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LPMSDASRAVPLTVTEVIEESRDAISLVFSVPGEHRDRFGYRPGQFLTLRIPSEQTGSVARCYSLASSPH TDDAPKVTVKRTDGGYGSNWLCDNVSVGATLESLPPSGLFTPRDLDADFLLWAAGSGITPVMSILKSVLT AGTGRVVLCYANRDEASVIFAAELRDLAARYAGRFTVLHWLESIQGLPSHAQLSNFARLFTGYQSFICGP APYMAVVKETLTDVGIPRDHIHLEVFQSLHGDPFADVPVEPFPDEGQAAEAEISIDGRVHHLRWPVGRNL VDTMMAAGIEVPYSCREGNCGSCAATVIDGQVDLGNAAILEEQDIADGLFLACQACPLSDTVKIEF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2893 | - | - | 100% (347) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_5309 | - | e-101 | 51.02% (343) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_4186 | - | 3e-54 | 35.71% (336) | ferredoxin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3602 | hmp | 1e-103 | 52.71% (351) | hemoglobine-like protein |
| M. gilvum PYR-GCK | Mflv_1462 | - | 1e-101 | 51.59% (345) | ferredoxin |
| M. tuberculosis H37Rv | Rv3571 | hmp | 1e-103 | 52.71% (351) | hemoglobine-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0583c | - | 1e-104 | 53.59% (334) | putative oxidoreductase |
| M. marinum M | MMAR_5066 | hmp | 1e-104 | 54.34% (346) | flavodoxin reductase Hmp |
| M. avium 104 | MAV_0590 | - | 1e-100 | 52.56% (352) | oxidoreductase, electron transfer component |
| M. smegmatis MC2 155 | MSMEG_2893 | - | 1e-155 | 75.85% (352) | oxidoreductase, NAD/FAD-binding |
| M. thermoresistible (build 8) | TH_0316 | - | 1e-140 | 69.83% (348) | POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP |
| M. ulcerans Agy99 | MUL_4142 | hmp | 1e-104 | 54.34% (346) | flavodoxin reductase Hmp |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3602|M.bovis_AF2122/97 --MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPE
Rv3571|M.tuberculosis_H37Rv --MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPE
MMAR_5066|M.marinum_M --MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPR
MUL_4142|M.ulcerans_Agy99 --MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPR
MAV_0590|M.avium_104 --MTEADSAQALDEPLGDHVLELQIAEVIAETDDARSLVFAVPDDDGDPD
Mflv_1462|M.gilvum_PYR-GCK --MTDVAA----DEPLGAHVLELEIADVIDETSDARSLVFRSP---ADAP
MAB_0583c|M.abscessus_ATCC_199 --MT--------DVPLGKHVLEVRIAEVIEETADSRSLVFEIPDG-----
Mvan_2893|M.vanbaalenii_PYR-1 --MLPMSD--------ASRAVPLTVTEVIEESRDAISLVFSVP------G
MSMEG_2893|M.smegmatis_MC2_155 --MSDVES--------STRIARLTVTEVIDESHDARSLVFAVP------D
TH_0316|M.thermoresistible__bu MVDAEISR--------GPRAVRLTVAAVIDESPDARSLVFEVP------E
. : : :: *: *: :: **** *
Mb3602|M.bovis_AF2122/97 IPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTA
Rv3571|M.tuberculosis_H37Rv IPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTA
MMAR_5066|M.marinum_M IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
