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MAVSESSWTSRPADLYGRSHRDRFATALWGVRTMFGGFARFSRWNPSRVTPVGRTHRARVVERELVAPDV VALTLADPDGGLLPSWSPGGHIDVQLPSRRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHAAYQPG DILVFEGPRNAFYLGAAEHDMLFVIGGIGVTPILPMVALAHQRGVNWRAVYAGRSREYMPLLDELVAMAP EGVSVWADDEHGRFAQVEDLVAGAGLKTAVYVCGPPPMLEAVRAARAEYPCAPLHYERFSPPPVVDGVPF ELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVLAGQVDHRGRAAQGDDEMLVCVSR GHSARVVIDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2159 | - | - | 100% (360) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4142 | hmp | 9e-18 | 27.73% (321) | flavodoxin reductase Hmp |
| M. ulcerans Agy99 | MUL_4117 | fdxB | 2e-13 | 25.21% (353) | electron transfer protein FdxB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2798c | - | 1e-142 | 78.96% (309) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3426 | - | 2e-66 | 44.78% (335) | ferredoxin |
| M. tuberculosis H37Rv | Rv2776c | - | 1e-142 | 78.96% (309) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0088c | - | 3e-78 | 47.51% (362) | putative oxidoreductase |
| M. marinum M | MMAR_1933 | - | 0.0 | 98.89% (360) | oxidoreductase |
| M. avium 104 | MAV_4119 | - | 1e-155 | 73.61% (360) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3676 | - | 1e-70 | 43.13% (371) | phenoxybenzoate dioxygenase beta subunit |
| M. thermoresistible (build 8) | TH_3804 | - | 8e-72 | 48.72% (312) | PUTATIVE ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_3180 | - | 6e-71 | 48.40% (312) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3676|M.smegmatis_MC2_155 ---MLSQYRQL------------PPSTNGRFRHDPMLAMAQIAIKTMWGV
TH_3804|M.thermoresistible__bu -MRMLARLRAT------------PPSSSGRIRHDLLLGVADATISSLWKV
Mflv_3426|M.gilvum_PYR-GCK ------------------------MGVLGRLRYDVTIGLADAALHGMFAT
Mvan_3180|M.vanbaalenii_PYR-1 MTRLFSQFRQT------------PPSPSGRLRHDVMLGIAETAIAGMFAA
MAB_0088c|M.abscessus_ATCC_199 ---MFDRFRHTGQPTSKRKRPSLPPTLYGTLPVSPTIALGTALFPVAVRA
MUL_2159|M.ulcerans_Agy99 -MAVSESSWTS-----------RPADLYGRSHRDRFA-TALWGVRTMFGG
MMAR_1933|M.marinum_M -MAVSESSWTS-----------RPADLYGRSHRDRFA-TALWGVRTMFGG
Mb2798c|M.bovis_AF2122/97 --------------------------------------------------
Rv2776c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4119|M.avium_104 -MTMAQAIWES-----------IPADLYGRRKRDRMY-TALYGVGALFGG
MSMEG_3676|M.smegmatis_MC2_155 TRHIRRPSPPPA--LDRTIGLRVVDRRVVAHDQDVIALTLAADDGGALPR
TH_3804|M.thermoresistible__bu SEVLRTPRLPAV--DAEPITLTVRDRRVVAHDQDVIALTLVAADGGQLPP
Mflv_3426|M.gilvum_PYR-GCK SAAMRRIRPPDG--VPETFPLTVTSRRVVARDQDVVELTLSGDD---LPR
Mvan_3180|M.vanbaalenii_PYR-1 SAAVRRVRMPAA--GPDTIPLTVTGRRVVAHDQDVVELTLAGDR---LPR
MAB_0088c|M.abscessus_ATCC_199 IGALLILKKPPENHVDRTLKLVVKDRWIEAKDQDVASLVLASPDGDRLPP
