For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MHYLLTHLDDAARLTVVHLRLSLVPVLIGLAIALPLGMLVQRRRFARRLTTAVASVVFTIPSLALFVVLP MIIGTRILDEANVMVALTAYTAALLVRAVLEALDAVPAQISDAATAVGYPRLTRMMKVELPLAVPVLIAG LRVVVVTNIAMVSVGSVIGIGGLGSWFTQGYQTGKSDQILAGIIALFALAVAVDGLIVLGGRLVTPWAHA VRGGARRSVVAPVVGGAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0319 | - | - | 100% (228) | ABC transporter, permease protein |
| M. avium 104 | MAV_0320 | - | 3e-15 | 25.82% (213) | ABC transporter, permease protein |
| M. avium 104 | MAV_3399 | - | 3e-11 | 28.29% (205) | ABC transporter permease protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3783c | proW | 4e-91 | 74.24% (229) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_1209 | - | 1e-80 | 71.43% (210) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3757c | proW | 4e-91 | 74.24% (229) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 5e-08 | 29.05% (148) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_0263 | - | 1e-82 | 70.75% (212) | osmoprotectant ABC transporter ProW |
| M. marinum M | MMAR_5300 | proW | 5e-85 | 70.18% (228) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. smegmatis MC2 155 | MSMEG_6332 | - | 6e-83 | 72.86% (210) | amino acid ABC transporter, permease protein |
| M. thermoresistible (build 8) | TH_3904 | - | 1e-22 | 31.49% (181) | PUTATIVE conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_4375 | proW | 2e-84 | 69.74% (228) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_5599 | - | 1e-80 | 70.95% (210) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3783c|M.bovis_AF2122/97 ------------------------------------MHYLMTHPGAAWAL
Rv3757c|M.tuberculosis_H37Rv ------------------------------------MHYLMTHPGAAWAL
MMAR_5300|M.marinum_M ------------------------------------MHYLMTHLGTAWAL
MUL_4375|M.ulcerans_Agy99 ------------------------------------MHYLMTHLGTAWAL
MAV_0319|M.avium_104 ------------------------------------MHYLLTHLDDAARL
Mflv_1209|M.gilvum_PYR-GCK ------------------------------------MRYLFTHLDDLWVL
Mvan_5599|M.vanbaalenii_PYR-1 ------------------------------------MRYLVTHLDALWTL
MSMEG_6332|M.smegmatis_MC2_155 ------------------------------------MQYLLTHLDDLWEL
MAB_0263|M.abscessus_ATCC_1997 ------------------------------------MRYLFTHLGDAWQL
TH_3904|M.thermoresistible__bu VTATVDDTGDTGHTGCTGTAGDRASRSAARRWARRTVQPVLCLVAVGGAL
MLBr_02093|M.leprae_Br4923 --MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLL
:. *
Mb3783c|M.bovis_AF2122/97 TVVHLR--------------------------------LSLLPVLIGLMS
Rv3757c|M.tuberculosis_H37Rv TVVHLR--------------------------------LSLLPVLIGLMS
MMAR_5300|M.marinum_M TMVHLR--------------------------------LSLIPVLIGTAI
MUL_4375|M.ulcerans_Agy99 TMVHLR--------------------------------LSLIPVLIGTAI
MAV_0319|M.avium_104 TVVHLR--------------------------------LSLVPVLIGLAI
Mflv_1209|M.gilvum_PYR-GCK TLIHLR--------------------------------LSLIPIVLGLLI
Mvan_5599|M.vanbaalenii_PYR-1 SLIHLR--------------------------------LSLIPILLGLLI
MSMEG_6332|M.smegmatis_MC2_155 TVIHLR--------------------------------LSLVPIVLGLLI
MAB_0263|M.abscessus_ATCC_1997 SLIHLR--------------------------------LSLVPILIGLAI
TH_3904|M.thermoresistible__bu AYVHLADVSESEKRSLGVPHLLMLLRQHME--------ISLAATVLTCAI
MLBr_02093|M.leprae_Br4923 SVVVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIM
: : ** ::
Mb3783c|M.bovis_AF2122/97 AVPLG-------LLVQRAPLLRRLTTATASVIF--TIPSLALFVVLPLII
Rv3757c|M.tuberculosis_H37Rv AVPLG-------LLVQRAPLLRRLTTATASVIF--TIPSLALFVVLPLII
MMAR_5300|M.marinum_M AIPLG-------LFVQHAPTLRRLTTATASVVF--TIPSLALFVVLPLII
MUL_4375|M.ulcerans_Agy99 AIPLG-------LFVQHAPTLRRLTTATASVVF--TIPSLALFVVLPLII
MAV_0319|M.avium_104 ALPLG-------MLVQRRRFARRLTTAVASVVF--TIPSLALFVVLPMII
Mflv_1209|M.gilvum_PYR-GCK AVPLG-------ALVQRTTALRRLTTVTASIIF--TIPSLALFVVLPLII