MUL_4142|M.ulcerans_Agy99 IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
MAV_0590|M.avium_104 IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
Mflv_1462|M.gilvum_PYR-GCK VAPEKLRYSPGQFLTLRVPSEKTGSVARCYSLCSSPFTGDPLTVTIKRTA
MAB_0583c|M.abscessus_ATCC_199 -AADKFAYAPGQYLTLRIPSDRTGSVARCYSLSSSPHLDDRLAVTVKRTA
Mvan_2893|M.vanbaalenii_PYR-1 EHRDRFGYRPGQFLTLRIPSEQTGSVARCYSLASSPHTDDAPKVTVKRTD
MSMEG_2893|M.smegmatis_MC2_155 EHRDHFGYRPGQFLTLRIPSERTGSVARCYSLASSPHTDDAHKVTVKRTD
TH_0316|M.thermoresistible__bu EHRTRFVYRPGQFLTLRIPGDRTGSVARCYSLASSPHTDDAMKVTVKRTD
:: * ***:****:*.::**********.***. .* **:***
Mb3602|M.bovis_AF2122/97 DGYASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMS
Rv3571|M.tuberculosis_H37Rv DGYASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMS
MMAR_5066|M.marinum_M DGYASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMS
MUL_4142|M.ulcerans_Agy99 DGYASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMS
MAV_0590|M.avium_104 DGYASNWLCDNARPGMRIHVLAPSGNFVPKTLGDDFLLMAAGSGITPIMS
Mflv_1462|M.gilvum_PYR-GCK DGYASNWLCDNAHAGMKMHVLAPSGTFVPKNLDTDFLLLAAGSGITPMLA
MAB_0583c|M.abscessus_ATCC_199 DGYGSNWICDNAHAGMHMHVLAPSGVFVPKQLDNDFLLLAGGSGVTPMMA
Mvan_2893|M.vanbaalenii_PYR-1 GGYGSNWLCDNVSVGATLESLPPSGLFTPRDLDADFLLWAAGSGITPVMS
MSMEG_2893|M.smegmatis_MC2_155 GGYGSNWLCDNVSVGSTIESLPPSGVFTPASLDDDFLLWAAGSGITPVMS
TH_0316|M.thermoresistible__bu GGYGSNWLCDNAEPGTTIEALPPAGTFTPASLDGAFLLWAAGSGITPVMS
.**.***:**:. * :. *.*:* *.* *. *** *.***:**:::
Mb3602|M.bovis_AF2122/97 ICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLES
Rv3571|M.tuberculosis_H37Rv ICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLES
MMAR_5066|M.marinum_M ICKSTLAEGSGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLES
MUL_4142|M.ulcerans_Agy99 ICKSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLES
MAV_0590|M.avium_104 IAKSALSEGSGRVTLLYANRDERSVIFADALRELSAKYPDRLTVLHWLES
Mflv_1462|M.gilvum_PYR-GCK ILKSALSEGSGHVTLVYANRDEKSVIFAETLRDLANKYPDRLTTIHWLES
MAB_0583c|M.abscessus_ATCC_199 ICKSALSQGSGKVVLIYANRDEQSVIFGAALRELAAKYPDRLTVIHWLES
Mvan_2893|M.vanbaalenii_PYR-1 ILKSVLTAGTGRVVLCYANRDEASVIFAAELRDLAARYAGRFTVLHWLES
MSMEG_2893|M.smegmatis_MC2_155 ILKSVLSAGSGRVILCYANRDERSVIFAAELRELAARHAGRLTVLHWLES
TH_0316|M.thermoresistible__bu ILKSVLEAGTGRVILCYANRDERSVIFAGELRELAARHAGRFTVLHWLES
* **.* * *:* * *****: ****. **:*: ::..*:*.:*****
Mb3602|M.bovis_AF2122/97 LQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHI
Rv3571|M.tuberculosis_H37Rv LQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHI
MMAR_5066|M.marinum_M LQGLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHI
MUL_4142|M.ulcerans_Agy99 LQGLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHI
