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VNYLALDDFSTPWLKVPDLLLPAYGETWVMVGVTMVLVVLIGTPAGIILHNTSTLGLFPNPRVFTVLNTV VNVGRSLPFLILMAAIIPVTRFLVGTTIGIAAAIVPMTVAGIPFFARLVQNALREVRSDVTDMGLVSGGS HVQVIRSVQLSEALPALAGALTVNTIAMIEYSAIAGSIGAGGVGHLAITYGYNRFDDNIMIATVIALIIT IQLVQFTGDRVVRALTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3885 | - | - | 100% (227) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_2906 | - | 9e-12 | 25.77% (194) | phosphonate ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_5599 | - | 2e-10 | 28.25% (177) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3783c | proW | 6e-08 | 26.88% (186) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_1209 | - | 9e-11 | 28.81% (177) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3757c | proW | 6e-08 | 26.88% (186) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2802c | - | 6e-35 | 35.32% (218) | ABC transporter permease |
| M. marinum M | MMAR_5300 | proW | 2e-07 | 25.25% (202) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_0319 | - | 4e-07 | 28.81% (177) | ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_5808 | - | 1e-103 | 81.94% (227) | binding-protein-dependent transport systems inner membrane |
| M. thermoresistible (build 8) | TH_2403 | - | 4e-67 | 54.84% (217) | binding-protein-dependent transport systems inner membrane |
| M. ulcerans Agy99 | MUL_4375 | proW | 4e-07 | 24.26% (202) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3783c|M.bovis_AF2122/97 -----------------MHYLMTHPGAAWALTVVHLRLS-LLPVLIGLMS
Rv3757c|M.tuberculosis_H37Rv -----------------MHYLMTHPGAAWALTVVHLRLS-LLPVLIGLMS
MMAR_5300|M.marinum_M -----------------MHYLMTHLGTAWALTMVHLRLS-LIPVLIGTAI
MUL_4375|M.ulcerans_Agy99 -----------------MHYLMTHLGTAWALTMVHLRLS-LIPVLIGTAI
MAV_0319|M.avium_104 -----------------MHYLLTHLDDAARLTVVHLRLS-LVPVLIGLAI
Mflv_1209|M.gilvum_PYR-GCK -----------------MRYLFTHLDDLWVLTLIHLRLS-LIPIVLGLLI
Mvan_3885|M.vanbaalenii_PYR-1 -MNYLALDDFSTPWLKVPDLLLPAYGETWVMVGVTMVLVVLIGTPAGIIL
MSMEG_5808|M.smegmatis_MC2_155 -MNLLAQQDFSTPWSEVHTLLLPAYGETWIMVGVTMTLVVLAGIPLGVVL
TH_2403|M.thermoresistible__bu VTSVLAAG--TVPLDEMAGLLFPALLDTLTMVGIVMTIVTLVGVPLGALV
MAB_2802c|M.abscessus_ATCC_199 ---------MTTNWERLRPQLFEAFGDTLYMVSITLVVGGLVGLALGVLL
*: :. : : : * *
Mb3783c|M.bovis_AF2122/97 AVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLP---LIIGTRILD
Rv3757c|M.tuberculosis_H37Rv AVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLP---LIIGTRILD
MMAR_5300|M.marinum_M AIPLGLFVQHAPTLRRLTTATASVVFTIPSLALFVVLP---LIIKTRILQ
MUL_4375|M.ulcerans_Agy99 AIPLGLFVQHAPTLRRLTTATASVVFTIPSLALFVVLP---LIIKMRILQ
MAV_0319|M.avium_104 ALPLGMLVQRRRFARRLTTAVASVVFTIPSLALFVVLP---MIIGTRILD
Mflv_1209|M.gilvum_PYR-GCK AVPLGALVQRTTALRRLTTVTASIIFTIPSLALFVVLP---LIIPTRILD
Mvan_3885|M.vanbaalenii_PYR-1 HNTSTLGLFPNPRVFTVLNTVVNVGRSLPFLILMAAIIPVTRFLVGTTIG
MSMEG_5808|M.smegmatis_MC2_155 HNTSEFGLRPNPSVFRVLNTMVNIGRSLPFLILMAAIIPVTRFLVGTTVG
TH_2403|M.thermoresistible__bu HNLAPGGLFENPTLHTVLSWTINIGRSLPFLILMAAIMPFTRFVTGTNIG
MAB_2802c|M.abscessus_ATCC_199 YTTRSGGLLQNRLLHTLLNVVVNIVRPIPFVVLIAALGPITLGVVGTTIG
: : . .: .:* : *:..: : :
Mb3783c|M.bovis_AF2122/97 EANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVE
Rv3757c|M.tuberculosis_H37Rv EANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVE
MMAR_5300|M.marinum_M EANVIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIARMLKVE
MUL_4375|M.ulcerans_Agy99 EANVIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIARMLKVE
MAV_0319|M.avium_104 EANVMVALTAYTAALLVRAVLEALDAVPAQISDAATAVGYPRLTRMMKVE
Mflv_1209|M.gilvum_PYR-GCK EANVIVALTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLTRMLKVE
Mvan_3885|M.vanbaalenii_PYR-1 IAAAIVPMTVAGIPFFARLVQNALREVRSDVTDMGLVSGGSHVQVIRSVQ
MSMEG_5808|M.smegmatis_MC2_155 IPAAIVPMTLAGVPFFARLVQNALREVNSDVADMGLVSGGNLLQVVRTVQ
TH_2403|M.thermoresistible__bu IAAAVVPMSLAGIAFFTRIVENSLRSVPPSVVQVARASGGSPLQIIRTAQ
MAB_2802c|M.abscessus_ATCC_199 TTAVVFVMIVAASFAIARIVEQNLVTIDPGVIEAARAVGAGPLRIIVTLL
. .:. : :.* * : * : . : : . . * : : .