MUL_2159|M.ulcerans_Agy99 FARFSRWNPSRVTPVGRTHRARVVERELVAP--DVVALTLADPDGGLLPS
MMAR_1933|M.marinum_M FARFSRWNPSRVTPVGRTHRARVVERELVAP--DVVALTLADPDGGLLPS
Mb2798c|M.bovis_AF2122/97 --------------MRRTNPAVVTKRELVAP--DVVALTLADPGGGLLPA
Rv2776c|M.tuberculosis_H37Rv --------------MRRTNPAVVTKRELVAP--DVVALTLADPGGGLLPA
MAV_4119|M.avium_104 LASASRWTPARVVPVRRTTTAVVTQREELAP--DVVAFTLADPHGGLLPS
. * * * ** :.* **
MSMEG_3676|M.smegmatis_MC2_155 WYPGAHIDLHLPSGRIRQYSLCGDPAAG-TYRIAVRRIPEGGGGSVEIHD
TH_3804|M.thermoresistible__bu WRPGAHIDVTLPSGRVRQYSLCGDPAVRDRYRIAVRRIPDGGGGSVEVHD
Mflv_3426|M.gilvum_PYR-GCK WHPGAHLDLHLPSGRIRQYSLCGEPTAG-HYRVAVRRIPDGGGGSVEVHD
Mvan_3180|M.vanbaalenii_PYR-1 WFPGAHLDVHLPSGRVRQYSLCGDPDSA-EYRIAVRRIPDGGGGSVEVHD
MAB_0088c|M.abscessus_ATCC_199 WHPGAHLDLLLPSGRMRQYSLCGDVSDPYHYRIAVRRIPGGGGGSIEVHD
MUL_2159|M.ulcerans_Agy99 WSPGGHIDVQLPSRRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHA
MMAR_1933|M.marinum_M WSPGGHIDVQLPSGRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHA
Mb2798c|M.bovis_AF2122/97 WSPGGHIDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHE
Rv2776c|M.tuberculosis_H37Rv WSPGGHIDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHE
MAV_4119|M.avium_104 WTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRIAVRRIEDGGGGSIEMHD
* **.*:*: *** * ******* **:*:*** *****:*:*
MSMEG_3676|M.smegmatis_MC2_155 TVHIGSRLTTHGPRNAFPLTVPGYGSPTQRFRFIAGGIGITPILPMLDLA
TH_3804|M.thermoresistible__bu ALHLGARVTTHGPRNAFPLSVPGYGSPARRLRFIAGGIGITPILPMLAEA
Mflv_3426|M.gilvum_PYR-GCK ALPVGSTVRTHGPRNAFPLAVPGYGSPARRFRFIAGGIGITPILPMLALA
Mvan_3180|M.vanbaalenii_PYR-1 ALEIGSTVHTHGPRNAFPLTVPGYGSPARRFRFIAGGIGITPILPMLGLA
MAB_0088c|M.abscessus_ATCC_199 ALQIGATVSILGPRNAFPLAMTQPGP--RKLHFVAGGIGITPILSMIAFA
MUL_2159|M.ulcerans_Agy99 AYQPGDILVFEGPRNAFYLGAA-----EHDMLFVIGGIGVTPILPMVALA
MMAR_1933|M.marinum_M AYQPGDILVFEGPRNAFYLGAA-----EHDMLFVIGGIGVTPILPMVALA
Mb2798c|M.bovis_AF2122/97 AFDVGDTCEFEGPRNAFHLGLA-----ERDVLFVIGGIGVTPILPMIRAA
Rv2776c|M.tuberculosis_H37Rv AFDVGDTCEFEGPRNAFHLGLA-----ERDVLFVIGGIGVTPILPMIRAA
MAV_4119|M.avium_104 TFRVGDALEFEGPRNAFYLVTD-----ERDVLFVIGGIGVTPILPMIQTA
: * ****** * : . *: ****:****.*: *
MSMEG_3676|M.smegmatis_MC2_155 QRLGVDWSMIYAGRHPDSLPFLSELQRYG-DRIGIRTDDRDG-LPGASDL
TH_3804|M.thermoresistible__bu QAFGVPWSMIYAGRSRDSLPFLEELTRYG-DRVRVRTDDVAG-LPTAAEL
Mflv_3426|M.gilvum_PYR-GCK RSLGVDWSMVYTGRSADALPFVDEVAAFG-SPVEIRTDDRRG-LPTAAEL
Mvan_3180|M.vanbaalenii_PYR-1 RRLGVDWSMVYTGRSVDSLPFVDEVTAFG-AAVDIRTDDRHG-LPAAAEL
MAB_0088c|M.abscessus_ATCC_199 EQLGKPWTMVYTGRHRDSLPFLNELKRFG-DRVIIRTDDQSG-LPTADDL
MUL_2159|M.ulcerans_Agy99 HQRGVNWRAVYAGRSREYMPLLDELVAMAPEGVSVWADDEHGRFAQVEDL
MMAR_1933|M.marinum_M HQRGVNWRAMYAGRSREYMPLLDELVAMAPERVSVWADDEHGRFAQVEDL