MAV_0590|M.avium_104 LQGLPSVTALAQLAAPYTDRPVYICGPGAFMDSAREALETLKVPAAQIHI
Mflv_1462|M.gilvum_PYR-GCK VQGLPSVSALTALFAPFTSREAFICGPGPFMAAAEEALTASGAAADKIHI
MAB_0583c|M.abscessus_ATCC_199 VQGLPSQQQLATLTAPFAEHEAFICGPGPFMDASEAALKGNGMPHDRVHI
Mvan_2893|M.vanbaalenii_PYR-1 IQGLPSHAQLSNFARLFTGYQSFICGPAPYMAVVKETLTDVGIPRDHIHL
MSMEG_2893|M.smegmatis_MC2_155 VQGLPTRAQLCGFAQLFSGYESFICGPEPFMAVVRAALTEAGVPRRRIHL
TH_0316|M.thermoresistible__bu VQGLPTTAQMYRFARLFTDHESFVCGPEPFMAVVTAALTEAGVPRNQIHT
:****: : : :: ::*** .:* :* . ::*
Mb3602|M.bovis_AF2122/97 EVFKSLESDPFAAVK---VDDSG---DEAPATAVVELDGQTHTVSWPRTA
Rv3571|M.tuberculosis_H37Rv EVFKSLESDPFAAVK---VDDSG---DEAPATAVVELDGQTHTVSWPRTA
MMAR_5066|M.marinum_M EVFKSLESDPFAAVT---VEDSA---AEPPATAVVELDGQTHTVSWPRSA
MUL_4142|M.ulcerans_Agy99 EVFKSLESDPFAAVT---VEDSA---AEPPATAVVELDGQTHTVSWPRSA
MAV_0590|M.avium_104 EVFKSLDSDPFAAVK---IEDTAE-GDEPPATAVVELDGETHTVSWPRNA
Mflv_1462|M.gilvum_PYR-GCK EVFKSLDSDPFAAVT---IDDADDEGDSGPATVVVTLDGETHEVSWPRKA
MAB_0583c|M.abscessus_ATCC_199 EVFRSLESDPFAEVV---LAEPSD-DDEPPATATVELDGETHEVSWPRST
Mvan_2893|M.vanbaalenii_PYR-1 EVFQSLHGDPFAD-----VPVEPFPDEGQAAEAEISIDGRVHHLRWPVGR
MSMEG_2893|M.smegmatis_MC2_155 EVFQSLSGDPFAEDVPASGPAGPGTDAG-AAEAEIELDGTVHQLRWPRDR
TH_0316|M.thermoresistible__bu EVFRSLTGDPFTDEP-VGEPDGTIADERPPAEAVVVLDGETHVCEWPRTA
***:** .***: .* . : :** .* **
Mb3602|M.bovis_AF2122/97 KLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEG
Rv3571|M.tuberculosis_H37Rv KLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEG
MMAR_5066|M.marinum_M KLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDG
MUL_4142|M.ulcerans_Agy99 KLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDG
MAV_0590|M.avium_104 KLLDVLLAKGLDAPFSCREGHCGACACTLRKGQVSMEVNDVLEQQDLDEG
Mflv_1462|M.gilvum_PYR-GCK KLLDVLLNKGLDAPFSCREGHCGACAVLKKSGDIEMEVNDVLEQQDLDEG
MAB_0583c|M.abscessus_ATCC_199 VLLDVLLAKGLDAPFSCREGHCMTCACVLKDGKVRMLVNDALSQNDIDDG
Mvan_2893|M.vanbaalenii_PYR-1 NLVDTMMAAGIEVPYSCREGNCGSCAATVIDGQVDLGNAAILEEQDIADG
MSMEG_2893|M.smegmatis_MC2_155 NLVDTMLAAGVEVPYSCREGSCGSCAATVLDGEIERGDTPILDAQDIADG
TH_0316|M.thermoresistible__bu TLLDTMLARGLDAPYSCREGNCGSCAATVLEGEVDRGHSDILDPQDVADG
*:*.:: *::.*:***** * :** *.: *. :*: :*
Mb3602|M.bovis_AF2122/97 LILACQSRPESDSVEVTYDE
Rv3571|M.tuberculosis_H37Rv LILACQSRPESDSVEVTYDE
MMAR_5066|M.marinum_M LILACQSHPESDSVEVTYDE
MUL_4142|M.ulcerans_Agy99 LILACQSHPESDSVEVTYDE
MAV_0590|M.avium_104 LILACQSHPESDSVEVTYDD
Mflv_1462|M.gilvum_PYR-GCK LILACQAHPTSDSVEVTFDE
MAB_0583c|M.abscessus_ATCC_199 YILACQAVPETDDVNVTFDE
Mvan_2893|M.vanbaalenii_PYR-1 LFLACQACPLSDTVKIEF--
MSMEG_2893|M.smegmatis_MC2_155 LFLACQARPVSDRIRIEF--
TH_0316|M.thermoresistible__bu LILACQTRPNSDSVRIEF--
:****: * :* :.: :