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LLRVTAGPSTVESFPVIEIENLTKRFGDRTVLDDISLSVGSGEILAVVGPSGAGKSTLSRCVSFLERPTS GTVRVDGKDFTRLDGDELLAARRNVGVIFQTAPLLRRRTVAQNIALPLQYLHATEGSAGTRVTELLDRVG LADRRDFYPAQLSGGQKQRVGIARALALGPSNLLSDEATSGLDPATTRSILALLSHLRDEFGLSIILITH EMEVVREIADSVARIEDGRIIESGSVQDVILDPASELARELLPDRPSVPLDGAGEIWEVSHASRTVPLDW LTSIQSAPGLSGAAVSVLSASVESIRGVAVGRAVLAITPSAPSGFVEYLTERGLHVRPVEKVAAGSAEAA A
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3884 | - | - | 100% (351) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2428 | - | 5e-46 | 39.43% (246) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4704 | - | 3e-44 | 43.10% (239) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-40 | 37.29% (236) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3581 | - | 1e-45 | 40.32% (248) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-40 | 37.29% (236) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01122 | - | 1e-36 | 37.96% (245) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2803c | - | 4e-65 | 43.31% (344) | methionine import ATP-binding protein metN |
| M. marinum M | MMAR_0034 | proV_1 | 1e-38 | 32.23% (301) | osmoprotectant (glycine |
| M. avium 104 | MAV_1785 | - | 2e-38 | 36.44% (236) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_5807 | - | 1e-138 | 81.49% (308) | D-methionine transport ATP-binding protein MetN |
| M. thermoresistible (build 8) | TH_2538 | - | 2e-74 | 58.47% (248) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_0033 | proV_1 | 9e-39 | 32.23% (301) | osmoprotectant (glycine |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 MSPLLEVTDLAVTFETNGEPVTAVRGISYRINAGEVVAMVGESGSGKSAA
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 AMAVVGLLPEYAQVRGSVRLHNTELVGLADKTMSRFRGKAIGTVFQDPMS
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 ALTPVYTVGDQITEAIKVHQPRVGKKAAHRRAVELLELVGITQPDRRARA
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 FPHELSGGERQRVVIATAIANDPDLLICDEPTTALDVTVQAQILEVLKTA
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 RDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVESAQVSTLYRERQMPY
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 TVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQECPFAPRCPLVVDECR
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
MMAR_0034|M.marinum_M --------------------------------------------------
MUL_0033|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 ---------------------------------------------MLRVT
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK -------------------------------------MTTSENS------
MLBr_01122|M.leprae_Br4923 LREPELVEVRAGHRTACIRTDQVSGRSAADIYGINTDTRTSATSDSSVVV
Mb2419c|M.bovis_AF2122/97 -------------------------------------------------M
Rv2397c|M.tuberculosis_H37Rv -------------------------------------------------M
MAV_1785|M.avium_104 -------------------------------------------------M
MMAR_0034|M.marinum_M ---------------------------------------MPEAASADQPT
MUL_0033|M.ulcerans_Agy99 ---------------------------------------MPEAASADQPT
Mvan_3884|M.vanbaalenii_PYR-1 AGPSTVESFPVIEIENLTKRFG----DRTVLDDISLSVGSGEILAVVGPS
MSMEG_5807|M.smegmatis_MC2_155 ----------MIEIENLTKRFG----DRTVLDEVSLSVAAGEILAVVGPS
TH_2538|M.thermoresistible__bu ----------MIELTDLTKVYGCGEHRTVVLDRINFRVETGEVLAVVGPS
MAB_2803c|M.abscessus_ATCC_199 ----MGDVAPLIQFQNVTKTFRVGKKTVTAVDDVSLDIGSGDVFAMIGYS
Mflv_3581|M.gilvum_PYR-GCK -------AHPMVKAELVCKDFG----ALKVLKGITLEVQKGQVLVLVGPS
MLBr_01122|M.leprae_Br4923 RVRDLVKTYRLTKGVGLRRAIG----EIRAVNGVSFELQQGRTLGIVGES
Mb2419c|M.bovis_AF2122/97 T--------YAIVVADATKRYG----DFVALDHVDFVVPTGSLTALLGPS
Rv2397c|M.tuberculosis_H37Rv T--------YAIVVADATKRYG----DFVALDHVDFVVPTGSLTALLGPS
MAV_1785|M.avium_104 TDAGTDRGDIAITVRDAYKRYG----DFVALDHVDFVVPTGSLTALLGPS
MMAR_0034|M.marinum_M TSDAPQSSGLRILLDGVTKRYGV--RSTPAVDNVTLEIGAGEIVMLVGPS
MUL_0033|M.ulcerans_Agy99 TSDAPQSSGLRILLDGVTKRYGV--RSTPAVDNVTLEIGAGEIVMLVGPS