Mb2798c|M.bovis_AF2122/97 EQRGIDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDEL
Rv2776c|M.tuberculosis_H37Rv EQRGIDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDEL
MAV_4119|M.avium_104 QQHGINWRAVYAGRSRDYMPLLDEVVAVAPERVSVWADDERGRIPTAADL
. * * :*:** : :*::.*: . : : :** * :. . :*
MSMEG_3676|M.smegmatis_MC2_155 LGECPGGTTVYACGPAPMLTMLRTALVGRDDVELHFERFAAPPVVDGTEF
TH_3804|M.thermoresistible__bu LGACPDGTAVYACGPPAMLTAIRAELAGRRNVELHFERFAAPPVVDGRPF
Mflv_3426|M.gilvum_PYR-GCK LGDCPADTSVYACGPAPMLTAVRDALVGRDDVELHFERFAAPPVVDGRPF
Mvan_3180|M.vanbaalenii_PYR-1 LGDCADGTAVYACGPAPMLTAVRAALVGRDDVELHFERFAAPPVTDGRPF
MAB_0088c|M.abscessus_ATCC_199 LPGVGENDAVYCCGPAPMLAVLQRRLLEMPSVELHFERFAAAPVVDGHPF
MUL_2159|M.ulcerans_Agy99 VAGAGLKTAVYVCGPPPMLEAVRAARAEYPCAPLHYERFSPPPVVDGVPF
MMAR_1933|M.marinum_M VAGAGPKTAVYVCGPPPMLEAVRAARAEYPCAPLHYERFSPPPVVDGVPF
Mb2798c|M.bovis_AF2122/97 LAGAGPTTAVYVCGPPGMLEAVRVARNQHADAPLHYERFSPPPVVDGVPF
Rv2776c|M.tuberculosis_H37Rv LAGAGPTTAVYVCGPPGMLEAVRVARNQHADAPLHYERFSPPPVVDGVPF
MAV_4119|M.avium_104 LAEAGPATAVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPF
: :** ***. ** :: . **:***...**.** *
MSMEG_3676|M.smegmatis_MC2_155 SVRIASTGQTVPVAADETLLAALNRAGVSAPYSCQQGFCGTCRVRALPRD
TH_3804|M.thermoresistible__bu SVRIASTGAEVPVGADETLLAALGRAGVQAPYSCQQGFCGTCRTRVL---
Mflv_3426|M.gilvum_PYR-GCK R--VAAAGVTVDVGVDETLLAALGRAGVTTPYSCRQGFCGTCRTRVL---
Mvan_3180|M.vanbaalenii_PYR-1 QATVASTGQQVDVGADETLLAALRRAGVDASYSCQQGFCGTCRTRVL---
MAB_0088c|M.abscessus_ATCC_199 EVQLGPGGPVLDVPADRTALDVIKKRLPHVAYSCQQGFCGTCKVNVL---
MUL_2159|M.ulcerans_Agy99 ELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVL---
MMAR_1933|M.marinum_M ELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVL---
Mb2798c|M.bovis_AF2122/97 ELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVL---
Rv2776c|M.tuberculosis_H37Rv ELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVL---
MAV_4119|M.avium_104 ELELARSRRVLTVPGNRSALDVMLDRDPATPYSCQQGFCGTCKVKVL---
:. : : :.: * .: ..***:*******:...*
MSMEG_3676|M.smegmatis_MC2_155 GDGAVQHRDTLLTEPERAAGYLLTCVSRAGNGQRLTIEL---
TH_3804|M.thermoresistible__bu -DGTVEHRDRLLTEPERAAGLMLTCVSRAPAGERLTLDL---
Mflv_3426|M.gilvum_PYR-GCK -SGEVDHRDTLLTDAERAAGLMLPCVSRAAEGTVLALDL---
Mvan_3180|M.vanbaalenii_PYR-1 -AGSVEHRDTLLTGPERAAGLMLTCVSRAGDGSGLTLDL---
MAB_0088c|M.abscessus_ATCC_199 -AGTVDHRDQILTESQRDEGQILTCVSRG-EG-RLVLDLPAE
MUL_2159|M.ulcerans_Agy99 -AGQVDHRGRAAQGDDE----MLVCVSRGHSA-RVVIDA---
MMAR_1933|M.marinum_M -AGQVDHRGRAAQGDDE----MLVCVSRGHSA-RVVIDA---
Mb2798c|M.bovis_AF2122/97 -AGQVDRRGRIIEGDNE----MLVCVSRAVSG-RVVIDA---
Rv2776c|M.tuberculosis_H37Rv -AGQVDRRGRIIEGDNE----MLVCVSRAVSG-RVVIDA---
MAV_4119|M.avium_104 -AGQVDRRGRTVEGDDE----MLVCVSRAKND-RLVIDA---
* *::*. :. :* ****. :.::