agy99 QVDHRGRAAQ-----GDDEMLVCVSRGHS-ARVVIDA
MAV_4119|M.avium_104 QVDRRGRTVE-----GDDEMLVCVSRAKN-DRLVIDA
TH_3804|M.thermoresistible__bu TVEHRDRLLTEPE-RAAGLMLTCVSRAPAGERLTLDL
MAB_2381|M.abscessus_ATCC_1997 VPDHRDDILSEEDRAAGDRMYICVSRALT-PRLVLDL
Mvan_3958|M.vanbaalenii_PYR-1 AITHRDLYLSDDEKRAGNSMMACVSRA-ASQSLELKL
Mflv_2623|M.gilvum_PYR-GCK VITHRDLYLTEDDKVAGDSLMACVSRADGSQTLEVAL
MSMEG_4638|M.smegmatis_MC2_155 DILHRDTYLSDDEKQAGDALMACVSRA-AGERLELAL
:*. . . : ****. : :