: .:. : : : * ::* *
Mvan_3884|M.vanbaalenii_PYR-1 GAGKSTLSRCVSFLERPTSGTVRVDGKDFTRLDGDE---------LLAAR
MSMEG_5807|M.smegmatis_MC2_155 GAGKSTLSRCVSALERPTSGTVRVDGKDFSRLDGTE---------LIAAR
TH_2538|M.thermoresistible__bu GAGKSTLAQCINLLTRPTSGSVVVNGEDLTTLSTHR---------LRVAR
MAB_2803c|M.abscessus_ATCC_199 GAGKSTLVRLINGLERPTSGRVIVDGAEVSALGERE---------LRGLR
Mflv_3581|M.gilvum_PYR-GCK GSGKSTLLRCINHLETVSAGRLYVDGTLVGYHERGGKLYEMKPRDVARQR
MLBr_01122|M.leprae_Br4923 GSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNRAS---------RRSMR
Mb2419c|M.bovis_AF2122/97 GSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ--------------R
Rv2397c|M.tuberculosis_H37Rv GSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ--------------R
MAV_1785|M.avium_104 GSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQ--------------R
MMAR_0034|M.marinum_M GCGKTTTMKMINRLIEPTSGRIFIGDDDVTRRNPDE------------LR
MUL_0033|M.ulcerans_Agy99 GCGKTTTMKVINRLIEPTSGRIFIGDDDVTRRNPDE------------LR
*.**:* : : * :* : : . . *
Mvan_3884|M.vanbaalenii_PYR-1 RNVGVIFQT--APLLRRRTVAQNIALPLQYLHATEGSAGTRVTELLDRVG
MSMEG_5807|M.smegmatis_MC2_155 RGVGVIFQS--APLLRRRTVARNIALPLEYLGATQSSIDKRVSELLERVG
TH_2538|M.thermoresistible__bu RRIGTVFQS--SGLLERRTAAENVALPLEYLGVTAAETRKRVAELLDRVG
MAB_2803c|M.abscessus_ATCC_199 SDIGMIFQQ--FNLFRSRTVAGNIAYPLRVAGWTADKRNARVAELLEFVG
Mflv_3581|M.gilvum_PYR-GCK RDVGMVFQH-FNLFPHRTALGNVVEAPIQVKGVKKDEAVTRGRELLAQVG
MLBr_01122|M.leprae_Br4923 RNIQVVFQDPVASLDPRLPVFELIAEPLHANGFSKNYTQMRVAELLDIVG
Mb2419c|M.bovis_AF2122/97 RGIGFVFQH--YAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVG
Rv2397c|M.tuberculosis_H37Rv RGIGFVFQH--YAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVG
MAV_1785|M.avium_104 RGIGFVFQH--YAAFKHLTVRDNVAYGLKVRKRPKAEIKAKVDNLLEVVG
MMAR_0034|M.marinum_M RHIGYVVQG--AGLFPHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVN
MUL_0033|M.ulcerans_Agy99 RHIGYVVQG--AGVFLHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVN
: :.* . : . : :** *.
Mvan_3884|M.vanbaalenii_PYR-1 LA--DRRDFYPAQLSGGQKQRVGIARALALGPSNLLSDEATSGLDPATTR
MSMEG_5807|M.smegmatis_MC2_155 LT--DRASYLPAQLSGGQKQRVGIARALALGPSNLLSDEATSGLDPATTK
TH_2538|M.thermoresistible__bu LA--ARANHYPFQLSGGQRQRVGIARALALRPSVLLSDEATAGLDPTTTA
MAB_2803c|M.abscessus_ATCC_199 LG--DKAKSYPDQLSGGQKQRVGIARALATSPSVLLADEATSALDPETTS
Mflv_3581|M.gilvum_PYR-GCK LA--DKADAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVG
MLBr_01122|M.leprae_Br4923 LRR-DDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSIQA
Mb2419c|M.bovis_AF2122/97 LS--GFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
Rv2397c|M.tuberculosis_H37Rv LS--GFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
MAV_1785|M.avium_104 LS--GFQGRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVRE
MMAR_0034|M.marinum_M LDPAQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQ
MUL_0033|M.ulcerans_Agy99 LDPAQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQ
* * ::****:**:.:***** * : **. ..:*
Mvan_3884|M.vanbaalenii_PYR-1 SILALLSHLRDEFGLSIILITHEMEVVREIADSVARIEDG-RIIESGSVQ
MSMEG_5807|M.smegmatis_MC2_155 SILELLSHLRDEYALSIILITHEMEVVREIADSVARLDGG-RIIESGRVD
TH_2538|M.thermoresistible__bu SVVELLRELRDDLNLSIVFITHEMDTVLKIADSVARLDHG-RIVEAGRLV
MAB_2803c|M.abscessus_ATCC_199 DVLRLLREVNAEFGVTIVVITHEMDVVRTVADHVAVLADG-KVVETGTVF
Mflv_3581|M.gilvum_PYR-GCK EVLAVMKKLAAQG-MTMVVVTHEMGFAREVADELVFMDEG-VVVERGNPR
MLBr_01122|M.leprae_Br4923 GIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAG-TIVEQGDSH
Mb2419c|M.bovis_AF2122/97 ELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKG-RIEQVGSPT
Rv2397c|M.tuberculosis_H37Rv ELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKG-RIEQVGSPT
MAV_1785|M.avium_104 DLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQG-RIEQIGSPT
MMAR_0034|M.marinum_M RLQDELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPE
MUL_0033|M.ulcerans_Agy99 RLQDELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPE
: : : : :.::*: :.. :. : * : : .
