For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTNWERLRPQLFEAFGDTLYMVSITLVVGGLVGLALGVLLYTTRSGGLLQNRLLHTLLNVVVNIVRPIPF VVLIAALGPITLGVVGTTIGTTAVVFVMIVAASFAIARIVEQNLVTIDPGVIEAARAVGAGPLRIIVTLL VPEALGPLILGYTFVLIGIVDMSAMAGLVGGGGLGDFAIVQGYQRFNWQVTIVSTVIIIALVQAAQFFGN YLARKALRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2802c | - | - | 100% (220) | ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_1227 | - | 2e-09 | 31.65% (139) | ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_1225 | - | 2e-08 | 30.30% (165) | ABC transporter permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 2e-09 | 22.40% (183) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_1209 | - | 8e-12 | 28.49% (186) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 2e-09 | 22.40% (183) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0033 | - | 2e-09 | 30.22% (139) | hypothetical protein MMAR_0033 |
| M. avium 104 | MAV_0059 | - | 6e-08 | 23.26% (172) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_3057 | - | 4e-39 | 41.26% (206) | ABC-type metal ion transport system, permease component |
| M. thermoresistible (build 8) | TH_2403 | - | 7e-40 | 41.67% (204) | binding-protein-dependent transport systems inner membrane |
| M. ulcerans Agy99 | MUL_4374 | proZ | 6e-09 | 25.13% (187) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_3885 | - | 7e-35 | 35.32% (218) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M --------------------------------------------------
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M --------------------------------------------------
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 PENLTRGGSMSQPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAPP
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M --------------------------------------------------
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 NVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFDV
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M --------------------------------------------------
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 GSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIGV
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M --------------------------------------------------
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 VQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATTI
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M -----------------------------------------------MSV
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0059|M.avium_104 QPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSNL
TH_2403|M.thermoresistible__bu ----------------------------VTSVLAAG--TVPLDEMAGLLF
Mvan_3885|M.vanbaalenii_PYR-1 -----------------------------MNYLALDDFSTPWLKVPDLLL
MAB_2802c|M.abscessus_ATCC_199 -------------------------------------MTTNWERLRPQLF
MSMEG_3057|M.smegmatis_MC2_155 ------------------------------MNAFTEWLDDSILFTTDAVP
Mb3782c|M.bovis_AF2122/97 --------------------------MNFLQQALSYLLTASNWTGPVGLA
Rv3756c|M.tuberculosis_H37Rv --------------------------MNFLQQALSYLLTASNWTGPVGLA
MUL_4374|M.ulcerans_Agy99 --------------------------MNFLQQALSYLSTAANWTGSAGLA
MMAR_0033|M.marinum_M AGNDINVEGAVKGGAEGPPTAPTTPGRPSVGRWALQPLTCAFAVAGALAY
Mflv_1209|M.gilvum_PYR-GCK --------------------------------------MRYLFTHLDDLW
MAV_0059|M.avium_104 YSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQHHKAVGPAAPKSTLA
TH_2403|M.thermoresistible__bu PALLDTLTMVGIVMTIVTLVGVPLGALVHNLAPGGLFENPTLHTVLSWTI
Mvan_3885|M.vanbaalenii_PYR-1 PAYGETWVMVGVTMVLVVLIGTPAGIILHNTSTLGLFPNPRVFTVLNTVV
MAB_2802c|M.abscessus_ATCC_199 EAFGDTLYMVSITLVVGGLVGLALGVLLYTTRSGGLLQNRLLHTLLNVVV
MSMEG_3057|M.smegmatis_MC2_155 VAVGQTLQLVFVPFFFVVLLGIPLGVLLYVTAPGGLAPIRWLNSSLGVVV
Mb3782c|M.bovis_AF2122/97 VRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVG--------AV
Rv3756c|M.tuberculosis_H37Rv VRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVG--------AV
MUL_4374|M.ulcerans_Agy99 HRTAEHLEYTALAATASALVAIPIGLIIGHTGRGQLLVVS--------AV