Mb3783c|M.bovis_AF2122/97 LPLSIPVLVAGLRVVAVTNIAMVSVGSVIGIGGLG-TWFTAGYQTNKSDQ
Rv3757c|M.tuberculosis_H37Rv LPLSIPVLVAGLRVVAVTNIAMVSVGSVIGIGGLG-TWFTAGYQTNKSDQ
MMAR_5300|M.marinum_M LPLSIPVLVSGLRVVVVTNIAMVSVGAVIGIGGLG-TWFTAGYLMDKSDQ
MUL_4375|M.ulcerans_Agy99 LPLSIPVLVSGLRVVVVTNIAMVSVGAVIGIGGLG-TWFTAGYLMDKSDQ
MAV_0319|M.avium_104 LPLAVPVLIAGLRVVVVTNIAMVSVGSVIGIGGLG-SWFTQGYQTGKSDQ
Mflv_1209|M.gilvum_PYR-GCK LPLALPVLIASLRVVAVTNISMVAVGSVIGIGGLG-TWFTEGYQANKSDQ
Mvan_3885|M.vanbaalenii_PYR-1 LSEALPALAGALTVNTIAMIEYSAIAGSIGAGGVGHLAITYGYNRFDDNI
MSMEG_5808|M.smegmatis_MC2_155 LSEALPALAGALTVNVIAMIEYSAIAGSIGAGGVGNLAITYGYNRFDDNI
TH_2403|M.thermoresistible__bu LHEAVPSILGGLTINVIAMIEYSAIAGTIGAGGIGYVAVTYGYQRFDQGV
MAB_2802c|M.abscessus_ATCC_199 VPEALGPLILGYTFVLIGIVDMSAMAGLVGGGGLGDFAIVQGYQRFNWQV
: :: : . . : : ::.. :* **:* .. ** .
Mb3783c|M.bovis_AF2122/97 IVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGA
Rv3757c|M.tuberculosis_H37Rv IVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGA
MMAR_5300|M.marinum_M IVAGITVMFVLAILIDMVLNVAGRLATPWERSSRGRRRFR---SPIVGGA
MUL_4375|M.ulcerans_Agy99 IVAGITVMFVLAILIDMVLNVAGRLATPWERSSRGRRRFR---SPIVGGA
MAV_0319|M.avium_104 ILAGIIALFALAVAVDGLIVLGGRLVTPWAHAVRGGARRS-VVAPVVGGA
Mflv_1209|M.gilvum_PYR-GCK IIAGIVAIFVLAIVIDTLIMWLGKLLTPWTRAQPRSTRTQ-----KAGAS
Mvan_3885|M.vanbaalenii_PYR-1 MIATVIALIITIQLVQFTGDRVVRALTR----------------------
MSMEG_5808|M.smegmatis_MC2_155 MIATAVSLIITIQVVQFAGDRLVKALTR----------------------
TH_2403|M.thermoresistible__bu MAATIVILVCTVAVVQLIGDALVRFTTPHARARAARV-------------
MAB_2802c|M.abscessus_ATCC_199 TIVSTVIIIALVQAAQFFGNYLARKALRR---------------------
. :. : :
Mb3783c|M.bovis_AF2122/97 R
Rv3757c|M.tuberculosis_H37Rv R
MMAR_5300|M.marinum_M R
MUL_4375|M.ulcerans_Agy99 R
MAV_0319|M.avium_104 R
Mflv_1209|M.gilvum_PYR-GCK A
Mvan_3885|M.vanbaalenii_PYR-1 -
MSMEG_5808|M.smegmatis_MC2_155 -
TH_2403|M.thermoresistible__bu -
MAB_2802c|M.abscessus_ATCC_199 -