Mvan_3884|M.vanbaalenii_PYR-1 DVILDPASELARELLPDRPSVPL-DGAG--EIWEVS---HASRTVPLDWL
MSMEG_5807|M.smegmatis_MC2_155 DIILDPDSTLARELLPDRPGALA-PGAG--EVWEVS---YASREVPLDWL
TH_2538|M.thermoresistible__bu DLLTDPASALGADLRPQGAAAPP-APPXXXRLRGVAGPDHPHRTGAVRAA
MAB_2803c|M.abscessus_ATCC_199 DVFSTPQSEAGKRFVGTVLRNTP-SGED---IARIAQR-HKGRIVAVEIS
Mflv_3581|M.gilvum_PYR-GCK EVMSNPQHERTKAFLSKVM-------------------------------
MLBr_01122|M.leprae_Br4923 DVFRNPQHDYTRRLLGAIPRPEV-G-------------------------
Mb2419c|M.bovis_AF2122/97 DVYDAPANAFVMSFLGAVSTLNG-SLVRPHDIRVGRTPNMAVAAADGTAG
Rv2397c|M.tuberculosis_H37Rv DVYDAPANAFVMSFLGAVSTLNG-SLVRPHDIRVGRTPNMAVAAADGTAG
MAV_1785|M.avium_104 EVYDAPTNAFVMSFLGAVSTLNG-TLVRPHDIRVGRTPEMAVAAEDGTAE
MMAR_0034|M.marinum_M RILAEPANDFVRGFVGAGATLMQLSLTRVRDIDLH---EAVVAQAGGDPA
MUL_0033|M.ulcerans_Agy99 RVLAEPANDFVRGFVGAGATLMQLSLTRVRDIDLH---EAVVAQAGGDPA
: * :
Mvan_3884|M.vanbaalenii_PYR-1 TSIQSAPGLS-----GAAVSVLSASVESIRGVAVGRAVLAI---TPSAPS
MSMEG_5807|M.smegmatis_MC2_155 TSIQSAPGLG-----DAKISVLSASIEAIRGVAVGRATLSI---EPAAPT
TH_2538|M.thermoresistible__bu GRTGPAAARR-----CGGGTAVDAGSDRRVADRAGRRPGRR---DDAVAA
MAB_2803c|M.abscessus_ATCC_199 EGVQIGPALARATELGVRFEVVYGGITTLQSRSFGNLTLELEGPDDQVAH
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 STGVLRAVVDRVVVLGFEVR------VELTSAATGGAFTAQITRGDAEAL
Rv2397c|M.tuberculosis_H37Rv STGVLRAVVDRVVVLGFEVR------VELTSAATGGAFTAQITRGDAEAL
MAV_1785|M.avium_104 STGVARAIVDRVVKLGFEVR------VELTSAATGGPFTAQITRGDAEAL
MMAR_0034|M.marinum_M EAVELAGSLDREHAIVLDRQNRPLRWLPLEELAKPQALAQVTRDDDLECV
MUL_0033|M.ulcerans_Agy99 EAVELAGSLDRAHAIVLDRQNRPLRWLPLEELAKPQALAQVTRDDDLECV
Mvan_3884|M.vanbaalenii_PYR-1 GFVEYLTERGLHVRPVEKVAAGSAEAAA----------------------
MSMEG_5807|M.smegmatis_MC2_155 ---------RLRRAPA----------------------------------
TH_2538|M.thermoresistible__bu P----------RRRPIRP--------------------------------
MAB_2803c|M.abscessus_ATCC_199 VVS-----DLSAVTTVQRVAR-----------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01122|M.leprae_Br4923 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 ALR-----EGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST----
Rv2397c|M.tuberculosis_H37Rv ALR-----EGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST----
MAV_1785|M.avium_104 ALR-----EGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA----
MMAR_0034|M.marinum_M NLASTLNDALDEMLTSSHGVVVVTGRRNTYQGVIRVETIMEAIADIRGAA
MUL_0033|M.ulcerans_Agy99 NLASTLNDALDEMLTSAHGVVVVTGRRNTYQGVIRVETIMEAIADIRGAA
Mvan_3884|M.vanbaalenii_PYR-1 -------
MSMEG_5807|M.smegmatis_MC2_155 -------
TH_2538|M.thermoresistible__bu -------
MAB_2803c|M.abscessus_ATCC_199 -------
Mflv_3581|M.gilvum_PYR-GCK -------
MLBr_01122|M.leprae_Br4923 -------
Mb2419c|M.bovis_AF2122/97 -------
Rv2397c|M.tuberculosis_H37Rv -------
MAV_1785|M.avium_104 -------
MMAR_0034|M.marinum_M NSEEPDT
MUL_0033|M.ulcerans_Agy99 NSEEPDT