Mvan_5599|M.vanbaalenii_PYR-1 AVPLG-------ALVQRTTVLRRLTTVTASIVF--TIPSLALFVVLPLII
MSMEG_6332|M.smegmatis_MC2_155 AVPLG-------ALVQRTTTLRRLTTVAASIIF--TIPSLALFVALPLII
MAB_0263|M.abscessus_ATCC_1997 AIPCG-------ALLHRRRTVRRVTTVIASIVF--TIPSLALFVALPLII
TH_3904|M.thermoresistible__bu AIPLG-------VALTRGRFRRFATPIITVSGFGQAAPAIGLIALGAVLF
MLBr_02093|M.leprae_Br4923 AVPLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIAT
*:* * * * : : :: :
Mb3783c|M.bovis_AF2122/97 GTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIA
Rv3757c|M.tuberculosis_H37Rv GTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIA
MMAR_5300|M.marinum_M KTRILQEANVIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIA
MUL_4375|M.ulcerans_Agy99 KMRILQEANVIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIA
MAV_0319|M.avium_104 GTRILDEANVMVALTAYTAALLVRAVLEALDAVPAQISDAATAVGYPRLT
Mflv_1209|M.gilvum_PYR-GCK PTRILDEANVIVALTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLT
Mvan_5599|M.vanbaalenii_PYR-1 PTRILDEANVIVALTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLT
MSMEG_6332|M.smegmatis_MC2_155 PTRILDEANVIVALTLYTTALLVRAVPEALDAVPEHVRDAATAVGYRPLT
MAB_0263|M.abscessus_ATCC_1997 PTRILDEANVMVALTLYTTALLIRAVPEALDAIAPQVRDAATAVGYRPLA
TH_3904|M.thermoresistible__bu G---IGAVGAVAALTVYGALPIIANTVTGLNGVDDRLIEAARGMGMPTST
MLBr_02093|M.leprae_Br4923 LGFQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWK
. ** :: . * : : :*. .:*
Mb3783c|M.bovis_AF2122/97 QMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIG----------IGGL
Rv3757c|M.tuberculosis_H37Rv QMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIG----------IGGL
MMAR_5300|M.marinum_M RMLKVELPLSIPVLVSGLRVVVVTNIAMVSVGAVIG----------IGGL
MUL_4375|M.ulcerans_Agy99 RMLKVELPLSIPVLVSGLRVVVVTNIAMVSVGAVIG----------IGGL
MAV_0319|M.avium_104 RMMKVELPLAVPVLIAGLRVVVVTNIAMVSVGSVIG----------IGGL
Mflv_1209|M.gilvum_PYR-GCK RMLKVELPLALPVLIASLRVVAVTNISMVAVGSVIG----------IGGL
Mvan_5599|M.vanbaalenii_PYR-1 RMLKIELPLALPVLIASLRVVAVTNISMVAVGSVIG----------IGGL
MSMEG_6332|M.smegmatis_MC2_155 RMLKVELPLSIPVLVASLRVVAVTNISMVSVGSVIG----------IGGL
MAB_0263|M.abscessus_ATCC_1997 RLVRVELPLSIPVLVAGLRVVAVTNISMVSVGSVIG----------IGGL
TH_3904|M.thermoresistible__bu TLLRVELPLALPVIIAGVRTALVLIVGTAALASFTG----------AGGL
MLBr_02093|M.leprae_Br4923 TIVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGN
:::: :*:: * :::.: . :. .: . .*
Mb3783c|M.bovis_AF2122/97 GTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRA
Rv3757c|M.tuberculosis_H37Rv GTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRA
MMAR_5300|M.marinum_M GTWFTAGYLMDKSDQIVAGITVMFVLAILIDMVLNVAGRLATPWERSSRG
MUL_4375|M.ulcerans_Agy99 GTWFTAGYLMDKSDQIVAGITVMFVLAILIDMVLNVAGRLATPWERSSRG
MAV_0319|M.avium_104 GSWFTQGYQTGKSDQILAGIIALFALAVAVDGLIVLGGRLVTPWAHAVRG
Mflv_1209|M.gilvum_PYR-GCK GTWFTEGYQANKSDQIIAGIVAIFVLAIVIDTLIMWLGKLLTPWTRAQPR
Mvan_5599|M.vanbaalenii_PYR-1 GTWFTEGYQANKSDQIIAGIVAIFVLAIVIDTLIMLAGKALTPWTRAQPR
MSMEG_6332|M.smegmatis_MC2_155 GTWFTEGYQSNKSSQIIAGIIAIFVLAIVVDTLIMLAGKLIAPWNRAEVT
MAB_0263|M.abscessus_ATCC_1997 GTWFTEGYQANKSSQIIAGIVAIFLLAVIVDSLLVVLGRVATPWARATKT
TH_3904|M.thermoresistible__bu GQLITTGIKLQQTVTLIVGAVLVAALALFIDWLARMVEVVAAPKGL----
MLBr_02093|M.leprae_Br4923 MASLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFRFLATR
:. : .* : *: : : :.
Mb3783c|M.bovis_AF2122/97 ARRRRQVAAPITGGAR
Rv3757c|M.tuberculosis_H37Rv ARRRRQVAAPITGGAR
MMAR_5300|M.marinum_M RRRFR---SPIVGGAR
MUL_4375|M.ulcerans_Agy99 RRRFR---SPIVGGAR
MAV_0319|M.avium_104 GARRS-VVAPVVGGAR
Mflv_1209|M.gilvum_PYR-GCK STRTQKAGASA-----
Mvan_5599|M.vanbaalenii_PYR-1 ATRAPRAEAGAPT---
MSMEG_6332|M.smegmatis_MC2_155 A---------------
MAB_0263|M.abscessus_ATCC_1997 AGAT------------
TH_3904|M.thermoresistible__bu ----------------
MLBr_02093|M.leprae_Br4923 RCSGCR----------