MMAR_0033|M.marinum_M VTVADVSESERRSLSVSHLLQLLREHLVISLSATVLTCVVAIPVGIALTR
Mflv_1209|M.gilvum_PYR-GCK VLTLIHLRLSLIPIVLGLLIAVPLGALVQRTTALRRLTTVTASIIFTIPS
MAV_0059|M.avium_104 QLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSASVIGLVLGMVLAVAGI
*: :
TH_2403|M.thermoresistible__bu NIGR----------SLPFLILMAAIMPFTRFVTGTNIGIAA-------AV
Mvan_3885|M.vanbaalenii_PYR-1 NVGR----------SLPFLILMAAIIPVTRFLVGTTIGIAA-------AI
MAB_2802c|M.abscessus_ATCC_199 NIVR----------PIPFVVLIAALGPITLGVVGTTIGTTA-------VV
MSMEG_3057|M.smegmatis_MC2_155 NVTR----------SLPFLVLVIALWPLGRLLVGSSLGTVA-------AM
Mb3782c|M.bovis_AF2122/97 NGLR----------ALP----TLGVLLLGVLLFG--LGLGP-------PL
Rv3756c|M.tuberculosis_H37Rv NGLR----------ALP----TLGVLLLGVLLFG--LGLGP-------PL
MUL_4374|M.ulcerans_Agy99 NGLR----------ALP----TLGVLLLGVLLFG--LGLGP-------PI
MMAR_0033|M.marinum_M GSMRRYSKPIITVAGFGQAAPAIGLIALGAVVFG--IGQLG-------AI
Mflv_1209|M.gilvum_PYR-GCK ---------------------LALFVVLPLIIPTRILDEAN-------VI
MAV_0059|M.avium_104 SHARWLRWPARVYTDVFRGLPEVVIILLIGLGIGPIVGGLTNNNPYPLGI
. . :. :
TH_2403|M.thermoresistible__bu VPMSLAGIAFFTRIVENSLRSVPPSVVQVARASGGSPLQIIRTAQLHEAV
Mvan_3885|M.vanbaalenii_PYR-1 VPMTVAGIPFFARLVQNALREVRSDVTDMGLVSGGSHVQVIRSVQLSEAL
MAB_2802c|M.abscessus_ATCC_199 FVMIVAASFAIARIVEQNLVTIDPGVIEAARAVGAGPLRIIVTLLVPEAL
MSMEG_3057|M.smegmatis_MC2_155 VPLTIGTIPFLARLVESSLREVDSGKIDAARVVGATRWQIITKTLLPEAI
Mb3782c|M.bovis_AF2122/97 VALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNAL
Rv3756c|M.tuberculosis_H37Rv VALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNAL
MUL_4374|M.ulcerans_Agy99 VALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVVLRVEMPNAL
MMAR_0033|M.marinum_M VALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLSAFSTLRRVELPLSL
Mflv_1209|M.gilvum_PYR-GCK VALTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLTRMLKVELPLAL
MAV_0059|M.avium_104 AALGMMAAAYIGEILRSGIQSVDPGQLEASRALGFSYATAMRLVVVPQGV
: : : : : : . * : : .:
TH_2403|M.thermoresistible__bu PSILGGLTINVIAMIEYSAIAGTIGAGGIGYVAVTYGYQRFDQG-----V
Mvan_3885|M.vanbaalenii_PYR-1 PALAGALTVNTIAMIEYSAIAGSIGAGGVGHLAITYGYNRFDDN-----I
MAB_2802c|M.abscessus_ATCC_199 GPLILGYTFVLIGIVDMSAMAGLVGGGGLGDFAIVQGYQRFNWQ-----V
MSMEG_3057|M.smegmatis_MC2_155 SGIIAGLTITIIALLGFSALAGVIGGGGLGDLAIRYGARSYDGP-----V
Mb3782c|M.bovis_AF2122/97 PLMLGGLRSATLQVVATATVAAYASLGGLGGYLIDGIKERRFHI-----A
Rv3756c|M.tuberculosis_H37Rv PLMLGGLRSATLQVVATATVAAYASLGGLGGYLIDGIKERRFHI-----A
MUL_4374|M.ulcerans_Agy99 PLILGGLRSATLQVVATVTVAAYASLGGLGRYLIDGIKERQSHI-----A
MMAR_0033|M.marinum_M PVIVAGVRTALVLIVGTAALASFTGGGGLGQLITTGIKLQQPVT-----L
Mflv_1209|M.gilvum_PYR-GCK PVLIASLRVVAVTNISMVAVGSVIGIGGLGTWFTEGYQANKSDQ-----I
MAV_0059|M.avium_104 RRVLPALVNQFIALLKASALVYFLGLVADQRELFQVGRDLNAETGNLSPL
: . : : :: . .
TH_2403|M.thermoresistible__bu MAATIVILVCTVAVVQLIGDALVRFTTPHARARAA----------RV---
Mvan_3885|M.vanbaalenii_PYR-1 MIATVIALIITIQLVQFTGDRVVRALTR----------------------
MAB_2802c|M.abscessus_ATCC_199 TIVSTVIIIALVQAAQFFGNYLARKALRR---------------------
MSMEG_3057|M.smegmatis_MC2_155 LWSTVLLLIVFAQIFQVVGDYFARKTDHRARRSAG----------GAGDA
Mb3782c|M.bovis_AF2122/97 LVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL---------AAVVDK
Rv3756c|M.tuberculosis_H37Rv LVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL---------AAVVDK
MUL_4374|M.ulcerans_Agy99 LVGALMVAALALSLDGLLALAGWASVPGTGRVSRFWHQPDDRIDVAVSAN
MMAR_0033|M.marinum_M IVGAILVAALALFIDWLARLIEMVAAPRGL--------------------
Mflv_1209|M.gilvum_PYR-GCK IAGIVAIFVLAIVIDTLIMWLGKLLTPWTRAQPRS---------TRTQKA
MAV_0059|M.avium_104 VAAGACYLILTVPLTHLVNMIDARLRRGRAAVDPE---------EPAEML
.
TH_2403|M.thermoresistible__bu ----------
Mvan_3885|M.vanbaalenii_PYR-1 ----------
MAB_2802c|M.abscessus_ATCC_199 ----------
MSMEG_3057|M.smegmatis_MC2_155 GEAQRLSA--
Mb3782c|M.bovis_AF2122/97 PAAGGGHALR
Rv3756c|M.tuberculosis_H37Rv PAAGGGHALR
MUL_4374|M.ulcerans_Agy99 SAAVGSHVLR
MMAR_0033|M.marinum_M ----------
Mflv_1209|M.gilvum_PYR-GCK GASA------
MAV_0059|M.avium_104 TFGQEIT---